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Search results 201 to 233 out of 233 for Tssk6

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0.022s
Type Details Score
Allele  
Name: TSSK6 activating co-chaperone; gene trap IST10845E12, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: TSSK6 activating co-chaperone; gene trap IST13739A2, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: TSSK6 activating co-chaperone; gene trap IST13907B9, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: TSSK6 activating co-chaperone; gene trap IST13954E2, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: TSSK6 activating co-chaperone; gene trap IST14995B10, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: TSSK6 activating co-chaperone; gene trap IST14603F10, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: TSSK6 activating co-chaperone; gene trap IST10931A10, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: TSSK6 activating co-chaperone; gene trap IST14015C6, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: TSSK6 activating co-chaperone; gene trap IST14306C5, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: TSSK6 activating co-chaperone; gene trap IST13847F5, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: TSSK6 activating co-chaperone; gene trap IST14423G8, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: TSSK6 activating co-chaperone; gene trap IST14992E4, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Protein Domain
Type: Domain
Description: STKs (serine/threonine-protein kinases) catalyse the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. TSSK (testis-specific serine kinase) proteins are almost exclusively expressed postmeiotically in the testis and play important roles in spermatogenesis and/or spermiogenesis. There are five mammalian TSSK proteins which show differences in their localization and timing of expression []. TSSK6, also called SSTK, is expressed at the head of elongated sperm. It can phosphorylate histones and associate with heat shock protens HSP90 and HSC70. Male mice deficient in TSSK6 are infertile, showing spermatogenic impairment including reduced sperm counts, impaired DNA condensation, abnormal morphology and decreased motility rates [, ].
Publication      
First Author: Kavarthapu R
Year: 2019
Journal: Hum Mol Genet
Title: Targeted Knock-In Mice with a Human Mutation in GRTH/DDX25 Reveals the Essential Role of Phosphorylated GRTH in Spermatid Development during Spermatogenesis.
Publication
First Author: Nayyab S
Year: 2021
Journal: Mol Reprod Dev
Title: TSSK3, a novel target for male contraception, is required for spermiogenesis.
Volume: 88
Issue: 11
Pages: 718-730
Publication
First Author: Salicioni AM
Year: 2020
Journal: Biol Reprod
Title: Testis-specific serine kinase protein family in male fertility and as targets for non-hormonal male contraception†.
Volume: 103
Issue: 2
Pages: 264-274
Publication  
First Author: Anbazhagan R
Year: 2020
Journal: Front Cell Dev Biol
Title: Role of Phosphorylated Gonadotropin-Regulated Testicular RNA Helicase (GRTH/DDX25) in the Regulation of Germ Cell Specific mRNAs in Chromatoid Bodies During Spermatogenesis.
Volume: 8
Pages: 580019
Protein
Organism: Mus musculus/domesticus
Length: 273  
Fragment?: false
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes