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Search results 1 to 100 out of 645 for Adora2a

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
135 | ADORA2A
Type: gene
Organism: human
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Gene
617828 | ADORA2A
Type: gene
Organism: cattle
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Gene
427705 | ADORA2A
Type: gene
Organism: chicken
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Gene
707865 | ADORA2A
Type: gene
Organism: macaque, rhesus
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Gene
100127551 | adora2a
Type: gene
Organism: frog, western clawed
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Gene
25369 | Adora2a
Type: gene
Organism: rat
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Gene
403960 | ADORA2A
Type: gene
Organism: dog, domestic
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Gene
458714 | ADORA2A
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:99402 | Adora2a
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
646023 | ADORA2A-AS1
Type: gene
Organism: human
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Publication
30886019 | J:276233
First Author: Yamamoto M
Year: 2019
Journal: J Neurosci
Title: Endothelial Adora2a Activation Promotes Blood-Brain Barrier Breakdown and Cognitive Impairment in Mice with Diet-Induced Insulin Resistance.
Volume: 39
Issue: 21
Pages: 4179-4192
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GXD Expression
GXD Expression
     
Probe: MGI:6167035
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6189741
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Adora2a
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6167035
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6189741
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Adora2a
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6167035
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6189741
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Adora2a
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6167035
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6189741
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Adora2a
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6167035
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189741
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Adora2a
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6167035
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189741
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Adora2a
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6167035
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189741
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Adora2a
Detected: true
Specimen Num: 7
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Publication
23349051 | J:211759
First Author: Aggarwal NR
Year: 2013
Journal: Am J Respir Cell Mol Biol
Title: Macrophage A2A adenosinergic receptor modulates oxygen-induced augmentation of murine lung injury.
Volume: 48
Issue: 5
Pages: 635-46
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Publication
24145516 | J:207727
First Author: Cekic C
Year: 2013
Journal: J Exp Med
Title: Extracellular adenosine regulates naive T cell development and peripheral maintenance.
Volume: 210
Issue: 12
Pages: 2693-706
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Publication
28928465 | J:253475
First Author: Liu Z
Year: 2017
Journal: Nat Commun
Title: Endothelial adenosine A2a receptor-mediated glycolysis is essential for pathological retinal angiogenesis.
Volume: 8
Issue: 1
Pages: 584
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Publication
28963505 | J:252747
First Author: Oishi Y
Year: 2017
Journal: Nat Commun
Title: Slow-wave sleep is controlled by a subset of nucleus accumbens core neurons in mice.
Volume: 8
Issue: 1
Pages: 734
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Publication
16177079 | J:118981
First Author: Raskovalova T
Year: 2005
Journal: J Immunol
Title: Gs protein-coupled adenosine receptor signaling and lytic function of activated NK cells.
Volume: 175
Issue: 7
Pages: 4383-91
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Protein Coding Gene
MGP_CAROLIEiJ_G0015438 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0017353 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0017330 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0017291 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0017290 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0017114 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_99402 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0017748 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0016684 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0017086 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0017191 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0017184 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0017264 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0017212 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0017787 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0016468 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0016748 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0030854 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0016251 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
9262401 | J:42276
First Author: Ledent C
Year: 1997
Journal: Nature
Title: Aggressiveness, hypoalgesia and high blood pressure in mice lacking the adenosine A2a receptor.
Volume: 388
Issue: 6643
Pages: 674-8
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Publication
27986907 | J:247878
First Author: Schmiel SE
Year: 2017
Journal: J Immunol
Title: Cutting Edge: Adenosine A2a Receptor Signals Inhibit Germinal Center T Follicular Helper Cell Differentiation during the Primary Response to Vaccination.
Volume: 198
Issue: 2
Pages: 623-628
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Publication
29771938 | J:263535
First Author: Liang D
Year: 2018
Journal: PLoS One
Title: Ability of γδ T cells to modulate the Foxp3 T cell response is dependent on adenosine.
Volume: 13
Issue: 5
Pages: e0197189
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Publication
29928041 | J:263744
First Author: Liang D
Year: 2018
Journal: PLoS One
Title: High level expression of A2ARs is required for the enhancing function, but not for the inhibiting function, of γδ T cells in the autoimmune responses of EAU.
Volume: 13
Issue: 6
Pages: e0199601
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Publication
20798237 | J:167256
First Author: Wallace KL
Year: 2010
Journal: Blood
Title: Adenosine A2A receptors induced on iNKT and NK cells reduce pulmonary inflammation and injury in mice with sickle cell disease.
Volume: 116
Issue: 23
Pages: 5010-20
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Publication
25341542 | J:218281
First Author: Cekic C
Year: 2014
Journal: Cancer Res
Title: Adenosine A2A receptors intrinsically regulate CD8+ T cells in the tumor microenvironment.
Volume: 74
Issue: 24
Pages: 7239-49
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Publication
32061899 | J:317666
 
