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Search results 1 to 100 out of 111 for Pla2g6

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Category: Publication
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Type Details Score
Publication
33087576 | J:297121
First Author: Beharier O
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: PLA2G6 guards placental trophoblasts against ferroptotic injury.
Volume: 117
Issue: 44
Pages: 27319-27328
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Publication
28655161 | J:319256
First Author: Li M
Year: 2017
Journal: J Mol Cell Biol
Title: Dysfunction of PLA2G6 and CYP2C44-associated network signals imminent carcinogenesis from chronic inflammation to hepatocellular carcinoma.
Volume: 9
Issue: 6
Pages: 489-503
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Publication
22046428 | J:179704
First Author: Zhao Z
Year: 2011
Journal: PLoS One
Title: Genetic ablation of PLA2G6 in mice leads to cerebellar atrophy characterized by Purkinje cell loss and glial cell activation.
Volume: 6
Issue: 10
Pages: e26991
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Publication
25337551 | J:203038
First Author: Zhang L
Year: 2013
Journal: J Cancer Prev
Title: Global Inactivation of the Pla2g6 Gene in Mice Does Not Cause Dyslipidemia under Chow or High-fat Diet Conditions.
Volume: 18
Issue: 3
Pages: 235-48
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Publication
- | J:153195
 
First Author: Watabe K
Year: 2008
Journal: Neuropathology
Title: A mouse model for infantile neuroaxonal dystrophy with PLA2G6 mutation generated by ENU-mutagenesis
Volume: 28
Pages: 184 (O-1-A11 Abstr.)
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Publication
18202189 | J:131429
First Author: Malik I
Year: 2008
Journal: Am J Pathol
Title: Disrupted membrane homeostasis and accumulation of ubiquitinated proteins in a mouse model of infantile neuroaxonal dystrophy caused by PLA2G6 mutations.
Volume: 172
Issue: 2
Pages: 406-16
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Publication
30088174 | J:317126
First Author: Chiu CC
Year: 2019
Journal: Mol Neurobiol
Title: PARK14 (D331Y) PLA2G6 Causes Early-Onset Degeneration of Substantia Nigra Dopaminergic Neurons by Inducing Mitochondrial Dysfunction, ER Stress, Mitophagy Impairment and Transcriptional Dysregulation in a Knockin Mouse Model.
Volume: 56
Issue: 6
Pages: 3835-3853
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Publication
21813701 | J:174587
First Author: Beck G
Year: 2011
Journal: J Neurosci
Title: Neuroaxonal dystrophy in calcium-independent phospholipase A2β deficiency results from insufficient remodeling and degeneration of mitochondrial and presynaptic membranes.
Volume: 31
Issue: 31
Pages: 11411-20
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Publication
27078024 | J:249141
First Author: Beck G
Year: 2016
Journal: PLoS One
Title: Progressive Axonal Degeneration of Nigrostriatal Dopaminergic Neurons in Calcium-Independent Phospholipase A2β Knockout Mice.
Volume: 11
Issue: 4
Pages: e0153789
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Publication
19893029 | J:155328
First Author: Wada H
Year: 2009
Journal: Am J Pathol
