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Search results 101 to 180 out of 180 for Ackr2

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0.022s
Type Details Score
GXD Expression  
Probe: MGI:4885393
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267228
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945886
Age: postnatal day 42
Image: g01906 Adult
Specimen Label: g01906 Adult
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4885393
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267328
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945886
Age: postnatal day 42
Image: g01906 Adult
Specimen Label: g01906 Adult
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4885393
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267828
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945886
Age: postnatal day 42
Image: g01906 Adult
Specimen Label: g01906 Adult
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:4885393
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945886
Age: postnatal day 42
Image: g01906 Adult
Note: Expression was region specific and scattered.
Specimen Label: g01906 Adult
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4885393
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945886
Age: postnatal day 42
Image: g01906 Adult
Specimen Label: g01906 Adult
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4885393
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945886
Age: postnatal day 42
Image: g01906 Adult
Specimen Label: g01906 Adult
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:4885393
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945886
Age: postnatal day 42
Image: g01906 Adult
Note: Expression was region specific and scattered.
Specimen Label: g01906 Adult
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4885393
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753628
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945886
Age: postnatal day 42
Image: g01906 Adult
Specimen Label: g01906 Adult
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4885393
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945886
Age: postnatal day 42
Image: g01906 Adult
Specimen Label: g01906 Adult
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4885393
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945886
Age: postnatal day 42
Image: g01906 Adult
Specimen Label: g01906 Adult
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4885393
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945886
Age: postnatal day 42
Image: g01906 Adult
Specimen Label: g01906 Adult
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4885393
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945886
Age: postnatal day 42
Image: g01906 Adult
Specimen Label: g01906 Adult
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4885393
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945886
Age: postnatal day 42
Image: g01906 Adult
Specimen Label: g01906 Adult
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4885393
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945886
Age: postnatal day 42
Image: g01906 Adult
Specimen Label: g01906 Adult
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:7262727
Assay Type: RNA in situ
Annotation Date: 2022-04-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3187722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7262736
Age: embryonic day 14.5
Image: 6Bi/S3A
Specimen Label: 6Bi/S3A
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7262727
Assay Type: RNA in situ
Annotation Date: 2022-04-19
Strength: Absent
Sex: Female
Emaps: EMAPS:3526928
Stage: TS28
Assay Id: MGI:7262736
Age: postnatal
Image: 6Bi decidua
Specimen Label: 6Bi decidua
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:7262727
Assay Type: RNA in situ
Annotation Date: 2022-04-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:7262736
Age: embryonic day 13.5
Image: S3Bi
Specimen Label: S3Bi
Detected: false
Specimen Num: 5
GXD Expression    
Probe: MGI:7262727
Assay Type: RNA in situ
Annotation Date: 2022-04-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:7262736
Age: embryonic day 13.5
Image: S3Bii
Specimen Label: S3Bii
Detected: false
Specimen Num: 6
GXD Expression    
Probe: MGI:7262727
Assay Type: RNA in situ
Annotation Date: 2022-04-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3187722
Stage: TS22
Assay Id: MGI:7262736
Age: embryonic day 14.5
Image: 6BII
Specimen Label: 6BII
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:7262727
Assay Type: RNA in situ
Annotation Date: 2022-04-19
Strength: Absent
Sex: Female
Emaps: EMAPS:3526928
Stage: TS28
Assay Id: MGI:7262736
Age: postnatal
Image: 6Bii decidua
Specimen Label: 6Bii decidua
Detected: false
Specimen Num: 4
Publication    
First Author: Nibbs RJB
Year: 1997
Journal: GenBank Submission
Title: M. musculus mRNA for beta-chemokine receptor D6
Pages: Y12879
Publication
First Author: McKimmie CS
Year: 2009
Journal: Blood
Title: A TLR2 ligand suppresses inflammation by modulation of chemokine receptors and redirection of leukocyte migration.
Volume: 113
Issue: 18
Pages: 4224-31
Publication
First Author: Pabst O
Year: 2004
Journal: J Exp Med
Title: Chemokine receptor CCR9 contributes to the localization of plasma cells to the small intestine.
Volume: 199
Issue: 3
Pages: 411-6
Publication
First Author: Aswad M
Year: 2017
Journal: J Immunol
Title: CCL5 Promotes Resolution-Phase Macrophage Reprogramming in Concert with the Atypical Chemokine Receptor D6 and Apoptotic Polymorphonuclear Cells.
Volume: 199
Issue: 4
Pages: 1393-1404
Publication  
First Author: Hajrasouliha AR
Year: 2013
Journal: Mol Vis
Title: Expression of the chemokine decoy receptor D6 mediates dendritic cell function and promotes corneal allograft rejection.
Volume: 19
Pages: 2517-25
Publication
First Author: Hadeiba H
Year: 2012
Journal: Immunity
Title: Plasmacytoid dendritic cells transport peripheral antigens to the thymus to promote central tolerance.
Volume: 36
Issue: 3
Pages: 438-50
Publication
First Author: McKimmie CS
Year: 2008
Journal: J Immunol
Title: Hemopoietic cell expression of the chemokine decoy receptor D6 is dynamic and regulated by GATA1.
Volume: 181
Issue: 5
Pages: 3353-63
Publication
First Author: Cochain C
Year: 2012
Journal: Arterioscler Thromb Vasc Biol
Title: The chemokine decoy receptor D6 prevents excessive inflammation and adverse ventricular remodeling after myocardial infarction.
