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Search results 201 to 300 out of 1200 for Mdm2

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Type Details Score
Publication
First Author: Lu WY
Year: 2015
Journal: Nat Cell Biol
Title: Hepatic progenitor cells of biliary origin with liver repopulation capacity.
Volume: 17
Issue: 8
Pages: 971-983
Publication
First Author: Pourebrahim R
Year: 2023
Journal: Cell Death Dis
Title: Mdm2/p53 levels in bone marrow mesenchymal stromal cells are essential for maintaining the hematopoietic niche in response to DNA damage.
Volume: 14
Issue: 6
Pages: 371
Publication
First Author: Lengner CJ
Year: 2006
Journal: J Cell Biol
Title: Osteoblast differentiation and skeletal development are regulated by Mdm2-p53 signaling.
Volume: 172
Issue: 6
Pages: 909-21
Publication
First Author: Toledo F
Year: 2006
Journal: Cancer Cell
Title: A mouse p53 mutant lacking the proline-rich domain rescues Mdm4 deficiency and provides insight into the Mdm2-Mdm4-p53 regulatory network.
Volume: 9
Issue: 4
Pages: 273-85
Publication
First Author: Montes de Oca Luna R
Year: 1995
Journal: Nature
Title: Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53.
Volume: 378
Issue: 6553
Pages: 203-6
Publication
First Author: Post SM
Year: 2010
Journal: Cancer Cell
Title: A high-frequency regulatory polymorphism in the p53 pathway accelerates tumor development.
Volume: 18
Issue: 3
Pages: 220-30
Publication  
First Author: Li X
Year: 2016
Journal: Nat Commun
Title: The MDM2-p53-pyruvate carboxylase signalling axis couples mitochondrial metabolism to glucose-stimulated insulin secretion in pancreatic β-cells.
Volume: 7
Pages: 11740
Publication
First Author: Ye B
Year: 2014
Journal: Stem Cells
Title: Pcid2 inactivates developmental genes in human and mouse embryonic stem cells to sustain their pluripotency by modulation of EID1 stability.
Volume: 32
Issue: 3
Pages: 623-35
Publication  
First Author: Nagarajan S
Year: 2017
Journal: Mol Cell Endocrinol
Title: Protein Phosphatase 1α enhances renal aldosterone signaling via mineralocorticoid receptor stabilization.
Volume: 450
Pages: 74-82
Publication
First Author: Lu X
Year: 2007
Journal: Cancer Cell
Title: The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop.
Volume: 12
Issue: 4
Pages: 342-54
Publication
First Author: Weber JD
Year: 2000
Journal: Genes Dev
Title: p53-independent functions of the p19(ARF) tumor suppressor.
Volume: 14
Issue: 18
Pages: 2358-65
Publication
First Author: Tsai NP
Year: 2012
Journal: Cell
Title: Multiple autism-linked genes mediate synapse elimination via proteasomal degradation of a synaptic scaffold PSD-95.
Volume: 151
Issue: 7
Pages: 1581-94
Publication
First Author: Nozaki T
Year: 1997
Journal: Biochem Biophys Res Commun
Title: Abrogation of G1 arrest after DNA damage is associated with constitutive overexpression of Mdm2, Cdk4, and Irf1 mRNAs in the BALB/c 3T3 A31 variant 1-1 clone.
Volume: 233
Issue: 1
Pages: 216-20
Publication
First Author: Hasan MK
Year: 2002
Journal: J Biol Chem
Title: CARF is a novel protein that cooperates with mouse p19ARF (human p14ARF) in activating p53.
Volume: 277
Issue: 40
Pages: 37765-70
Publication
First Author: Mikawa T
Year: 2014
Journal: J Cell Biol
Title: Senescence-inducing stress promotes proteolysis of phosphoglycerate mutase via ubiquitin ligase Mdm2.
Volume: 204
Issue: 5
Pages: 729-45
Publication
First Author: Brady SN
Year: 2004
Journal: Mol Cell Biol
Title: ARF impedes NPM/B23 shuttling in an Mdm2-sensitive tumor suppressor pathway.
Volume: 24
Issue: 21
Pages: 9327-38
Publication
First Author: Zhang Z
Year: 2008
Journal: EMBO J
Title: Proteasome activator PA28 gamma regulates p53 by enhancing its MDM2-mediated degradation.
Volume: 27
Issue: 6
Pages: 852-64
Publication
First Author: Shvarts A
Year: 1996
Journal: EMBO J
Title: MDMX: a novel p53-binding protein with some functional properties of MDM2.
Volume: 15
Issue: 19
Pages: 5349-57
Publication
First Author: Jaako P
Year: 2017
Journal: Leukemia
Title: Induction of the 5S RNP-Mdm2-p53 ribosomal stress pathway delays the initiation but fails to eradicate established murine acute myeloid leukemia.
Volume: 31
Issue: 1
Pages: 213-221
Publication
First Author: Matsui Y
Year: 2016
Journal: J Biol Chem
Title: Core Binding Factor β Protects HIV, Type 1 Accessory Protein Viral Infectivity Factor from MDM2-mediated Degradation.
Volume: 291
Issue: 48
Pages: 24892-24899
Publication
First Author: Busuttil V
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: NF-kappaB inhibits T-cell activation-induced, p73-dependent cell death by induction of MDM2.
Volume: 107
Issue: 42
Pages: 18061-6
Publication
First Author: Pant V
Year: 2013
Journal: Genes Dev
Title: The p53-Mdm2 feedback loop protects against DNA damage by inhibiting p53 activity but is dispensable for p53 stability, development, and longevity.
Volume: 27
Issue: 17
Pages: 1857-67
Publication
First Author: Boesten LS
Year: 2006
Journal: Cell Death Differ
Title: Mdm2, but not Mdm4, protects terminally differentiated smooth muscle cells from p53-mediated caspase-3-independent cell death.
Volume: 13
Issue: 12
Pages: 2089-98
Publication
First Author: Macias E
Year: 2010
Journal: Cancer Cell
Title: An ARF-independent c-MYC-activated tumor suppression pathway mediated by ribosomal protein-Mdm2 Interaction.
Volume: 18
Issue: 3
Pages: 231-43
Publication
First Author: Livera G
Year: 2016
Journal: FEBS Lett
Title: Loss of oocytes due to conditional ablation of Murine double minute 2 (Mdm2) gene is p53-dependent and results in female sterility.
Volume: 590
Issue: 16
Pages: 2566-74
Publication
First Author: Zhang CX
Year: 2017
Journal: Am J Pathol
Title: Mouse Double Minute 2 Actively Suppresses p53 Activity in Oocytes during Mouse Folliculogenesis.
Volume: 187
Issue: 2
Pages: 339-351
Publication
First Author: Gannon HS
Year: 2011
Journal: Dev Biol
Title: Mdm2-p53 signaling regulates epidermal stem cell senescence and premature aging phenotypes in mouse skin.
Volume: 353
Issue: 1
Pages: 1-9
Publication
First Author: Liu DC
Year: 2019
Journal: PLoS Genet
Title: Novel roles of ER stress in repressing neural activity and seizures through Mdm2- and p53-dependent protein translation.
Volume: 15
Issue: 9
Pages: e1008364
Publication
First Author: Liu Z
Year: 2018
Journal: Diabetes
Title: The Dysfunctional MDM2-p53 Axis in Adipocytes Contributes to Aging-Related Metabolic Complications by Induction of Lipodystrophy.
Volume: 67
Issue: 11
Pages: 2397-2409
Publication
First Author: Franklin DA
Year: 2023
Journal: J Biol Chem
Title: Ribosomal protein RPL11 haploinsufficiency causes anemia in mice via activation of the RP-MDM2-p53 pathway.
Volume: 299
Issue: 1
Pages: 102739
Publication
First Author: Valentin-Vega YA
Year: 2008
Journal: Cell Death Differ
Title: The intestinal epithelium compensates for p53-mediated cell death and guarantees organismal survival.
Volume: 15
Issue: 11
Pages: 1772-81
Publication
First Author: Roudier E
Year: 2012
Journal: FASEB J
Title: Murine double minute-2 expression is required for capillary maintenance and exercise-induced angiogenesis in skeletal muscle.
Volume: 26
Issue: 11
Pages: 4530-9
Publication  
First Author: Jaramillo-Rangel G
Year: 2013
Journal: Mol Vis
Title: p53 E3 ubiquitin protein ligase homolog regulates p53 in vivo in the adult mouse eye lens.
Volume: 19
Pages: 2468-76
Publication
First Author: Zhang X
Year: 2015
Journal: Oncogene
Title: Impact of the Mdm2(SNP309-G) allele on a murine model of colorectal cancer.
Volume: 34
Issue: 33
Pages: 4412-20
Publication
First Author: Liu Y
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Ribosomal protein-Mdm2-p53 pathway coordinates nutrient stress with lipid metabolism by regulating MCD and promoting fatty acid oxidation.
