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Search results 301 to 353 out of 353 for Apobec3

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Type Details Score
GXD Expression
GXD Expression
     
Probe: MGI:5829704
Assay Type: RNA in situ
Annotation Date: 2017-03-28
Strength: Absent
Sex: Male
Emaps: EMAPS:3226225
Stage: TS25
Assay Id: MGI:5829752
Age: embryonic day 17.5
Specimen Label: Supplemental Table E17.5 male
Detected: false
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:5829704
Assay Type: RNA in situ
Annotation Date: 2017-03-28
Strength: Absent
Sex: Male
Emaps: EMAPS:3226228
Stage: TS28
Assay Id: MGI:5829752
Age: postnatal day 5
Specimen Label: Supplemental Table P5 male
Detected: false
Specimen Num: 11
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GXD Expression
GXD Expression
   
Probe: MGI:3724949
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1768022
Stage: TS22
Assay Id: MGI:5421600
Age: embryonic day 14.5
Note: Expression was not detected in the skull (base and vault).
Specimen Label: MH1599; Specimen C1124
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5829704
Assay Type: RNA in situ
Annotation Date: 2017-03-28
Strength: Absent
Sex: Male
Emaps: EMAPS:3612625
Stage: TS25
Assay Id: MGI:5829752
Age: embryonic day 17.5
Specimen Label: Supplemental Table E17.5 male
Detected: false
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:5829704
Assay Type: RNA in situ
Annotation Date: 2017-03-28
Strength: Absent
Sex: Male
Emaps: EMAPS:3612628
Stage: TS28
Assay Id: MGI:5829752
Age: postnatal day 5
Specimen Label: Supplemental Table P5 male
Detected: false
Specimen Num: 11
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GXD Expression
GXD Expression
   
Probe: MGI:3724949
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2672022
Stage: TS22
Assay Id: MGI:5421600
Age: embryonic day 14.5
Note: Expression was not detected in whisker follicle.
Specimen Label: MH1599; Specimen C1124
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5829704
Assay Type: RNA in situ
Annotation Date: 2017-03-28
Strength: Present
Sex: Female
Emaps: EMAPS:3815322
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5829752
Age: embryonic day 14.5
Image: 4V
Note: There were no noteworthy sex differences in staining within the lower urinary tract.
Specimen Label: 4V
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:5829704
Assay Type: RNA in situ
Annotation Date: 2017-03-28
Strength: Present
Sex: Female
Emaps: EMAPS:3816125
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:5829752
Age: embryonic day 17.5
Image: 4W
Note: There were no noteworthy sex differences in staining within the lower urinary tract.
Specimen Label: 4W
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:5829704
Assay Type: RNA in situ
Annotation Date: 2017-03-28
Strength: Ambiguous
Sex: Female
Emaps: EMAPS:3816128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5829752
Age: postnatal day 5
Image: 4X
Note: There were no noteworthy sex differences in staining within the lower urinary tract.
Specimen Label: 4X
Specimen Num: 6
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:15839
       
First Author: International Committee on Standardized Genetic Nomenclature for Mice
Year: 1993
Title: Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
- | J:68300
   
First Author: Strausberg R
Year: 2001
Journal: GenBank Submission
Title: Mus musculus, clone MGC: 7002, mRNA, complete cds
Pages: BC003314
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Protein
B5T0J0
Organism: Mus musculus/domesticus
Length: 373  
Fragment?: false
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Protein
B5T0I8
Organism: Mus musculus/domesticus
Length: 373  
Fragment?: false
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Publication
33947663 | J:310822
First Author: Venkatesan S
Year: 2021
Journal: Cancer Discov
Title: Induction of APOBEC3 Exacerbates DNA Replication Stress and Chromosomal Instability in Early Breast and Lung Cancer Evolution.
Volume: 11
Issue: 10
Pages: 2456-2473
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Publication
19153233 | J:244402
First Author: Okeoma CM
Year: 2009
Journal: J Virol
Title: Expression of murine APOBEC3 alleles in different mouse strains and their effect on mouse mammary tumor virus infection.
Volume: 83
Issue: 7
Pages: 3029-38
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Publication
25408426 | -
First Author: Kim DY
Year: 2015
Journal: Arch Pharm Res
Title: The assembly of Vif ubiquitin E3 ligase for APOBEC3 degradation.
Volume: 38
Issue: 4
Pages: 435-45
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Allele
Apobec3<em2Smoc> | MGI:7288300
Name: apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6474782 | C57BL/6-Apobec3<em2Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Apobec3<em1Smoc> | MGI:7288299
Name: apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Publication
18304004 | -
 
First Author: Chiu YL
Year: 2008
Journal: Annu Rev Immunol
Title: The APOBEC3 cytidine deaminases: an innate defensive network opposing exogenous retroviruses and endogenous retroelements.
Volume: 26
Pages: 317-53
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Publication
22915799 | -
First Author: Phalora PK
Year: 2012
Journal: J Virol
Title: HIV-1 replication and APOBEC3 antiviral activity are not regulated by P bodies.
Volume: 86
Issue: 21
Pages: 11712-24
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Publication
26091828 | J:227235
First Author: Swanton C
Year: 2015
Journal: Cancer Discov
Title: APOBEC Enzymes: Mutagenic Fuel for Cancer Evolution and Heterogeneity.
Volume: 5
Issue: 7
Pages: 704-12
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Publication
32870257 | J:298716
 
First Author: Law EK
Year: 2020
Journal: J Exp Med
Title: APOBEC3A catalyzes mutation and drives carcinogenesis in vivo.
Volume: 217
Issue: 12
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Publication
1995946 | -
First Author: Guy B
Year: 1991
Journal: J Virol
Title: A specific inhibitor of cysteine proteases impairs a Vif-dependent modification of human immunodeficiency virus type 1 Env protein.
Volume: 65
Issue: 3
Pages: 1325-31
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Publication
1357189 | -
First Author: Gabuzda DH
Year: 1992
Journal: J Virol
Title: Role of vif in replication of human immunodeficiency virus type 1 in CD4+ T lymphocytes.
Volume: 66
Issue: 11
Pages: 6489-95
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Publication
3497453 | -
First Author: Fisher AG
Year: 1987
Journal: Science
Title: The sor gene of HIV-1 is required for efficient virus transmission in vitro.
Volume: 237
Issue: 4817
Pages: 888-93
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Publication
14618252 | -
First Author: Pomerantz RJ
Year: 2003
Journal: Cell Mol Life Sci
Title: The HIV-1 Vif protein: a paradigm for viral:cell interactions.
Volume: 60
Issue: 10
Pages: 2017-9
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Publication
24586532 | -
First Author: da Costa KS
Year: 2014
Journal: PLoS One
Title: Structural analysis of viral infectivity factor of HIV type 1 and its interaction with A3G, EloC and EloB.
Volume: 9
Issue: 2
Pages: e89116
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Publication
30961890 | -
First Author: Ball KA
Year: 2019
Journal: Biophys J
Title: Conformational Dynamics of the HIV-Vif Protein Complex.
Volume: 116
Issue: 8
Pages: 1432-1445
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Publication
30941116 | -
 
First Author: Zhao Z
Year: 2019
Journal: Front Microbiol
Title: CAEV Vif Hijacks ElonginB/C, CYPA and Cullin5 to Assemble the E3 Ubiquitin Ligase Complex Stepwise to Degrade oaA3Z2-Z3.
Volume: 10
Pages: 565
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Protein Domain
IPR000475 | Vif
Type: Family
Description: The virion infectivity factor (vif) is an accessory protein, which is essential for HIV replication in host cells. Vif of Human immunodeficiency virus 1 (HIV-1) affects the infectivity of virus particles []to T lymphocytes and macrophages (in some casesincreasing the infectivity of HIV-1 particles by 100- to 1000-fold), but has no direct effect on transcription, translation or virus release. Vif antibodies are found in the sera of patients at all levels of HIV-1 infection, indicating that vif is expressed in natural infections in vivo. Other lentiviruses, including Simian immunodeficiency virus (SIV-cpz), Visna/Maedi virus, and Feline immunodeficiency virus (FIV), have vif open reading frames, suggestingvif plays an essential role during natural infections [].The expression of vif in BHK-21 cells has been shown to be linked to amodification of the C terminus of gp41env, which modification is inhibited by trans-epoxysuccinyl-L-leucylamido-(4-guanidio)butane (E64), a specific inhibitor of cysteine proteases []. Coupled with sequence analysis and the effects of point mutations in vif, it has been suggested that vif could be a cysteine protease. Virions produced in the absence of Vif have abnormal core morphology and those produced in primary T cells carry immature core proteins and low levels of mature capsid [].In humans, HIV-1 Vif hijacks cellular E3 ligase components containing CUL5, RBX2, ELOB, ELOC and CBFbeta, to poly-ubiquitinate antiviral cellular factors, APOBEC3 proteins [, , ]. In sheep and goats, Caprine arthritis encephalitis virus (CAEV) Vif is responsible for degradation of oaA3Z2-Z3 [].
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Publication
19188259 | J:173040
First Author: MacDuff DA
Year: 2009
Journal: Nucleic Acids Res
Title: AID can restrict L1 retrotransposition suggesting a dual role in innate and adaptive immunity.
Volume: 37
Issue: 6
Pages: 1854-67
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Publication
21398638 | J:173831
First Author: Ikeda T
Year: 2011
Journal: Nucleic Acids Res
Title: Intrinsic restriction activity by apolipoprotein B mRNA editing enzyme APOBEC1 against the mobility of autonomous retrotransposons.
Volume: 39
Issue: 13
Pages: 5538-54
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Publication
21084477 | J:193385
First Author: Sakuma T
Year: 2011
Journal: J Virol
Title: Early events in retrovirus XMRV infection of the wild-derived mouse Mus pahari.
Volume: 85
Issue: 3
Pages: 1205-13
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Publication
27758855 | J:237629
First Author: Matsui Y
Year: 2016
Journal: J Biol Chem
Title: Core Binding Factor β Protects HIV, Type 1 Accessory Protein Viral Infectivity Factor from MDM2-mediated Degradation.
Volume: 291
Issue: 48
Pages: 24892-24899
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Publication
31726973 | J:281668
First Author: Caval V
Year: 2019
Journal: BMC Genomics
Title: Mouse APOBEC1 cytidine deaminase can induce somatic mutations in chromosomal DNA.
Volume: 20
Issue: 1
Pages: 858
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Publication
33351847 | J:299494
First Author: Wei Y
Year: 2020
Journal: PLoS One
Title: Coronavirus genomes carry the signatures of their habitats.
Volume: 15
Issue: 12
Pages: e0244025
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Publication
31409681 | J:292356
 
First Author: Singh GB
Year: 2019
Journal: mBio
Title: A Protein Antagonist of Activation-Induced Cytidine Deaminase Encoded by a Complex Mouse Retrovirus.
Volume: 10
Issue: 4
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Publication
28794032 | J:256423
 
First Author: Bamunusinghe D
Year: 2017
Journal: J Virol
Title: Recombinant Origins of Pathogenic and Nonpathogenic Mouse Gammaretroviruses with Polytropic Host Range.
Volume: 91
Issue: 21
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