Title: Establishment of an improved mouse model for infantile neuroaxonal dystrophy that shows early disease onset and bears a point mutation in Pla2g6.
Volume: 175
Issue: 6
Pages: 2257-63
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Publication
22442204 | J:183152
First Author: Strokin M
Year: 2012
Journal: Hum Mol Genet
Title: Severe disturbance in the Ca2+ signaling in astrocytes from mouse models of human infantile neuroaxonal dystrophy with mutated Pla2g6.
Volume: 21
Issue: 12
Pages: 2807-14
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Publication
22349267 | J:188097
First Author: Cheon Y
Year: 2012
Journal: Biochim Biophys Acta
Title: Disturbed brain phospholipid and docosahexaenoic acid metabolism in calcium-independent phospholipase A(2)-VIA (iPLA(2)β)-knockout mice.
Volume: 1821
Issue: 9
Pages: 1278-86
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Publication
36334837 | J:331723
First Author: Jansakun C
Year: 2023
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Myeloid- and hepatocyte-specific deletion of group VIA calcium-independent phospholipase A2 leads to dichotomous opposing phenotypes during MCD diet-induced NASH.
Volume: 1869
Issue: 1
Pages: 166590
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Publication
26873633 | J:251600
First Author: Deng X
Year: 2016
Journal: Biochim Biophys Acta
Title: iPLA2β deficiency attenuates obesity and hepatic steatosis in ob/ob mice through hepatic fatty-acyl phospholipid remodeling.
Volume: 1861
Issue: 5
Pages: 449-61
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Publication
38198970 | J:346451
First Author: Klement L
Year: 2024
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Myeloid-specific deletion of group VIA calcium-independent phospholipase A2 induces pro-inflammatory LPS response predominantly in male mice via MIP-1α activation.
Volume: 1870
Issue: 3
Pages: 167016
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Publication
9079688 | J:62053
First Author: Balboa MA
Year: 1997
Journal: J Biol Chem
Title: Identity between the Ca2+-independent phospholipase A2 enzymes from P388D1 macrophages and Chinese hamster ovary cells.
Volume: 272
Issue: 13
Pages: 8576-80
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Publication
17895289 | J:133472
First Author: Bao S
Year: 2008
Journal: Am J Physiol Endocrinol Metab
Title: Glucose homeostasis, insulin secretion, and islet phospholipids in mice that overexpress iPLA2beta in pancreatic beta-cells and in iPLA2beta-null mice.
Volume: 294
Issue: 2
Pages: E217-29
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Publication
18937505 | J:144546
First Author: Carper MJ
Year: 2008
Journal: Biochemistry
Title: Skeletal muscle group VIA phospholipase A2 (iPLA2beta): expression and role in fatty acid oxidation.
Volume: 47
Issue: 46
Pages: 12241-9
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Publication
18305254 | J:132853
First Author: Shinzawa K
Year: 2008
Journal: J Neurosci
Title: Neuroaxonal dystrophy caused by group VIA phospholipase A2 deficiency in mice: a model of human neurodegenerative disease.
Volume: 28
Issue: 9
Pages: 2212-20
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Publication
32818532 | J:300778
 