Volume: 111
Issue: 23
Pages: E2414-22
Publication
First Author: Jones SN
Year: 1995
Journal: Nature
Title: Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53.
Volume: 378
Issue: 6553
Pages: 206-8
Publication
First Author: Jones SN
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: The tumorigenic potential and cell growth characteristics of p53-deficient cells are equivalent in the presence or absence of Mdm2.
Volume: 93
Issue: 24
Pages: 14106-11
Publication
First Author: Vecino R
Year: 2018
Journal: Sci Rep
Title: The MDM2-p53 pathway is involved in preconditioning-induced neuronal tolerance to ischemia.
Volume: 8
Issue: 1
Pages: 1610
Publication
First Author: Stoyanova T
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: DDB2 decides cell fate following DNA damage.
Volume: 106
Issue: 26
Pages: 10690-5
Publication
First Author: Knippschild U
Year: 1995
Journal: Oncogene
Title: Cell-specific transcriptional activation of the mdm2-gene by ectopically expressed wild-type form of a temperature-sensitive mutant p53.
Volume: 11
Issue: 4
Pages: 683-90
Publication
First Author: Kubbutat MH
Year: 1997
Journal: Nature
Title: Regulation of p53 stability by Mdm2.
Volume: 387
Issue: 6630
Pages: 299-303
Publication
First Author: Tao W
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Nucleocytoplasmic shuttling of oncoprotein Hdm2 is required for Hdm2-mediated degradation of p53.
Volume: 96
Issue: 6
Pages: 3077-80
Publication
First Author: O'Keefe K
Year: 2003
Journal: Mol Cell Biol
Title: Nucleocytoplasmic shuttling of p53 is essential for MDM2-mediated cytoplasmic degradation but not ubiquitination.
Volume: 23
Issue: 18
Pages: 6396-405
Publication
First Author: Sakurai T
Year: 2005
Journal: Exp Cell Res
Title: Low temperature protects mammalian cells from apoptosis initiated by various stimuli in vitro.
Volume: 309
Issue: 2
Pages: 264-72
Publication  
First Author: Maruyama EO
Year: 2016
Journal: Sci Rep
Title: Extraembryonic but not embryonic SUMO-specific protease 2 is required for heart development.
Volume: 6
Pages: 20999
Publication
First Author: Burke RM
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Small proline-rich protein 2B drives stress-dependent p53 degradation and fibroblast proliferation in heart failure.
Volume: 115
Issue: 15
Pages: E3436-E3445
Publication
First Author: Wang Y
Year: 2018
Journal: J Pathol
Title: HMGA2 promotes intestinal tumorigenesis by facilitating MDM2-mediated ubiquitination and degradation of p53.
Volume: 246
Issue: 4
Pages: 508-518
Publication
First Author: Lim ST
Year: 2008
Journal: Mol Cell
Title: Nuclear FAK promotes cell proliferation and survival through FERM-enhanced p53 degradation.
Volume: 29
Issue: 1
Pages: 9-22
Publication
First Author: Yuan X
Year: 2005
Journal: Mol Cell
Title: Genetic inactivation of the transcription factor TIF-IA leads to nucleolar disruption, cell cycle arrest, and p53-mediated apoptosis.
Volume: 19
Issue: 1
Pages: 77-87
Publication
First Author: Joshi Y
Year: 2015
Journal: Brain
Title: The MDM4/MDM2-p53-IGF1 axis controls axonal regeneration, sprouting and functional recovery after CNS injury.
Volume: 138
Issue: Pt 7
Pages: 1843-62
Publication
First Author: Goh AM
Year: 2015
Journal: Oncotarget
Title: Mutant p53 accumulates in cycling and proliferating cells in the normal tissues of p53 R172H mutant mice.
Volume: 6
Issue: 20
Pages: 17968-80
Publication
First Author: Mesaeli N
Year: 2004
Journal: Mol Biol Cell
Title: Impaired p53 expression, function, and nuclear localization in calreticulin-deficient cells.
Volume: 15
Issue: 4
Pages: 1862-70
Publication
First Author: Haraguchi H
Year: 2019
Journal: FASEB J
Title: Mdm2-p53-SF1 pathway in ovarian granulosa cells directs ovulation and fertilization by conditioning oocyte quality.
Volume: 33
Issue: 2
Pages: 2610-2620
Publication
First Author: Pan D
Year: 2012
Journal: Aging Cell
Title: SnoN activates p53 directly to regulate aging and tumorigenesis.
