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Search results 1 to 33 out of 33 for Src

Category restricted to InteractionExperiment (x)

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Category: InteractionExperiment
Type Details Score
Interaction Experiment
Description: Dishevelled-2 docks and activates Src in a Wnt-dependent manner.
Interaction Experiment
Description: Src kinase activity is essential for osteoclast function.
Interaction Experiment
Description: Angiopoietin-1 prevents VEGF-induced endothelial permeability by sequestering Src through mDia.
Interaction Experiment
Description: Grb2 forms an inducible protein complex with CD28 through a Src homology 3 domain-proline interaction.
Interaction Experiment
Description: Molecular conformation dictates signaling module formation: example of PKCepsilon and Src tyrosine kinase.
Interaction Experiment
Description: Physical association between Src homology 3 elements and the protein product of the c-cbl proto-oncogene.
Interaction Experiment
Description: Autophagic targeting of Src promotes cancer cell survival following reduced FAK signalling.
Interaction Experiment
Description: PKA phosphorylation of Src mediates cAMPs inhibition of cell growth via Rap1.
Interaction Experiment
Description: Dynamin forms a Src kinase-sensitive complex with Cbl and regulates podosomes and osteoclast activity.
Interaction Experiment
Description: beta -Arrestin-mediated recruitment of the Src family kinase Yes mediates endothelin-1-stimulated glucose transport.
Interaction Experiment
Description: A novel nuclear Src and p300 signaling axis controls migratory and invasive behavior in pancreatic cancer.
Interaction Experiment
Description: Contribution of Src and Ras pathways in FGF-2 induced endothelial cell differentiation.
Interaction Experiment
Description: A novel mechanism of modulation of hyperpolarization-activated cyclic nucleotide-gated channels by Src kinase.
Interaction Experiment
Description: Intersectin, a novel adaptor protein with two Eps15 homology and five Src homology 3 domains.
Interaction Experiment
Description: Complexes of focal adhesion kinase (FAK) and Crk-associated substrate (p130(Cas)) are elevated in cytoskeleton-associated fractions following adhesion and Src transformation. Requirements for Src kinase activity and FAK proline-rich motifs.
Interaction Experiment
Description: Dot far-western blot analysis of relative binding affinities of the Src homology 3 domains of Efs and its related proteins.
Interaction Experiment
Description: Single point mutation in Bin/Amphiphysin/Rvs (BAR) sequence of endophilin impairs dimerization, membrane shaping, and Src homology 3 domain-mediated partnership.
Interaction Experiment
Description: A juxtamembrane tyrosine in the colony stimulating factor-1 receptor regulates ligand-induced Src association, receptor kinase function, and down-regulation.
Interaction Experiment
Description: The Tom1L1-clathrin heavy chain complex regulates membrane partitioning of the tyrosine kinase Src required for mitogenic and transforming activities.
Interaction Experiment
Description: Nck-2, a novel Src homology2/3-containing adaptor protein that interacts with the LIM-only protein PINCH and components of growth factor receptor kinase-signaling pathways.
Interaction Experiment
Description: The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules.
Interaction Experiment
Description: A role for CAP, a novel, multifunctional Src homology 3 domain-containing protein in formation of actin stress fibers and focal adhesions.
Interaction Experiment
Description: A hrs binding protein having a Src homology 3 domain is involved in intracellular degradation of growth factors and their receptors.
Interaction Experiment
Description: Src homology 2 (SH2)-containing 5-inositol phosphatase localizes to podosomes, and the SH2 domain is implicated in the attenuation of bone resorption in osteoclasts.
Interaction Experiment
Description: Src and Pyk2 mediate G-protein-coupled receptor activation of epidermal growth factor receptor (EGFR) but are not required for coupling to the mitogen-activated protein (MAP) kinase signaling cascade.
Interaction Experiment
Description: A caveolin-3 mutant that causes limb girdle muscular dystrophy type 1C disrupts Src localization and activity and induces apoptosis in skeletal myotubes.
Interaction Experiment
Description: Regulation of CDC42 GTPase by proline-rich tyrosine kinase 2 interacting with PSGAP, a novel pleckstrin homology and Src homology 3 domain containing rhoGAP protein.
Interaction Experiment
Description: mSiglec-E, a novel mouse CD33-related siglec (sialic acid-binding immunoglobulin-like lectin) that recruits Src homology 2 (SH2)-domain-containing protein tyrosine phosphatases SHP-1 and SHP-2.
Interaction Experiment
Description: Rhodocytin induces platelet aggregation by interacting with glycoprotein Ia/IIa (GPIa/IIa, Integrin alpha 2beta 1). Involvement of GPIa/IIa-associated src and protein tyrosine phosphorylation.
Interaction Experiment
Description: A mammalian adaptor protein with conserved Src homology 2 and phosphotyrosine-binding domains is related to Shc and is specifically expressed in the brain.
Interaction Experiment
Description: Using a phage display library to identify basic residues in A-Raf required to mediate binding to the Src homology 2 domains of the p85 subunit of phosphatidylinositol 3-kinase.
Interaction Experiment
Description: Angiotensin II-induced neural differentiation via angiotensin II type 2 (AT2) receptor-MMS2 cascade involving interaction between AT2 receptor-interacting protein and Src homology 2 domain-containing protein-tyrosine phosphatase 1.
Interaction Experiment
Description: Identification of a link between the SAMP repeats of adenomatous polyposis coli tumor suppressor and the Src homology 3 domain of DDEF.