First Author: Minkley M
Year: 2020
Journal: Brain Res
Title: Loss of tyrosine hydroxylase, motor deficits and elevated iron in a mouse model of phospholipase A2G6-associated neurodegeneration (PLAN).
Volume: 1748
Pages: 147066
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Publication
2888882 | J:243703
 
First Author: Kelly SS
Year: 1987
Journal: J Physiol
Title: Statistics of neuromuscular transmitter release in young and old mouse muscle.
Volume: 385
Pages: 507-16
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20521843 | J:164527
First Author: Sharma J
Year: 2010
Journal: Biochemistry
Title: Endothelial cell prostaglandin I(2) and platelet-activating factor production are markedly attenuated in the calcium-independent phospholipase A(2)beta knockout mouse.
Volume: 49
Issue: 26
Pages: 5473-81
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Publication
30735854 | J:274325
First Author: Zhu X
Year: 2019
Journal: Biochim Biophys Acta Mol Cell Biol Lipids
Title: iPla2β deficiency in mice fed with MCD diet does not correct the defect of phospholipid remodeling but attenuates hepatocellular injury via an inhibition of lipid uptake genes.
Volume: 1864
Issue: 5
Pages: 677-687
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Publication
30735855 | J:274361
First Author: Otto AC
Year: 2019
Journal: Biochim Biophys Acta Mol Cell Biol Lipids
Title: Group VIA phospholipase A2 deficiency in mice chronically fed with high-fat-diet attenuates hepatic steatosis by correcting a defect of phospholipid remodeling.
Volume: 1864
Issue: 5
Pages: 662-676
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Publication
20382858 | J:160339
First Author: Dietrich HH
Year: 2010
Journal: Am J Physiol Heart Circ Physiol
Title: Genetic ablation of calcium-independent phospholipase A(2)beta causes hypercontractility and markedly attenuates endothelium-dependent relaxation to acetylcholine.
Volume: 298
Issue: 6
Pages: H2208-20
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Publication
20530749 | J:165310
First Author: Li H
Year: 2010
Journal: FASEB J
Title: Group VIA phospholipase A2 in both host and tumor cells is involved in ovarian cancer development.
Volume: 24
Issue: 10
Pages: 4103-16
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Publication
24791136 | J:212319
 