First Author: Li Y
Year: 2020
Journal: Neuropharmacology
Title: Striatopallidal adenosine A2A receptors in the nucleus accumbens confer motivational control of goal-directed behavior.
Volume: 168
Pages: 108010
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Publication
26216520 | J:264955
First Author: Li Y
Year: 2016
Journal: Neuropsychopharmacology
Title: Optogenetic Activation of Adenosine A2A Receptor Signaling in the Dorsomedial Striatopallidal Neurons Suppresses Goal-Directed Behavior.
Volume: 41
Issue: 4
Pages: 1003-13
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Publication
25892655 | J:223334
 
First Author: Li W
Year: 2015
Journal: Neurobiol Dis
Title: Inactivation of adenosine A2A receptors reverses working memory deficits at early stages of Huntington's disease models.
Volume: 79
Pages: 70-80
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Publication
27520357 | J:235601
First Author: Truong LD
Year: 2016
Journal: Am J Pathol
Title: Macrophage A2A Adenosine Receptors Are Essential to Protect from Progressive Kidney Injury.
Volume: 186
Issue: 10
Pages: 2601-13
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Publication
27312972 | J:239884
 
First Author: Viana da Silva S
Year: 2016
Journal: Nat Commun
Title: Early synaptic deficits in the APP/PS1 mouse model of Alzheimer's disease involve neuronal adenosine A2A receptors.
Volume: 7
Pages: 11915
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Publication
18354001 | J:133212
First Author: Shen HY
Year: 2008
Journal: J Neurosci
Title: A critical role of the adenosine A2A receptor in extrastriatal neurons in modulating psychomotor activity as revealed by opposite phenotypes of striatum and forebrain A2A receptor knock-outs.
Volume: 28
Issue: 12
Pages: 2970-5
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Publication
25869810 | J:283484
First Author: Matos M
Year: 2015
Journal: Biol Psychiatry
Title: Deletion of adenosine A2A receptors from astrocytes disrupts glutamate homeostasis leading to psychomotor and cognitive impairment: relevance to schizophrenia.
Volume: 78
Issue: 11
Pages: 763-74
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Publication
30627646 | J:295111
 
