Type |
Details |
Score |
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7482714 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-05-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160331 |
Pattern: |
Punctate |
Stage: |
TS01 |
Assay Id: |
MGI:7482802 |
Age: |
embryonic day 0.5 |
Image: |
4a RAB7 |
Note: |
Punctate expression in periphery of cytoplasm near plasma membrane. |
Specimen Label: |
4a RAB7 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7482714 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-05-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160331 |
Pattern: |
Regionally restricted |
Stage: |
TS01 |
Assay Id: |
MGI:7482802 |
Age: |
embryonic day 0.5 |
Image: |
4b RAB7 |
Note: |
Expression abnormally aggregated in cytoplasm, colocalized with actin. |
Specimen Label: |
4b RAB7 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vitelli R |
Year: |
1995 |
Journal: |
Biochim Biophys Acta |
Title: |
Cloning and expression analysis of the murine Rab7 cDNA. |
Volume: |
1264 |
Issue: |
3 |
Pages: |
268-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yan H |
Year: |
2020 |
Journal: |
J Immunol |
Title: |
B Cell Endosomal RAB7 Promotes TRAF6 K63 Polyubiquitination and NF-κB Activation for Antibody Class-Switching. |
Volume: |
204 |
Issue: |
5 |
Pages: |
1146-1157 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu K |
Year: |
2017 |
Journal: |
J Cell Biol |
Title: |
WDR91 is a Rab7 effector required for neuronal development. |
Volume: |
216 |
Issue: |
10 |
Pages: |
3307-3321 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chiariello M |
Year: |
1998 |
Journal: |
Mamm Genome |
Title: |
Genetic mapping of the mouse Rab7 gene and pseudogene and of the human RAB7 homolog. |
Volume: |
9 |
Issue: |
6 |
Pages: |
448-52 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7464561 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-04-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160518 |
Pattern: |
Not Specified |
Stage: |
TS08 |
Assay Id: |
MGI:7464737 |
Age: |
embryonic day 6.2 |
|
|
Specimen Label: |
6A rab7 WT |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7464561 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-04-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160518 |
Pattern: |
Not Specified |
Stage: |
TS08 |
Assay Id: |
MGI:7464737 |
Age: |
embryonic day 6.2 |
|
|
Specimen Label: |
6A rab7 mVam2-/- |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7464561 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-04-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160518 |
Pattern: |
Not Specified |
Stage: |
TS08 |
Assay Id: |
MGI:7464737 |
Age: |
embryonic day 6.0 |
|
|
Specimen Label: |
S5A rab7 wild-type |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7464561 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-04-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160518 |
Pattern: |
Not Specified |
Stage: |
TS08 |
Assay Id: |
MGI:7464737 |
Age: |
embryonic day 6.0 |
|
|
Specimen Label: |
S5A rab7 mVam2-/- |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7464561 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-04-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160518 |
Pattern: |
Regionally restricted |
Stage: |
TS08 |
Assay Id: |
MGI:7464737 |
Age: |
embryonic day 6.0 |
|
Note: |
Expression in visceral endoderm overlying extraembryonic ectoderm. Expression in apical vacuoles. |
Specimen Label: |
S5C rab7 wild-type |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7464561 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-04-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160518 |
Pattern: |
Regionally restricted |
Stage: |
TS08 |
Assay Id: |
MGI:7464737 |
Age: |
embryonic day 6.0 |
|
Note: |
Expression in visceral endoderm overlying extraembryonic ectoderm. Expression in apical vacuoles. |
Specimen Label: |
S5C rab7 mVam2-/- |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Roque NR |
Year: |
2020 |
Journal: |
Biochim Biophys Acta Mol Cell Biol Lipids |
Title: |
Rab7 controls lipid droplet-phagosome association during mycobacterial infection. |
Volume: |
1865 |
Issue: |
8 |
Pages: |
158703 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
207
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Mizuno K |
Year: |
2003 |
Journal: |
Mol Biol Cell |
Title: |
Rabring7, a novel Rab7 target protein with a RING finger motif. |
Volume: |
14 |
Issue: |
9 |
Pages: |
3741-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Roy SG |
Year: |
2013 |
Journal: |
Autophagy |
Title: |
Reciprocal effects of rab7 deletion in activated and neglected T cells. |
Volume: |
9 |
Issue: |
7 |
Pages: |
1009-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Matsumoto N |
Year: |
2018 |
Journal: |
Sci Rep |
Title: |
Essential Role of the a3 Isoform of V-ATPase in Secretory Lysosome Trafficking via Rab7 Recruitment. |
Volume: |
8 |
Issue: |
1 |
Pages: |
6701 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vitelli R |
Year: |
1996 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Molecular cloning and expression analysis of the human Rab7 GTP-ase complementary deoxyribonucleic acid. |
Volume: |
229 |
Issue: |
3 |
Pages: |
887-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Takahashi K |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
Disruption of Small GTPase Rab7 Exacerbates the Severity of Acute Pancreatitis in Experimental Mouse Models. |
Volume: |
7 |
Issue: |
1 |
Pages: |
2817 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wong YC |
Year: |
2023 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Misregulation of mitochondria-lysosome contact dynamics in Charcot-Marie-Tooth Type 2B disease Rab7 mutant sensory peripheral neurons. |
Volume: |
120 |
Issue: |
44 |
Pages: |
e2313010120 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim JY |
Year: |
2002 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Rab7 gene is up-regulated by cholesterol-rich diet in the liver and artery. |
Volume: |
293 |
Issue: |
1 |
Pages: |
375-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bhattacharya M |
Year: |
2006 |
Journal: |
EMBO J |
Title: |
IL-6 and IL-12 specifically regulate the expression of Rab5 and Rab7 via distinct signaling pathways. |
Volume: |
25 |
Issue: |
12 |
Pages: |
2878-88 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yan CH |
Year: |
2015 |
Journal: |
Biochim Biophys Acta |
Title: |
CREG1 ameliorates myocardial fibrosis associated with autophagy activation and Rab7 expression. |
Volume: |
1852 |
Issue: |
2 |
Pages: |
353-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang J |
Year: |
2017 |
Journal: |
J Biol Chem |
Title: |
Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A. |
Volume: |
292 |
Issue: |
25 |
Pages: |
10328-10346 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pone EJ |
Year: |
2015 |
Journal: |
J Immunol |
Title: |
B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses. |
Volume: |
194 |
Issue: |
7 |
Pages: |
3065-78 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nian FS |
Year: |
2019 |
Journal: |
Mol Neurobiol |
Title: |
Rab18 Collaborates with Rab7 to Modulate Lysosomal and Autophagy Activities in the Nervous System: an Overlapping Mechanism for Warburg Micro Syndrome and Charcot-Marie-Tooth Neuropathy Type 2B. |
Volume: |
56 |
Issue: |
9 |
Pages: |
6095-6105 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nakanishi-Matsui M |
Year: |
2024 |
Journal: |
Biol Pharm Bull |
Title: |
Role of the Cytosolic Domain of the a3 Subunit of V-ATPase in the Interaction with Rab7 and Secretory Lysosome Trafficking in Osteoclasts. |
Volume: |
47 |
Issue: |
1 |
Pages: |
339-344 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fujiwara T |
Year: |
2016 |
Journal: |
JCI Insight |
Title: |
PLEKHM1/DEF8/RAB7 complex regulates lysosome positioning and bone homeostasis. |
Volume: |
1 |
Issue: |
17 |
Pages: |
e86330 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liang W |
Year: |
2023 |
Journal: |
Nat Commun |
Title: |
Mitochondria are secreted in extracellular vesicles when lysosomal function is impaired. |
Volume: |
14 |
Issue: |
1 |
Pages: |
5031 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawamura N |
Year: |
2020 |
Journal: |
Cell Rep |
Title: |
Rab7-Mediated Endocytosis Establishes Patterning of Wnt Activity through Inactivation of Dkk Antagonism. |
Volume: |
31 |
Issue: |
10 |
Pages: |
107733 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawamura N |
Year: |
2012 |
Journal: |
Nat Commun |
Title: |
Delivery of endosomes to lysosomes via microautophagy in the visceral endoderm of mouse embryos. |
Volume: |
3 |
|
Pages: |
1071 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yamaguchi H |
Year: |
2009 |
Journal: |
PLoS Pathog |
Title: |
An initial step of GAS-containing autophagosome-like vacuoles formation requires Rab7. |
Volume: |
5 |
Issue: |
11 |
Pages: |
e1000670 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sugaya K |
Year: |
2011 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Mobility of late endosomal and lysosomal markers on phagosomes analyzed by fluorescence recovery after photobleaching. |
Volume: |
410 |
Issue: |
2 |
Pages: |
371-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Farg MA |
Year: |
2014 |
Journal: |
Hum Mol Genet |
Title: |
C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking. |
Volume: |
23 |
Issue: |
13 |
Pages: |
3579-95 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lizaso A |
Year: |
2013 |
Journal: |
Autophagy |
Title: |
β-adrenergic receptor-stimulated lipolysis requires the RAB7-mediated autolysosomal lipid degradation. |
Volume: |
9 |
Issue: |
8 |
Pages: |
1228-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yap CC |
Year: |
2018 |
Journal: |
J Cell Biol |
Title: |
Degradation of dendritic cargos requires Rab7-dependent transport to somatic lysosomes. |
Volume: |
217 |
Issue: |
9 |
Pages: |
3141-3159 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li L |
Year: |
2017 |
Journal: |
J Cell Sci |
Title: |
Missing-in-metastasis protein downregulates CXCR4 by promoting ubiquitylation and interaction with small Rab GTPases. |
Volume: |
130 |
Issue: |
8 |
Pages: |
1475-1485 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bai L |
Year: |
2021 |
Journal: |
Cell Death Dis |
Title: |
Simvastatin accelerated motoneurons death in SOD1G93A mice through inhibiting Rab7-mediated maturation of late autophagic vacuoles. |
Volume: |
12 |
Issue: |
4 |
Pages: |
392 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sender V |
Year: |
2011 |
Journal: |
J Immunol |
Title: |
Pulmonary surfactant protein A enhances endolysosomal trafficking in alveolar macrophages through regulation of Rab7. |
Volume: |
186 |
Issue: |
4 |
Pages: |
2397-411 |
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kizuka Y |
Year: |
2015 |
Journal: |
EMBO Mol Med |
Title: |
An aberrant sugar modification of BACE1 blocks its lysosomal targeting in Alzheimer's disease. |
Volume: |
7 |
Issue: |
2 |
Pages: |
175-89 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cormont M |
Year: |
2001 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
A FYVE-finger-containing protein, Rabip4, is a Rab4 effector involved in early endosomal traffic. |
Volume: |
98 |
Issue: |
4 |
Pages: |
1637-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yao M |
Year: |
2009 |
Journal: |
J Immunol |
Title: |
Late endosome/lysosome-localized Rab7b suppresses TLR9-initiated proinflammatory cytokine and type I IFN production in macrophages. |
Volume: |
183 |
Issue: |
3 |
Pages: |
1751-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ohbayashi N |
Year: |
2012 |
Journal: |
J Cell Sci |
Title: |
Melanoregulin regulates retrograde melanosome transport through interaction with the RILP-p150Glued complex in melanocytes. |
Volume: |
125 |
Issue: |
Pt 6 |
Pages: |
1508-18 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu JJ |
Year: |
2007 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Retrolinkin, a membrane protein, plays an important role in retrograde axonal transport. |
Volume: |
104 |
Issue: |
7 |
Pages: |
2223-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Guo F |
Year: |
2015 |
Journal: |
J Cell Biochem |
Title: |
Lyar Is a New Ligand for Retinal Pigment Epithelial Phagocytosis. |
Volume: |
116 |
Issue: |
10 |
Pages: |
2177-87 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hirose T |
Year: |
2019 |
Journal: |
J Clin Invest |
Title: |
ATP6AP2 variant impairs CNS development and neuronal survival to cause fulminant neurodegeneration. |
Volume: |
129 |
Issue: |
5 |
Pages: |
2145-2162 |
|
•
•
•
•
•
|
Publication |
First Author: |
Magalhaes J |
Year: |
2016 |
Journal: |
Hum Mol Genet |
Title: |
Autophagic lysosome reformation dysfunction in glucocerebrosidase deficient cells: relevance to Parkinson disease. |
Volume: |
25 |
Issue: |
16 |
Pages: |
3432-3445 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fossale E |
Year: |
2004 |
Journal: |
BMC Neurosci |
Title: |
Membrane trafficking and mitochondrial abnormalities precede subunit c deposition in a cerebellar cell model of juvenile neuronal ceroid lipofuscinosis. |
Volume: |
5 |
|
Pages: |
57 |
|
•
•
•
•
•
|
Publication |
First Author: |
Seaman MN |
Year: |
2004 |
Journal: |
J Cell Biol |
Title: |
Cargo-selective endosomal sorting for retrieval to the Golgi requires retromer. |
Volume: |
165 |
Issue: |
1 |
Pages: |
111-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yokoyama S |
Year: |
2009 |
Journal: |
Dev Cell |
Title: |
A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. |
Volume: |
17 |
Issue: |
6 |
Pages: |
836-48 |
|
•
•
•
•
•
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Publication |
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