|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 7729 for Nodal

<< First    < Previous  |  Next >    Last >>
0.043s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
Type: gene
Organism: Not Specified
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 354  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 130  
Fragment?: true
Publication
First Author: Zhou X
Year: 1993
Journal: Nature
Title: Nodal is a novel TGF-beta-like gene expressed in the mouse node during gastrulation.
Volume: 361
Issue: 6412
Pages: 543-7
GXD Expression    
Probe: MGI:3654020
Assay Type: RT-PCR
Annotation Date: 2006-09-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:3654469
Age: embryonic day 17.5
Image: 2
Specimen Label: nodal
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3654020
Assay Type: RT-PCR
Annotation Date: 2006-09-13
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1737319
Stage: TS19
Assay Id: MGI:3654522
Age: embryonic day 11.5
Image: 2
Specimen Label: nodal
Specimen Num: 2
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
GXD Expression    
Probe: MGI:7465189
Assay Type: RT-PCR
Annotation Date: 2023-04-25
Strength: Present
Sex: Male
Emaps: EMAPS:1797220
Stage: TS20
Assay Id: MGI:7466255
Age: embryonic day 12.5
Image: S4
Specimen Label: Nodal +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7465189
Assay Type: RT-PCR
Annotation Date: 2023-04-25
Strength: Present
Sex: Male
Emaps: EMAPS:1797220
Stage: TS20
Assay Id: MGI:7466255
Age: embryonic day 12.5
Image: S4
Specimen Label: Nodal fl/+
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7465189
Assay Type: RT-PCR
Annotation Date: 2023-04-25
Strength: Present
Sex: Male
Emaps: EMAPS:1797220
Stage: TS20
Assay Id: MGI:7466255
Age: embryonic day 12.5
Image: S4
Specimen Label: Nodal fl/fl
Detected: true
Specimen Num: 3
Publication
First Author: Schier AF
Year: 2000
Journal: Nature
Title: Nodal signalling in vertebrate development.
Volume: 403
Issue: 6768
Pages: 385-9
GXD Expression  
Probe: MGI:7464576
Assay Type: RNA in situ
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160508
Pattern: Not Specified
Stage: TS08
Assay Id: MGI:7464815
Age: embryonic day 6.0
Note: Expression in epiblast and overlying visceral endoderm.
Specimen Label: 4 Nodal E6.0 -/-
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:7464576
Assay Type: RNA in situ
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160508
Pattern: Widespread
Stage: TS08
Assay Id: MGI:7464815
Age: embryonic day 6.0
Note: Expression in entire epiblast.
Specimen Label: 4 Nodal E6.0 WT
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:7464576
Assay Type: RNA in situ
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160518
Pattern: Not Specified
Stage: TS08
Assay Id: MGI:7464815
Age: embryonic day 6.0
Note: Expression in epiblast and overlying visceral endoderm.
Specimen Label: 4 Nodal E6.0 -/-
Detected: true
Specimen Num: 2
Publication
First Author: Liu W
Year: 2012
Journal: Biol Open
Title: Nodal mutant eXtraembryonic ENdoderm (XEN) stem cells upregulate markers for the anterior visceral endoderm and impact the timing of cardiac differentiation in mouse embryoid bodies.
Volume: 1
Issue: 3
Pages: 208-19
UniProt Feature
Begin: 245
Description: Nodal
Type: chain
End: 354
GXD Expression  
Probe: MGI:5817956
Assay Type: RNA in situ
Annotation Date: 2017-01-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607512
Pattern: Uniform
Stage: TS12
Assay Id: MGI:5817984
Age: embryonic day 8.0-8.5
Note: Symmetrical nodal expression.
Specimen Label: S1B
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:5817956
Assay Type: RNA in situ
Annotation Date: 2017-01-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607512
Pattern: Uniform
Stage: TS12
Assay Id: MGI:5817984
Age: embryonic day 8.0-8.5
Note: Symmetrical nodal expression.
Specimen Label: 3B
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5817956
Assay Type: RNA in situ
Annotation Date: 2017-01-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607512
Pattern: Uniform
Stage: TS12
Assay Id: MGI:5817984
Age: embryonic day 8.0-8.5
Note: Symmetrical nodal expression.
Specimen Label: S1C
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:5817956
Assay Type: RNA in situ
Annotation Date: 2017-01-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607512
Pattern: Uniform
Stage: TS12
Assay Id: MGI:5817984
Age: embryonic day 8.0-8.5
Note: Symmetrical nodal expression.
Specimen Label: S1D
Detected: true
Specimen Num: 8
Publication
First Author: Norris DP
Year: 1999
Journal: Genes Dev
Title: Asymmetric and node-specific nodal expression patterns are controlled by two distinct cis-acting regulatory elements.
