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Search results 1 to 100 out of 113 for Ppt1

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Category: Publication
Type Details Score
Publication
First Author: Ou P
Year: 2019
Journal: J Exp Med
Title: Thioesterase PPT1 balances viral resistance and efficient T cell crosspriming in dendritic cells.
Volume: 216
Issue: 9
Pages: 2091-2112
Publication  
First Author: Zhang X
Year: 2022
Journal: Int J Mol Sci
Title: Seizures in PPT1 Knock-In Mice Are Associated with Inflammatory Activation of Microglia.
Volume: 23
Issue: 10
Publication
First Author: Gupta P
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Disruption of PPT1 or PPT2 causes neuronal ceroid lipofuscinosis in knockout mice.
Volume: 98
Issue: 24
Pages: 13566-71
Publication
First Author: Aby E
Year: 2013
Journal: Fly (Austin)
Title: Mutations in palmitoyl-protein thioesterase 1 alter exocytosis and endocytosis at synapses in Drosophila larvae.
Volume: 7
Issue: 4
Pages: 267-79
Publication
First Author: Hawkins-Salsbury JA
Year: 2013
Journal: Biochim Biophys Acta
Title: Pathogenesis and therapies for infantile neuronal ceroid lipofuscinosis (infantile CLN1 disease).
Volume: 1832
Issue: 11
Pages: 1906-9
Publication
First Author: Zhang Z
Year: 2007
Journal: Hum Mol Genet
Title: Production of lysophosphatidylcholine by cPLA2 in the brain of mice lacking PPT1 is a signal for phagocyte infiltration.
Volume: 16
Issue: 7
Pages: 837-47
Publication
First Author: Lyly A
Year: 2008
Journal: Hum Mol Genet
Title: Deficiency of the INCL protein Ppt1 results in changes in ectopic F1-ATP synthase and altered cholesterol metabolism.
Volume: 17
Issue: 10
Pages: 1406-17
Publication
First Author: Sarkar C
Year: 2013
Journal: Nat Neurosci
Title: Neuroprotection and lifespan extension in Ppt1(-/-) mice by NtBuHA: therapeutic implications for INCL.
Volume: 16
Issue: 11
Pages: 1608-17
Publication
First Author: Tamaki SJ
Year: 2009
Journal: Cell Stem Cell
Title: Neuroprotection of host cells by human central nervous system stem cells in a mouse model of infantile neuronal ceroid lipofuscinosis.
Volume: 5
Issue: 3
Pages: 310-9
Publication
First Author: Kielar C
Year: 2007
Journal: Neurobiol Dis
Title: Successive neuron loss in the thalamus and cortex in a mouse model of infantile neuronal ceroid lipofuscinosis.
Volume: 25
Issue: 1
Pages: 150-62
Publication
First Author: Jalanko A
Year: 2005
Journal: Neurobiol Dis
Title: Mice with Ppt1Deltaex4 mutation replicate the INCL phenotype and show an inflammation-associated loss of interneurons.
Volume: 18
Issue: 1
Pages: 226-41
Publication
First Author: Hu J
Year: 2012
Journal: Mol Genet Metab
Title: Intravenous high-dose enzyme replacement therapy with recombinant palmitoyl-protein thioesterase reduces visceral lysosomal storage and modestly prolongs survival in a preclinical mouse model of infantile neuronal ceroid lipofuscinosis.
Volume: 107
Issue: 1-2
Pages: 213-21
Publication
First Author: Gorenberg EL
Year: 2022
Journal: PLoS Biol
Title: Identification of substrates of palmitoyl protein thioesterase 1 highlights roles of depalmitoylation in disulfide bond formation and synaptic function.
Volume: 20
Issue: 3
Pages: e3001590
Publication
First Author: Zhang Z
Year: 2006
Journal: Hum Mol Genet
Title: Palmitoyl-protein thioesterase-1 deficiency mediates the activation of the unfolded protein response and neuronal apoptosis in INCL.
Volume: 15
Issue: 2
Pages: 337-46
Publication
First Author: Segal-Salto M
Year: 2017
Journal: Hum Mol Genet
Title: Proteomics insights into infantile neuronal ceroid lipofuscinosis (CLN1) point to the involvement of cilia pathology in the disease.
Volume: 26
Issue: 9
Pages: 1678
Publication
First Author: Kim SJ
Year: 2006
Journal: Hum Mol Genet
Title: Palmitoyl-protein thioesterase-1 deficiency leads to the activation of caspase-9 and contributes to rapid neurodegeneration in INCL.
Volume: 15
Issue: 10
Pages: 1580-6
Publication
First Author: Kim SJ
Year: 2008
Journal: J Clin Invest
Title: Palmitoyl protein thioesterase-1 deficiency impairs synaptic vesicle recycling at nerve terminals, contributing to neuropathology in humans and mice.
Volume: 118
Issue: 9
Pages: 3075-86
Publication
First Author: Bouchelion A
Year: 2014
Journal: Ann Clin Transl Neurol
Title: Mice homozygous for c.451C>T mutation in Cln1 gene recapitulate INCL phenotype.
Volume: 1
Issue: 12
Pages: 1006-23
Publication
First Author: Shyng C
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Synergistic effects of treating the spinal cord and brain in CLN1 disease.
Volume: 114
Issue: 29
Pages: E5920-E5929
Publication
First Author: Atiskova Y
Year: 2019
Journal: Sci Rep
Title: Mice deficient in the lysosomal enzyme palmitoyl-protein thioesterase 1 (PPT1) display a complex retinal phenotype.
Volume: 9
Issue: 1
Pages: 14185
Publication
First Author: Zhao W
Year: 2019
Journal: Mol Reprod Dev
Title: Functional importance of palmitoyl protein thioesterase 1 (PPT1) expression by Sertoli cells in mediating cholesterol metabolism and maintenance of sperm quality.
Volume: 86
Issue: 8
Pages: 984-998
Publication
First Author: Miller JN
Year: 2015
Journal: Hum Mol Genet
Title: The novel Cln1(R151X) mouse model of infantile neuronal ceroid lipofuscinosis (INCL) for testing nonsense suppression therapy.
Volume: 24
Issue: 1
Pages: 185-96
Publication
First Author: Ahtiainen L
Year: 2003
Journal: J Comp Neurol
Title: Palmitoyl protein thioesterase 1 is targeted to the axons in neurons.
Volume: 455
Issue: 3
Pages: 368-77
Publication
First Author: Ni H
Year: 2024
Journal: Nat Commun
Title: Cyclical palmitoylation regulates TLR9 signalling and systemic autoimmunity in mice.
Volume: 15
Issue: 1
Pages: 1
Publication
First Author: Lange J
Year: 2018
Journal: Acta Neuropathol Commun
Title: Compromised astrocyte function and survival negatively impact neurons in infantile neuronal ceroid lipofuscinosis.
Volume: 6
Issue: 1
Pages: 74
Publication
First Author: Khaibullina A
Year: 2012
Journal: PLoS One
Title: In a model of Batten disease, palmitoyl protein thioesterase-1 deficiency is associated with brown adipose tissue and thermoregulation abnormalities.
Volume: 7
Issue: 11
Pages: e48733
Publication
First Author: Ahtiainen L
Year: 2006
Journal: Exp Cell Res
Title: Palmitoyl protein thioesterase 1 (PPT1) deficiency causes endocytic defects connected to abnormal saposin processing.
Volume: 312
Issue: 9
Pages: 1540-53
Publication    
First Author: Koster KP
Year: 2019
Journal: Elife
Title: Developmental NMDA receptor dysregulation in the infantile neuronal ceroid lipofuscinosis mouse model.
Volume: 8
Publication
First Author: Virmani T
Year: 2005
Journal: Neurobiol Dis
Title: Progressively reduced synaptic vesicle pool size in cultured neurons derived from neuronal ceroid lipofuscinosis-1 knockout mice.
Volume: 20
Issue: 2
Pages: 314-23
Publication  
First Author: Yuan W
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: GFAP hyperpalmitoylation exacerbates astrogliosis and neurodegenerative pathology in PPT1-deficient mice.
Volume: 118
Issue: 13
Publication
First Author: Sarkar C
Year: 2020
Journal: J Inherit Metab Dis
Title: Cln1-mutations suppress Rab7-RILP interaction and impair autophagy contributing to neuropathology in a mouse model of infantile neuronal ceroid lipofuscinosis.
Volume: 43
Issue: 5
Pages: 1082-1101
Publication
First Author: Macauley SL
Year: 2011
Journal: J Neurosci
Title: The role of attenuated astrocyte activation in infantile neuronal ceroid lipofuscinosis.
Volume: 31
Issue: 43
Pages: 15575-85
Publication
First Author: Tardy C
Year: 2009
Journal: Biochim Biophys Acta
Title: Palmitoyl protein thioesterase 1 modulates tumor necrosis factor alpha-induced apoptosis.
Volume: 1793
Issue: 7
Pages: 1250-8
Publication
First Author: Perez-Canamas A
Year: 2021
Journal: Brain Commun
Title: Fronto-temporal dementia risk gene TMEM106B has opposing effects in different lysosomal storage disorders.
Volume: 3
Issue: 1
Pages: fcaa200
Publication  
First Author: Lyly A
Year: 2009
Journal: BMC Cell Biol
Title: Novel interactions of CLN5 support molecular networking between Neuronal Ceroid Lipofuscinosis proteins.
Volume: 10
Pages: 83
Publication
First Author: Cho SK
Year: 2005
Journal: Glycobiology
Title: Characterization of lipid-linked oligosaccharide accumulation in mouse models of Batten disease.
Volume: 15
Issue: 6
Pages: 637-48
Publication
First Author: Zhang Z
Year: 1999
Journal: Gene
Title: Palmitoyl-protein thioesterase gene expression in the developing mouse brain and retina: implications for early loss of vision in infantile neuronal ceroid lipofuscinosis.
Volume: 231
Issue: 1-2
Pages: 203-11
Publication
First Author: Berve K
Year: 2020
Journal: J Neuroinflammation
Title: Sex- and region-biased depletion of microglia/macrophages attenuates CLN1 disease in mice.
Volume: 17
Issue: 1
Pages: 323
Publication  
First Author: Sapir T
Year: 2019
Journal: Front Cell Neurosci
Title: The Interactome of Palmitoyl-Protein Thioesterase 1 (PPT1) Affects Neuronal Morphology and Function.
Volume: 13
Pages: 92
Publication
First Author: Bible E
Year: 2004
Journal: Neurobiol Dis
Title: Regional and cellular neuropathology in the palmitoyl protein thioesterase-1 null mutant mouse model of infantile neuronal ceroid lipofuscinosis.
Volume: 16
Issue: 2
Pages: 346-59
Publication  
First Author: Sadhukhan T
Year: 2021
Journal: Biochem Biophys Res Commun
Title: Ablation of microRNA-155 and neuroinflammation in a mouse model of CLN1-disease.
Volume: 571
Pages: 137-144
Publication
First Author: Saha A
Year: 2012
Journal: Hum Mol Genet
Title: The blood-brain barrier is disrupted in a mouse model of infantile neuronal ceroid lipofuscinosis: amelioration by resveratrol.
Volume: 21
Issue: 10
Pages: 2233-44
Publication
First Author: Nelvagal HR
Year: 2020
Journal: Sci Rep
Title: Comparative proteomic profiling reveals mechanisms for early spinal cord vulnerability in CLN1 disease.
Volume: 10
Issue: 1
Pages: 15157
Publication  
First Author: Dearborn JT
Year: 2015
Journal: Sci Rep
Title: Comprehensive functional characterization of murine infantile Batten disease including Parkinson-like behavior and dopaminergic markers.
Volume: 5
Pages: 12752
Publication
First Author: Macauley SL
Year: 2009
Journal: Exp Neurol
Title: Cerebellar pathology and motor deficits in the palmitoyl protein thioesterase 1-deficient mouse.
Volume: 217
Issue: 1
Pages: 124-35
Publication  
First Author: Bagh MB
Year: 2017
Journal: Nat Commun
Title: Misrouting of v-ATPase subunit V0a1 dysregulates lysosomal acidification in a neurodegenerative lysosomal storage disease model.
Volume: 8
Pages: 14612
Publication
First Author: Peviani M
Year: 2023
Journal: EMBO Mol Med
Title: An innovative hematopoietic stem cell gene therapy approach benefits CLN1 disease in the mouse model.
Volume: 15
Issue: 4
Pages: e15968
Publication
First Author: Dearborn JT
Year: 2022
Journal: Sci Rep
Title: Effects of chronic cannabidiol in a mouse model of naturally occurring neuroinflammation, neurodegeneration, and spontaneous seizures.
Volume: 12
Issue: 1
Pages: 11286
Publication
First Author: Macauley SL
Year: 2014
Journal: J Neurosci
Title: An anti-neuroinflammatory that targets dysregulated glia enhances the efficacy of CNS-directed gene therapy in murine infantile neuronal ceroid lipofuscinosis.
Volume: 34
Issue: 39
Pages: 13077-82
Publication
First Author: Finn R
Year: 2013
Journal: J Child Neurol
Title: Treatment of the Ppt1(-/-) mouse model of infantile neuronal ceroid lipofuscinosis with the N-methyl-D-aspartate (NMDA) receptor antagonist memantine.
Volume: 28
Issue: 9
Pages: 1159-68
Publication
First Author: Ahtiainen L
Year: 2007
Journal: Neurobiol Dis
Title: Palmitoyl protein thioesterase 1 (Ppt1)-deficient mouse neurons show alterations in cholesterol metabolism and calcium homeostasis prior to synaptic dysfunction.
Volume: 28
Issue: 1
Pages: 52-64
Publication
First Author: Isosomppi J
Year: 1999
Journal: Brain Res Dev Brain Res
Title: Developmental expression of palmitoyl protein thioesterase in normal mice.
Volume: 118
Issue: 1-2
Pages: 1-11
Publication
First Author: Salonen T
Year: 1998
Journal: Genome Res
Title: Mouse palmitoyl protein thioesterase: gene structure and expression of cDNA.
Volume: 8
Issue: 7
Pages: 724-30
Publication  
First Author: von Schantz C
Year: 2008
Journal: BMC Genomics
Title: Brain gene expression profiles of Cln1 and Cln5 deficient mice unravels common molecular pathways underlying neuronal degeneration in NCL diseases.
Volume: 9
Pages: 146
Publication
First Author: Blom T
Year: 2013
Journal: Dis Model Mech
Title: Exacerbated neuronal ceroid lipofuscinosis phenotype in Cln1/5 double-knockout mice.
Volume: 6
Issue: 2
Pages: 342-57
Publication
First Author: Wei H
Year: 2011
Journal: Hum Mol Genet
Title: Disruption of adaptive energy metabolism and elevated ribosomal p-S6K1 levels contribute to INCL pathogenesis: partial rescue by resveratrol.
Volume: 20
Issue: 6
Pages: 1111-21
Publication
First Author: Bond M
Year: 2013
Journal: Biochim Biophys Acta
Title: Use of model organisms for the study of neuronal ceroid lipofuscinosis.
