Type |
Details |
Score |
Publication |
First Author: |
Estrach S |
Year: |
2006 |
Journal: |
Development |
Title: |
Jagged 1 is a beta-catenin target gene required for ectopic hair follicle formation in adult epidermis. |
Volume: |
133 |
Issue: |
22 |
Pages: |
4427-38 |
|
•
•
•
•
•
|
Publication |
First Author: |
Watson EC |
Year: |
2016 |
Journal: |
Development |
Title: |
Apoptosis regulates endothelial cell number and capillary vessel diameter but not vessel regression during retinal angiogenesis. |
Volume: |
143 |
Issue: |
16 |
Pages: |
2973-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Campbell DP |
Year: |
2016 |
Journal: |
Sci Rep |
Title: |
Canonical Notch signaling plays an instructive role in auditory supporting cell development. |
Volume: |
6 |
|
Pages: |
19484 |
|
•
•
•
•
•
|
Publication |
First Author: |
Khandanpour C |
Year: |
2013 |
Journal: |
Cancer Cell |
Title: |
Growth factor independence 1 antagonizes a p53-induced DNA damage response pathway in lymphoblastic leukemia. |
Volume: |
23 |
Issue: |
2 |
Pages: |
200-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Baghdadi MB |
Year: |
2018 |
Journal: |
Cell Stem Cell |
Title: |
Notch-Induced miR-708 Antagonizes Satellite Cell Migration and Maintains Quiescence. |
Volume: |
23 |
Issue: |
6 |
Pages: |
859-868.e5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Magenheim J |
Year: |
2011 |
Journal: |
Dev Biol |
Title: |
Ngn3(+) endocrine progenitor cells control the fate and morphogenesis of pancreatic ductal epithelium. |
Volume: |
359 |
Issue: |
1 |
Pages: |
26-36 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
448
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Chandrakesan P |
Year: |
2017 |
Journal: |
Mol Cancer |
Title: |
Dclk1, a tumor stem cell marker, regulates pro-survival signaling and self-renewal of intestinal tumor cells. |
Volume: |
16 |
Issue: |
1 |
Pages: |
30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Andersson ER |
Year: |
2018 |
Journal: |
Gastroenterology |
Title: |
Mouse Model of Alagille Syndrome and Mechanisms of Jagged1 Missense Mutations. |
Volume: |
154 |
Issue: |
4 |
Pages: |
1080-1095 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang Y |
Year: |
2007 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Conserved signal peptide of Notch3 inhibits interaction with proteasome. |
Volume: |
355 |
Issue: |
1 |
Pages: |
245-51 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
2318
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1964
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1154
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1964
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu P |
Year: |
2016 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Anabolic actions of Notch on mature bone. |
Volume: |
113 |
Issue: |
15 |
Pages: |
E2152-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vanderkerken M |
Year: |
2020 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
TAO-kinase 3 governs the terminal differentiation of NOTCH2-dependent splenic conventional dendritic cells. |
Volume: |
117 |
Issue: |
49 |
Pages: |
31331-31342 |
|
•
•
•
•
•
|
Publication |
First Author: |
Francis R |
Year: |
2019 |
Journal: |
Sci Adv |
Title: |
Gastrointestinal transcription factors drive lineage-specific developmental programs in organ specification and cancer. |
Volume: |
5 |
Issue: |
12 |
Pages: |
eaax8898 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ouadah Y |
Year: |
2019 |
Journal: |
Cell |
Title: |
Rare Pulmonary Neuroendocrine Cells Are Stem Cells Regulated by Rb, p53, and Notch. |
Volume: |
179 |
Issue: |
2 |
Pages: |
403-416.e23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vasquez EG |
Year: |
2022 |
Journal: |
Cell Stem Cell |
Title: |
Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia. |
Volume: |
29 |
Issue: |
8 |
Pages: |
1213-1228.e8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Najumudeen AK |
Year: |
2021 |
Journal: |
Nat Genet |
Title: |
The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer. |
Volume: |
53 |
Issue: |
1 |
Pages: |
16-26 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhu L |
Year: |
2016 |
Journal: |
Cell |
Title: |
Multi-organ Mapping of Cancer Risk. |
Volume: |
166 |
Issue: |
5 |
Pages: |
1132-1146.e7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yu VW |
Year: |
2015 |
Journal: |
J Exp Med |
Title: |
Specific bone cells produce DLL4 to generate thymus-seeding progenitors from bone marrow. |
Volume: |
212 |
Issue: |
5 |
Pages: |
759-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lüdtke TH |
Year: |
2019 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
Mesothelial mobilization in the developing lung and heart differs in timing, quantity, and pathway dependency. |
Volume: |
316 |
Issue: |
5 |
Pages: |
L767-L783 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gillers BS |
Year: |
2015 |
Journal: |
Circ Res |
Title: |
Canonical wnt signaling regulates atrioventricular junction programming and electrophysiological properties. |
Volume: |
116 |
Issue: |
3 |
Pages: |
398-406 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fujimaki S |
Year: |
2022 |
Journal: |
Nat Metab |
Title: |
The endothelial Dll4-muscular Notch2 axis regulates skeletal muscle mass. |
Volume: |
4 |
Issue: |
2 |
Pages: |
180-189 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chang W |
Year: |
2020 |
Journal: |
Cell Stem Cell |
Title: |
Hormonal Suppression of Stem Cells Inhibits Symmetric Cell Division and Gastric Tumorigenesis. |
Volume: |
26 |
Issue: |
5 |
Pages: |
739-754.e8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sakamoto K |
Year: |
2021 |
Journal: |
Immunity |
Title: |
Disruption of the endopeptidase ADAM10-Notch signaling axis leads to skin dysbiosis and innate lymphoid cell-mediated hair follicle destruction. |
Volume: |
54 |
Issue: |
10 |
Pages: |
2321-2337.e10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Baghdadi MB |
Year: |
2018 |
Journal: |
Nature |
Title: |
Reciprocal signalling by Notch-Collagen V-CALCR retains muscle stem cells in their niche. |
Volume: |
557 |
Issue: |
7707 |
Pages: |
714-718 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cheng CW |
Year: |
2019 |
Journal: |
Cell |
Title: |
Ketone Body Signaling Mediates Intestinal Stem Cell Homeostasis and Adaptation to Diet. |
Volume: |
178 |
Issue: |
5 |
Pages: |
1115-1131.e15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Garcia TX |
Year: |
2017 |
Journal: |
Stem Cells Dev |
Title: |
The NOTCH Ligand JAG1 Regulates GDNF Expression in Sertoli Cells. |
Volume: |
26 |
Issue: |
8 |
Pages: |
585-598 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1624
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1214
|
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Houzelstein D |
Year: |
2002 |
Journal: |
Mol Cell Biol |
Title: |
Growth and early postimplantation defects in mice deficient for the bromodomain-containing protein Brd4. |
Volume: |
22 |
Issue: |
11 |
Pages: |
3794-802 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu H |
Year: |
2018 |
Journal: |
J Vasc Res |
Title: |
Evaluation of Notch3 Deficiency in Diabetes-Induced Pericyte Loss in the Retina. |
Volume: |
55 |
Issue: |
5 |
Pages: |
308-318 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jespersen K |
Year: |
2020 |
Journal: |
Sci Rep |
Title: |
Enhanced Notch3 signaling contributes to pulmonary emphysema in a Murine Model of Marfan syndrome. |
Volume: |
10 |
Issue: |
1 |
Pages: |
10949 |
|
•
•
•
•
•
|
Publication |
First Author: |
Neves KB |
Year: |
2019 |
Journal: |
JCI Insight |
Title: |
ER stress and Rho kinase activation underlie the vasculopathy of CADASIL. |
Volume: |
4 |
Issue: |
23 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Ratelade J |
Year: |
2020 |
Journal: |
Circulation |
Title: |
Reducing Hypermuscularization of the Transitional Segment Between Arterioles and Capillaries Protects Against Spontaneous Intracerebral Hemorrhage. |
Volume: |
141 |
Issue: |
25 |
Pages: |
2078-2094 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ling H |
Year: |
2013 |
Journal: |
Cancer Res |
Title: |
Cyclin D1-dependent induction of luminal inflammatory breast tumors by activated notch3. |
Volume: |
73 |
Issue: |
19 |
Pages: |
5963-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Morrison SJ |
Year: |
2002 |
Journal: |
J Immunol |
Title: |
A genetic determinant that specifically regulates the frequency of hematopoietic stem cells. |
Volume: |
168 |
Issue: |
2 |
Pages: |
635-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Daido W |
Year: |
2023 |
Journal: |
Cell Commun Signal |
Title: |
Nestin and Notch3 collaboratively regulate angiogenesis, collagen production, and endothelial-mesenchymal transition in lung endothelial cells. |
Volume: |
21 |
Issue: |
1 |
Pages: |
247 |
|
•
•
•
•
•
|
Publication |
First Author: |
Talora C |
Year: |
2006 |
Journal: |
Blood |
Title: |
Cross talk among Notch3, pre-TCR, and Tal1 in T-cell development and leukemogenesis. |
Volume: |
107 |
Issue: |
8 |
Pages: |
3313-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yu YR |
Year: |
2013 |
Journal: |
Am J Respir Cell Mol Biol |
Title: |
CCR2 deficiency, dysregulation of Notch signaling, and spontaneous pulmonary arterial hypertension. |
Volume: |
48 |
Issue: |
5 |
Pages: |
647-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pekkonen P |
Year: |
2014 |
Journal: |
Cell Cycle |
Title: |
KSHV viral cyclin interferes with T-cell development and induces lymphoma through Cdk6 and Notch activation in vivo. |
Volume: |
13 |
Issue: |
23 |
Pages: |
3670-84 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
128
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
734
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
156
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
305
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1789
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
2473
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Filliol A |
Year: |
2022 |
Journal: |
Nature |
Title: |
Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis. |
Volume: |
610 |
Issue: |
7931 |
Pages: |
356-365 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hayakawa Y |
Year: |
2015 |
Journal: |
Cancer Cell |
Title: |
Mist1 Expressing Gastric Stem Cells Maintain the Normal and Neoplastic Gastric Epithelium and Are Supported by a Perivascular Stem Cell Niche. |
Volume: |
28 |
Issue: |
6 |
Pages: |
800-814 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gu X |
Year: |
2023 |
Journal: |
Nat Commun |
Title: |
Testicular macrophages are recruited during a narrow fetal time window and promote organ-specific developmental functions. |
Volume: |
14 |
Issue: |
1 |
Pages: |
1439 |
|
•
•
•
•
•
|
Publication |
First Author: |
Volckaert T |
Year: |
2011 |
Journal: |
J Clin Invest |
Title: |
Parabronchial smooth muscle constitutes an airway epithelial stem cell niche in the mouse lung after injury. |
Volume: |
121 |
Issue: |
11 |
Pages: |
4409-19 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu WA |
Year: |
2018 |
Journal: |
Genes Dev |
Title: |
PARD3 dysfunction in conjunction with dynamic HIPPO signaling drives cortical enlargement with massive heterotopia. |
Volume: |
32 |
Issue: |
11-12 |
Pages: |
763-780 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yamanaka H |
Year: |
2002 |
Journal: |
Brain Res Gene Expr Patterns |
Title: |
Expression of Apc2 during mouse development. |
Volume: |
1 |
Issue: |
2 |
Pages: |
107-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Checquolo S |
Year: |
2010 |
Journal: |
Oncogene |
Title: |
Differential subcellular localization regulates c-Cbl E3 ligase activity upon Notch3 protein in T-cell leukemia. |
Volume: |
29 |
Issue: |
10 |
Pages: |
1463-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rodriguez S |
Year: |
2008 |
Journal: |
Dev Biol |
Title: |
Notch2 is required for maintaining sustentacular cell function in the adult mouse main olfactory epithelium. |
Volume: |
314 |
Issue: |
1 |
Pages: |
40-58 |
|
•
•
•
•
•
|
Publication |
First Author: |
Baeten JT |
Year: |
2015 |
Journal: |
J Biol Chem |
Title: |
Differential Regulation of NOTCH2 and NOTCH3 Contribute to Their Unique Functions in Vascular Smooth Muscle Cells. |
Volume: |
290 |
Issue: |
26 |
Pages: |
16226-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang M |
Year: |
2015 |
Journal: |
Apoptosis |
Title: |
Notch3/Akt signaling contributes to OSM-induced protection against cardiac ischemia/reperfusion injury. |
Volume: |
20 |
Issue: |
9 |
Pages: |
1150-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Capone C |
Year: |
2016 |
Journal: |
Ann Neurol |
Title: |
Reducing Timp3 or vitronectin ameliorates disease manifestations in CADASIL mice. |
Volume: |
79 |
Issue: |
3 |
Pages: |
387-403 |
|
•
•
•
•
•
|
Publication |
First Author: |
Baron-Menguy C |
Year: |
2017 |
Journal: |
Hypertension |
Title: |
Increased Notch3 Activity Mediates Pathological Changes in Structure of Cerebral Arteries. |
Volume: |
69 |
Issue: |
1 |
Pages: |
60-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lundkvist J |
Year: |
2005 |
Journal: |
Genesis |
Title: |
Mice carrying a R142C Notch 3 knock-in mutation do not develop a CADASIL-like phenotype. |
Volume: |
41 |
Issue: |
1 |
Pages: |
13-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhao N |
Year: |
2015 |
Journal: |
Circ Res |
Title: |
MicroRNA miR145 regulates TGFBR2 expression and matrix synthesis in vascular smooth muscle cells. |
Volume: |
116 |
Issue: |
1 |
Pages: |
23-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Meng H |
Year: |
2010 |
Journal: |
J Biol Chem |
Title: |
Low density lipoprotein receptor-related protein-1 (LRP1) regulates thrombospondin-2 (TSP2) enhancement of Notch3 signaling. |
Volume: |
285 |
Issue: |
30 |
Pages: |
23047-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lindsell CE |
Year: |
1996 |
Journal: |
Mol Cell Neurosci |
Title: |
Expression patterns of Jagged, Delta1, Notch1, Notch2, and Notch3 genes identify ligand-receptor pairs that may function in neural development. |
Volume: |
8 |
Issue: |
1 |
Pages: |
14-27 |
|
•
•
•
•
•
|
Publication |
First Author: |
Brahim S |
Year: |
2023 |
Journal: |
Cell Death Dis |
Title: |
Notch3 regulates Mybl2 via HeyL to limit proliferation and tumor initiation in breast cancer. |
Volume: |
14 |
Issue: |
2 |
Pages: |
171 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vacca A |
Year: |
2006 |
Journal: |
EMBO J |
Title: |
Notch3 and pre-TCR interaction unveils distinct NF-kappaB pathways in T-cell development and leukemia. |
Volume: |
25 |
Issue: |
5 |
Pages: |
1000-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Barbarulo A |
Year: |
2011 |
Journal: |
J Immunol |
Title: |
Notch3 and canonical NF-kappaB signaling pathways cooperatively regulate Foxp3 transcription. |
Volume: |
186 |
Issue: |
11 |
Pages: |
6199-206 |
|
•
•
•
•
•
|
Publication |
First Author: |
Varga J |
Year: |
2020 |
Journal: |
J Exp Med |
Title: |
AKT-dependent NOTCH3 activation drives tumor progression in a model of mesenchymal colorectal cancer. |
Volume: |
217 |
Issue: |
10 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hahn KL |
Year: |
2009 |
Journal: |
Reproduction |
Title: |
A deficiency of lunatic fringe is associated with cystic dilation of the rete testis. |
Volume: |
137 |
Issue: |
1 |
Pages: |
79-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kumar P |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
Soluble OX40L and JAG1 Induce Selective Proliferation of Functional Regulatory T-Cells Independent of canonical TCR signaling. |
Volume: |
7 |
|
Pages: |
39751 |
|
•
•
•
•
•
|
Publication |
First Author: |
Meng H |
Year: |
2009 |
Journal: |
J Biol Chem |
Title: |
Thrombospondin 2 potentiates notch3/jagged1 signaling. |
Volume: |
284 |
Issue: |
12 |
Pages: |
7866-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lardelli M |
Year: |
1996 |
Journal: |
Mech Dev |
Title: |
Expression of the Notch 3 intracellular domain in mouse central nervous system progenitor cells is lethal and leads to disturbed neural tube development. |
Volume: |
59 |
Issue: |
2 |
Pages: |
177-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Carbery ID |
Year: |
2010 |
Journal: |
Genetics |
Title: |
Targeted genome modification in mice using zinc-finger nucleases. |
Volume: |
186 |
Issue: |
2 |
Pages: |
451-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Uyttendaele H |
Year: |
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Dev Cell |
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Title: |
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Gao X |
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Nat Commun |
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The liver-enriched lnc-LFAR1 promotes liver fibrosis by activating TGFβ and Notch pathways. |
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Pontes-Quero S |
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2017 |
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Cell |
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Genome Biol |
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Mol Cell Biol |
Title: |
The Notch signaling pathway controls the size of the ocular lens by directly suppressing p57Kip2 expression. |
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27 |
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J Neurosci |
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Transcriptome analysis for Notch3 target genes identifies Grip2 as a novel regulator of myogenic response in the cerebrovasculature. |
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Dev Cell |
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Villus myofibroblasts are developmental and adult progenitors of mammalian gut lymphatic musculature. |
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PLoS One |
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J Clin Invest |
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JAGGED1/NOTCH3 activation promotes aortic hypermuscularization and stenosis in elastin deficiency. |
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5 |
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Dev Dyn |
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Integral bHLH factor regulation of cell cycle exit and RGC differentiation. |
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