First Author: Kolko M
Year: 2014
Journal: Mol Vis
Title: Calcium-independent phospholipase A₂, group VIA, is critical for RPE cell survival.
Volume: 20
Pages: 511-21
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31409057 | J:293445
 
First Author: Ming Y
Year: 2019
Journal: Cells
Title: iPla2β Deficiency Suppresses Hepatic ER UPR, Fxr, and Phospholipids in Mice Fed with MCD Diet, Resulting in Exacerbated Hepatic Bile Acids and Biliary Cell Proliferation.
Volume: 8
Issue: 8
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28888832 | J:256253
First Author: Jiao L
Year: 2017
Journal: Biochim Biophys Acta
Title: Ageing sensitized by iPLA2β deficiency induces liver fibrosis and intestinal atrophy involving suppression of homeostatic genes and alteration of intestinal lipids and bile acids.
Volume: 1862
Issue: 12
Pages: 1520-1533
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Publication
36430237 | J:332121
 
First Author: Andrade A
Year: 2022
Journal: Int J Mol Sci
Title: iPLA2β-Null Mice Show HCC Protection by an Induction of Cell-Cycle Arrest after Diethylnitrosamine Treatment.
Volume: 23
Issue: 22
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20463052 | J:162931
First Author: Zhao Z
Year: 2010
Journal: Endocrinology
Title: Protection of pancreatic beta-cells by group VIA phospholipase A(2)-mediated repair of mitochondrial membrane peroxidation.
Volume: 151
Issue: 7
Pages: 3038-48
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18927078 | J:144575
First Author: Moon SH
Year: 2008
Journal: J Biol Chem
Title: Smooth muscle cell arachidonic acid release, migration, and proliferation are markedly attenuated in mice null for calcium-independent phospholipase A2beta.
Volume: 283
Issue: 49
Pages: 33975-87
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21228317 | J:171156
First Author: McHowat J
Year: 2011
Journal: Am J Physiol Cell Physiol
Title: Platelet-activating factor and metastasis: calcium-independent phospholipase A2β deficiency protects against breast cancer metastasis to the lung.
Volume: 300
Issue: 4
Pages: C825-32
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25957555 | J:251248
First Author: Jiao L
Year: 2015
Journal: Biochim Biophys Acta
Title: Sensitization to autoimmune hepatitis in group VIA calcium-independent phospholipase A2-null mice led to duodenal villous atrophy with apoptosis, goblet cell hyperplasia and leaked bile acids.
Volume: 1852
Issue: 8
Pages: 1646-57
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18349124 | J:133346
First Author: Ramanadham S
Year: 2008
Journal: Am J Pathol
Title: Age-related changes in bone morphology are accelerated in group VIA phospholipase A2 (iPLA2beta)-null mice.
Volume: 172
Issue: 4
Pages: 868-81
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16732058 | J:116477
First Author: Bao S
Year: 2006
Journal: J Biol Chem
Title: Insulin secretory responses and phospholipid composition of pancreatic islets from mice that do not express Group VIA phospholipase A2 and effects of metabolic stress on glucose homeostasis.
Volume: 281
Issue: 30
Pages: 20958-73
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17627946 | J:172112
First Author: Bao S
Year: 2007
Journal: J Biol Chem
Title: Attenuated free cholesterol loading-induced apoptosis but preserved phospholipid composition of peritoneal macrophages from mice that do not express group VIA phospholipase A2.
Volume: 282
Issue: 37
Pages: 27100-14
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27650501 | J:237346
First Author: Ashley JW
Year: 2016
Journal: J Biol Chem
Title: Polarization of Macrophages toward M2 Phenotype Is Favored by Reduction in iPLA2β (Group VIA Phospholipase A2).
Volume: 291
Issue: 44
Pages: 23268-23281
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21984569 | J:183334
First Author: Sharma J
Year: 2012
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Lung endothelial cell platelet-activating factor production and inflammatory cell adherence are increased in response to cigarette smoke component exposure.
Volume: 302
Issue: 1
Pages: L47-55
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25004092 | J:218128
First Author: Lei X
Year: 2014
Journal: Endocrinology
Title: Evidence of contribution of iPLA2β-mediated events during islet β-cell apoptosis due to proinflammatory cytokines suggests a role for iPLA2β in T1D development.
Volume: 155
Issue: 9
Pages: 3352-64
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15252026 | J:92835
First Author: Bao S
Year: 2004
Journal: J Biol Chem
Title: Male mice that do not express group VIA phospholipase A2 produce spermatozoa with impaired motility and have greatly reduced fertility.
Volume: 279
Issue: 37
Pages: 38194-200
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9361012 | J:44049
First Author: Balsinde J
Year: 1997
Journal: J Biol Chem
Title: Antisense inhibition of group VI Ca2+-independent phospholipase A2 blocks phospholipid fatty acid remodeling in murine P388D1 macrophages.
Volume: 272
Issue: 46
Pages: 29317-21
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16926189 | J:113111
First Author: Boittin FX
Year: 2006
Journal: J Cell Sci
Title: Ca2+-independent phospholipase A2 enhances store-operated Ca2+ entry in dystrophic skeletal muscle fibers.
Volume: 119
Issue: Pt 18
Pages: 3733-42
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19914213 | J:156728
First Author: Boittin FX
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Phospholipase A2-derived lysophosphatidylcholine triggers Ca2+ entry in dystrophic skeletal muscle fibers.
Volume: 391
Issue: 1
Pages: 401-6
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26755131 | J:235888
 
First Author: Zhou Q
Year: 2016
Journal: Nat Commun
Title: Impairment of PARK14-dependent Ca(2+) signalling is a novel determinant of Parkinson's disease.
Volume: 7
Pages: 10332
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27789386 | J:238208
 
