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Search results 201 to 300 out of 426 for Agrn

0.042s
Type Details Score
GXD Expression
Probe: MGI:6714215
Assay Type: RNA in situ
Annotation Date: 2021-06-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6714276
Age: embryonic day 14.0
Image: 6C
Note: Expression most abundant in postmitotic cells of cortical plate.
Specimen Label: 6C
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6477028
Assay Type: Immunohistochemistry
Annotation Date: 2020-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1770126
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6477287
Age: embryonic day 18.5
Note: Expression in neuromuscular junctions in ventral part of diaphragm.
Specimen Label: +/- not shown
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6477028
Assay Type: Immunohistochemistry
Annotation Date: 2020-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1770126
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6477287
Age: embryonic day 18.5
Note: Levels expression unchanged compared with control diaphragm.
Specimen Label: -/- not shown
Detected: true
Specimen Num: 2
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6714259
Age: embryonic day 14.0
Image: 6B
Note: Expression in neural progenitors in intermediate zones of cerebral cortex.
Specimen Label: 6B
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6714215
Assay Type: RNA in situ
Annotation Date: 2021-06-09
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3271222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6714276
Age: embryonic day 14.0
Image: 6C
Note: Moderate expression in migrating neuroblast of intermediate zone.v
Specimen Label: 6C
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:1825930
Assay Type: RNA in situ
Annotation Date: 2011-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616617
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:5295384
Age: embryonic day 10.5
Image: 1
Note: Expression is present in the lateral ventral horns.
Specimen Label: 1
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3584633
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915527
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3585500
Age: postnatal day 2-3
Image: P2/3
Note: Expression was detected in the inner neuroblastic layer.
Specimen Label: P2/3
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:3584633
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585500
Age: postnatal day 4-5
Image: P4/5
Note: Expression was detected in the inner neuroblastic layer.
Specimen Label: P4/5
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:3584633
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585500
Age: postnatal day 6-7
Image: P6/7
Specimen Label: P6/7
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:3584633
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585500
Age: postnatal day 8-10
Image: P8/10
Specimen Label: P8/10
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:3837736
Assay Type: Immunohistochemistry
Annotation Date: 2009-03-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2694224
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3838000
Age: embryonic day 16.5
Image: S7 agrin
Specimen Label: S7 agrin
Detected: true
Specimen Num: 1
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752826
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6714259
Age: embryonic day 18.0
Image: 6G
Note: Expression in epidermal cells abutting the basal lamina separating dermis from epidermis.
Specimen Label: 6G
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:7377698
Assay Type: Immunohistochemistry
Annotation Date: 2022-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7377699
Age: embryonic day 14.5
Image: 3G
Note: Expression is in the skin basement membrane.
Specimen Label: 3G
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:7377698
Assay Type: Immunohistochemistry
Annotation Date: 2022-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7377699
Age: embryonic day 14.5
Image: 3H
Note: In this mutant expression is in the skin basement membrane is the same as in wild-type.
Specimen Label: 3H
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:3584633
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585500
Age: postnatal day 6
Specimen Label: CNS
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:6714215
Assay Type: RNA in situ
Annotation Date: 2021-06-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:6714276
Age: embryonic day 18.0
Image: 6N
Specimen Label: 6N
Detected: false
Specimen Num: 5
GXD Expression  
Probe: MGI:6714228
Assay Type: Immunohistochemistry
Annotation Date: 2021-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6714280
Age: embryonic day 18.0
Note: Expression in basal lamina.
Specimen Label: wild-type not shown
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:6714228
Assay Type: Immunohistochemistry
Annotation Date: 2021-06-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:6714280
Age: embryonic day 18.0
Specimen Label: E16 LN/LN not shown
Detected: false
Specimen Num: 8
GXD Expression      
Probe: MGI:6714228
Assay Type: Immunohistochemistry
Annotation Date: 2021-06-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:6714280
Age: postnatal newborn
Specimen Label: neonate LN/LN not shown
Detected: false
Specimen Num: 9
GXD Expression  
Probe: MGI:5532695
Assay Type: Immunohistochemistry
Annotation Date: 2014-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5532710
Age: embryonic day 12.0
Image: E12
Specimen Label: E12
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3584633
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585500
Age: postnatal day 6
Specimen Label: CNS
Detected: true
Specimen Num: 9
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284526
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6714259
Age: embryonic day 18.0
Image: 6D
Note: Expression restricted to near ventricles and in blood vessels.
