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Search results 301 to 400 out of 405 for Men1

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Type Details Score
Publication
First Author: Lin W
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1.
Volume: 108
Issue: 33
Pages: 13379-86
Publication
First Author: Watanabe Y
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Trithorax complex component Menin controls differentiation and maintenance of T helper 17 cells.
Volume: 111
Issue: 35
Pages: 12829-34
Publication
First Author: Wasylishen AR
Year: 2020
Journal: Sci Adv
Title: Daxx maintains endogenous retroviral silencing and restricts cellular plasticity in vivo.
Volume: 6
Issue: 32
Pages: eaba8415
Publication
First Author: Wang P
Year: 2009
Journal: Mol Cell Biol
Title: Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II.
Volume: 29
Issue: 22
Pages: 6074-85
Publication
First Author: Li BE
Year: 2013
Journal: Blood
Title: Distinct pathways regulated by menin and by MLL1 in hematopoietic stem cells and developing B cells.
Volume: 122
Issue: 12
Pages: 2039-46
Publication
First Author: Wijeweera A
Year: 2015
Journal: Biochim Biophys Acta
Title: Gonadotropin gene transcription is activated by menin-mediated effects on the chromatin.
Volume: 1849
Issue: 3
Pages: 328-41
Publication
First Author: Donangelo I
Year: 2005
Journal: J Endocrinol Invest
Title: Pathophysiology of pituitary adenomas.
Volume: 28
Issue: 11 Suppl International
Pages: 100-5
Publication
First Author: Hughes E
Year: 2011
Journal: Endocrinology
Title: Participation of Akt, menin, and p21 in pregnancy-induced beta-cell proliferation.
Volume: 152
Issue: 3
Pages: 847-55
Publication
First Author: Zhu LY
Year: 2022
Journal: Cancer Res
Title: Loss of MLL Induces Epigenetic Dysregulation of Rasgrf1 to Attenuate Kras-Driven Lung Tumorigenesis.
Volume: 82
Issue: 22
Pages: 4153-4163
Publication
First Author: Jones M
Year: 2015
Journal: J Clin Invest
Title: Ash1l controls quiescence and self-renewal potential in hematopoietic stem cells.
Volume: 125
Issue: 5
Pages: 2007-20
Publication
First Author: Yokoyama A
Year: 2011
Journal: J Cell Sci
Title: Proteolytically cleaved MLL subunits are susceptible to distinct degradation pathways.
Volume: 124
Issue: Pt 13
Pages: 2208-19
Publication
First Author: Terranova R
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Histone and DNA methylation defects at Hox genes in mice expressing a SET domain-truncated form of Mll.
Volume: 103
Issue: 17
Pages: 6629-34
Publication
First Author: Onodera A
Year: 2010
Journal: J Exp Med
Title: STAT6-mediated displacement of polycomb by trithorax complex establishes long-term maintenance of GATA3 expression in T helper type 2 cells.
Volume: 207
Issue: 11
Pages: 2493-506
Publication
First Author: Engleka KA
Year: 2007
Journal: Dev Biol
Title: Menin is required in cranial neural crest for palatogenesis and perinatal viability.
Volume: 311
Issue: 2
Pages: 524-37
Publication
First Author: Sowa H
Year: 2004
Journal: J Biol Chem
Title: Menin is required for bone morphogenetic protein 2- and transforming growth factor beta-regulated osteoblastic differentiation through interaction with Smads and Runx2.
Volume: 279
Issue: 39
Pages: 40267-75
Publication
First Author: Cho YW
Year: 2007
Journal: J Biol Chem
Title: PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.
Volume: 282
Issue: 28
Pages: 20395-406
Publication
First Author: Chamberlain CE
Year: 2014
Journal: J Clin Invest
Title: Menin determines K-RAS proliferative outputs in endocrine cells.
Volume: 124
Issue: 9
Pages: 4093-101
Publication
First Author: Smart NG
Year: 2006
Journal: PLoS Biol
Title: Conditional expression of Smad7 in pancreatic beta cells disrupts TGF-beta signaling and induces reversible diabetes mellitus.