First Author: Chew WS
Year: 2017
Journal: Neuroscience
Title: Role of prefrontal cortical calcium-independent phospholipase A2 in antinociceptive effect of the norepinephrine reuptake inhibitor antidepresssant maprotiline.
Volume: 340
Pages: 91-100
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25213337 | J:246157
First Author: Bone RN
Year: 2015
Journal: Diabetes
Title: Inhibition of Ca2+-independent phospholipase A2β (iPLA2β) ameliorates islet infiltration and incidence of diabetes in NOD mice.
Volume: 64
Issue: 2
Pages: 541-54
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21191104 | J:171167
First Author: Sharma J
Year: 2011
Journal: Am J Physiol Cell Physiol
Title: Activation of group VI phospholipase A2 isoforms in cardiac endothelial cells.
Volume: 300
Issue: 4
Pages: C872-9
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22389508 | J:184885
First Author: Moon SH
Year: 2012
Journal: J Biol Chem
Title: Activation of mitochondrial calcium-independent phospholipase A2γ (iPLA2γ) by divalent cations mediating arachidonate release and production of downstream eicosanoids.
Volume: 287
Issue: 18
Pages: 14880-95
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26206229 | J:226333
First Author: Rauckhorst AJ
Year: 2015
Journal: FEBS Lett
Title: The iPLA(2)γ is identified as the membrane potential sensitive phospholipase in liver mitochondria.
Volume: 589
Issue: 18
Pages: 2367-71
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22778252 | J:190421
First Author: Moon SH
Year: 2012
Journal: J Biol Chem
Title: Genetic ablation of calcium-independent phospholipase A(2)γ (iPLA(2)γ) attenuates calcium-induced opening of the mitochondrial permeability transition pore and resultant cytochrome c release.
Volume: 287
Issue: 35
Pages: 29837-50
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27226532 | J:235458
First Author: Elimam H
Year: 2016
Journal: J Biol Chem
Title: Genetic Ablation of Calcium-independent Phospholipase A2γ Induces Glomerular Injury in Mice.
Volume: 291
Issue: 28
Pages: 14468-82
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35796562 | J:332444
First Author: Murray GC
Year: 2022
Journal: Hum Mol Genet
Title: Mouse models of NADK2 deficiency analyzed for metabolic and gene expression changes to elucidate pathophysiology.
Volume: 31
Issue: 23
Pages: 4055-4074
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17613534 | J:124654
First Author: Xie Z
Year: 2007
Journal: J Biol Chem
Title: Group VIA phospholipase A2 (iPLA2beta) participates in angiotensin II-induced transcriptional up-regulation of regulator of g-protein signaling-2 in vascular smooth muscle cells.
Volume: 282
Issue: 35
Pages: 25278-89
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33080873 | J:299007
 
First Author: Turk J
Year: 2020
Journal: Biomolecules
Title: Metabolic Effects of Selective Deletion of Group VIA Phospholipase A2 from Macrophages or Pancreatic Islet Beta-Cells.
Volume: 10
Issue: 10
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18208975 | J:131740
First Author: Mishra RS
Year: 2008
Journal: J Exp Med
Title: iPLA2beta: front and center in human monocyte chemotaxis to MCP-1.
Volume: 205
Issue: 2
Pages: 347-59
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22218592 | J:182432
First Author: Paliege A
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Group VIA phospholipase A2 is a target for vasopressin signaling in the thick ascending limb.
Volume: 302
Issue: 7
Pages: F865-74
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33177235 | J:300067
First Author: Akhade AS
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Type 1 interferon-dependent repression of NLRC4 and iPLA2 licenses down-regulation of Salmonella flagellin inside macrophages.
Volume: 117
Issue: 47
Pages: 29811-29822
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23124680 | J:330445
First Author: Kanno Y
Year: 2013
Journal: Arthritis Rheum
Title: Alpha2-antiplasmin regulates the development of dermal fibrosis in mice by prostaglandin F(2α) synthesis through adipose triglyceride lipase/calcium-independent phospholipase A(2).
Volume: 65
Issue: 2
Pages: 492-502
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24858037 | J:217025
First Author: Yun HM
Year: 2014
Journal: Oncogene
Title: Loss of presenilin 2 is associated with increased iPLA2 activity and lung tumor development.
Volume: 33
Issue: 44
Pages: 5193-200
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22637477 | J:188859
First Author: Liu S
Year: 2012
Journal: J Biol Chem
Title: Smooth muscle-specific expression of calcium-independent phospholipase A2β (iPLA2β) participates in the initiation and early progression of vascular inflammation and neointima formation.
Volume: 287
Issue: 29
Pages: 24739-53
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22194610 | J:182443
First Author: Song H
Year: 2012
Journal: J Biol Chem
Title: Group VIA PLA2 (iPLA2β) is activated upstream of p38 mitogen-activated protein kinase (MAPK) in pancreatic islet β-cell signaling.
Volume: 287
Issue: 8
Pages: 5528-41
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22094335 | J:183316
First Author: Yang B
Year: 2012
Journal: Am J Physiol Cell Physiol
Title: Orai1 and Ca2+-independent phospholipase A2 are required for store-operated Icat-SOC current, Ca2+ entry, and proliferation of primary vascular smooth muscle cells.
Volume: 302
Issue: 5
Pages: C748-56
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36719796 | J:333442
First Author: Hirabayashi T
Year: 2023
Journal: Cell Rep
Title: Hepatic phosphatidylcholine catabolism driven by PNPLA7 and PNPLA8 supplies endogenous choline to replenish the methionine cycle with methyl groups.
Volume: 42
Issue: 2
Pages: 111940
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26655718 | J:230928
First Author: Abi Nahed R
Year: 2016
Journal: J Biol Chem
Title: Progesterone-induced Acrosome Exocytosis Requires Sequential Involvement of Calcium-independent Phospholipase A2β (iPLA2β) and Group X Secreted Phospholipase A2 (sPLA2).
Volume: 291
Issue: 6
Pages: 3076-89
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31019507 | J:336884
 
