Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:7266333 |
Assay Type: |
RT-PCR |
Annotation Date: |
2022-05-04 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684620 |
|
Stage: |
TS20 |
Assay Id: |
MGI:7266409 |
Age: |
embryonic day 12.0 |
|
|
Specimen Label: |
E12 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7266333 |
Assay Type: |
RT-PCR |
Annotation Date: |
2022-05-04 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684622 |
|
Stage: |
TS22 |
Assay Id: |
MGI:7266409 |
Age: |
embryonic day 14.0 |
|
|
Specimen Label: |
E14 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7266333 |
Assay Type: |
RT-PCR |
Annotation Date: |
2022-05-04 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684624 |
|
Stage: |
TS24 |
Assay Id: |
MGI:7266409 |
Age: |
embryonic day 16.0 |
|
|
Specimen Label: |
E16 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7266333 |
Assay Type: |
RT-PCR |
Annotation Date: |
2022-05-04 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684626 |
|
Stage: |
TS26 |
Assay Id: |
MGI:7266409 |
Age: |
embryonic day 18.0 |
|
|
Specimen Label: |
E18 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7266333 |
Assay Type: |
RT-PCR |
Annotation Date: |
2022-05-04 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684627 |
|
Stage: |
TS27 |
Assay Id: |
MGI:7266409 |
Age: |
postnatal day 1 |
|
|
Specimen Label: |
P1 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7266333 |
Assay Type: |
RT-PCR |
Annotation Date: |
2022-05-04 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7266409 |
Age: |
postnatal day 7 |
|
|
Specimen Label: |
P7 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7266333 |
Assay Type: |
RT-PCR |
Annotation Date: |
2022-05-04 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7266409 |
Age: |
postnatal day 21 |
|
|
Specimen Label: |
P21 |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7266333 |
Assay Type: |
RT-PCR |
Annotation Date: |
2022-05-04 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7266409 |
Age: |
postnatal day 100 |
|
|
Specimen Label: |
P100 |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7266333 |
Assay Type: |
RT-PCR |
Annotation Date: |
2022-05-04 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1636716 |
|
Stage: |
TS16 |
Assay Id: |
MGI:7266417 |
Age: |
embryonic day 10.0 |
|
|
Specimen Label: |
E10 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7266333 |
Assay Type: |
RT-PCR |
Annotation Date: |
2022-05-04 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737320 |
|
Stage: |
TS20 |
Assay Id: |
MGI:7266417 |
Age: |
embryonic day 12.0 |
|
|
Specimen Label: |
E12 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7266333 |
Assay Type: |
RT-PCR |
Annotation Date: |
2022-05-04 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737322 |
|
Stage: |
TS22 |
Assay Id: |
MGI:7266417 |
Age: |
embryonic day 14.0 |
|
|
Specimen Label: |
E14 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7266333 |
Assay Type: |
RT-PCR |
Annotation Date: |
2022-05-04 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737324 |
|
Stage: |
TS24 |
Assay Id: |
MGI:7266417 |
Age: |
embryonic day 16.0 |
|
|
Specimen Label: |
E16 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7266333 |
Assay Type: |
RT-PCR |
Annotation Date: |
2022-05-04 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737326 |
|
Stage: |
TS26 |
Assay Id: |
MGI:7266417 |
Age: |
embryonic day 18.0 |
|
|
Specimen Label: |
E18 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7266333 |
Assay Type: |
RT-PCR |
Annotation Date: |
2022-05-04 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737327 |
|
Stage: |
TS27 |
Assay Id: |
MGI:7266417 |
Age: |
postnatal day 1 |
|
|
Specimen Label: |
P1 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7266333 |
Assay Type: |
RT-PCR |
Annotation Date: |
2022-05-04 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7266417 |
Age: |
postnatal day 7 |
|
|
Specimen Label: |
P7 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7266333 |
Assay Type: |
RT-PCR |
Annotation Date: |
2022-05-04 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7266417 |
Age: |
postnatal day 21 |
|
|
Specimen Label: |
P21 |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7266333 |
Assay Type: |
RT-PCR |
Annotation Date: |
2022-05-04 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7266417 |
Age: |
postnatal day 100 |
|
|
Specimen Label: |
P100 |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
Journal: |
Database Download |
Title: |
Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Baumann P |
Year: |
2010 |
Journal: |
FEBS Lett |
Title: |
Pot1 and telomere maintenance. |
Volume: |
584 |
Issue: |
17 |
Pages: |
3779-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Trujillo KM |
Year: |
2005 |
Journal: |
J Biol Chem |
Title: |
Extended DNA binding site in Pot1 broadens sequence specificity to allow recognition of heterogeneous fission yeast telomeres. |
Volume: |
280 |
Issue: |
10 |
Pages: |
9119-28 |
|
•
•
•
•
•
|
Publication |
First Author: |
Surovtseva YV |
Year: |
2007 |
Journal: |
EMBO J |
Title: |
Arabidopsis POT1 associates with the telomerase RNP and is required for telomere maintenance. |
Volume: |
26 |
Issue: |
15 |
Pages: |
3653-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu Y |
Year: |
2013 |
Journal: |
J Proteome Res |
Title: |
Novel phosphorylation sites in the S. cerevisiae Cdc13 protein reveal new targets for telomere length regulation. |
Volume: |
12 |
Issue: |
1 |
Pages: |
316-27 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
In most eukaryotes, their chromosome ends are composed of a single stranded overhang that contains GT-rich repeats and are bound by telomerase ribonucleoproteins (RNPs).This entry represents a group of telomere binding proteins, including the protection of telomeres protein 1 (POT1) from humans/fission yeast/plants, the telomere end binding proteins (TEBP) alpha from the hypotrichous ciliate Oxytricha nova and Cdc13 from Saccharomyces cerevisiae. They are ribonucleoproteins (RNPs) that play an important role in telomere maintenance, but the precise roles played in end protection and telomere length regulation seem to vary considerably between organisms [, ]. In fission yeast, POT1 prevents access of telomerase to the 3'-end and protects against exonucleolytic degradation []. However, in humans, POT1 might function predominantly in telomere length regulation rather than in the protection of telomeres []. In Arabidopsis, there are several POT-like proteins, including POT1a, POT1b and POT1c []. POT1a and POT1b are components of telomerase rather than telomere capping components []. In Saccharomyces cerevisiae an OB-fold containing protein called Cdc13 plays a similar role as POT1, such as single-stranded G-rich telomeric DNA binding and telomere maintenance [, ]. |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
640
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
133
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
640
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
352
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
538
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
623
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
325
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Miyoshi T |
Year: |
2008 |
Journal: |
Science |
Title: |
Fission yeast Pot1-Tpp1 protects telomeres and regulates telomere length. |
Volume: |
320 |
Issue: |
5881 |
Pages: |
1341-4 |
|
•
•
•
•
•
|