Volume: 13
Issue: 12
Pages: 1575-88
Publication
First Author: Ma GT
Year: 2001
Journal: Dev Biol
Title: Nodal regulates trophoblast differentiation and placental development.
Volume: 236
Issue: 1
Pages: 124-35
Publication
First Author: Hueng DY
Year: 2011
Journal: J Neurooncol
Title: Inhibition of Nodal suppresses angiogenesis and growth of human gliomas.
Volume: 104
Issue: 1
Pages: 21-31
Publication
First Author: Lowe LA
Year: 2001
Journal: Development
Title: Genetic dissection of nodal function in patterning the mouse embryo.
Volume: 128
Issue: 10
Pages: 1831-43
Publication
First Author: Brennan J
Year: 2002
Journal: Genes Dev
Title: Nodal activity in the node governs left-right asymmetry.
Volume: 16
Issue: 18
Pages: 2339-44
Publication  
First Author: Yull S
Year: 2023
Journal: Front Immunol
Title: Uterine Nodal expression supports maternal immunotolerance and establishment of the FOXP3(+) regulatory T cell population during the preimplantation period.
Volume: 14
Pages: 1276979
Publication
First Author: Ware SM
Year: 2006
Journal: Dev Dyn
Title: Heart defects in X-linked heterotaxy: evidence for a genetic interaction of Zic3 with the nodal signaling pathway.
Volume: 235
Issue: 6
Pages: 1631-7
CL Term
Publication
First Author: Varlet I
Year: 1997
Journal: Development
Title: nodal expression in the primitive endoderm is required for specification of the anterior axis during mouse gastrulation.
Volume: 124
Issue: 5
Pages: 1033-44
GXD Expression      
Probe: MGI:6179155
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6190911
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Nodal
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:6179155
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:6190911
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Nodal
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:6179155
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190911
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Nodal
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:6179155
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190911
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Nodal
Detected: false
Specimen Num: 6
GXD Expression      
Probe: MGI:6179155
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6190911
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Nodal
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:6179155
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6190911
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Nodal
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:6179155
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190911
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Nodal
Detected: false
Specimen Num: 7
Publication
First Author: Wang XF
Year: 2014
Journal: Eur J Immunol
Title: Nodal promotes the generation of M2-like macrophages and downregulates the expression of IL-12.
Volume: 44
Issue: 1
Pages: 173-83
Publication  
First Author: Sauer S
Year: 2012
Journal: Front Oncol
Title: Left-right symmetry breaking in mice by left-right dynein may occur via a biased chromatid segregation mechanism, without directly involving the Nodal gene.
Volume: 2
Pages: 166
Publication  
First Author: Varlet I
Year: 1997
Journal: Cold Spring Harb Symp Quant Biol
Title: Nodal signaling and axis formation in the mouse.
Volume: 62
Pages: 105-13
Publication
First Author: Pfendler KC
Year: 2000
Journal: Genesis
Title: Nodal and bone morphogenetic protein 5 interact in murine mesoderm formation and implantation.
Volume: 28
Issue: 1
Pages: 1-14
Publication  
First Author: Arai D
Year: 2015
Journal: Mech Dev
Title: An epigenetic regulatory element of the Nodal gene in the mouse and human genomes.
Volume: 136
Pages: 143-54
Publication
First Author: Ayash TA
Year: 2020
Journal: Biol Reprod
Title: Nodal is required to maintain the uterine environment in an anti-inflammatory state during pregnancy†.
Volume: 102
Issue: 6
Pages: 1340-1350
Publication
First Author: Camus A
Year: 2006
Journal: Dev Biol
Title: Absence of Nodal signaling promotes precocious neural differentiation in the mouse embryo.
Volume: 295
Issue: 2
Pages: 743-55
Publication
First Author: Brennan J
Year: 2001
Journal: Nature
Title: Nodal signalling in the epiblast patterns the early mouse embryo.
Volume: 411
Issue: 6840
Pages: 965-9
Publication
First Author: Conlon FL
Year: 1994
Journal: Development
Title: A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse.
Volume: 120
Issue: 7
Pages: 1919-28
Publication
First Author: Marques S
Year: 2004
Journal: Genes Dev
Title: The activity of the Nodal antagonist Cerl-2 in the mouse node is required for correct L/R body axis.
Volume: 18
Issue: 19
Pages: 2342-7
Publication
First Author: Collignon J
Year: 1996
Journal: Nature
Title: Relationship between asymmetric nodal expression and the direction of embryonic turning.
Volume: 381
Issue: 6578
Pages: 155-8
Publication
First Author: Zhang YQ
Year: 2008
Journal: Dev Dyn
Title: Nodal and lefty signaling regulates the growth of pancreatic cells.
Volume: 237
Issue: 5
Pages: 1255-67
Publication
First Author: Blanchet MH
Year: 2008
Journal: Sci Signal
Title: Cripto localizes Nodal at the limiting membrane of early endosomes.
Volume: 1
Issue: 45
Pages: ra13
Publication
First Author: Tanaka Y
Year: 2023
Journal: Dev Cell
Title: Nodal flow transfers polycystin to determine mouse left-right asymmetry.
Volume: 58
Issue: 16
Pages: 1447-1461.e6
Publication
First Author: Meno C
Year: 2001
Journal: Dev Cell
Title: Diffusion of nodal signaling activity in the absence of the feedback inhibitor Lefty2.
Volume: 1
Issue: 1
Pages: 127-38
Publication
First Author: Perea-Gomez A
Year: 2002
Journal: Dev Cell
Title: Nodal antagonists in the anterior visceral endoderm prevent the formation of multiple primitive streaks.
Volume: 3
Issue: 5
Pages: 745-56
Publication
First Author: Chen C
Year: 2004
Journal: Curr Biol
Title: Two modes by which Lefty proteins inhibit nodal signaling.
Volume: 14
Issue: 7
Pages: 618-24
Publication
First Author: Houtmeyers R
Year: 2016
Journal: Hum Mol Genet
Title: Zic2 mutation causes holoprosencephaly via disruption of NODAL signalling.
Volume: 25
Issue: 18
Pages: 3946-3959
Publication
First Author: Saijoh Y
Year: 2003
Journal: Dev Biol
Title: Left-right patterning of the mouse lateral plate requires nodal produced in the node.
Volume: 256
Issue: 1
Pages: 160-72
Publication
First Author: Yamamoto M
Year: 2004
Journal: Nature
Title: Nodal antagonists regulate formation of the anteroposterior axis of the mouse embryo.
Volume: 428
Issue: 6981
Pages: 387-92
Publication
First Author: Andersson O
Year: 2006
Journal: Dev Biol
Title: Synergistic interaction between Gdf1 and Nodal during anterior axis development.
Volume: 293
Issue: 2
Pages: 370-81
Publication
First Author: Tanaka C
Year: 2007
Journal: Genes Dev
Title: Long-range action of Nodal requires interaction with GDF1.
Volume: 21
Issue: 24
Pages: 3272-82
Publication
First Author: Kumar A
Year: 2008
Journal: Dev Dyn
Title: Broad mesodermal and endodermal deletion of Nodal at postgastrulation stages results solely in left/right axial defects.
Volume: 237
Issue: 12
Pages: 3591-601
Publication
First Author: Hadjantonakis AK
Year: 2008
Journal: PLoS One
Title: Tbx6 regulates left/right patterning in mouse embryos through effects on nodal cilia and perinodal signaling.
Volume: 3
Issue: 6
Pages: e2511
Publication
First Author: Liguori GL
Year: 2008
Journal: Dev Biol
Title: Cripto-independent Nodal signaling promotes positioning of the A-P axis in the early mouse embryo.
Volume: 315
Issue: 2
Pages: 280-9
Publication
First Author: Vincent SD
Year: 2004
Journal: Mech Dev
Title: Asymmetric Nodal expression in the mouse is governed by the combinatorial activities of two distinct regulatory elements.
Volume: 121
Issue: 11
Pages: 1403-15
Publication
First Author: Mesnard D
Year: 2006
Journal: Development
Title: Nodal specifies embryonic visceral endoderm and sustains pluripotent cells in the epiblast before overt axial patterning.
Volume: 133
Issue: 13
Pages: 2497-505
Publication
First Author: Iratni R
Year: 2002
Journal: Science
Title: Inhibition of excess nodal signaling during mouse gastrulation by the transcriptional corepressor DRAP1.
Volume: 298
Issue: 5600
Pages: 1996-9
GXD Expression
Probe: MGI:1343263
Assay Type: RNA in situ
Annotation Date: 1999-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1617912
Pattern: Regionally restricted
Stage: TS12
Assay Id: MGI:1343319
Age: embryonic day 8.0
Image: 5A
Note: Nodal is expressed on the left side of normal embryos.
Specimen Label: 5A
Detected: true
Specimen Num: 1
Publication
First Author: Park CB
Year: 2012
Journal: Biol Reprod
Title: NODAL in the uterus is necessary for proper placental development and maintenance of pregnancy.
Volume: 86
Issue: 6
Pages: 194
Publication
First Author: Kruithof-de Julio M
Year: 2011
Journal: Development
Title: Regulation of extra-embryonic endoderm stem cell differentiation by Nodal and Cripto signaling.
Volume: 138
Issue: 18
Pages: 3885-95
Publication
First Author: Trichas G
Year: 2011
Journal: PLoS Biol
Title: Nodal dependent differential localisation of dishevelled-2 demarcates regions of differing cell behaviour in the visceral endoderm.
Volume: 9
Issue: 2
Pages: e1001019
Publication
First Author: Meno C
Year: 1999
Journal: Mol Cell
Title: Mouse Lefty2 and zebrafish antivin are feedback inhibitors of nodal signaling during vertebrate gastrulation.
Volume: 4
Issue: 3
Pages: 287-98
Publication
First Author: Ishimura A
Year: 2008
Journal: Dev Dyn
Title: Man1, an inner nuclear membrane protein, regulates left-right axis formation by controlling nodal signaling in a node-independent manner.
Volume: 237
Issue: 12
Pages: 3565-76
Publication
First Author: Beck S
Year: 2002
Journal: Nat Cell Biol
Title: Extraembryonic proteases regulate Nodal signalling during gastrulation.
Volume: 4
Issue: 12
Pages: 981-5
Publication
First Author: Pereira PN
Year: 2012
Journal: Development
Title: Antagonism of Nodal signaling by BMP/Smad5 prevents ectopic primitive streak formation in the mouse amnion.
Volume: 139
Issue: 18
Pages: 3343-54
Publication
First Author: Dahle Ø
Year: 2010
Journal: Sci Signal
Title: Nodal signaling recruits the histone demethylase Jmjd3 to counteract polycomb-mediated repression at target genes.
Volume: 3
Issue: 127
Pages: ra48
Publication
First Author: Blanchet MH
Year: 2008
Journal: EMBO J
Title: Cripto recruits Furin and PACE4 and controls Nodal trafficking during proteolytic maturation.
Volume: 27
Issue: 19
Pages: 2580-91
Publication
First Author: Spiller CM
Year: 2012
Journal: Development
Title: Endogenous Nodal signaling regulates germ cell potency during mammalian testis development.
Volume: 139
Issue: 22
Pages: 4123-32
Publication
First Author: Adachi H
Year: 1999
Journal: Genes Dev
Title: Determination of left/right asymmetric expression of nodal by a left side-specific enhancer with sequence similarity to a lefty-2 enhancer.
Volume: 13
Issue: 12
Pages: 1589-600
Publication
First Author: Zhao F
Year: 2012
Journal: Am J Physiol Endocrinol Metab
Title: Nodal induces apoptosis through activation of the ALK7 signaling pathway in pancreatic INS-1 β-cells.
Volume: 303
Issue: 1
Pages: E132-43
Publication
First Author: Lowe LA
Year: 1996
Journal: Nature
Title: Conserved left-right asymmetry of nodal expression and alterations in murine situs inversus.
Volume: 381
Issue: 6578
Pages: 158-61
Publication
First Author: Yamamoto M
Year: 2003
Journal: Development
Title: Nodal signaling induces the midline barrier by activating Nodal expression in the lateral plate.
Volume: 130
Issue: 9
Pages: 1795-804
Publication
First Author: Lee GH
Year: 2016
Journal: J Cell Biol
Title: A GPI processing phospholipase A2, PGAP6, modulates Nodal signaling in embryos by shedding CRIPTO.
Volume: 215
Issue: 5
Pages: 705-718
Publication
First Author: Norris DP
Year: 2002
Journal: Development
Title: The Foxh1-dependent autoregulatory enhancer controls the level of Nodal signals in the mouse embryo.
Volume: 129
Issue: 14
Pages: 3455-68
Publication
First Author: Guzman-Ayala M
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Nodal protein processing and fibroblast growth factor 4 synergize to maintain a trophoblast stem cell microenvironment.
Volume: 101
Issue: 44
Pages: 15656-60
Publication
First Author: Larkins CE
Year: 2012
Journal: Dev Biol
Title: Defective Nodal and Cerl2 expression in the Arl13b(hnn) mutant node underlie its heterotaxia.
Volume: 367
Issue: 1
Pages: 15-24
Publication
First Author: Tavares AT
Year: 2007
Journal: Development
Title: Cerberus is a feedback inhibitor of Nodal asymmetric signaling in the chick embryo.
Volume: 134
Issue: 11
Pages: 2051-60
Publication
First Author: Krebs LT
Year: 2003
Journal: Genes Dev
Title: Notch signaling regulates left-right asymmetry determination by inducing Nodal expression.
Volume: 17
Issue: 10
Pages: 1207-12
Publication
First Author: Powers SE
Year: 2010
Journal: Development
Title: Tgif1 and Tgif2 regulate Nodal signaling and are required for gastrulation.
Volume: 137
Issue: 2
Pages: 249-59
Publication
First Author: Kim YY
Year: 2014
Journal: PLoS One
Title: Meteorin regulates mesendoderm development by enhancing nodal expression.
Volume: 9
Issue: 2
Pages: e88811
GO Term