Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry represents lysine-specific demethylase 6B (also known as JMJD3 or KDM6B). UTX (also known as KDM6A), JMJD3 (also known as KDM6B) and UTY (also known as KDM6C) are the members of the JmjC (Jumonji C) subfamily of the histone lysine demethylases family (KDM). They are histone demethylases that catalyse demethylation of H3K27, a mark important for transcriptional repression []. Unlike KDM6A, KDM6B is highly regulated at the transcriptional level and is upregulated in response to oncogenic stress [, ]. It is recruited to p53 bound promoters and enhancer elements in a p53 dependent manner []. It also plays important roles in osteoblast differentiation and regulates the expressions of bone sialoprotein and osteocalcin via transcription factors Runx2 and osterix []. Its subcellular localisation is dynamically regulated and has pivotal roles for H3K27me3 status []. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Agger K |
Year: |
2009 |
Journal: |
Genes Dev |
Title: |
The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence. |
Volume: |
23 |
Issue: |
10 |
Pages: |
1171-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Goswami S |
Year: |
2023 |
Journal: |
Nat Cancer |
Title: |
Myeloid-specific KDM6B inhibition sensitizes glioblastoma to PD1 blockade. |
Volume: |
4 |
Issue: |
10 |
Pages: |
1455-1473 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mallaney C |
Year: |
2019 |
Journal: |
Leukemia |
Title: |
Kdm6b regulates context-dependent hematopoietic stem cell self-renewal and leukemogenesis. |
Volume: |
33 |
Issue: |
10 |
Pages: |
2506-2521 |
|
•
•
•
•
•
|
Publication |
First Author: |
Brauer B |
Year: |
2024 |
Journal: |
Sci Rep |
Title: |
Impact of KDM6B mosaic brain knockout on synaptic function and behavior. |
Volume: |
14 |
Issue: |
1 |
Pages: |
20416 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wei Y |
Year: |
2018 |
Journal: |
Blood Adv |
Title: |
KDM6B overexpression activates innate immune signaling and impairs hematopoiesis in mice. |
Volume: |
2 |
Issue: |
19 |
Pages: |
2491-2504 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xu T |
Year: |
2021 |
Journal: |
J Immunol |
Title: |
Kdm6b Regulates the Generation of Effector CD8+ T Cells by Inducing Chromatin Accessibility in Effector-Associated Genes. |
Volume: |
206 |
Issue: |
9 |
Pages: |
2170-2183 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wijayatunge R |
Year: |
2014 |
Journal: |
Mol Cell Neurosci |
Title: |
The histone lysine demethylase Kdm6b is required for activity-dependent preconditioning of hippocampal neuronal survival. |
Volume: |
61 |
|
Pages: |
187-200 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang L |
Year: |
2018 |
Journal: |
EMBO Rep |
Title: |
KDM6A and KDM6B play contrasting roles in nuclear transfer embryos revealed by MERVL reporter system. |
Volume: |
19 |
Issue: |
12 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Guo T |
Year: |
2022 |
Journal: |
Elife |
Title: |
KDM6B interacts with TFDP1 to activate P53 signaling in regulating mouse palatogenesis. |
Volume: |
11 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wijayatunge R |
Year: |
2018 |
Journal: |
Mol Cell Neurosci |
Title: |
The histone demethylase Kdm6b regulates a mature gene expression program in differentiating cerebellar granule neurons. |
Volume: |
87 |
|
Pages: |
4-17 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wei Y |
Year: |
2022 |
Journal: |
Leukemia |
Title: |
Cooperation between KDM6B overexpression and TET2 deficiency in the pathogenesis of chronic myelomonocytic leukemia. |
Volume: |
36 |
Issue: |
8 |
Pages: |
2097-2107 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang W |
Year: |
2022 |
Journal: |
Nat Commun |
Title: |
The histone demethylase Kdm6b regulates subtype diversification of mouse spinal motor neurons during development. |
Volume: |
13 |
Issue: |
1 |
Pages: |
958 |
|
•
•
•
•
•
|
Publication |
First Author: |
Saha B |
Year: |
2013 |
Journal: |
Mol Cell Biol |
Title: |
EED and KDM6B coordinate the first mammalian cell lineage commitment to ensure embryo implantation. |
Volume: |
33 |
Issue: |
14 |
Pages: |