First Author: Zakrzewicz A
Year: 2019
Journal: Front Immunol
Title: SLPI Inhibits ATP-Mediated Maturation of IL-1β in Human Monocytic Leukocytes: A Novel Function of an Old Player.
Volume: 10
Pages: 664
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16818490 | J:116945
First Author: Simon GM
Year: 2006
Journal: J Biol Chem
Title: Endocannabinoid biosynthesis proceeding through glycerophospho-N-acyl ethanolamine and a role for alpha/beta-hydrolase 4 in this pathway.
Volume: 281
Issue: 36
Pages: 26465-72
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21880721 | J:177565
First Author: Ueno N
Year: 2011
Journal: J Biol Chem
Title: Analysis of two major intracellular phospholipases A(2) (PLA(2)) in mast cells reveals crucial contribution of cytosolic PLA(2)α, not Ca(2+)-independent PLA(2)β, to lipid mobilization in proximal mast cells and distal fibroblasts.
Volume: 286
Issue: 43
Pages: 37249-63
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31337982 | J:290630
First Author: Li J
Year: 2019
Journal: Int J Biol Sci
Title: Amorphous solid dispersion of Berberine mitigates apoptosis via iPLA2β/Cardiolipin/Opa1 pathway in db/db mice and in Palmitate-treated MIN6 β-cells.
Volume: 15
Issue: 7
Pages: 1533-1545
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19917703 | J:157509
First Author: Lee SH
Year: 2009
Journal: J Immunol
Title: Calcium-independent phospholipase A2beta-Akt signaling is involved in lipopolysaccharide-induced NADPH oxidase 1 expression and foam cell formation.
Volume: 183
Issue: 11
Pages: 7497-504
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17873277 | J:128345
First Author: Nikolic DM
Year: 2007
Journal: J Biol Chem
Title: Class A scavenger receptor-mediated macrophage adhesion requires coupling of calcium-independent phospholipase A(2) and 12/15-lipoxygenase to Rac and Cdc42 activation.
Volume: 282
Issue: 46
Pages: 33405-11
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26828067 | J:232433
First Author: Murase R
Year: 2016
Journal: J Biol Chem
Title: Group X Secreted Phospholipase A2 Releases ω3 Polyunsaturated Fatty Acids, Suppresses Colitis, and Promotes Sperm Fertility.
Volume: 291
Issue: 13
Pages: 6895-911
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- | J:90559
     
First Author: The Mammalian Genetics Unit at Harwell
Year: 2004
Journal: Unpublished
Title: Information obtained from the Mammalian Genetics Unit, Medical Research Council (MRC), Harwell, UK
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- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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- | J:82809
     
First Author: European Mouse Mutant Archive
Year: 2003
Journal: Unpublished
Title: Information obtained from the European Mouse Mutant Archive (EMMA)
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- | J:101977
     
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
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- | J:165964
     
First Author: Mammalian Functional Genomics Centre
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the NorCOMM project by the Mammalian Functional Genomics Centre (Mfgc), University of Manitoba
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- | J:72245
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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