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Search results 2501 to 2600 out of 3083 for Lepr

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Type Details Score
Publication
25698262 | J:220710
First Author: Fujita H
Year: 2015
Journal: EMBO J
Title: The E3 ligase synoviolin controls body weight and mitochondrial biogenesis through negative regulation of PGC-1β.
Volume: 34
Issue: 8
Pages: 1042-55
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Publication
31217420 | J:277932
First Author: Mitrofanova A
Year: 2019
Journal: Nat Commun
Title: SMPDL3b modulates insulin receptor signaling in diabetic kidney disease.
Volume: 10
Issue: 1
Pages: 2692
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Publication
30807826 | J:281485
 
First Author: Griggs RB
Year: 2019
Journal: Neurobiol Dis
Title: Methylglyoxal and a spinal TRPA1-AC1-Epac cascade facilitate pain in the db/db mouse model of type 2 diabetes.
Volume: 127
Pages: 76-86
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Publication
26935695 | J:229664
First Author: Beyaz S
Year: 2016
Journal: Nature
Title: High-fat diet enhances stemness and tumorigenicity of intestinal progenitors.
Volume: 531
Issue: 7592
Pages: 53-8
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Publication
21459326 | J:172245
First Author: Villanueva CJ
Year: 2011
Journal: Cell Metab
Title: TLE3 is a dual-function transcriptional coregulator of adipogenesis.
Volume: 13
Issue: 4
Pages: 413-427
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Publication
28957638 | J:271487
First Author: Mathews JA
Year: 2018
Journal: Am J Respir Cell Mol Biol
Title: Augmented Responses to Ozone in Obese Mice Require IL-17A and Gastrin-Releasing Peptide.
Volume: 58
Issue: 3
Pages: 341-351
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Publication
34262177 | J:334858
First Author: Berrios J
Year: 2021
Journal: Nature
Title: Food cue regulation of AGRP hunger neurons guides learning.
Volume: 595
Issue: 7869
Pages: 695-700
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Publication
26411686 | J:269852
First Author: Kim JG
Year: 2015
Journal: Cell Rep
Title: AgRP Neurons Regulate Bone Mass.
Volume: 13
Issue: 1
Pages: 8-14
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Publication
31978605 | J:292718
 
First Author: Thebeau C
Year: 2020
Journal: Neurobiol Dis
Title: Light deprivation reduces the severity of experimental diabetic retinopathy.
Volume: 137
Pages: 104754
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Publication
28325833 | J:242771
First Author: Fukuda S
Year: 2017
Journal: J Biol Chem
Title: The unique prodomain of T-cadherin plays a key role in adiponectin binding with the essential extracellular cadherin repeats 1 and 2.
Volume: 292
Issue: 19
Pages: 7840-7849
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Publication
12438645 | J:125584
First Author: Picard F
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Progesterone receptor knockout mice have an improved glucose homeostasis secondary to beta -cell proliferation.
Volume: 99
Issue: 24
Pages: 15644-8
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Publication
23447682 | J:194839
First Author: Yu Y
Year: 2013
Journal: J Immunol
Title: Cutting edge: Leptin-induced RORγt expression in CD4+ T cells promotes Th17 responses in systemic lupus erythematosus.
Volume: 190
Issue: 7
Pages: 3054-8
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Publication
21737546 | J:179350
First Author: Cheng H
Year: 2011
Journal: J Am Soc Nephrol
Title: Podocyte COX-2 exacerbates diabetic nephropathy by increasing podocyte (pro)renin receptor expression.
Volume: 22
Issue: 7
Pages: 1240-51
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Publication
30024858 | J:266922
First Author: Liles JT
Year: 2018
Journal: J Clin Invest
Title: ASK1 contributes to fibrosis and dysfunction in models of kidney disease.
Volume: 128
Issue: 10
Pages: 4485-4500
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Publication
24531551 | J:209728
First Author: Khan S
Year: 2014
Journal: J Clin Invest
Title: Lipotoxic disruption of NHE1 interaction with PI(4,5)P2 expedites proximal tubule apoptosis.
Volume: 124
Issue: 3
Pages: 1057-68
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Publication
23760291 | J:282748
First Author: Miyazawa T
Year: 2013
Journal: Kidney Int
Title: Low nitric oxide bioavailability upregulates renal heparin binding EGF-like growth factor expression.
Volume: 84
Issue: 6
Pages: 1176-88
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Publication
29654303 | J:263120
First Author: Zhao XP
Year: 2018
Journal: Sci Rep
Title: Hedgehog Interacting Protein Promotes Fibrosis and Apoptosis in Glomerular Endothelial Cells in Murine Diabetes.
Volume: 8
Issue: 1
Pages: 5958
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Publication
23541372 | J:299563
First Author: Harlan SM
Year: 2013
Journal: Cell Metab
Title: Hypothalamic mTORC1 signaling controls sympathetic nerve activity and arterial pressure and mediates leptin effects.
Volume: 17
Issue: 4
Pages: 599-606
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27757953 | J:241733
First Author: Lau JK
Year: 2017
Journal: J Pathol
Title: Animal models of non-alcoholic fatty liver disease: current perspectives and recent advances.
Volume: 241
Issue: 1
Pages: 36-44
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Publication
31624901 | J:282750
First Author: Bensellam M
Year: 2019
Journal: Diabetologia
Title: Metallothionein 1 negatively regulates glucose-stimulated insulin secretion and is differentially expressed in conditions of beta cell compensation and failure in mice and humans.
Volume: 62
Issue: 12
Pages: 2273-2286
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Publication
29311632 | J:260174
First Author: Meakin PJ
Year: 2018
Journal: Sci Rep
Title: Bace1-dependent amyloid processing regulates hypothalamic leptin sensitivity in obese mice.
Volume: 8
Issue: 1
Pages: 55
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Publication
25003192 | J:213849
First Author: Lu Y
Year: 2014
Journal: J Clin Invest
Title: Periostin promotes liver steatosis and hypertriglyceridemia through downregulation of PPARα.
Volume: 124
Issue: 8
Pages: 3501-13
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Publication
21346174 | J:171758
First Author: Kim W
Year: 2011
Journal: Diabetes
Title: Cannabinoids inhibit insulin receptor signaling in pancreatic β-cells.
Volume: 60
Issue: 4
Pages: 1198-209
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Publication
11298451 | J:68834
First Author: Di Marzo V
Year: 2001
Journal: Nature
Title: Leptin-regulated endocannabinoids are involved in maintaining food intake.
Volume: 410
Issue: 6830
Pages: 822-5
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22167524 | J:184649
First Author: Lynch CJ
Year: 2012
Journal: Am J Physiol Endocrinol Metab
Title: Some cannabinoid receptor ligands and their distomers are direct-acting openers of SUR1 K(ATP) channels.
Volume: 302
Issue: 5
Pages: E540-51
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Publication
18840364 | J:143422
First Author: Banks AS
Year: 2008
Journal: Cell Metab
Title: SirT1 gain of function increases energy efficiency and prevents diabetes in mice.
Volume: 8
Issue: 4
Pages: 333-41
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Publication
24813890 | J:211797
First Author: Gonçalves GH
Year: 2014
Journal: Cell Rep
Title: Hypothalamic agouti-related peptide neurons and the central melanocortin system are crucial mediators of leptin's antidiabetic actions.
Volume: 7
Issue: 4
Pages: 1093-103
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Publication
29535089 | J:262210
First Author: Allison MB
Year: 2018
Journal: Diabetes
Title: Defining the Transcriptional Targets of Leptin Reveals a Role for Atf3 in Leptin Action.
Volume: 67
Issue: 6
Pages: 1093-1104
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Publication
27571135 | J:240442
First Author: Odle AK
Year: 2016
Journal: Endocrinology
Title: A Sex-Dependent, Tropic Role for Leptin in the Somatotrope as a Regulator of POU1F1 and POU1F1-Dependent Hormones.
Volume: 157
Issue: 10
Pages: 3958-3971
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Publication
23417423 | J:196705
First Author: Syed M
Year: 2013
Journal: Endocrinology
Title: Ghrelin restoration of function in vitro in somatotropes from male mice lacking the Janus kinase (JAK)-binding site of the leptin receptor.
Volume: 154
Issue: 4
Pages: 1565-76
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Publication
21829168 | J:179942
First Author: Yu X
Year: 2011
Journal: EMBO J
Title: Egr-1 decreases adipocyte insulin sensitivity by tilting PI3K/Akt and MAPK signal balance in mice.
Volume: 30
Issue: 18
Pages: 3754-65
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Publication
17202473 | J:117213
First Author: Münzberg H
Year: 2007
Journal: J Neurosci
Title: Appropriate inhibition of orexigenic hypothalamic arcuate nucleus neurons independently of leptin receptor/STAT3 signaling.
Volume: 27
Issue: 1
Pages: 69-74
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Publication
15995171 | J:100492
First Author: Gruen ML
Year: 2005
Journal: J Lipid Res
Title: Persistence of high density lipoprotein particles in obese mice lacking apolipoprotein A-I.
Volume: 46
Issue: 9
Pages: 2007-14
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Publication
14675208 | J:120040
First Author: Kämpfer H
Year: 2003
Journal: J Invest Dermatol
Title: Expression and activity of arginase isoenzymes during normal and diabetes-impaired skin repair.
Volume: 121
Issue: 6
Pages: 1544-51
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Publication
30905621 | J:275503
First Author: Chen CH
Year: 2019
Journal: Biochim Biophys Acta Gen Subj
Title: O-GlcNAcylation disrupts STRA6-retinol signals in kidneys of diabetes.
Volume: 1863
Issue: 6
Pages: 1059-1069
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Publication
35298439 | J:324469
 
First Author: Mugabo Y
Year: 2022
Journal: JCI Insight
Title: 14-3-3ζ Constrains insulin secretion by regulating mitochondrial function in pancreatic β cells.
Volume: 7
Issue: 8
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Publication
33065162 | J:299873
 
First Author: Shin SJ
Year: 2020
Journal: Metabolism
Title: Disruption of retinoid homeostasis induces RBP4 overproduction in diabetes: O-GlcNAcylation involved.
Volume: 113
Pages: 154403
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Publication
9177239 | J:40976
First Author: Gloaguen I
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Ciliary neurotrophic factor corrects obesity and diabetes associated with leptin deficiency and resistance.
Volume: 94
Issue: 12
Pages: 6456-61
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Publication
20413511 | J:169354
First Author: Kaiyala KJ
Year: 2010
Journal: Diabetes
Title: Identification of body fat mass as a major determinant of metabolic rate in mice.
Volume: 59
Issue: 7
Pages: 1657-66
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Publication
33206596 | J:298897
   
First Author: Biddinger JE
Year: 2020
Journal: Elife
Title: Leptin suppresses development of GLP-1 inputs to the paraventricular nucleus of the hypothalamus.
Volume: 9
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Publication
22904304 | J:189915
First Author: Procaccini C
Year: 2012
Journal: J Immunol
Title: Leptin-induced mTOR activation defines a specific molecular and transcriptional signature controlling CD4+ effector T cell responses.
Volume: 189
Issue: 6
Pages: 2941-53
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Publication
10497230 | J:57965
First Author: Berk PD
Year: 1999
Journal: J Biol Chem
Title: Selective up-regulation of fatty acid uptake by adipocytes characterizes both genetic and diet-induced obesity in rodents.
Volume: 274
Issue: 40
Pages: 28626-31
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Publication
23416070 | J:198161
First Author: von Meyenn F
Year: 2013
Journal: Cell Metab
Title: Glucagon-induced acetylation of Foxa2 regulates hepatic lipid metabolism.
Volume: 17
Issue: 3
Pages: 436-47
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Publication
5059196 | J:5253
First Author: Johnson PR
Year: 1972
Journal: J Lipid Res
Title: Cellularity of adipose depots in six strains of genetically obese mice.
Volume: 13
Issue: 1
Pages: 2-11
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Publication
15358114 | J:91738
First Author: Xu N
Year: 2004
Journal: Biochem Biophys Res Commun
Title: Both leptin and leptin-receptor are essential for apolipoprotein M expression in vivo.
Volume: 321
Issue: 4
Pages: 916-21
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Publication
9519731 | J:45531
First Author: Mizuno TM
Year: 1998
Journal: Diabetes
Title: Hypothalamic pro-opiomelanocortin mRNA is reduced by fasting and [corrected] in ob/ob and db/db mice, but is stimulated by leptin.
Volume: 47
Issue: 2
Pages: 294-7
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Publication
17686962 | J:145120
First Author: Kümpers P
Year: 2007
Journal: Am J Physiol Renal Physiol
Title: Leptin is a coactivator of TGF-beta in unilateral ureteral obstructive kidney disease.
Volume: 293
Issue: 4
Pages: F1355-62
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Publication
26324179 | J:246165
First Author: Liu Y
Year: 2015
Journal: Diabetes
Title: Protein Inhibitor of Activated STAT 1 (PIAS1) Protects Against Obesity-Induced Insulin Resistance by Inhibiting Inflammation Cascade in Adipose Tissue.
Volume: 64
Issue: 12
Pages: 4061-74
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Publication
30243722 | J:270296
First Author: Xu L
Year: 2018
Journal: Biochem Biophys Res Commun
Title: DNA-binding activity of STAT3 increased in hypothalamus of DIO mice; the reduction of STAT3 phosphorylation may facilitate leptin signaling.
Volume: 505
Issue: 1
Pages: 229-235
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Publication