2691-705 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
142
|
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Walport LJ |
Year: |
2014 |
Journal: |
J Biol Chem |
Title: |
Human UTY(KDM6C) is a male-specific Nϵ-methyl lysyl demethylase. |
Volume: |
289 |
Issue: |
26 |
Pages: |
18302-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Williams K |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
The histone lysine demethylase JMJD3/KDM6B is recruited to p53 bound promoters and enhancer elements in a p53 dependent manner. |
Volume: |
9 |
Issue: |
5 |
Pages: |
e96545 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang D |
Year: |
2013 |
Journal: |
J Biol Chem |
Title: |
Histone demethylase Jmjd3 regulates osteoblast differentiation via transcription factors Runx2 and osterix. |
Volume: |
288 |
Issue: |
47 |
Pages: |
33530-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kamikawa YF |
Year: |
2014 |
Journal: |
Epigenetics |
Title: |
The localization of histone H3K27me3 demethylase Jmjd3 is dynamically regulated. |
Volume: |
9 |
Issue: |
6 |
Pages: |
834-41 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1641
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Umutoni D |
Year: |
2020 |
Journal: |
Genes Cells |
Title: |
H3K27me3 demethylase UTX regulates the differentiation of a subset of bipolar cells in the mouse retina. |
Volume: |
25 |
Issue: |
6 |
Pages: |
402-412 |
|
•
•
•
•
•
|
Publication |
First Author: |
Iwagawa T |
Year: |
2020 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Jmjd3 Plays Pivotal Roles in the Proper Development of Early-Born Retinal Lineages: Amacrine, Horizontal, and Retinal Ganglion Cells. |
Volume: |
61 |
Issue: |
11 |
Pages: |
43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tian L |
Year: |
2017 |
Journal: |
Gene |
Title: |
miR-148a-3p regulates adipocyte and osteoblast differentiation by targeting lysine-specific demethylase 6b. |
Volume: |
627 |
|
Pages: |
32-39 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yu XX |
Year: |
2018 |
Journal: |
Development |
Title: |
Dynamics of chromatin marks and the role of JMJD3 during pancreatic endocrine cell fate commitment. |
Volume: |
145 |
Issue: |
6 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Ge G |
Year: |
2024 |
Journal: |
J Clin Invest |
Title: |
Targeting lysine demethylase 6B ameliorates ASXL1 truncation-mediated myeloid malignancies in preclinical models. |
Volume: |
134 |
Issue: |
1 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wu Q |
Year: |
2022 |
Journal: |
Nat Commun |
Title: |
Selective translation of epigenetic modifiers affects the temporal pattern and differentiation of neural stem cells. |
Volume: |
13 |
Issue: |
1 |
Pages: |
470 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hofstetter C |
Year: |
2016 |
Journal: |
J Cell Sci |
Title: |
Inhibition of KDM6 activity during murine ESC differentiation induces DNA damage. |
Volume: |
129 |
Issue: |
4 |
Pages: |
788-803 |
|
•
•
•
•
•
|
Publication |
First Author: |
Duong P |
Year: |
2021 |
Journal: |
J Biol Chem |
Title: |
H3K27 demethylases are dispensable for activation of Polycomb-regulated injury response genes in peripheral nerve. |
Volume: |
297 |
Issue: |
1 |
Pages: |
100852 |
|
•
•
•
•
•
|
Publication |
First Author: |
Noda H |
Year: |
2023 |
Journal: |
Cancer Sci |
Title: |
The histone demethylase Utx controls CD8(+) T-cell-dependent antitumor immunity via epigenetic regulation of the effector function. |
Volume: |
114 |
Issue: |
7 |
Pages: |
2787-2797 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fei T |
Year: |
2010 |
Journal: |
Genome Res |
Title: |
Genome-wide mapping of SMAD target genes reveals the role of BMP signaling in embryonic stem cell fate determination. |
Volume: |
20 |
Issue: |
1 |
Pages: |
36-44 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Ramesh V |
Year: |
2023 |
Journal: |
Elife |
Title: |
Bidirectional regulation of postmitotic H3K27me3 distributions underlie cerebellar granule neuron maturation dynamics. |
Volume: |
12 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Li Q |
Year: |
2014 |
Journal: |
Nat Commun |
Title: |