First Author: Canas PM
Year: 2018
Journal: eNeuro
Title: Neuronal Adenosine A2A Receptors Are Critical Mediators of Neurodegeneration Triggered by Convulsions.
Volume: 5
Issue: 6
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Publication
32770138 | J:299278
First Author: Aguiar AS Jr
Year: 2020
Journal: Sci Rep
Title: Neuronal adenosine A2A receptors signal ergogenic effects of caffeine.
Volume: 10
Issue: 1
Pages: 13414
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Publication
17192438 | J:117049
First Author: Xiao D
Year: 2006
Journal: J Neurosci
Title: Forebrain adenosine A2A receptors contribute to L-3,4-dihydroxyphenylalanine-induced dyskinesia in hemiparkinsonian mice.
Volume: 26
Issue: 52
Pages: 13548-55
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Publication
18300283 | J:150990
First Author: Yu L
Year: 2008
Journal: Ann Neurol
Title: Adenosine A2A receptor antagonists exert motor and neuroprotective effects by distinct cellular mechanisms.
Volume: 63
Issue: 3
Pages: 338-46
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Publication
23820821 | J:199140
First Author: Wei CJ
Year: 2014
Journal: Biol Psychiatry
Title: Regulation of fear responses by striatal and extrastriatal adenosine A2A receptors in forebrain.
Volume: 75
Issue: 11
Pages: 855-63
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Publication
22298379 | J:204802
First Author: Matos M
Year: 2012
Journal: Glia
Title: Adenosine A2A receptors modulate glutamate uptake in cultured astrocytes and gliosomes.
Volume: 60
Issue: 5
Pages: 702-16
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Publication
15602504 | J:104338
First Author: Bastia E
Year: 2005
Journal: Neuropsychopharmacology
Title: A crucial role for forebrain adenosine A(2A) receptors in amphetamine sensitization.
Volume: 30
Issue: 5
Pages: 891-900
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Publication
17079665 | J:114707
First Author: Huang QY
Year: 2006
Journal: J Neurosci
Title: Adenosine A2A receptors in bone marrow-derived cells but not in forebrain neurons are important contributors to 3-nitropropionic acid-induced striatal damage as revealed by cell-type-selective inactivation.
Volume: 26
Issue: 44
Pages: 11371-8
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Publication
21734299 | J:274174
First Author: Lazarus M
Year: 2011
Journal: J Neurosci
Title: Arousal effect of caffeine depends on adenosine A2A receptors in the shell of the nucleus accumbens.
Volume: 31
Issue: 27
Pages: 10067-75
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Publication
23276608 | J:197065
 
First Author: Singer P
Year: 2013
Journal: Behav Brain Res
Title: Deletion of striatal adenosine A(2A) receptor spares latent inhibition and prepulse inhibition but impairs active avoidance learning.
Volume: 242
Pages: 54-61
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Publication
19955361 | J:158458
First Author: Yu C
Year: 2009
Journal: J Neurosci
Title: Genetic deletion of A2A adenosine receptors in the striatum selectively impairs habit formation.
Volume: 29
Issue: 48
Pages: 15100-3
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Publication
22529293 | J:188748
First Author: Mills JH
Year: 2012
Journal: J Immunol
Title: A2A adenosine receptor signaling in lymphocytes and the central nervous system regulates inflammation during experimental autoimmune encephalomyelitis.
Volume: 188
Issue: 11
Pages: 5713-22
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Publication
21062644 | J:168621
First Author: Mievis S
Year: 2011
Journal: Neurobiol Dis
Title: A2A receptor knockout worsens survival and motor behaviour in a transgenic mouse model of Huntington's disease.
Volume: 41
Issue: 2
Pages: 570-6
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Publication
37914685 | J:342216
First Author: Todd KL
Year: 2023
Journal: Nat Commun
Title: A(2A)R eGFP reporter mouse enables elucidation of A(2A)R expression dynamics during anti-tumor immune responses.
Volume: 14
Issue: 1
Pages: 6990
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Publication
19936569 | J:252055
 
First Author: Quiroz C
Year: 2009
Journal: ScientificWorldJournal
Title: Key modulatory role of presynaptic adenosine A2A receptors in cortical neurotransmission to the striatal direct pathway.
Volume: 9
Pages: 1321-44
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Publication
16777350 | J:113157
First Author: Li Y
Year: 2006
Journal: Neuroscience
Title: Mouse spinal cord compression injury is reduced by either activation of the adenosine A2A receptor on bone marrow-derived cells or deletion of the A2A receptor on non-bone marrow-derived cells.
Volume: 141
Issue: 4
Pages: 2029-39
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Publication
29501623 | J:262607
 
First Author: Chen PZ
Year: 2018
Journal: Behav Brain Res
Title: Adenosine A2A receptor involves in neuroinflammation-mediated cognitive decline through activating microglia under acute hypobaric hypoxia.
Volume: 347
Pages: 99-107
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Publication
25779930 | J:221610
 
