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Search results 1 to 100 out of 806 for Ins1

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Category: Publication
Type Details Score
Publication
First Author: Murakami-Kawaguchi S
Year: 2014
Journal: Cell Tissue Res
Title: Expression of Ins1 and Ins2 genes in mouse fetal liver.
Volume: 355
Issue: 2
Pages: 303-14
Publication
First Author: Cheng Y
Year: 2015
Journal: Endocrinology
Title: Generation and Characterization of Transgenic Mice Expressing Mouse Ins1 Promoter for Pancreatic β-Cell-Specific Gene Overexpression and Knockout.
Volume: 156
Issue: 7
Pages: 2724-31
Publication
First Author: Deltour L
Year: 2004
Journal: Gene Expr Patterns
Title: Differential expression and imprinting status of Ins1 and Ins2 genes in extraembryonic tissues of laboratory mice.
Volume: 5
Issue: 2
Pages: 297-300
Publication  
First Author: Leroux L
Year: 2001
Journal: Diabetes
Title: Compensatory responses in mice carrying a null mutation for Ins1 or Ins2.
Volume: 50 Suppl 1
Pages: S150-3
Publication  
First Author: Skovsø S
Year: 2022
Journal: Endocrinology
Title: β-Cell Cre Expression and Reduced Ins1 Gene Dosage Protect Mice From Type 1 Diabetes.
Volume: 163
Issue: 11
Publication
First Author: Babaya N
Year: 2006
Journal: Diabetologia
Title: A new model of insulin-deficient diabetes: male NOD mice with a single copy of Ins1 and no Ins2.
Volume: 49
Issue: 6
Pages: 1222-8
Publication
First Author: Noguchi H
Year: 2021
Journal: Sci Rep
Title: In vivo evaluation of GG2-GG1/A2 element activity in the insulin promoter region using the CRISPR-Cas9 system.
Volume: 11
Issue: 1
Pages: 20290
Publication
First Author: Mehran AE
Year: 2012
Journal: Cell Metab
Title: Hyperinsulinemia drives diet-induced obesity independently of brain insulin production.
Volume: 16
Issue: 6
Pages: 723-37
Publication
First Author: Templeman NM
Year: 2017
Journal: Cell Rep
Title: Reduced Circulating Insulin Enhances Insulin Sensitivity in Old Mice and Extends Lifespan.
Volume: 20
Issue: 2
Pages: 451-463
Publication
First Author: Hasegawa Y
Year: 2016
Journal: Exp Anim
Title: Generation of CRISPR/Cas9-mediated bicistronic knock-in ins1-cre driver mice.
Volume: 65
Issue: 3
Pages: 319-27
Publication
First Author: Deltour L
Year: 1995
Journal: Dev Biol
Title: Tissue- and developmental stage-specific imprinting of the mouse proinsulin gene, Ins2.
Volume: 168
Issue: 2
Pages: 686-8
Publication
First Author: Noguchi H
Year: 2020
Journal: Commun Biol
Title: Mutations in the C1 element of the insulin promoter lead to diabetic phenotypes in homozygous mice.
Volume: 3
Issue: 1
Pages: 309
Publication
First Author: Tvrdik P
Year: 1999
Journal: J Biol Chem
Title: Cig30 and Pitx3 genes are arranged in a partially overlapping tail-to-tail array resulting in complementary transcripts.
Volume: 274
Issue: 37
Pages: 26387-92
Publication  
First Author: Mosleh E
Year: 2020
Journal: Endocrinology
Title: Ins1-Cre and Ins1-CreER Gene Replacement Alleles Are Susceptible To Silencing By DNA Hypermethylation.
Volume: 161
Issue: 8
Publication
First Author: Semplici F
Year: 2016
Journal: Diabetologia
Title: Cell type-specific deletion in mice reveals roles for PAS kinase in insulin and glucagon production.
Volume: 59
Issue: 9
Pages: 1938-47
Publication
First Author: Abdellatif AM
Year: 2015
Journal: Exp Anim
Title: Role of large MAF transcription factors in the mouse endocrine pancreas.
Volume: 64
Issue: 3
Pages: 305-12
Publication
First Author: Liu D
Year: 2022
Journal: Diabetes
Title: YY1 Regulates Glucose Homeostasis Through Controlling Insulin Transcription in Pancreatic β-Cells.
Volume: 71
Issue: 5
Pages: 961-977
Publication
First Author: Fan Y
Year: 2009
Journal: EMBO J
Title: Thymus-specific deletion of insulin induces autoimmune diabetes.
Volume: 28
Issue: 18
Pages: 2812-24
Publication
First Author: Nguyen-Tu MS
Year: 2018
Journal: J Biol Chem
Title: Transcription factor-7-like 2 (TCF7L2) gene acts downstream of the Lkb1/Stk11 kinase to control mTOR signaling, β cell growth, and insulin secretion.
Volume: 293
Issue: 36
Pages: 14178-14189
Publication
First Author: Thorens B
Year: 2015
Journal: Diabetologia
Title: Ins1(Cre) knock-in mice for beta cell-specific gene recombination.
Volume: 58
Issue: 3
Pages: 558-65
Publication
First Author: Duvillié B
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Phenotypic alterations in insulin-deficient mutant mice.
Volume: 94
Issue: 10
Pages: 5137-40
Publication  
First Author: Ramzy A
Year: 2022
Journal: Endocrinology
Title: Insulin Null β-cells Have a Prohormone Processing Defect That Is Not Reversed by AAV Rescue of Proinsulin Expression.
Volume: 163
Issue: 6
Publication
First Author: Hennings TG
Year: 2018
Journal: Endocrinology
Title: In Vivo Deletion of β-Cell Drp1 Impairs Insulin Secretion Without Affecting Islet Oxygen Consumption.
Volume: 159
Issue: 9
Pages: 3245-3256
Publication
First Author: Liu S
Year: 2020
Journal: Diabetes
Title: Adipose Triglyceride Lipase Is a Key Lipase for the Mobilization of Lipid Droplets in Human β-Cells and Critical for the Maintenance of Syntaxin 1a Levels in β-Cells.
Volume: 69
Issue: 6
Pages: 1178-1192
Publication
First Author: Abdellatif AM
Year: 2016
Journal: PLoS One
Title: β-Cell-Specific Mafk Overexpression Impairs Pancreatic Endocrine Cell Development.
Volume: 11
Issue: 2
Pages: e0150010
Publication
First Author: Templeman NM
Year: 2015
Journal: Diabetologia
Title: Suppression of hyperinsulinaemia in growing female mice provides long-term protection against obesity.
Volume: 58
Issue: 10
Pages: 2392-402
Publication
First Author: Templeman NM
Year: 2016
Journal: PLoS One
Title: Hyper-Variability in Circulating Insulin, High Fat Feeding Outcomes, and Effects of Reducing Ins2 Dosage in Male Ins1-Null Mice in a Specific Pathogen-Free Facility.
Volume: 11
Issue: 4
Pages: e0153280
Publication  
First Author: Carrat GR
Year: 2020
Journal: Mol Metab
Title: The type 2 diabetes gene product STARD10 is a phosphoinositide-binding protein that controls insulin secretory granule biogenesis.
Volume: 40
Pages: 101015
Publication
First Author: D'souza AM
Year: 2017
Journal: Mol Metab
Title: Restoration of Lepr in β cells of Lepr null mice does not prevent hyperinsulinemia and hyperglycemia.
Volume: 6
Issue: 6
Pages: 585-593
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Collin GB
Year: 2005
Journal: Hum Mol Genet
Title: Alms1-disrupted mice recapitulate human Alström syndrome.
Volume: 14
Issue: 16
Pages: 2323-33
Publication
First Author: Lalioti V
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: The atypical kinase Cdk5 is activated by insulin, regulates the association between GLUT4 and E-Syt1, and modulates glucose transport in 3T3-L1 adipocytes.
Volume: 106
Issue: 11
Pages: 4249-53
Publication
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
Publication
First Author: Suriyapperuma SP
Year: 2000
Journal: Mamm Genome
Title: The mouse adducin gene family: alternative splicing and chromosomal localization.
Volume: 11
Issue: 1
Pages: 16-23
Publication
First Author: Clee SM
Year: 2006
Journal: Nat Genet
Title: Positional cloning of Sorcs1, a type 2 diabetes quantitative trait locus.
Volume: 38
Issue: 6
Pages: 688-93
Publication
First Author: Ko MS
Year: 1994
Journal: Mamm Genome
Title: Genetic mapping of 40 cDNA clones on the mouse genome by PCR.
Volume: 5
Issue: 6
Pages: 349-55
Publication
First Author: Horn S
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Mind bomb 1 is required for pancreatic β-cell formation.
Volume: 109
Issue: 19
Pages: 7356-61
Publication
First Author: Ursino GM
Year: 2020
Journal: EMBO Rep
Title: ABCA12 regulates insulin secretion from β-cells.
Volume: 21
Issue: 3
Pages: e48692
Publication
First Author: Sano H
Year: 2011
Journal: J Biol Chem
Title: Insulin-stimulated GLUT4 protein translocation in adipocytes requires the Rab10 guanine nucleotide exchange factor Dennd4C.
Volume: 286
Issue: 19
Pages: 16541-5
Publication
First Author: Wentworth BM
Year: 1986
Journal: J Mol Evol
Title: Characterization of the two nonallelic genes encoding mouse preproinsulin.
Volume: 23
Issue: 4
Pages: 305-12
Publication
First Author: Sawa T
Year: 1990
Journal: J Mol Endocrinol
Title: Molecular cloning and DNA sequence analysis of preproinsulin genes in the NON mouse, an animal model of human non-obese, non-insulin-dependent diabetes mellitus.
Volume: 5
Issue: 1
Pages: 61-7
Publication
First Author: Harrison KA
Year: 1999
Journal: Nat Genet
Title: Pancreas dorsal lobe agenesis and abnormal islets of Langerhans in Hlxb9-deficient mice.
Volume: 23
Issue: 1
Pages: 71-5
Publication
First Author: Westmoreland JJ
Year: 2009
Journal: Dev Biol
Title: Pdk1 activity controls proliferation, survival, and growth of developing pancreatic cells.
Volume: 334
Issue: 1
Pages: 285-98
Publication
First Author: Rausa F
Year: 1997
Journal: Dev Biol
Title: The cut-homeodomain transcriptional activator HNF-6 is coexpressed with its target gene HNF-3 beta in the developing murine liver and pancreas.
Volume: 192
Issue: 2
Pages: 228-46
Publication
First Author: Artner I
Year: 2006
Journal: Diabetes
Title: MafB: an activator of the glucagon gene expressed in developing islet alpha- and beta-cells.
Volume: 55
Issue: 2
Pages: 297-304
Publication
First Author: Artner I
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: MafB is required for islet beta cell maturation.
Volume: 104
Issue: 10
Pages: 3853-8
Publication
First Author: Nishimura W
Year: 2008
Journal: Dev Biol
Title: Preferential reduction of beta cells derived from Pax6-MafB pathway in MafB deficient mice.
Volume: 314
Issue: 2
Pages: 443-56
Publication
First Author: Lynn FC
Year: 2008
Journal: PLoS One
Title: Identification of the bHLH factor Math6 as a novel component of the embryonic pancreas transcriptional network.
Volume: 3
Issue: 6
Pages: e2430
Publication
First Author: Anderson KR
Year: 2009
Journal: J Biol Chem
Title: Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) by Nkx2.2 and neurogenin 3.
Volume: 284
Issue: 45
Pages: 31236-48
Publication
First Author: Harris TE
Year: 2007
Journal: J Biol Chem
Title: Insulin controls subcellular localization and multisite phosphorylation of the phosphatidic acid phosphatase, lipin 1.
Volume: 282
Issue: 1
Pages: 277-86
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Ohlsson H
Year: 1993
Journal: EMBO J
Title: IPF1, a homeodomain-containing transactivator of the insulin gene.
Volume: 12
Issue: 11
Pages: 4251-9
Publication
First Author: Gao N
Year: 2008
Journal: Genes Dev
Title: Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development.
Volume: 22
Issue: 24
Pages: 3435-48
Publication
First Author: Sosa-Pineda B
Year: 1997
Journal: Nature
Title: The Pax4 gene is essential for differentiation of insulin-producing beta cells in the mammalian pancreas.
Volume: 386
Issue: 6623
Pages: 399-402
Publication
First Author: Vuguin PM
Year: 2006
Journal: Endocrinology
Title: Ablation of the glucagon receptor gene increases fetal lethality and produces alterations in islet development and maturation.
Volume: 147
Issue: 9
Pages: 3995-4006
Publication
First Author: Mellitzer G
Year: 2006
Journal: EMBO J
Title: IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas.
Volume: 25
Issue: 6
Pages: 1344-52
Publication
First Author: Gierl MS
Year: 2006
Journal: Genes Dev
Title: The zinc-finger factor Insm1 (IA-1) is essential for the development of pancreatic beta cells and intestinal endocrine cells.
Volume: 20
Issue: 17
Pages: 2465-78
Publication
First Author: Krapp A
Year: 1998
Journal: Genes Dev
Title: The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas.
Volume: 12
Issue: 23
Pages: 3752-63
Publication
First Author: Sander M
Year: 2000
Journal: Development
Title: Homeobox gene Nkx6.1 lies downstream of Nkx2.2 in the major pathway of beta-cell formation in the pancreas.
Volume: 127
Issue: 24
Pages: 5533-40
Publication
First Author: Kim BM
Year: 2007
Journal: Development
Title: Independent functions and mechanisms for homeobox gene Barx1 in patterning mouse stomach and spleen.
Volume: 134
Issue: 20
Pages: 3603-13
Publication
First Author: Arden SD
Year: 1999
Journal: Diabetes
Title: Molecular cloning of a pancreatic islet-specific glucose-6-phosphatase catalytic subunit-related protein.
Volume: 48
Issue: 3
Pages: 531-42
Publication
First Author: Premont RT
Year: 1999
Journal: J Biol Chem
Title: The GRK4 subfamily of G protein-coupled receptor kinases. Alternative splicing, gene organization, and sequence conservation.
Volume: 274
Issue: 41
Pages: 29381-9
Publication
First Author: Chiang MK
Year: 1996
Journal: Development
Title: PTP-NP, a new member of the receptor protein tyrosine phosphatase family, implicated in development of nervous system and pancreatic endocrine cells.
Volume: 122
Issue: 7
Pages: 2239-50
Publication
First Author: Soyer J
Year: 2010
Journal: Development
Title: Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development.
Volume: 137
Issue: 2
Pages: 203-12
Publication
First Author: Smith SB
Year: 2010
Journal: Nature
Title: Rfx6 directs islet formation and insulin production in mice and humans.
Volume: 463
Issue: 7282
Pages: 775-80
Publication
First Author: Kaestner KH
Year: 1999
Journal: Genes Dev
Title: Inactivation of the winged helix transcription factor HNF3alpha affects glucose homeostasis and islet glucagon gene expression in vivo.
Volume: 13
Issue: 4
Pages: 495-504
Publication
First Author: Cromphout K
Year: 2006
Journal: Mol Cell Biol
Title: The normal phenotype of Pmm1-deficient mice suggests that Pmm1 is not essential for normal mouse development.
Volume: 26
Issue: 15
Pages: 5621-35
Publication  
First Author: Li S
Year: 2010
Journal: BMC Dev Biol
Title: SEL1L deficiency impairs growth and differentiation of pancreatic epithelial cells.
Volume: 10
Pages: 19
Publication
First Author: Sohaskey ML
Year: 2010
Journal: J Cell Biol
Title: Osteopotentia regulates osteoblast maturation, bone formation, and skeletal integrity in mice.
Volume: 189
Issue: 3
Pages: 511-25
Publication
First Author: Akpinar P
Year: 2005
Journal: Cell Metab
Title: Tmem27: a cleaved and shed plasma membrane protein that stimulates pancreatic beta cell proliferation.
Volume: 2
Issue: 6
Pages: 385-97
Publication
First Author: De Franco E
Year: 2019
Journal: Am J Hum Genet
Title: A Specific CNOT1 Mutation Results in a Novel Syndrome of Pancreatic Agenesis and Holoprosencephaly through Impaired Pancreatic and Neurological Development.
Volume: 104
Issue: 5
Pages: 985-989
Publication
First Author: Claiborn KC
Year: 2010
Journal: J Clin Invest
Title: Pcif1 modulates Pdx1 protein stability and pancreatic β cell function and survival in mice.
Volume: 120
Issue: 10
Pages: 3713-21
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Meissburger B
Year: 2011
Journal: EMBO Mol Med
Title: Adipogenesis and insulin sensitivity in obesity are regulated by retinoid-related orphan receptor gamma.
Volume: 3
Issue: 11
Pages: 637-51
Publication
First Author: Krebs DL
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Development of hydrocephalus in mice lacking SOCS7.
Volume: 101
Issue: 43
Pages: 15446-51
Publication
First Author: Akiyama T
Year: 2005
Journal: Science
Title: Dependence of self-tolerance on TRAF6-directed development of thymic stroma.
Volume: 308
Issue: 5719
Pages: 248-51
Publication
First Author: Minn AH
Year: 2005
Journal: Mol Endocrinol
Title: Increased insulin translation from an insulin splice-variant overexpressed in diabetes, obesity, and insulin resistance.
Volume: 19
Issue: 3
Pages: 794-803
Publication
First Author: Crossley PH
Year: 1995
Journal: Development
Title: The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo.
Volume: 121
Issue: 2
Pages: 439-51
Publication
First Author: Artner I
Year: 2010
Journal: Diabetes
Title: MafA and MafB regulate genes critical to beta-cells in a unique temporal manner.
Volume: 59
Issue: 10
Pages: 2530-9
Publication
First Author: Kang HS
Year: 2009
Journal: Mol Cell Biol
Title: Transcription factor Glis3, a novel critical player in the regulation of pancreatic beta-cell development and insulin gene expression.
Volume: 29
Issue: 24
Pages: 6366-79
Publication
First Author: Henseleit KD
Year: 2005
Journal: Development
Title: NKX6 transcription factor activity is required for alpha- and beta-cell development in the pancreas.
Volume: 132
Issue: 13
Pages: 3139-49
Publication
First Author: Schaffer AE
Year: 2013
Journal: PLoS Genet
Title: Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity.
Volume: 9
Issue: 1
Pages: e1003274
Publication
First Author: Kepner EM
Year: 2011
Journal: Am J Physiol Endocrinol Metab
Title: Cool-1/βPIX functions as a guanine nucleotide exchange factor in the cycling of Cdc42 to regulate insulin secretion.
Volume: 301
Issue: 6
Pages: E1072-80
Publication
First Author: Akerblom B
Year: 2007
Journal: Mol Cell Endocrinol
Title: A role of FRK in regulation of embryonal pancreatic beta cell formation.
Volume: 270
Issue: 1-2
Pages: 73-8
Publication
First Author: Zhao Y
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Ubl4A is required for insulin-induced Akt plasma membrane translocation through promotion of Arp2/3-dependent actin branching.
Volume: 112
Issue: 31
Pages: 9644-9
Publication
First Author: Jonckheere N
Year: 2008
Journal: Dev Biol
Title: Analysis of mPygo2 mutant mice suggests a requirement for mesenchymal Wnt signaling in pancreatic growth and differentiation.
Volume: 318
Issue: 2
Pages: 224-35
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Gao N
Year: 2010
Journal: Mol Endocrinol
Title: Foxa1 and Foxa2 maintain the metabolic and secretory features of the mature beta-cell.
Volume: 24
Issue: 8
Pages: 1594-604
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication
First Author: Tsuchiya Y
Year: 2018
Journal: J Cell Biol
Title: IRE1-XBP1 pathway regulates oxidative proinsulin folding in pancreatic β cells.
Volume: 217
Issue: 4
Pages: 1287-1301
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication      
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
Publication
First Author: Yang Y
Year: 2011
Journal: Diabetologia
Title: The Krüppel-like zinc finger protein GLIS3 transactivates neurogenin 3 for proper fetal pancreatic islet differentiation in mice.
Volume: 54
Issue: 10
Pages: 2595-605
Publication
First Author: Yang Y
Year: 2017
Journal: Endocrinology
Title: Differential Gene Dosage Effects of Diabetes-Associated Gene GLIS3 in Pancreatic β Cell Differentiation and Function.
Volume: 158
Issue: 1
Pages: 9-20
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Lemaire LA
Year: 2015
Journal: Development
Title: Bicaudal C1 promotes pancreatic NEUROG3+ endocrine progenitor differentiation and ductal morphogenesis.
Volume: 142
Issue: 5
Pages: 858-70