15256362 | J:96143
First Author: Sahai A
Year: 2004
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Obese and diabetic db/db mice develop marked liver fibrosis in a model of nonalcoholic steatohepatitis: role of short-form leptin receptors and osteopontin.
Volume: 287
Issue: 5
Pages: G1035-43
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Publication
17561514 | J:124801
First Author: Sabeva NS
Year: 2007
Journal: J Biol Chem
Title: Defects in the leptin axis reduce abundance of the ABCG5-ABCG8 sterol transporter in liver.
Volume: 282
Issue: 31
Pages: 22397-405
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Publication
24506866 | J:210653
First Author: Sawada N
Year: 2014
Journal: Cell Metab
Title: Endothelial PGC-1α mediates vascular dysfunction in diabetes.
Volume: 19
Issue: 2
Pages: 246-58
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Publication
834144 | J:5759
First Author: Herberg L
Year: 1977
Journal: Metabolism
Title: Laboratory animals exhibiting obesity and diabetes syndromes.
Volume: 26
Issue: 1
Pages: 59-99
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Publication
19468077 | J:149667
First Author: Shafrir E
Year: 2009
Journal: Am J Physiol Endocrinol Metab
Title: A useful list of spontaneously arising animal models of obesity and diabetes.
Volume: 296
Issue: 6
Pages: E1450-2
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Publication
18029445 | J:133332
First Author: Atkinson RD
Year: 2008
Journal: Am J Physiol Endocrinol Metab
Title: Macrophage-derived apolipoprotein E ameliorates dyslipidemia and atherosclerosis in obese apolipoprotein E-deficient mice.
Volume: 294
Issue: 2
Pages: E284-90
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Publication
8621612 | J:33332
First Author: Collins S
Year: 1996
Journal: J Biol Chem
Title: Pharmacologic manipulation of ob expression in a dietary model of obesity.
Volume: 271
Issue: 16
Pages: 9437-40
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25576055 | J:249436
First Author: Chen Y
Year: 2015
Journal: Diabetes
Title: Enhancement of hypothalamic STAT3 acetylation by nuclear receptor Nur77 dictates leptin sensitivity.
Volume: 64
Issue: 6
Pages: 2069-81
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Publication
34622154 | J:314446
First Author: Yau B
Year: 2021
Journal: iScience
Title: Proteomic pathways to metabolic disease and type 2 diabetes in the pancreatic islet.
Volume: 24
Issue: 10
Pages: 103099
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Publication
9254055 | J:41954
First Author: Li X
Year: 1997
Journal: J Lipid Res
Title: Obesity in db and ob animals leads to impaired hepatic very low density lipoprotein secretion and differential secretion of apolipoprotein B-48 and B-100.
Volume: 38
Issue: 7
Pages: 1277-88
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Publication
15181014 | J:121205
First Author: Shi H
Year: 2004
Journal: J Biol Chem
Title: Suppressor of cytokine signaling 3 is a physiological regulator of adipocyte insulin signaling.
Volume: 279
Issue: 33
Pages: 34733-40
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24166765 | J:203061
First Author: Gao Y
Year: 2014
Journal: Glia
Title: Hormones and diet, but not body weight, control hypothalamic microglial activity.
Volume: 62
Issue: 1
Pages: 17-25
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19036876 | J:158084
First Author: Gerin I
Year: 2009
Journal: Endocrinology
Title: Hyperphagia and obesity in female mice lacking tissue inhibitor of metalloproteinase-1.
Volume: 150
Issue: 4
Pages: 1697-704
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Publication
18583460 | J:141913
First Author: Zyromski NJ
Year: 2008
Journal: Am J Physiol Gastrointest Liver Physiol
Title: A murine model of obesity implicates the adipokine milieu in the pathogenesis of severe acute pancreatitis.
Volume: 295
Issue: 3
Pages: G552-8
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Publication
38145825 | J:344205
 
First Author: Liu C
Year: 2024
Journal: Metabolism
Title: TOX3 deficiency mitigates hyperglycemia by suppressing hepatic gluconeogenesis through FoxO1.
Volume: 152
Pages: 155766
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Publication
23736543 | J:203210
First Author: Nakahara K
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: Characterization of a novel genetically obese mouse model demonstrating early onset hyperphagia and hyperleptinemia.
Volume: 305
Issue: 3
Pages: E451-63
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Publication
31296846 | J:285944
First Author: Pham DD
Year: 2019
Journal: Cell Death Dis
Title: Caspase-2 and p75 neurotrophin receptor (p75NTR) are involved in the regulation of SREBP and lipid genes in hepatocyte cells.
Volume: 10
Issue: 7
Pages: 537
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Publication
14981264 | J:88651
First Author: Xu J
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: The voltage-gated potassium channel Kv1.3 regulates peripheral insulin sensitivity.
Volume: 101
Issue: 9
Pages: 3112-7
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Publication
17347480 | J:133914
First Author: Zhang LL
Year: 2007
Journal: Circ Res
Title: Activation of transient receptor potential vanilloid type-1 channel prevents adipogenesis and obesity.
Volume: 100
Issue: 7
Pages: 1063-70
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Publication
19940178 | J:158472
First Author: Hawke Z
Year: 2009
Journal: J Neurosci
Title: PACAP neurons in the hypothalamic ventromedial nucleus are targets of central leptin signaling.
Volume: 29
Issue: 47
Pages: 14828-35
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Publication
9037192 | J:38333
First Author: Mercer JG
Year: 1997
Journal: FEBS Lett
Title: Regulation of leptin receptor and NPY gene expression in hypothalamus of leptin-treated obese (ob/ob) and cold-exposed lean mice.
Volume: 402
Issue: 2-3
Pages: 185-8
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Publication
26552046 | J:228070
First Author: Dominguez Rieg JA
Year: 2016
Journal: Lab Invest
Title: Regulation of intestinal SGLT1 by catestatin in hyperleptinemic type 2 diabetic mice.
Volume: 96
Issue: 1
Pages: 98-111
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Publication
28585545 | J:250329
 
First Author: Axelsson AS
Year: 2017
Journal: Nat Commun
Title: Sox5 regulates beta-cell phenotype and is reduced in type 2 diabetes.
Volume: 8
Pages: 15652
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Publication
22581287 | J:187458
First Author: Sheng L
Year: 2012
Journal: Nat Med
Title: NF-κB–inducing kinase (NIK) promotes hyperglycemia and glucose intolerance in obesity by augmenting glucagon action.
Volume: 18
Issue: 6
Pages: 943-9
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Publication
24394757 | J:211951
First Author: Crépin D
Year: 2014
Journal: Mol Cell Endocrinol
Title: The over-expression of miR-200a in the hypothalamus of ob/ob mice is linked to leptin and insulin signaling impairment.
Volume: 384
Issue: 1-2
Pages: 1-11
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Publication
29522093 | J:260503
First Author: Pan W
Year: 2018
Journal: Endocrinology
Title: Essential Role for Hypothalamic Calcitonin Receptor‒Expressing Neurons in the Control of Food Intake by Leptin.
Volume: 159
Issue: 4
Pages: 1860-1872
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Publication
33688917 | J:322177
 
First Author: Wu L
Year: 2021
Journal: J Exp Med
Title: Hepatic Gadd45β promotes hyperglycemia and glucose intolerance through DNA demethylation of PGC-1α.
Volume: 218
Issue: 5
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Publication
27445662 | J:310541
 
First Author: Senzacqua M
Year: 2016
Journal: Front Neurosci
Title: Action of Administered Ciliary Neurotrophic Factor on the Mouse Dorsal Vagal Complex.
Volume: 10
Pages: 289
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16339484 | J:118064
First Author: Barouch LA
Year: 2006
Journal: Circ Res
Title: Cardiac myocyte apoptosis is associated with increased DNA damage and decreased survival in murine models of obesity.
Volume: 98
Issue: 1
Pages: 119-24
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Publication
37154299 | J:344976
First Author: Liu N
Year: 2023
Journal: EMBO Rep
Title: Hepatic ZBTB22 promotes hyperglycemia and insulin resistance via PEPCK1-driven gluconeogenesis.
Volume: 24
Issue: 6
Pages: e56390
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Publication
35029277 | J:343025
First Author: Hu Q
Year: 2022
Journal: Diabetes
Title: Obesity-Induced miR-455 Upregulation Promotes Adaptive Pancreatic β-Cell Proliferation Through the CPEB1/CDKN1B Pathway.
Volume: 71
Issue: 3
Pages: 394-411
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Publication
21145759 | J:167293
First Author: Procaccini C
Year: 2010
Journal: Immunity
Title: An oscillatory switch in mTOR kinase activity sets regulatory T cell responsiveness.
Volume: 33
Issue: 6
Pages: 929-41
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Publication
19188430 | J:151130
First Author: Narvekar P
Year: 2009
Journal: Diabetes
Title: Liver-specific loss of lipolysis-stimulated lipoprotein receptor triggers systemic hyperlipidemia in mice.
Volume: 58
Issue: 5
Pages: 1040-9
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Publication
12193546 | J:81463
First Author: Ariyasu H
Year: 2002
Journal: Endocrinology
Title: Delayed short-term secretory regulation of ghrelin in obese animals: evidenced by a specific RIA for the active form of ghrelin.
Volume: 143
Issue: 9
Pages: 3341-50
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Publication
17095713 | J:135034
First Author: Bodary PF
Year: 2007
Journal: Arterioscler Thromb Vasc Biol
Title: Leptin regulates neointima formation after arterial injury through mechanisms independent of blood pressure and the leptin receptor/STAT3 signaling pathways involved in energy balance.
Volume: 27
Issue: 1
Pages: 70-6
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Publication
30898698 | J:290876
 
First Author: Zhang B
Year: 2019
Journal: Gene
Title: Long noncoding RNA Mirt2 upregulates USP10 expression to suppress hepatic steatosis by sponging miR-34a-5p.
Volume: 700
Pages: 139-148
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Publication
37402735 | J:337832
First Author: Flaherty SE 3rd
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