Critical role of histone demethylase Jmjd3 in the regulation of CD4+ T-cell differentiation. |
Volume: |
5 |
|
Pages: |
5780 |
|
•
•
•
•
•
|
Publication |
First Author: |
Song A |
Year: |
2017 |
Journal: |
Endocrinology |
Title: |
JMJD3 Is Crucial for the Female AVPV RIP-Cre Neuron-Controlled Kisspeptin-Estrogen Feedback Loop and Reproductive Function. |
Volume: |
158 |
Issue: |
6 |
Pages: |
1798-1811 |
|
•
•
•
•
•
|
Publication |
First Author: |
Iwamori N |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
H3K27 demethylase, JMJD3, regulates fragmentation of spermatogonial cysts. |
Volume: |
8 |
Issue: |
8 |
Pages: |
e72689 |
|
•
•
•
•
•
|
Publication |
First Author: |
De Santa F |
Year: |
2009 |
Journal: |
EMBO J |
Title: |
Jmjd3 contributes to the control of gene expression in LPS-activated macrophages. |
Volume: |
28 |
Issue: |
21 |
Pages: |
3341-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang H |
Year: |
2018 |
Journal: |
Exp Neurol |
Title: |
Inhibiting Jumoji domain containing protein 3 (JMJD3) prevent neuronal apoptosis from stroke. |
Volume: |
308 |
|
Pages: |
132-142 |
|
•
•
•
•
•
|
Publication |
First Author: |
Burgold T |
Year: |
2008 |
Journal: |
PLoS One |
Title: |
The histone H3 lysine 27-specific demethylase Jmjd3 is required for neural commitment. |
Volume: |
3 |
Issue: |
8 |
Pages: |
e3034 |
|
•
•
•
•
•
|
Publication |
First Author: |
Barradas M |
Year: |
2009 |
Journal: |
Genes Dev |
Title: |
Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS. |
Volume: |
23 |
Issue: |
10 |
Pages: |
1177-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee K |
Year: |
2012 |
Journal: |
J Neurochem |
Title: |
Molecular mechanism of Jmjd3-mediated interleukin-6 gene regulation in endothelial cells underlying spinal cord injury. |
Volume: |
122 |
Issue: |
2 |
Pages: |
272-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jia W |
Year: |
2018 |
Journal: |
FASEB J |
Title: |
Histone demethylase JMJD3 regulates fibroblast-like synoviocyte-mediated proliferation and joint destruction in rheumatoid arthritis. |
Volume: |
32 |
Issue: |
7 |
Pages: |
4031-4042 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jin M |
Year: |
2019 |
Journal: |
J Cell Mol Med |
Title: |
Leonurine suppresses neuroinflammation through promoting oligodendrocyte maturation. |
Volume: |
23 |
Issue: |
2 |
Pages: |
1470-1485 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huang M |
Year: |
2020 |
Journal: |
FASEB J |
Title: |
Jmjd3 regulates inflammasome activation and aggravates DSS-induced colitis in mice. |
Volume: |
34 |
Issue: |
3 |
Pages: |
4107-4119 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6403138 |
Assay Type: |
RT-PCR |
Annotation Date: |
2020-04-07 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691624 |
|
Stage: |
TS24 |
Assay Id: |
MGI:6403155 |
Age: |
embryonic day 16.5 |
Image: |
1 |
|
Specimen Label: |
Jmjd3+/+ hindbrain |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6403138 |
Assay Type: |
RT-PCR |
Annotation Date: |
2020-04-07 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691624 |
|
Stage: |
TS24 |
Assay Id: |
MGI:6403155 |
Age: |
embryonic day 16.5 |
Image: |
1 |
|
Specimen Label: |
Jmjd3-/- hindbrain |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6403138 |
Assay Type: |
RT-PCR |
Annotation Date: |
2020-04-07 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689524 |
|
Stage: |
TS24 |
Assay Id: |
MGI:6403155 |
Age: |
embryonic day 16.5 |
Image: |
1 |
|
Specimen Label: |
Jmjd3+/+ forebrain |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6403138 |
Assay Type: |
RT-PCR |
Annotation Date: |
2020-04-07 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689524 |
|
Stage: |
TS24 |
Assay Id: |
MGI:6403155 |
Age: |
embryonic day 16.5 |
Image: |
1 |
|
Specimen Label: |
Jmjd3-/- forebrain |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6403904 |
Assay Type: |
RT-PCR |
Annotation Date: |
2020-04-15 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1778724 |
|
Stage: |
TS24 |
Assay Id: |
MGI:6403950 |
Age: |
embryonic day 16.5 |
Image: |
5 |
|
Specimen Label: |
E16.5 CB |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6403904 |
Assay Type: |
RT-PCR |
Annotation Date: |
2020-04-15 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1778728 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6403950 |
Age: |
postnatal day 4 |
Image: |
5 |
|
Specimen Label: |
P4 CB |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6403904 |
Assay Type: |
RT-PCR |
Annotation Date: |
2020-04-15 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1778728 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6403950 |
Age: |
postnatal day 50 |
Image: |
5 |
|
Specimen Label: |
P50 CB |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7366953 |
Assay Type: |
Western blot |
Annotation Date: |
2022-10-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1736221 |
|
Stage: |
TS21 |
Assay Id: |
MGI:7366962 |
Age: |
embryonic day 13.5 |
Image: |
1-S1 |
|
Specimen Label: |
Control |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7366953 |
Assay Type: |
Western blot |
Annotation Date: |
2022-10-25 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1736221 |
|
Stage: |
TS21 |
Assay Id: |
MGI:7366962 |
Age: |
embryonic day 13.5 |
Image: |
1-S1 |
|
Specimen Label: |
Wnt1Cre;Kdm6bfl/fl |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6403138 |
Assay Type: |
RT-PCR |
Annotation Date: |
2020-04-07 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689421 |
|
Stage: |
TS21 |
Assay Id: |
MGI:6403154 |
Age: |
embryonic day 13.5 |
Image: |
1 |
|
Specimen Label: |
Jmjd3+/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6403138 |
Assay Type: |
RT-PCR |
Annotation Date: |
2020-04-07 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689421 |
|
Stage: |
TS21 |
Assay Id: |
MGI:6403154 |
Age: |
embryonic day 13.5 |
Image: |
1 |
|
Specimen Label: |
Jmjd3-/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6403138 |
Assay Type: |
RT-PCR |
Annotation Date: |
2020-04-07 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689426 |
|
Stage: |
TS26 |
Assay Id: |
MGI:6403168 |
Age: |
embryonic day 18.5 |
Image: |
6 |
|
Specimen Label: |
Jmjd3+/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6403138 |
Assay Type: |
RT-PCR |
Annotation Date: |
2020-04-07 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689426 |
|
Stage: |
TS26 |
Assay Id: |
MGI:6403168 |
Age: |
embryonic day 18.5 |
Image: |
6 |
|
Specimen Label: |
Jmjd3-/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6403138 |
Assay Type: |
RT-PCR |
Annotation Date: |
2024-05-21 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1796223 |
|
Stage: |
TS23 |
Assay Id: |
MGI:7641513 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
WT |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6403138 |
Assay Type: |
RT-PCR |
Annotation Date: |
2024-05-21 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1796223 |
|
Stage: |
TS23 |
Assay Id: |
MGI:7641513 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
HET |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6403138 |
Assay Type: |
RT-PCR |
Annotation Date: |
2024-05-21 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1796223 |
|
Stage: |
TS23 |
Assay Id: |
MGI:7641513 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
HOM |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4424663 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-03-20 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3270422 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:7614690 |
Age: |
embryonic day 14.5 |
|
Note: |
Subventricular zone expression was greater than in the ventricular zone. |
Specimen Label: |
Supplementary table 2 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4424663 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3270422 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:7703726 |
Age: |
embryonic day 14.5 |
Image: |
5E |
Note: |
Subventricular zone expression was greater than in the ventricular zone. |
Specimen Label: |
5E |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6403136 |
Assay Type: |
RNA in situ |
Annotation Date: |
2020-04-07 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1760624 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:6403156 |
Age: |
embryonic day 16.5 |
Image: |
1G Jmjd3+/+ left |
|