First Author: Ng SK
Year: 2015
Journal: Exp Neurol
Title: Suppression of adenosine 2a receptor (A2aR)-mediated adenosine signaling improves disease phenotypes in a mouse model of amyotrophic lateral sclerosis.
Volume: 267
Pages: 115-22
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Publication
20678550 | J:165291
First Author: Li L
Year: 2010
Journal: Neuroscience
Title: Peripheral adenosine A2A receptors are involved in carrageenan-induced mechanical hyperalgesia in mice.
Volume: 170
Issue: 3
Pages: 923-8
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Publication
16916931 | J:112897
First Author: Ohta A
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: A2A adenosine receptor protects tumors from antitumor T cells.
Volume: 103
Issue: 35
Pages: 13132-7
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Publication
32998232 | J:304880
 
First Author: Troncoso F
Year: 2020
Journal: Int J Mol Sci
Title: Advantages in Wound Healing Process in Female Mice Require Upregulation A2A-Mediated Angiogenesis under the Stimulation of 17β-Estradiol.
Volume: 21
Issue: 19
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Publication
34813840 | J:332885
 
First Author: Li XC
Year: 2022
Journal: Exp Neurol
Title: Blockade of adenosine A(2A) receptor alleviates cognitive dysfunction after chronic exposure to intermittent hypoxia in mice.
Volume: 350
Pages: 113929
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Publication
11826134 | J:126975
First Author: Fredduzzi S
Year: 2002
Journal: J Neurosci
Title: Persistent behavioral sensitization to chronic L-DOPA requires A2A adenosine receptors.
Volume: 22
Issue: 3
Pages: 1054-62
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Publication
30866652 | J:292188
First Author: Borhani S
Year: 2019
Journal: FASEB J
Title: Adenosine A2A receptor (A2AR) activation triggers Akt signaling and enhances nuclear localization of β-catenin in osteoblasts.
Volume: 33
Issue: 6
Pages: 7555-7562
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Publication
18025187 | J:154815
First Author: Ohta A
Year: 2007
Journal: J Immunol
Title: 1,3,7-trimethylxanthine (caffeine) may exacerbate acute inflammatory liver injury by weakening the physiological immunosuppressive mechanism.
Volume: 179
Issue: 11
Pages: 7431-8
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Publication
15210754 | J:90811
First Author: Lukashev D
Year: 2004
Journal: J Immunol
Title: Cutting edge: Physiologic attenuation of proinflammatory transcription by the Gs protein-coupled A2A adenosine receptor in vivo.
Volume: 173
Issue: 1
Pages: 21-4
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Publication
12975473 | J:117981
First Author: Day YJ
Year: 2003
Journal: J Clin Invest
Title: Renal protection from ischemia mediated by A2A adenosine receptors on bone marrow-derived cells.
Volume: 112
Issue: 6
Pages: 883-91
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Publication
23093781 | J:194009
First Author: Li L
Year: 2012
Journal: J Clin Invest
Title: Dendritic cells tolerized with adenosine Aâ‚‚AR agonist attenuate acute kidney injury.
Volume: 122
Issue: 11
Pages: 3931-42
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Publication
16470403 | J:136509
First Author: Bilbao A
Year: 2006
Journal: Psychopharmacology (Berl)
Title: Absence of quasi-morphine withdrawal syndrome in adenosine A2A receptor knockout mice.
Volume: 185
Issue: 2
Pages: 160-8
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Publication
22639925 | J:190427
First Author: Yao SQ
Year: 2012
Journal: J Neurochem
Title: Genetic inactivation of the adenosine A(2A) receptor exacerbates brain damage in mice with experimental autoimmune encephalomyelitis.
Volume: 123
Issue: 1
Pages: 100-12
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Publication
26415936 | J:230594
First Author: Perez-Aso M
Year: 2016
Journal: FASEB J
Title: Adenosine A2A receptor plays an important role in radiation-induced dermal injury.
Volume: 30
Issue: 1
Pages: 457-65
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Publication
36038626 | J:327993
First Author: Xu X
Year: 2022
Journal: Sci Rep
Title: Adenosine A2A receptors control synaptic remodeling in the adult brain.
Volume: 12
Issue: 1
Pages: 14690
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Publication
23407968 | J:194258
First Author: Li H
Year: 2013
Journal: J Neurosci
Title: Adenosine and dopamine receptors coregulate photoreceptor coupling via gap junction phosphorylation in mouse retina.
Volume: 33
Issue: 7
Pages: 3135-50
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Publication
28377741 | J:311606
 
First Author: Yin SB
Year: 2017
Journal: Front Neurol
Title: Adenosine A2A Receptor Gene Knockout Prevents l-3,4-Dihydroxyphenylalanine-Induced Dyskinesia by Downregulation of Striatal GAD67 in 6-OHDA-Lesioned Parkinson's Mice.
Volume: 8
Pages: 88
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Publication
20367749 | J:163571
First Author: Dai SS
Year: 2010
Journal: J Neurochem
Title: Adenosine A2A receptors in both bone marrow cells and non-bone marrow cells contribute to traumatic brain injury.
Volume: 113
Issue: 6
Pages: 1536-44
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Publication
20484596 | J:164077
First Author: Zhou X
Year: 2010
Journal: Invest Ophthalmol Vis Sci
Title: Genetic deletion of the adenosine A2A receptor confers postnatal development of relative myopia in mice.
Volume: 51
Issue: 9
Pages: 4362-70
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Publication
15634932 | J:95830
First Author: Lappas CM
Year: 2005
Journal: J Immunol
Title: A2A adenosine receptor induction inhibits IFN-gamma production in murine CD4+ T cells.
Volume: 174
Issue: 2
Pages: 1073-80
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Publication
12700712 | J:106215
First Author: Chen JF
Year: 2003
Journal: Neuropsychopharmacology
Title: Inactivation of adenosine A2A receptors selectively attenuates amphetamine-induced behavioral sensitization.
Volume: 28
Issue: 6
Pages: 1086-95
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Publication
19785999 | J:157408
 
First Author: Zhou SJ
Year: 2009
Journal: Brain Res
Title: Preferential enhancement of working memory in mice lacking adenosine A(2A) receptors.
Volume: 1303
Pages: 74-83
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Publication
18703794 | J:157434
First Author: Scheibner KA
Year: 2009
Journal: Am J Respir Cell Mol Biol
Title: The adenosine a2a receptor inhibits matrix-induced inflammation in a novel fashion.
Volume: 40
Issue: 3
Pages: 251-9
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Publication
11780065 | J:111970
First Author: Ohta A
Year: 2001
Journal: Nature
Title: Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage.
Volume: 414
Issue: 6866
Pages: 916-20
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Publication
34536482 | J:313594
     
First Author: Welihinda A
Year: 2021
Journal: J Invest Dermatol
Title: Positive Allosteric Modulation of A2AR Alters Immune Cell Responses and Ameliorates Psoriasis-Like Dermatitis in Mice.
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Publication
34407410 | J:324790
First Author: Tsai CJ
Year: 2021
Journal: Cell Rep
Title: Cerebral capillary blood flow upsurge during REM sleep is mediated by A2a receptors.
Volume: 36
Issue: 7
Pages: 109558
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Publication
32052890 | J:291150
First Author: Castro CM
Year: 2020
Journal: FASEB J
Title: Adenosine A2A receptor (A2AR) stimulation enhances mitochondrial metabolism and mitigates reactive oxygen species-mediated mitochondrial injury.
Volume: 34
Issue: 4
Pages: 5027-5045
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Publication
14720203 | J:90090
First Author: Fink JS
Year: 2004
Journal: J Neurochem
Title: Genetic and pharmacological inactivation of the adenosine A2A receptor attenuates 3-nitropropionic acid-induced striatal damage.
Volume: 88
Issue: 3
Pages: 538-44
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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