Volume: 32
Issue: 9
Pages: 2206-13
Publication
First Author: Loyher PL
Year: 2016
Journal: Cancer Res
Title: CCR2 Influences T Regulatory Cell Migration to Tumors and Serves as a Biomarker of Cyclophosphamide Sensitivity.
Volume: 76
Issue: 22
Pages: 6483-6494
Publication
First Author: Nibbs RJ
Year: 1997
Journal: J Biol Chem
Title: Cloning and characterization of a novel murine beta chemokine receptor, D6. Comparison to three other related macrophage inflammatory protein-1alpha receptors, CCR-1, CCR-3, and CCR-5.
Volume: 272
Issue: 19
Pages: 12495-504
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Allele
Name: atypical chemokine receptor 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Publication
First Author: Zheng X
Year: 2022
Journal: Kidney360
Title: Endothelial Cell-Specific Molecule-1 Inhibits Albuminuria in Diabetic Mice.
Volume: 3
Issue: 12
Pages: 2059-2076
Publication  
First Author: Gowhari Shabgah A
Year: 2022
Journal: Front Immunol
Title: The Role of Atypical Chemokine Receptor D6 (ACKR2) in Physiological and Pathological Conditions; Friend, Foe, or Both?
Volume: 13
Pages: 861931
Publication
First Author: Zou YR
Year: 1998
Journal: Nature
Title: Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development.
Volume: 393
Issue: 6685
Pages: 595-9
Publication
First Author: Kitchen SG
Year: 1997
Journal: J Virol
Title: CXCR4 expression during lymphopoiesis: implications for human immunodeficiency virus type 1 infection of the thymus.
Volume: 71
Issue: 9
Pages: 6928-34
Publication
First Author: Anton PA
Year: 2000
Journal: AIDS
Title: Enhanced levels of functional HIV-1 co-receptors on human mucosal T cells demonstrated using intestinal biopsy tissue.
Volume: 14
Issue: 12
Pages: 1761-5
Publication
First Author: Inngjerdingen M
Year: 2001
Journal: Blood
Title: Expression and regulation of chemokine receptors in human natural killer cells.
Volume: 97
Issue: 2
Pages: 367-75
Publication
First Author: Iikura M
Year: 2001
Journal: J Leukoc Biol
Title: Chemokine receptors in human basophils: inducible expression of functional CXCR4.
Volume: 70
Issue: 1
Pages: 113-20
Publication
First Author: Gupta SK
Year: 1998
Journal: J Biol Chem
Title: Chemokine receptors in human endothelial cells. Functional expression of CXCR4 and its transcriptional regulation by inflammatory cytokines.
Volume: 273
Issue: 7
Pages: 4282-7
Publication
First Author: Lu M
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Abnormal development of the hippocampal dentate gyrus in mice lacking the CXCR4 chemokine receptor.
Volume: 99
Issue: 10
Pages: 7090-5
Publication
First Author: Nie Y
Year: 2008
Journal: J Exp Med
Title: CXCR4 is required for the quiescence of primitive hematopoietic cells.
Volume: 205
Issue: 4
Pages: 777-83
Publication
First Author: Zamarchi R
Year: 2002
Journal: Clin Exp Immunol
Title: Expression and functional activity of CXCR-4 and CCR-5 chemokine receptors in human thymocytes.
Volume: 127
Issue: 2
Pages: 321-30
Publication
First Author: Sun Y
Year: 2002
Journal: J Biol Chem
Title: Beta-arrestin2 is critically involved in CXCR4-mediated chemotaxis, and this is mediated by its enhancement of p38 MAPK activation.
Volume: 277
Issue: 51
Pages: 49212-9
Publication
First Author: Jordan NJ
Year: 1999
Journal: J Clin Invest
Title: Expression of functional CXCR4 chemokine receptors on human colonic epithelial cells.
Volume: 104
Issue: 8
Pages: 1061-9
Protein Domain
Type: Family
Description: CXC chemokine receptor 4 (CXCR4), also known as fusin, which is a specific receptor for a CXCL12 (or SDF1). CXCR4 has a wide cellular distribution, with expression on most immature and mature hematopoietic cell types [, , , , ]. In addition, CXCR4 can also be found on vascular endothelial cells and neuronal/nerve cells []. Upon binding to CXCR4, CXCL12 causes mobilisation of intracellular calcium and chemotaxis [, , ]. CXCL12 is known to be important in hematopoietic stem cell homing to the bone marrow and in hematopoietic stem cell quiescence. CXCR4 has a rather broad activity, and has been linked to cardiac, cerebellar gastric vasculature development [, ]and to hematopoiesis []. Atypical chemokine receptor 2 (ACKR2/D6) []is a chemokine-scavenging receptor or chemokine decoy receptor. It is capable of internalising and effectively scavenging its ligands through beta-arrestin-dependent activation of the cofilin pathway [, ]. ACKR2 is highly promiscuous and can bin the majority of (if not all) inflammatory CC-chemokines []. It plays an essential role in the resolution of the inflammatory response [, , ]. Although it lacks the canonical DRYLAIV motif necessary for classical signalling, ACKR2/D6 may be involved in 'atypical' signaling pathways downstream of ligand binding []. It has been shown to be involved in regulating vessel density [].
Protein
Organism: Mus musculus/domesticus
Length: 128  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 272  
Fragment?: true
Publication
First Author: Huber TB
Year: 2002
Journal: J Immunol
Title: Expression of functional CCR and CXCR chemokine receptors in podocytes.
Volume: 168
Issue: 12
Pages: 6244-52
Protein
Organism: Mus musculus/domesticus
Length: 359  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 359  
Fragment?: false