Volume: 1832
Issue: 11
Pages: 1842-65
Publication
First Author: Saha A
Year: 2008
Journal: FEBS Lett
Title: RAGE signaling contributes to neuroinflammation in infantile neuronal ceroid lipofuscinosis.
Volume: 582
Issue: 27
Pages: 3823-31
Publication
First Author: Chen P
Year: 2015
Journal: J Invest Dermatol
Title: Lack of Collagen VI Promotes Wound-Induced Hair Growth.
Volume: 135
Issue: 10
Pages: 2358-2367
Publication
First Author: Finn R
Year: 2012
Journal: J Neurosci Res
Title: Altered glutamate receptor function in the cerebellum of the Ppt1-/- mouse, a murine model of infantile neuronal ceroid lipofuscinosis.
Volume: 90
Issue: 2
Pages: 367-75
Publication
First Author: Kielar C
Year: 2009
Journal: Hum Mol Genet
Title: Molecular correlates of axonal and synaptic pathology in mouse models of Batten disease.
Volume: 18
Issue: 21
Pages: 4066-80
Publication
First Author: Elshatory Y
Year: 2003
Journal: FEBS Lett
Title: Early changes in gene expression in two models of Batten disease.
Volume: 538
Issue: 1-3
Pages: 207-12
Publication
First Author: Sapkota D
Year: 2019
Journal: Cell Rep
Title: Cell-Type-Specific Profiling of Alternative Translation Identifies Regulated Protein Isoform Variation in the Mouse Brain.
Volume: 26
Issue: 3
Pages: 594-607.e7
Publication
First Author: Hersrud SL
Year: 2016
Journal: Biochim Biophys Acta
Title: Antigen presenting cell abnormalities in the Cln3(-/-) mouse model of juvenile neuronal ceroid lipofuscinosis.
Volume: 1862
Issue: 7
Pages: 1324-36
Publication
First Author: Wendt KD
Year: 2005
Journal: Behav Brain Res
Title: Behavioral assessment in mouse models of neuronal ceroid lipofuscinosis using a light-cued T-maze.
Volume: 161
Issue: 2
Pages: 175-82
Publication
First Author: Groh J
Year: 2016
Journal: Glia
Title: Sialoadhesin promotes neuroinflammation-related disease progression in two mouse models of CLN disease.
Volume: 64
Issue: 5
Pages: 792-809
Publication
First Author: Palmer DN
Year: 2013
Journal: Biochim Biophys Acta
Title: NCL disease mechanisms.
Volume: 1832
Issue: 11
Pages: 1882-93
Publication  
First Author: Minye HM
Year: 2016
Journal: Data Brief
Title: Data on characterizing the gene expression patterns of neuronal ceroid lipofuscinosis genes: CLN1, CLN2, CLN3, CLN5 and their association to interneuron and neurotransmission markers: Parvalbumin and Somatostatin.
Volume: 8
Pages: 741-9
Publication
First Author: Fehr C
Year: 2002
Journal: J Neurosci
Title: Congenic mapping of alcohol and pentobarbital withdrawal liability loci to a <1 centimorgan interval of murine chromosome 4: identification of Mpdz as a candidate gene.
Volume: 22
Issue: 9
Pages: 3730-8
Publication
First Author: Ottolenghi C
Year: 2005
Journal: Hum Mol Genet
Title: Foxl2 is required for commitment to ovary differentiation.
Volume: 14
Issue: 14
Pages: 2053-62
Publication
First Author: Wu D
Year: 2019
Journal: J Neurosci
Title: A Role for Sensory end Organ-Derived Signals in Regulating Muscle Spindle Proprioceptor Phenotype.
Volume: 39
Issue: 22
Pages: 4252-4267
Publication  
First Author: Collin GB
Year: 2020
Journal: Cells
Title: Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.
Volume: 9
Issue: 4
Publication      
First Author: The Jackson Laboratory Backcross DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX BSS Panel Mapping Data
Publication        
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
Publication
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference