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Search results 1 to 90 out of 90 for Dennd1a

0.028s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Shi J
Year: 2019
Journal: Dev Dyn
Title: Dennd1a, a susceptibility gene for polycystic ovary syndrome, is essential for mouse embryogenesis.
Volume: 248
Issue: 5
Pages: 351-362
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Probe: MGI:7264596
Assay Type: Western blot
Annotation Date: 2022-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:7264622
Age: embryonic day 11.5
Image: 1
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7264596
Assay Type: Western blot
Annotation Date: 2022-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:7264622
Age: embryonic day 11.5
Image: 1
Specimen Label: +/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7264596
Assay Type: Western blot
Annotation Date: 2022-04-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:7264622
Age: embryonic day 11.5
Image: 1
Specimen Label: -/-
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:7264596
Assay Type: Western blot
Annotation Date: 2022-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:7264624
Age: embryonic day 13.5
Image: 1
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7264596
Assay Type: Western blot
Annotation Date: 2022-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:7264624
Age: embryonic day 13.5
Image: 1
Specimen Label: +/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7264596
Assay Type: Western blot
Annotation Date: 2022-04-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:7264624
Age: embryonic day 13.5
Image: 1
Specimen Label: -/-
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:7264611
Assay Type: RT-PCR
Annotation Date: 2022-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:7264634
Age: embryonic day 9.5
Image: 2
Specimen Label: E9.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7264611
Assay Type: RT-PCR
Annotation Date: 2022-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:7264634
Age: embryonic day 10.5
Image: 2
Specimen Label: E10.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:7264606
Assay Type: RNA in situ
Annotation Date: 2022-04-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1640615
Pattern: Widespread
Stage: TS15
Assay Id: MGI:7264630
Age: embryonic day 9.5
Image: 2A
Specimen Label: 2A
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:7264606
Assay Type: RNA in situ
Annotation Date: 2022-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Pattern: Widespread
Stage: TS15
Assay Id: MGI:7264630
Age: embryonic day 9.5
Image: 2A
Specimen Label: 2A
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:7264606
Assay Type: RNA in situ
Annotation Date: 2022-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Pattern: Widespread
Stage: TS17
Assay Id: MGI:7264630
Age: embryonic day 10.5
Image: 2B
Specimen Label: 2B
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:7264606
Assay Type: RNA in situ
Annotation Date: 2022-04-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1664015
Pattern: Widespread
Stage: TS15
Assay Id: MGI:7264630
Age: embryonic day 9.5
Image: 2A
Specimen Label: 2A
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:7264606
Assay Type: RNA in situ
Annotation Date: 2022-04-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1611715
Pattern: Widespread
Stage: TS15
Assay Id: MGI:7264630
Age: embryonic day 9.5
Image: 2A
Specimen Label: 2A
Detected: true
Specimen Num: 1
Publication
First Author: Allaire PD
Year: 2010
Journal: Mol Cell
Title: The Connecdenn DENN domain: a GEF for Rab35 mediating cargo-specific exit from early endosomes.
Volume: 37
Issue: 3
Pages: 370-82
Publication
First Author: Allaire PD
Year: 2006
Journal: J Neurosci
Title: Connecdenn, a novel DENN domain-containing protein of neuronal clathrin-coated vesicles functioning in synaptic vesicle endocytosis.
Volume: 26
Issue: 51
Pages: 13202-12
Protein
Organism: Mus musculus/domesticus
Length: 224  
Fragment?: false
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Allele
Name: DENN domain containing 1A; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Publication
First Author: Marat AL
Year: 2010
Journal: J Biol Chem
Title: The connecdenn family, Rab35 guanine nucleotide exchange factors interfacing with the clathrin machinery.
Volume: 285
Issue: 14
Pages: 10627-37
Protein
Organism: Mus musculus/domesticus
Length: 47  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 61  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 47  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 277  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 413  
Fragment?: false
Protein Domain
Type: Family
Description: This entry includes proteins containing an N-terminal tripartite DENN domain, including DENND1A (also known as connecdenn 1), DENND1B (connecdenn 2) and DENND1C (connecdenn 3). These proteins act as guanine-nucleotide exchange factors for Rab35 through the DENN domain. Inactive GDP-bound RAB35 is converted into its active GTP-bound form by the exchange of GDP to GTP. The DENN domains of DENND1A and DENND1B, but not DENND1C, bind Rab35, indicating that binding and activation are separate. The C-termini of DENND1A, DENND1B and DENND1C differ significantly, but each binds to clathrin and to the clathrin adaptor AP-2. This is a means to regulate clathrin-mediated endocytosis of synaptic vesicles and exit from early endosomes [].
Protein
Organism: Mus musculus/domesticus
Length: 103  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 105  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 845  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1016  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 766  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 786  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 352  
Fragment?: false
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7