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Search results 401 to 448 out of 448 for Selp

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Type Details Score
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Protein
P70274
Organism: Mus musculus/domesticus
Length: 380  
Fragment?: false
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Allele
Selp<em1Smoc> | MGI:7292211
Name: selectin, platelet; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6429523 | C57BL/6J-Selp<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Protein Domain
IPR007672 | SelP_C
Type: Domain
Description: SelP is the only known eukaryotic selenoprotein that contains multiple selenocysteine (Sec) residues, and accounts for more than 50% of the selenium content of rat and human plasma []. It is thought to be glycosylated []. SelP may have antioxidant properties. It can attach to epithelial cells, and may protect vascular endothelial cells against peroxynitrite toxicity []. The high selenium content of SelP suggests that it may be involved in selenium intercellular transport or storage []. The promoter structure of bovine SelP suggests that it may be involved in countering heavy metal intoxication, and may also have a developmental function []. The N-terminal region always contains one Sec residue, and this is separated from the C-terminal region (9-16 sec residues) by a histidine-rich sequence []. The large number of Sec residues in the C-terminal portion of SelP suggests that it may be involved in selenium transport or storage. However, it is also possible that this region has a redox function [].
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Protein Coding Gene
MGI:894288 | Selenop
Type: protein_coding_gene
Organism: mouse, laboratory
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Allele
Tg(SELP)3Rpmc | MGI:5776219
Name: transgene insertion 3, Rodger P McEver
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Publication
11168591 | -
First Author: Kryukov GV
Year: 2000
Journal: Genes Cells
Title: Selenium metabolism in zebrafish: multiplicity of selenoprotein genes and expression of a protein containing 17 selenocysteine residues.
Volume: 5
Issue: 12
Pages: 1049-60
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Publication
9358058 | -
First Author: Fujii M
Year: 1997
Journal: Gene
Title: Analysis of bovine selenoprotein P-like protein gene and availability of metal responsive element (MRE) located in its promoter.
Volume: 199
Issue: 1-2
Pages: 211-7
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Publication
17311913 | J:121127
First Author: Hill KE
Year: 2007
Journal: J Biol Chem
Title: The selenium-rich C-terminal domain of mouse selenoprotein P is necessary for the supply of selenium to brain and testis but not for the maintenance of whole body selenium.
Volume: 282
Issue: 15
Pages: 10972-80
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Protein Domain
IPR007671 | Selenoprotein-P_N
Type: Domain
Description: SelP is the only known eukaryotic selenoprotein that contains multiple selenocysteine (Sec) residues, and accounts for more than 50% of the selenium content of rat and human plasma []. It is thought to be glycosylated []. SelP may have antioxidant properties. It can attach to epithelial cells, and may protect vascular endothelial cells against peroxynitrite toxicity []. The high selenium content of SelP suggests that it may be involved in selenium intercellular transport or storage []. The promoter structure of bovine SelP suggests that it may be involved in countering heavy metal intoxication, and may also have a developmental function [].This entry represents the N-terminal region of SelP, which can exist independently of the C-terminal region. The N terminus is larger, contains less Selenium and is thought to be heavily glycosylated. It appears to supply selenium to the kidney []. Zebrafish selenoprotein Pb () lacks the C-terminal Sec-rich region, and a protein encoded by the rat SelP gene and lacking this region has also been reported []. The N-terminal region contains a conserved SecxxCys motif, which is similar to the CysxxCys found in thioredoxins. It is speculated that the N-terminal region may adopt a thioredoxin fold and catalyse redox reactions []. The N-terminal region also contains a His-rich region, which is thought to mediate heparin binding. Binding to heparan proteoglycans could account for the membrane binding properties of SelP [].The function of the bacterial members of this family is uncharacterised.
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Allele
Tg(PECAM1-TFPI/CD4/SELP)#aAdor | MGI:5578129
Name: transgene insertion #a, Anthony Dorling
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(PECAM1-hir/CD4/SELP)#aAdor | MGI:5578128
Name: transgene insertion #a, Anthony Dorling
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(ACTA2-TFPI/CD4/SELP)#aAdor | MGI:5578126
Name: transgene insertion #a, Anthony Dorling
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(ACTA2-hir/CD4/SELP)#aAdor | MGI:5578127
Name: transgene insertion #a, Anthony Dorling
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Alb-Selp)9Rpmc | MGI:5908730
Name: transgene insertion 9, Rodger P McEver
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Sell<tm2Alb> | MGI:3767069
Name: selectin, lymphocyte; targeted mutation 2, Arthur L Beaudet
Allele Type: Targeted
Attribute String: Null/knockout
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Protein
E0CX80
Organism: Mus musculus/domesticus
Length: 177  
Fragment?: true
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Protein
E0CZ76
Organism: Mus musculus/domesticus
Length: 124  
Fragment?: true
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Protein
E0CY03
Organism: Mus musculus/domesticus
Length: 110  
Fragment?: true
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Publication
10775431 | J:61582
First Author: Mostert V
Year: 2000
Journal: Arch Biochem Biophys
Title: Selenoprotein P: properties, functions, and regulation.
Volume: 376
Issue: 2
Pages: 433-8
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Strain
MGI:6119405 | B6.Cg-Tg(PECAM1-TFPI/CD4/SELP)#aAdor/AdorH
Attribute String: mutant strain, transgenic, congenic
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Strain
MGI:6119406 | B6.Cg-Tg(PECAM1-hir/CD4/SELP)#aAdor/H
Attribute String: congenic, mutant strain, transgenic
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Publication
33458623 | J:322010
First Author: Wilkinson H
Year: 2021
Journal: iScience
Title: PAR-1 signaling on macrophages is required for effective in vivo delayed-type hypersensitivity responses.
Volume: 24
Issue: 1
Pages: 101981
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Strain
MGI:6119404 | B6.Cg-Tg(ACTA2-TFPI/CD4/SELP)#aAdor/AdorH
Attribute String: mutant strain, transgenic, congenic
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Publication
25677604 | J:234131
First Author: Chen D
Year: 2015
Journal: Circulation
Title: Expression of human tissue factor pathway inhibitor on vascular smooth muscle cells inhibits secretion of macrophage migration inhibitory factor and attenuates atherosclerosis in ApoE-/- mice.
Volume: 131
Issue: 15
Pages: 1350-60
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Allele
Sell<tm1Alb> | MGI:2656258
Name: selectin, lymphocyte; targeted mutation 1, Arthur L Beaudet
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:5908733 | C57BL/6-Tg(Alb-Selp)9Rpmc/J
Attribute String: coisogenic, mutant strain, transgenic
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Strain
MGI:5776223 | B6.Cg-Selp<tm1Bay> Tg(SELP)3Rpmc/J
Attribute String: congenic, mutant strain, targeted mutation, transgenic
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Genotype
Genotype
Symbol: Sell/Sell
Background: involves: 129S7/SvEvBrd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Publication
15126322 | J:92695
First Author: Chen D
Year: 2004
Journal: Blood
Title: Inhibition of intravascular thrombosis in murine endotoxemia by targeted expression of hirudin and tissue factor pathway inhibitor analogs to activated endothelium.
Volume: 104
Issue: 5
Pages: 1344-9
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Publication
16803463 | J:135627
First Author: Chen D
Year: 2006
Journal: J Thromb Haemost
Title: Postinjury vascular intimal hyperplasia in mice is completely inhibited by CD34+ bone marrow-derived progenitor cells expressing membrane-tethered anticoagulant fusion proteins.
Volume: 4
Issue: 10
Pages: 2191-8
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Publication
33876187 | J:315674
First Author: Flohr Svendsen A
Year: 2021
Journal: Blood
Title: A comprehensive transcriptome signature of murine hematopoietic stem cell aging.
Volume: 138
Issue: 6
Pages: 439-451
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Publication
18606855 | J:263056
First Author: Chen D
Year: 2008
Journal: J Exp Med
Title: Protease-activated receptor 1 activation is necessary for monocyte chemoattractant protein 1-dependent leukocyte recruitment in vivo.
Volume: 205
Issue: 8
Pages: 1739-46
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Genotype
Genotype
Symbol: Sele/Sele Sell/Sell Selp/Selp
Background: involves: 129S7/SvEvBrd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Publication
9687017 | J:49017
First Author: Steinert P
Year: 1998
Journal: Biol Chem
Title: Analysis of the mouse selenoprotein P gene.
Volume: 379
Issue: 6
Pages: 683-91
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Publication
23648484 | J:204483
First Author: Fujita R
Year: 2013
Journal: Mol Cell Biol
Title: NF-E2 p45 is important for establishing normal function of platelets.
Volume: 33
Issue: 14
Pages: 2659-70
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Publication
23717578 | J:200717
First Author: Pencovich N
Year: 2013
Journal: PLoS One
Title: Cell-autonomous function of Runx1 transcriptionally regulates mouse megakaryocytic maturation.
Volume: 8
Issue: 5
Pages: e64248
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Publication
23376466 | J:336963
First Author: Chamoto K
Year: 2013
Journal: Stem Cell Res
Title: Migration of CD11b+ accessory cells during murine lung regeneration.
Volume: 10
Issue: 3
Pages: 267-77
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Publication
12781685 | J:83702
First Author: Buttitta L
Year: 2003
Journal: Dev Biol
Title: Microarray analysis of somitogenesis reveals novel targets of different WNT signaling pathways in the somitic mesoderm.
Volume: 258
Issue: 1
Pages: 91-104
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Publication
23516969 | J:277259
First Author: Chen D
Year: 2013
Journal: J Thromb Haemost
Title: Fibrocytes mediate intimal hyperplasia post-vascular injury and are regulated by two tissue factor-dependent mechanisms.
Volume: 11
Issue: 5
Pages: 963-74
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Publication
24586312 | J:208464
First Author: Kayashima Y
Year: 2014
Journal: PLoS One
Title: Quantitative trait loci affecting atherosclerosis at the aortic root identified in an intercross between DBA2J and 129S6 apolipoprotein E-null mice.
Volume: 9
Issue: 2
Pages: e88274
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Publication
35110605 | J:319756
First Author: Turovsky EA
Year: 2022
Journal: Sci Rep
Title: Features of the cytoprotective effect of selenium nanoparticles on primary cortical neurons and astrocytes during oxygen-glucose deprivation and reoxygenation.
Volume: 12
Issue: 1
Pages: 1710
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