This entry represents the WD repeat BOP1/Erb1 family. Members of this family are ribosome biogenesis proteins. In humans and mice, BOP1 is a component of the PeBoW complex (composed of BOP1, PES1 and WDR12), which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome []. In Saccharomyces cerevisiae, Erb1 is a component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome [].