Volume: 11
Issue: 5
Pages: 902-911
Publication
First Author: Mohibi S
Year: 2021
Journal: Mol Cancer Res
Title: Mice Deficient in the RNA-Binding Protein Zfp871 Are Prone to Early Death and Steatohepatitis in Part through the p53-Mdm2 Axis.
Volume: 19
Issue: 10
Pages: 1751-1762
Publication
First Author: Abe Y
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Hedgehog signaling overrides p53-mediated tumor suppression by activating Mdm2.
Volume: 105
Issue: 12
Pages: 4838-43
Publication
First Author: Prives C
Year: 1999
Journal: J Pathol
Title: The p53 pathway.
Volume: 187
Issue: 1
Pages: 112-26
Publication
First Author: You A
Year: 2011
Journal: Arch Biochem Biophys
Title: Transcription factor Nrf2 maintains the basal expression of Mdm2: An implication of the regulation of p53 signaling by Nrf2.
Volume: 507
Issue: 2
Pages: 356-64
Publication
First Author: Thotala DK
Year: 2012
Journal: Cell Death Differ
Title: Glycogen synthase kinase 3β inhibitors protect hippocampal neurons from radiation-induced apoptosis by regulating MDM2-p53 pathway.
Volume: 19
Issue: 3
Pages: 387-96
Publication
First Author: Li H
Year: 2022
Journal: Cell Rep
Title: Destabilization of TP53 by USP10 is essential for neonatal autophagy and survival.
Volume: 41
Issue: 1
Pages: 111435
Publication
First Author: Pan W
Year: 2011
Journal: PLoS One
Title: The in vivo role of the RP-Mdm2-p53 pathway in signaling oncogenic stress induced by pRb inactivation and Ras overexpression.
Volume: 6
Issue: 6
Pages: e21625
Publication
First Author: Huang L
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: The p53 inhibitors MDM2/MDMX complex is required for control of p53 activity in vivo.
Volume: 108
Issue: 29
Pages: 12001-6
Publication
First Author: Xi G
Year: 2019
Journal: J Biol Chem
Title: Hyperglycemia induces vascular smooth muscle cell dedifferentiation by suppressing insulin receptor substrate-1-mediated p53/KLF4 complex stabilization.
Volume: 294
Issue: 7
Pages: 2407-2421
Publication
First Author: Ruland J
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: p53 accumulation, defective cell proliferation, and early embryonic lethality in mice lacking tsg101.
Volume: 98
Issue: 4
Pages: 1859-64
Publication
First Author: Jiang M
Year: 2011
Journal: Cell Death Differ
Title: SUMO-specific protease 2 in Mdm2-mediated regulation of p53.
Volume: 18
Issue: 6
Pages: 1005-15
Publication
First Author: Saito A
Year: 2005
Journal: J Cereb Blood Flow Metab
Title: Modulation of p53 degradation via MDM2-mediated ubiquitylation and the ubiquitin-proteasome system during reperfusion after stroke: role of oxidative stress.
Volume: 25
Issue: 2
Pages: 267-80
Publication
First Author: Zhang G
Year: 2008
Journal: J Biol Chem
Title: Multiple cyclin kinase inhibitors promote bile acid-induced apoptosis and autophagy in primary hepatocytes via p53-CD95-dependent signaling.
Volume: 283
Issue: 36
Pages: 24343-58
Publication
First Author: Jin XL
Year: 2009
Journal: Biol Reprod
Title: Preimplantation embryo development in the mouse requires the latency of TRP53 expression, which is induced by a ligand-activated PI3 kinase/AKT/MDM2-mediated signaling pathway.
Volume: 80
Issue: 2
Pages: 286-94
Publication
First Author: De Clercq S
Year: 2010
Journal: Mol Cell Biol
Title: Widespread overexpression of epitope-tagged Mdm4 does not accelerate tumor formation in vivo.
Volume: 30
Issue: 22
Pages: 5394-405
Publication
First Author: Furlan A
Year: 2012
Journal: J Hepatol
Title: Met acts through Abl to regulate p53 transcriptional outcomes and cell survival in the developing liver.
Volume: 57
Issue: 6
Pages: 1292-8
Publication
First Author: Pant V
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Transient enhancement of p53 activity protects from radiation-induced gastrointestinal toxicity.
Volume: 116
Issue: 35
Pages: 17429-17437
Publication
First Author: Chavez-Reyes A
Year: 2003
Journal: Cancer Res
Title: Switching mechanisms of cell death in mdm2- and mdm4-null mice by deletion of p53 downstream targets.