Volume: 4
Issue: 2
Pages: e39
Publication
First Author: Pan FC
Year: 2015
Journal: Development
Title: Inactivating the permanent neonatal diabetes gene Mnx1 switches insulin-producing β-cells to a δ-like fate and reveals a facultative proliferative capacity in aged β-cells.
Volume: 142
Issue: 21
Pages: 3637-48
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication        
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
Publication
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication  
First Author: Agarwal SK
Year: 2004
Journal: Ann N Y Acad Sci
Title: Molecular pathology of the MEN1 gene.
Volume: 1014
Pages: 189-98
HT Experiment
Series Id: GSE29674
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Xu J
Year: 2023
Journal: Cancer Res
Title: MEN1 Degradation Induced by Neddylation and the CUL4B-DCAF7 Axis Promotes Pancreatic Neuroendocrine Tumor Progression.
Volume: 83
Issue: 13
Pages: 2226-2247
Publication
First Author: Rochelle JM
Year: 1992
Journal: Genomics
Title: A linkage map of mouse chromosome 19: definition of comparative mapping relationships with human chromosomes 10 and 11 including the MEN1 locus.
Volume: 14
Issue: 1
Pages: 26-31
Publication
First Author: Gobl AE
Year: 1995
Journal: Cytogenet Cell Genet
Title: Assignment of the mouse homologue of a human MEN1 candidate gene, phospholipase C-beta 3 (Plcb3), to chromosome region 19B by FISH.
Volume: 71
Issue: 3
Pages: 257-9
Allele
Name: multiple endocrine neoplasia 1; targeted mutation 1, Zhao-Qi Wang
Allele Type: Targeted
Attribute String: Null/knockout
Genotype
Symbol: Men1/Men1<+>
Background: involves: 129/Sv * 129P2/OlaHsd
Zygosity: ht
Has Mutant Allele: true
HT Experiment
Series Id: GSE26978
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Allele
Name: multiple endocrine neoplasia 1; targeted mutation 1, Zhao-Qi Wang
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Allele
Name: multiple endocrine neoplasia 1; targeted mutation 1, Judy S Crabtree
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout
Allele
Name: multiple endocrine neoplasia 1; targeted mutation 1, Graham F Kay
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Allele
Name: multiple endocrine neoplasia 1; targeted mutation 1, Rajesh V Thakker
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: multiple endocrine neoplasia 1; targeted mutation 1.1, Graham F Kay
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: multiple endocrine neoplasia 1; targeted mutation 2.1, Graham F Kay
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: multiple endocrine neoplasia 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Protein
Organism: Mus musculus/domesticus
Length: 653  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 639  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 548  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 611  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 64  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 576  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 616  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 108  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 88  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 135  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 617  
Fragment?: false
Publication
First Author: Yaguchi H
Year: 2002
Journal: J Biol Chem
Title: Menin, the multiple endocrine neoplasia type 1 gene product, exhibits GTP-hydrolyzing activity in the presence of the tumor metastasis suppressor nm23.
Volume: 277
Issue: 41
Pages: 38197-204
Publication
First Author: Zhang H
Year: 2011
Journal: Chin Med J (Engl)
Title: Menin expression is regulated by transforming growth factor beta signaling in leukemia cells.
Volume: 124
Issue: 10
Pages: 1556-62
Protein Domain
Type: Family
Description: The tumour suppressor gene MEN1 is mutated in patients with a dominantly inherited tumour syndrome, multiple endocrine neoplasia type 1 (MEN1) []. The MEN1 gene encodes a protein known as Menin, which is located predominantly in the nucleus. Menin has been shown to interact with the mixed lineage leukemia (MLL) protein, a histone H3 lysine 4 methyltransferase, and plays a critical role in hematopoiesis and leukemogenesis [].
Genotype
Symbol: Men1/Men1 Tg(Ins2-cre)23Herr/?
Background: involves: 129P2/OlaHsd * C57BL/6J * CBA/J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Men1/Men1<+>
Background: involves: 129T2/SvEms * C57BL/6
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Men1/Men1<+>
Background: involves: 129T2/SvEms * C57BL/6
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Men1/Men1 Tg(Ins2-cre)25Mgn/?
Background: involves: 129T2/SvEms * C57BL/6 * C57BL/6J * DBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Men1/Men1 Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129S6/SvEvTac * C57BL/6 * CBA * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Men1/Men1<+>
Background: involves: 129 * C57BL/6
Zygosity: ht
Has Mutant Allele: true
DO Term
Strain
Attribute String: targeted mutation, mutant strain, coisogenic
Strain
Attribute String: targeted mutation, mutant stock
Genotype
Symbol: Men1/Men1
Background: either: (involves: 129/Sv * 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6)
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Men1/Men1
Background: involves: 129 * 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Men1/Men1<+>
Background: involves: 129 * 129P2/OlaHsd * C57BL/6
Zygosity: ht
Has Mutant Allele: true
Publication  
First Author: Li JWY
Year: 2018
Journal: Mol Cell Endocrinol
Title: MENIN loss as a tissue-specific driver of tumorigenesis.
Volume: 469
Pages: 98-106
Publication
First Author: Lagercrantz J
Year: 1996
Journal: Biochem Biophys Res Commun
Title: Sequence and expression of the mouse homologue to human phospholipase C beta3 neighboring gene.
Volume: 223
Issue: 2
Pages: 335-40
Publication
First Author: Ohki R
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: PHLDA3 is a novel tumor suppressor of pancreatic neuroendocrine tumors.
Volume: 111
Issue: 23
Pages: E2404-13
Publication
First Author: Toda T
Year: 1994
Journal: Hum Mol Genet
Title: Isolation and characterization of a novel gene encoding nuclear protein at a locus (D11S636) tightly linked to multiple endocrine neoplasia type 1 (MEN1).
Volume: 3
Issue: 3
Pages: 465-70
Publication
First Author: Guru SC
Year: 1997
Journal: Genome Res
Title: A transcript map for the 2.8-Mb region containing the multiple endocrine neoplasia type 1 locus.
Volume: 7
Issue: 7
Pages: 725-35
Publication
First Author: Ebrahimi S
Year: 1998
Journal: Gene
Title: Genomic organization and cloning of the human homologue of murine Sipa-1.
Volume: 214
Issue: 1-2
Pages: 215-21
Publication
First Author: Gracanin A
Year: 2009
Journal: Cancer Res
Title: Tissue selectivity in multiple endocrine neoplasia type 1-associated tumorigenesis.
Volume: 69
Issue: 16
Pages: 6371-4
Publication  
First Author: Lines KE
Year: 2016
Journal: Mol Cell Endocrinol
Title: Animal models of pituitary neoplasia.
Volume: 421
Pages: 68-81
Publication
First Author: Chung DC
Year: 1998
Journal: Cancer Res
Title: Localization of putative tumor suppressor loci by genome-wide allelotyping in human pancreatic endocrine tumors.
Volume: 58
Issue: 16
Pages: 3706-11
Publication
First Author: Scacheri PC
Year: 2004
Journal: Cancer Res
Title: Pancreatic insulinomas in multiple endocrine neoplasia, type I knockout mice can develop in the absence of chromosome instability or microsatellite instability.
Volume: 64
Issue: 19
Pages: 7039-44
Publication
First Author: Jonkers YM
Year: 2007
Journal: Biochim Biophys Acta
Title: Molecular alterations during insulinoma tumorigenesis.
Volume: 1775
Issue: 2
Pages: 313-32
Publication
First Author: Korsisaari N
Year: 2008
Journal: Clin Cancer Res
Title: Blocking vascular endothelial growth factor-A inhibits the growth of pituitary adenomas and lowers serum prolactin level in a mouse model of multiple endocrine neoplasia type 1.
Volume: 14
Issue: 1
Pages: 249-58