Specimen Label: 6D
Detected: true
Specimen Num: 3
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666826
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6714259
Age: embryonic day 18.0
Image: 6E
Note: Expression in sensory neurons of dorsal root ganglion.
Specimen Label: 6E
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:6714215
Assay Type: RNA in situ
Annotation Date: 2021-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666826
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6714276
Age: embryonic day 18.0
Image: 6F
Note: Expression widely distributed in many neuronal cell types in both dorsal root ganglia and spinal cord.
Specimen Label: 6F
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3584633
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603924
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3585500
Age: embryonic day 16.0
Note: Expression was widespread.
Specimen Label: Embryo
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:6416295
Assay Type: Immunohistochemistry
Annotation Date: 2020-05-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1844126
Pattern: Widespread
Stage: TS26
Assay Id: MGI:6416325
Age: embryonic day 18.5
Note: Expressed in both neurons and glia.
Specimen Label: 1a wild type
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6416295
Assay Type: Immunohistochemistry
Annotation Date: 2020-05-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1844126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6416325
Age: embryonic day 18.5
Note: Significantly diminished expression and colocalized with synaptophysin-labeled nerve terminals.
Specimen Label: 1a z+ agrin -/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6416295
Assay Type: Immunohistochemistry
Annotation Date: 2020-05-13
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1844126
Stage: TS26
Assay Id: MGI:6416325
Age: embryonic day 18.5
Specimen Label: 1a AGD -/-
Detected: false
Specimen Num: 3
GXD Expression
Probe: MGI:3584633
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915727
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:3585500
Age: postnatal day 2-3
Image: P2/3
Note: Expression was detected in the vitreal outer neuroblastic layer.
Specimen Label: P2/3
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:3584633
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3585500
Age: postnatal day 4-5
Image: P4/5
Note: Expression was detected in the vitreal outer neuroblastic layer.
Specimen Label: P4/5
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:3837736
Assay Type: Immunohistochemistry
Annotation Date: 2009-03-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1829524
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3838000
Age: embryonic day 16.5
Image: S7 agrin
Specimen Label: S7 agrin
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6714215
Assay Type: RNA in situ
Annotation Date: 2021-06-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1715726
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6714276
Age: embryonic day 18.0
Specimen Label: not shown
Detected: true
Specimen Num: 3
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286026
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6714259
Age: embryonic day 18.0
Image: 6K
Note: Expression in pulmonary epithelial cells.
Specimen Label: 6K
Detected: true
Specimen Num: 10
GXD Expression
Probe: MGI:6714228
Assay Type: Immunohistochemistry
Annotation Date: 2021-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266326
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6714280
Age: embryonic day 18.0
Image: 7E
Note: Expression in meningeal sheath - i.e. basal lamina of pia and sheath of optic nerve.
Specimen Label: 7E
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6714228
Assay Type: Immunohistochemistry
Annotation Date: 2021-06-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3266326
Stage: TS26
Assay Id: MGI:6714280
Age: embryonic day 18.0
Image: 7F
Specimen Label: 7F
Detected: false
Specimen Num: 6
GXD Expression  
Probe: MGI:5532695
Assay Type: Immunohistochemistry
Annotation Date: 2014-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5532710
Age: embryonic day 14.0
Image: E14
Specimen Label: E14
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5532695
Assay Type: Immunohistochemistry
Annotation Date: 2014-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270024
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:5532710
Age: embryonic day 16.0
Image: E16
Specimen Label: E16
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:5532695
Assay Type: Immunohistochemistry
Annotation Date: 2014-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270027
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:5532710
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:5532695
Assay Type: Immunohistochemistry
Annotation Date: 2014-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5532710
Age: postnatal day 7
Image: P7
Specimen Label: P7
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:5532695
Assay Type: Immunohistochemistry
Annotation Date: 2014-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5532710
Age: postnatal day 15
Image: P15
Specimen Label: P15
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:3584633
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1646924
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3585500
Age: embryonic day 16.0
Specimen Label: Embryo
Detected: true
Specimen Num: 10
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1646928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6714259
Age: postnatal adult
Image: 6I
Note: Expression in motoneurons persisted into adulthood.
Specimen Label: 6I
Detected: true
Specimen Num: 8
GXD Expression
Probe: MGI:3584633
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3574228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3585500
Age: postnatal day 6-7
Image: P6/7
Note: Expression was detected in amacrine cells.
Specimen Label: P6/7
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:3584633
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Male
Emaps: EMAPS:3574228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3585500
Age: postnatal adult
Image: Adult
Note: Expression was detected in amacrine cells.
Specimen Label: Adult
Detected: true
Specimen Num: 8
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-06-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6714259
Age: embryonic day 14.0
Image: 6B
Note: Expression in neural progenitors, highest levels in ventricular zone, of cerebral cortex.
Specimen Label: 6B
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6714215
Assay Type: RNA in situ
Annotation Date: 2021-06-09
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6714276
Age: embryonic day 14.0
Image: 6C
Note: Lowest expression in progenitors of ventricular zone.
Specimen Label: 6C
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:1054754
Assay Type: RNA in situ
Annotation Date: 2024-01-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7576043
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6714215
Assay Type: RNA in situ
Annotation Date: 2021-06-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1679726
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6714276
Age: embryonic day 18.0
Specimen Label: not shown
Detected: true
Specimen Num: 3
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1679726
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6714259
Age: embryonic day 18.0
Specimen Label: not shown
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:3584633
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3573928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585500
Age: postnatal day 6-7
Image: P6/7
Specimen Label: P6/7
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6714215
Assay Type: RNA in situ
Annotation Date: 2021-06-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752526
Stage: TS26
Assay Id: MGI:6714276
Age: embryonic day 18.0
Note: Expression undetectable in all nonneural tissues tested, including skin.
Specimen Label: not shown
Detected: false
Specimen Num: 3
GXD Expression  
Probe: MGI:6714228
Assay Type: Immunohistochemistry
Annotation Date: 2021-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752526
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6714280
Age: embryonic day 18.0
Note: Expression in basal lamina.
Specimen Label: wild-type not shown
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:6714228
Assay Type: Immunohistochemistry
Annotation Date: 2021-06-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752526
Stage: TS26
Assay Id: MGI:6714280
Age: embryonic day 18.0
Specimen Label: E16 LN/LN not shown
Detected: false
Specimen Num: 8
GXD Expression      
Probe: MGI:6714228
Assay Type: Immunohistochemistry
Annotation Date: 2021-06-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752527
Stage: TS27
Assay Id: MGI:6714280
Age: postnatal newborn
Specimen Label: neonate LN/LN not shown
Detected: false
Specimen Num: 9
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2823926
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6714259
Age: embryonic day 18.0
Image: 6J
Note: Expression in kidney glomeruli and a subset of tubules.
Specimen Label: 6J
Detected: true
Specimen Num: 9
GXD Expression
Probe: MGI:6714228
Assay Type: Immunohistochemistry
Annotation Date: 2021-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2823926
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6714280
Age: embryonic day 18.0
Image: 7C
Note: Expression in glomerular basement membrane.
Specimen Label: 7C
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6714228
Assay Type: Immunohistochemistry
Annotation Date: 2021-06-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2823926
Stage: TS26
Assay Id: MGI:6714280
Age: embryonic day 18.0
Image: 7D
Specimen Label: 7D
Detected: false
Specimen Num: 4
GXD Expression  
Probe: MGI:1825930
Assay Type: RNA in situ
Annotation Date: 2011-11-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1619117
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:5295384
Age: embryonic day 10.5
Image: 1
Specimen Label: 1
Detected: true
Specimen Num: 1
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-06-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1757726
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6714259
Age: embryonic day 18.0
Image: 6E
Note: Strong expression in motoneurons in spinal cord.
Specimen Label: 6E
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:6714215
Assay Type: RNA in situ
Annotation Date: 2021-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757726
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6714276
Age: embryonic day 18.0
Image: 6F
Note: Expression widely distributed in many neuronal cell types in both dorsal root ganglia and spinal cord.
Specimen Label: 6F
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6714228
Assay Type: Immunohistochemistry
Annotation Date: 2021-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757526
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6714280
Age: embryonic day 18.0
Image: 7E
Note: Expression in meningeal sheath - i.e. basal lamina of pia and sheath of optic nerve.
Specimen Label: 7E
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6714228
Assay Type: Immunohistochemistry
Annotation Date: 2021-06-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757526
Stage: TS26
Assay Id: MGI:6714280
Age: embryonic day 18.0
Image: 7F
Specimen Label: 7F
Detected: false
Specimen Num: 6
GXD Expression
Probe: MGI:7469475
Assay Type: Immunohistochemistry
Annotation Date: 2023-05-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274826
Pattern: Widespread
Stage: TS26
Assay Id: MGI:7469492
Age: embryonic day 18.0
Image: 1A
Note: Expression throughout ventricular myocardium.
Specimen Label: 1A
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:7469475
Assay Type: Immunohistochemistry
Annotation Date: 2023-05-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7469492
Age: postnatal adult
Image: 1B
Note: Expression relatively evenly distributed.
Specimen Label: 1B
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:3584633
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1717122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3585500
Age: embryonic day 14.0
Image: E14
Note: Expression was detected in the inner neuroblastic layer.
Specimen Label: E14
Detected: true
Specimen Num: 1
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2778226
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6714259
Age: embryonic day 18.0
Image: 6J
Note: Expression in kidney glomeruli and a subset of tubules.
Specimen Label: 6J
Detected: true
Specimen Num: 9
GXD Expression
Probe: MGI:7377698
Assay Type: Immunohistochemistry
Annotation Date: 2022-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7377699
Age: embryonic day 14.5
Image: 3C
Note: Expression is in the basement membrane of the visceral pleura and conducting airways.
Specimen Label: 3C
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:7377698
Assay Type: Immunohistochemistry
Annotation Date: 2022-10-31
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3803122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7377699
Age: embryonic day 14.5
Image: 3D
Note: Expression is in the basement membrane of the visceral pleura and conducting airways. The reduction was more pronounced in the visceral pleura basement membrane.
Specimen Label: 3D
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:7377698
Assay Type: Immunohistochemistry
Annotation Date: 2022-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7377699
Age: embryonic day 14.5
Image: 3G
Note: Expression is in the skin basement membrane.
Specimen Label: 3G
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:7377698
Assay Type: Immunohistochemistry
Annotation Date: 2022-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7377699
Age: embryonic day 14.5
Image: 3H
Note: In this mutant expression is in the skin basement membrane is the same as in wild-type.
Specimen Label: 3H
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:7377698
Assay Type: Immunohistochemistry
Annotation Date: 2022-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7377699
Age: embryonic day 18.5
Image: 4H
Specimen Label: 4H
Detected: true
Specimen Num: 5
GXD Expression
Probe: MGI:7377698
Assay Type: Immunohistochemistry
Annotation Date: 2022-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3803126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7377699
Age: embryonic day 18.5
Image: 4I
Note: This mutant has disorganized basement membranes compared to wild-type.
Specimen Label: 4I
Detected: true
Specimen Num: 6
Publication
First Author: Stephan A
Year: 2008
Journal: FASEB J
Title: Neurotrypsin cleaves agrin locally at the synapse.
Volume: 22
Issue: 6
Pages: 1861-73
Publication
First Author: Matsumoto-Miyai K
Year: 2009
Journal: Cell
Title: Coincident pre- and postsynaptic activation induces dendritic filopodia via neurotrypsin-dependent agrin cleavage.
Volume: 136
Issue: 6
Pages: 1161-71
Publication
First Author: Bütikofer L
Year: 2011
Journal: FASEB J
Title: Destabilization of the neuromuscular junction by proteolytic cleavage of agrin results in precocious sarcopenia.
Volume: 25
Issue: 12
Pages: 4378-93
Publication
First Author: Qiao C
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Amelioration of laminin-alpha2-deficient congenital muscular dystrophy by somatic gene transfer of miniagrin.
Volume: 102
Issue: 34
Pages: 11999-2004
Publication
First Author: Denzer AJ
Year: 1997
Journal: J Cell Biol
Title: Agrin binds to the nerve-muscle basal lamina via laminin.
Volume: 137
Issue: 3
Pages: 671-83
Publication
First Author: Reif R
Year: 2007
Journal: FASEB J
Title: Specific cleavage of agrin by neurotrypsin, a synaptic protease linked to mental retardation.
Volume: 21
Issue: 13
Pages: 3468-78
Publication
First Author: Daryadel A
Year: 2016
Journal: PLoS One
Title: The C-Terminal Fragment of Agrin (CAF), a Novel Marker of Renal Function, Is Filtered by the Kidney and Reabsorbed by the Proximal Tubule.
Volume: 11
Issue: 7
Pages: e0157905
Publication
First Author: Vannoy CH
Year: 2017
Journal: Am J Pathol
Title: Adeno-Associated Virus-Mediated Mini-Agrin Delivery Is Unable to Rescue Disease Phenotype in a Mouse Model of Limb Girdle Muscular Dystrophy Type 2I.
Volume: 187
Issue: 2
Pages: 431-440
Publication
First Author: Yumoto N
Year: 2012
Journal: Nature
Title: Lrp4 is a retrograde signal for presynaptic differentiation at neuromuscular synapses.
Volume: 489
Issue: 7416
Pages: 438-42
Publication
First Author: Bais P
Year: 2016
Journal: Biol Open
Title: Metabolite profile of a mouse model of Charcot-Marie-Tooth type 2D neuropathy: implications for disease mechanisms and interventions.
Volume: 5
Issue: 7
Pages: 908-20
Publication
First Author: Samuel MA
Year: 2012
Journal: PLoS One
Title: Agrin and synaptic laminin are required to maintain adult neuromuscular junctions.
Volume: 7
Issue: 10
Pages: e46663
Publication
First Author: Misgeld T
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Agrin promotes synaptic differentiation by counteracting an inhibitory effect of neurotransmitter.
Volume: 102
Issue: 31
Pages: 11088-93
Publication
First Author: Lin S
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Muscle-wide secretion of a miniaturized form of neural agrin rescues focal neuromuscular innervation in agrin mutant mice.
Volume: 105
Issue: 32
Pages: 11406-11
Publication
First Author: Cifuentes-Diaz C
Year: 2000
Journal: Mech Dev
Title: Regulated expression of the proteoglycan SPOCK in the neuromuscular system.
Volume: 94
Issue: 1-2
Pages: 277-82
Publication
First Author: O'Connor E
Year: 2018
Journal: Hum Mol Genet
Title: MYO9A deficiency in motor neurons is associated with reduced neuromuscular agrin secretion.
Volume: 27
Issue: 8
Pages: 1434-1446
Publication
First Author: Wang B
Year: 2020
Journal: FASEB J
Title: Identification of the downstream molecules of agrin/Dok-7 signaling in muscle.
Volume: 34
Issue: 4
Pages: 5144-5161
Publication
First Author: Linnoila J
Year: 2008
Journal: Neuron
Title: A mammalian homolog of Drosophila tumorous imaginal discs, Tid1, mediates agrin signaling at the neuromuscular junction.
Volume: 60
Issue: 4
Pages: 625-41
Publication
First Author: Zhu D
Year: 2008
Journal: J Neurosci
Title: Muscle-specific receptor tyrosine kinase endocytosis in acetylcholine receptor clustering in response to agrin.
Volume: 28
Issue: 7
Pages: 1688-96
Publication
First Author: Kim ML
Year: 2008
Journal: Mol Cell Neurosci
Title: O-fucosylation of muscle agrin determines its ability to cluster acetylcholine receptors.
Volume: 39
Issue: 3
Pages: 452-64
Publication
First Author: Henriquez JP
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Wnt signaling promotes AChR aggregation at the neuromuscular synapse in collaboration with agrin.
Volume: 105
Issue: 48
Pages: 18812-7
Publication
First Author: Yang J
Year: 2011
Journal: Nat Neurosci
Title: Nestin negatively regulates postsynaptic differentiation of the neuromuscular synapse.
Volume: 14
Issue: 3
Pages: 324-30
Publication
First Author: Zhang Y
Year: 2015
Journal: Eur J Neurosci
Title: Differential regulation of AChR clustering in the polar and equatorial region of murine muscle spindles.
Volume: 41
Issue: 1
Pages: 69-78
Publication
First Author: Kirshenbaum GS
Year: 2012
Journal: Genes Brain Behav
Title: Genetic suppression of agrin reduces mania-like behavior in Na+ , K+ -ATPase α3 mutant mice.
Volume: 11
Issue: 4
Pages: 436-43
Publication
First Author: Hoddevik EH
Year: 2020
Journal: Brain Struct Funct
Title: Organisation of extracellular matrix proteins laminin and agrin in pericapillary basal laminae in mouse brain.
Volume: 225
Issue: 2
Pages: 805-816
Publication
First Author: Gramolini AO
Year: 1998
Journal: J Biol Chem
Title: Muscle and neural isoforms of agrin increase utrophin expression in cultured myotubes via a transcriptional regulatory mechanism.
Volume: 273
Issue: 2
Pages: 736-43
Publication
First Author: Gustafsson E
Year: 2000
Journal: Exp Cell Res
Title: Insights into extracellular matrix functions from mutant mouse models.
Volume: 261
Issue: 1
Pages: 52-68
Publication
First Author: Gee SH
Year: 1994
Journal: Cell
Title: Dystroglycan-alpha, a dystrophin-associated glycoprotein, is a functional agrin receptor.
Volume: 77
Issue: 5
Pages: 675-86
Publication
First Author: Bromann PA
Year: 2004
Journal: Neuroscience
Title: Kinase- and rapsyn-independent activities of the muscle-specific kinase (MuSK).
Volume: 125
Issue: 2
Pages: 417-26