Specimen Label: |
1G Jmjd3+/+ left |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6403136 |
Assay Type: |
RNA in situ |
Annotation Date: |
2020-04-07 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737324 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:6403156 |
Age: |
embryonic day 16.5 |
Image: |
1G Jmjd3+/+ right |
|
Specimen Label: |
1G Jmjd3+/+ right |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6403136 |
Assay Type: |
RNA in situ |
Annotation Date: |
2020-04-07 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1697424 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:6403156 |
Age: |
embryonic day 16.5 |
Image: |
1G Jmjd3+/+ left |
|
Specimen Label: |
1G Jmjd3+/+ left |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4424663 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-03-20 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271122 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:7614690 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
Supplementary table 2 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4424663 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271122 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:7703726 |
Age: |
embryonic day 14.5 |
Image: |
5E |
|
Specimen Label: |
5E |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6403136 |
Assay Type: |
RNA in situ |
Annotation Date: |
2020-04-07 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1755026 |
Pattern: |
Regionally restricted |
Stage: |
TS26 |
Assay Id: |
MGI:6403162 |
Age: |
embryonic day 18.5 |
Image: |
S3D Jmjd3+/+ |
Note: |
Expression was detected in the pre-Botzinger complex. |
Specimen Label: |
S3D Jmjd3+/+ |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6403136 |
Assay Type: |
RNA in situ |
Annotation Date: |
2020-04-07 |
Strength: |
Trace |
Sex: |
Not Specified |
Emaps: |
EMAPS:1755026 |
Pattern: |
Regionally restricted |
Stage: |
TS26 |
Assay Id: |
MGI:6403162 |
Age: |
embryonic day 18.5 |
Image: |
S3D Jmjd3-/- |
Note: |
Expression was virtually undetectable in the mutant pre-Botzinger complex. |
Specimen Label: |
S3D Jmjd3-/- |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6403136 |
Assay Type: |
RNA in situ |
Annotation Date: |
2020-04-07 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3533826 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:6403162 |
Age: |
embryonic day 18.5 |
Image: |
S3D Jmjd3+/+ |
|
Specimen Label: |
S3D Jmjd3+/+ |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6403136 |
Assay Type: |
RNA in situ |
Annotation Date: |
2020-04-07 |
Strength: |
Trace |
Sex: |
Not Specified |
Emaps: |
EMAPS:3533826 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:6403162 |
Age: |
embryonic day 18.5 |
Image: |
S3D Jmjd3-/- |
Note: |
Expression was virtually undetectable in the mutant. |
Specimen Label: |
S3D Jmjd3-/- |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4424663 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-03-20 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271222 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:7614690 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
Supplementary table 2 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4424663 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271222 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:7703726 |
Age: |
embryonic day 14.5 |
Image: |
5E |
|
Specimen Label: |
5E |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6403136 |
Assay Type: |
RNA in situ |
Annotation Date: |
2020-04-07 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1778724 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:6403156 |
Age: |
embryonic day 16.5 |
Image: |
1G Jmjd3+/+ left |
|
Specimen Label: |
1G Jmjd3+/+ left |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6403136 |
Assay Type: |
RNA in situ |
Annotation Date: |
2020-04-07 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754424 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:6403156 |
Age: |
embryonic day 16.5 |
Image: |
1G Jmjd3+/+ left |
|
Specimen Label: |
1G Jmjd3+/+ left |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|