Volume: 63
Issue: 24
Pages: 8664-9
Publication
First Author: Bianchetta MJ
Year: 2011
Journal: J Neurosci
Title: Cyclin-dependent kinase 5 regulates PSD-95 ubiquitination in neurons.
Volume: 31
Issue: 33
Pages: 12029-35
Publication  
First Author: Zheng H
Year: 2023
Journal: Development
Title: CHIP inhibits odontoblast differentiation through promoting DLX3 polyubiquitylation and degradation.
Volume: 150
Issue: 10
Publication
First Author: Leri A
Year: 1999
Journal: Circ Res
Title: Overexpression of insulin-like growth factor-1 attenuates the myocyte renin-angiotensin system in transgenic mice.
Volume: 84
Issue: 7
Pages: 752-62
Publication
First Author: Mekhail K
Year: 2005
Journal: J Cell Biol
Title: Regulation of ubiquitin ligase dynamics by the nucleolus.
Volume: 170
Issue: 5
Pages: 733-44
Publication
First Author: Giglio S
Year: 2010
Journal: Oncogene
Title: Regulation of MDM4 (MDMX) function by p76(MDM2): a new facet in the control of p53 activity.
Volume: 29
Issue: 44
Pages: 5935-45
Publication
First Author: Makino Y
Year: 2022
Journal: Cancer Res
Title: Constitutive Activation of the Tumor Suppressor p53 in Hepatocytes Paradoxically Promotes Non-Cell Autonomous Liver Carcinogenesis.
Volume: 82
Issue: 16
Pages: 2860-2873
Publication
First Author: Fouchécourt S
Year: 2016
Journal: Cell Death Differ
Title: Apoptosis of Sertoli cells after conditional ablation of murine double minute 2 (Mdm2) gene is p53-dependent and results in male sterility.
Volume: 23
Issue: 3
Pages: 521-30
Publication  
First Author: Laos M
Year: 2017
Journal: Sci Rep
Title: Indispensable role of Mdm2/p53 interaction during the embryonic and postnatal inner ear development.
Volume: 7
Pages: 42216
Publication
First Author: Anamthathmakula P
Year: 2019
Journal: Sci Rep
Title: Steroidogenic Factor 1 (Nr5a1) is Required for Sertoli Cell Survival Post Sex Determination.
Volume: 9
Issue: 1
Pages: 4452
Gene
Type: gene
Organism: frog, African clawed
Publication
First Author: Zhang G
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: p53 pathway is involved in cell competition during mouse embryogenesis.
Volume: 114
Issue: 3
Pages: 498-503
Publication
First Author: Aboudehen K
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Mechanisms of p53 activation and physiological relevance in the developing kidney.
Volume: 302
Issue: 8
Pages: F928-40
Publication
First Author: Liu G
Year: 2007
Journal: J Pathol
Title: The p53-Mdm2 network in progenitor cell expansion during mouse postnatal development.
Volume: 213
Issue: 4
Pages: 360-8
Publication
First Author: Golestaneh N
Year: 2006
Journal: Brain Res
Title: Cell cycle deregulation and loss of stem cell phenotype in the subventricular zone of TGF-beta adaptor elf-/- mouse brain.
Volume: 1108
Issue: 1
Pages: 45-53
Publication
First Author: Hara MR
Year: 2011
Journal: Nature
Title: A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1.
Volume: 477
Issue: 7364
Pages: 349-53
Publication  
First Author: Beauchamp MC
Year: 2022
Journal: Int J Mol Sci
Title: Craniofacial Defects in Embryos with Homozygous Deletion of Eftud2 in Their Neural Crest Cells Are Not Rescued by Trp53 Deletion.
Volume: 23
Issue: 16
Publication
First Author: Yao F
Year: 2023
Journal: Cell Death Dis
Title: Deletion of ARGLU1 causes global defects in alternative splicing in vivo and mouse cortical malformations primarily via apoptosis.
Volume: 14
Issue: 8
Pages: 543
Publication  
First Author: Li Q
Year: 2019
Journal: JCI Insight
Title: Disruption of Robo2-Baiap2 integrated signaling drives cystic disease.
Volume: 4
Issue: 18
Publication
First Author: Vuong L
Year: 2012
Journal: Invest Ophthalmol Vis Sci
Title: Pattern of expression of p53, its family members, and regulators during early ocular development and in the post-mitotic retina.
Volume: 53
Issue: 8
Pages: 4821-31
Publication  
First Author: Hilliard SA
Year: 2020
Journal: Mech Dev
Title: Mdm4 controls ureteric bud branching via regulation of p53 activity.
Volume: 163
Pages: 103616
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory