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Search results 1 to 100 out of 504 for Vcp

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Type Details Score
Gene
7415 | VCP
Type: gene
Organism: human
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Gene
327197 | vcp
Type: gene
Organism: zebrafish
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Gene
698707 | VCP
Type: gene
Organism: macaque, rhesus
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Gene
448177 | vcp
Type: gene
Organism: frog, western clawed
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Gene
key_33750 | VCP
Type: gene
Organism: pig, domestic
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Gene
116643 | Vcp
Type: gene
Organism: rat
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Gene
747490 | VCP
Type: gene
Organism: chimpanzee
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Gene
481590 | VCP
Type: gene
Organism: dog, domestic
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Gene
507345 | VCP
Type: gene
Organism: cattle
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Gene
427410 | VCP
Type: gene
Organism: chicken
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Protein Coding Gene
MGI:99919 | Vcp
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
- | J:263736
     
First Author: Clemen C
Year: 2018
Journal: MGI Direct Data Submission
Title: VCP mouse model
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Gene
4931 | NVL
Type: gene
Organism: human
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Gene
258010 | SVIP
Type: gene
Organism: human
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Publication
35414105 | J:327492
First Author: Zhu J
Year: 2022
Journal: Mol Neurodegener
Title: VCP suppresses proteopathic seeding in neurons.
Volume: 17
Issue: 1
Pages: 30
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GXD Expression
GXD Expression
 
Probe: MGI:976159
Assay Type: RNA in situ
Annotation Date: 2009-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4354783
Age: embryonic day 14.5
Note: Expression is present in the upper and lower cortical plate.
Specimen Label: Table S5 - Vcp
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:976159
Assay Type: RNA in situ
Annotation Date: 2009-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4354783
Age: embryonic day 14.5
Specimen Label: Table S5 - Vcp
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:976159
Assay Type: RNA in situ
Annotation Date: 2009-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4354783
Age: embryonic day 14.5
Specimen Label: Table S5 - Vcp
Detected: true
Specimen Num: 1
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Publication
33004675 | J:297654
 
First Author: Darwich NF
Year: 2020
Journal: Science
Title: Autosomal dominant VCP hypomorph mutation impairs disaggregation of PHF-tau.
Volume: 370
Issue: 6519
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Publication
34289347 | J:324879
First Author: Wani A
Year: 2021
Journal: Cell Rep
Title: Neuronal VCP loss of function recapitulates FTLD-TDP pathology.
Volume: 36
Issue: 3
Pages: 109399
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Publication
26086101 | J:228679
First Author: Clemen CS
Year: 2015
Journal: Biochem Biophys Res Commun
Title: VCP and PSMF1: Antagonistic regulators of proteasome activity.
Volume: 463
Issue: 4
Pages: 1210-7
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Publication
23498975 | J:222672
First Author: Bartolome F
Year: 2013
Journal: Neuron
Title: Pathogenic VCP mutations induce mitochondrial uncoupling and reduced ATP levels.
Volume: 78
Issue: 1
Pages: 57-64
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Publication
18468455 | J:136981
First Author: Wilbrey AL
Year: 2008
Journal: Mol Cell Neurosci
Title: VCP binding influences intracellular distribution of the slow Wallerian degeneration protein, Wld(S).
Volume: 38
Issue: 3
Pages: 325-40
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Publication
26984393 | J:236751
 
First Author: Shih YT
Year: 2016
Journal: Nat Commun
Title: VCP and ATL1 regulate endoplasmic reticulum and protein synthesis for dendritic spine formation.
Volume: 7
Pages: 11020
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Publication
30654731 | J:295049
First Author: Arhzaouy K
Year: 2019
Journal: Autophagy
Title: VCP maintains lysosomal homeostasis and TFEB activity in differentiated skeletal muscle.
Volume: 15
Issue: 6
Pages: 1082-1099
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Publication
24130765 | J:215142
First Author: Nalbandian A
Year: 2013
Journal: PLoS One
Title: Exercise training reverses skeletal muscle atrophy in an experimental model of VCP disease.
Volume: 8
Issue: 10
Pages: e76187
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Publication
25388089 | J:277887
First Author: Nalbandian A
Year: 2015
Journal: Clin Transl Sci
Title: Global gene expression profiling in R155H knock-in murine model of VCP disease.
Volume: 8
Issue: 1
Pages: 8-16
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Publication
30100055 | J:272320
First Author: Clemen CS
Year: 2018
Journal: Biochem Biophys Res Commun
Title: The heterozygous R155C VCP mutation: Toxic in humans! Harmless in mice?
Volume: 503
Issue: 4
Pages: 2770-2777
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Publication
27561680 | J:241613
 
First Author: Guo X
Year: 2016
Journal: Nat Commun
Title: VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington's disease.
Volume: 7
Pages: 12646
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Publication
32610136 | J:300703
First Author: Shih YT
Year: 2020
Journal: Cell Rep
Title: Vcp Overexpression and Leucine Supplementation Increase Protein Synthesis and Improve Fear Memory and Social Interaction of Nf1 Mutant Mice.
Volume: 31
Issue: 13
Pages: 107835
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Publication
25545721 | J:232691
First Author: Nalbandian A
Year: 2015
Journal: Hum Gene Ther Methods
Title: Targeted excision of VCP R155H mutation by Cre-LoxP technology as a promising therapeutic strategy for valosin-containing protein disease.
Volume: 26
Issue: 1
Pages: 13-24
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Publication
20957154 | J:166230
 
First Author: Badadani M
Year: 2010
Journal: PLoS One
Title: VCP associated inclusion body myopathy and paget disease of bone knock-in mouse model exhibits tissue pathology typical of human disease.
Volume: 5
Issue: 10
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Gene
84923 | VCF1
Type: gene
Organism: human
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Gene
90736 | VCF2
Type: gene
Organism: human
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Publication
33437936 | J:306919
First Author: Huang TN
Year: 2021
Journal: iScience
Title: Social behaviors and contextual memory of Vcp mutant mice are sensitive to nutrition and can be ameliorated by amino acid supplementation.
Volume: 24
Issue: 1
Pages: 101949
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Publication
26134519 | J:238312
First Author: Llewellyn KJ
Year: 2015
Journal: PLoS One
Title: A Fine Balance of Dietary Lipids Improves Pathology of a Murine Model of VCP-Associated Multisystem Proteinopathy.
Volume: 10
Issue: 7
Pages: e0131995
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Publication
7989749 | J:21897
First Author: Schulte RJ
Year: 1994
Journal: J Immunol
Title: Tyrosine phosphorylation of VCP, the mammalian homologue of the Saccharomyces cerevisiae CDC48 protein, is unusually sensitive to stimulation by sodium vanadate and hydrogen peroxide.
Volume: 153
Issue: 12
Pages: 5465-72
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Publication
20410307 | J:165369
First Author: Koike M
Year: 2010
Journal: J Biol Chem
Title: Valosin-containing protein (VCP) in novel feedback machinery between abnormal protein accumulation and transcriptional suppression.
Volume: 285
Issue: 28
Pages: 21736-49
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Publication
23091005 | J:191235
First Author: Hauler F
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: AAA ATPase p97/VCP is essential for TRIM21-mediated virus neutralization.
Volume: 109
Issue: 48
Pages: 19733-8
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Publication
12504083 | J:81362
First Author: Kaneko C
Year: 2003
Journal: Biochem Biophys Res Commun
Title: Characterization of the mouse gene for the U-box-type ubiquitin ligase UFD2a.
Volume: 300
Issue: 2
Pages: 297-304
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Publication
1382975 | J:2369
First Author: Egerton M
Year: 1992
Journal: EMBO J
Title: VCP, the mammalian homolog of cdc48, is tyrosine phosphorylated in response to T cell antigen receptor activation.
Volume: 11
Issue: 10
Pages: 3533-40
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Publication
20147319 | J:158713
First Author: Custer SK
Year: 2010
Journal: Hum Mol Genet
Title: Transgenic mice expressing mutant forms VCP/p97 recapitulate the full spectrum of IBMPFD including degeneration in muscle, brain and bone.
Volume: 19
Issue: 9
Pages: 1741-55
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Publication
35430252 | J:325062
First Author: Shibuya K
Year: 2022
Journal: J Biol Chem
Title: AAA-ATPase valosin-containing protein binds the transcription factor SREBP1 and promotes its proteolytic activation by rhomboid protease RHBDL4.
Volume: 298
Issue: 6
Pages: 101936
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Publication
23029473 | J:191963
First Author: Nalbandian A
Year: 2012
Journal: PLoS One
Title: The homozygote VCP(R¹⁵⁵H/R¹⁵⁵H) mouse model exhibits accelerated human VCP-associated disease pathology.
Volume: 7
Issue: 9
Pages: e46308
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Publication
22898872 | J:278297
 
First Author: Yin HZ
Year: 2012
Journal: Cell Death Dis
Title: Slow development of ALS-like spinal cord pathology in mutant valosin-containing protein gene knock-in mice.
Volume: 3
Pages: e374
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Publication
27106764 | J:233684
First Author: Rodriguez-Ortiz CJ
Year: 2016
Journal: Am J Pathol
Title: The Myoblast C2C12 Transfected with Mutant Valosin-Containing Protein Exhibits Delayed Stress Granule Resolution on Oxidative Stress.
Volume: 186
Issue: 6
Pages: 1623-34
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Publication
24158850 | J:206220
First Author: Llewellyn KJ
Year: 2014
Journal: Hum Mol Genet
Title: Lipid-enriched diet rescues lethality and slows down progression in a murine model of VCP-associated disease.
Volume: 23
Issue: 5
Pages: 1333-44
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Publication
11483959 | J:159080
First Author: Dai RM
Year: 2001
Journal: Nat Cell Biol
Title: Valosin-containing protein is a multi-ubiquitin chain-targeting factor required in ubiquitin-proteasome degradation.
Volume: 3
Issue: 8
Pages: 740-4
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Publication
16371511 | J:111720
First Author: Laser H
Year: 2006
Journal: Mol Biol Cell
Title: The slow Wallerian degeneration protein, WldS, binds directly to VCP/p97 and partially redistributes it within the nucleus.
Volume: 17
Issue: 3
Pages: 1075-84
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Publication
28799247 | J:245118
First Author: Zhou N
Year: 2017
Journal: Aging Cell
Title: The valosin-containing protein is a novel repressor of cardiomyocyte hypertrophy induced by pressure overload.
Volume: 16
Issue: 5
Pages: 1168-1179
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Publication
28425440 | J:275271
 
First Author: Lizano P
Year: 2017
Journal: Sci Rep
Title: The valosin-containing protein is a novel mediator of mitochondrial respiration and cell survival in the heart in vivo.
Volume: 7
Pages: 46324
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Publication
30476006 | J:277638
First Author: Peng H
Year: 2019
Journal: Biol Reprod
Title: Valosin-containing protein is associated with maintenance of meiotic arrest in mouse oocytes†.
Volume: 100
Issue: 4
Pages: 963-970
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Publication
30979586 | J:275687
First Author: Wang B
Year: 2019
Journal: Mol Cell
Title: ULK1 and ULK2 Regulate Stress Granule Disassembly Through Phosphorylation and Activation of VCP/p97.
Volume: 74
Issue: 4
Pages: 742-757.e8
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Publication
26544960 | J:244368
First Author: Fusser M
Year: 2015
Journal: PLoS One
Title: Lysine Methylation of the Valosin-Containing Protein (VCP) Is Dispensable for Development and Survival of Mice.
Volume: 10
Issue: 11
Pages: e0141472
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Publication
25884947 | J:233484
First Author: Nalbandian A
Year: 2015
Journal: PLoS One
Title: Rapamycin and chloroquine: the in vitro and in vivo effects of autophagy-modifying drugs show promising results in valosin containing protein multisystem proteinopathy.
Volume: 10
Issue: 4
Pages: e0122888
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Publication
33931547 | J:339548
First Author: Leinonen H
Year: 2021
Journal: J Pharmacol Exp Ther
Title: A p97/Valosin-Containing Protein Inhibitor Drug CB-5083 Has a Potent but Reversible Off-Target Effect on Phosphodiesterase-6.
Volume: 378
Issue: 1
Pages: 31-41
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Publication
22105171 | J:184421
First Author: Wang HF
Year: 2011
Journal: J Clin Invest
Title: Valosin-containing protein and neurofibromin interact to regulate dendritic spine density.
Volume: 121
Issue: 12
Pages: 4820-37
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Publication
38685170 | J:352044
 
First Author: Shi X
Year: 2024
Journal: Redox Biol
Title: Valosin-containing protein acts as a target and mediator of S-nitrosylation in the heart through distinct mechanisms.
Volume: 72
Pages: 103166
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Publication
16525503 | J:145209
First Author: Boeddrich A
Year: 2006
Journal: EMBO J
Title: An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis.
Volume: 25
Issue: 7
Pages: 1547-58
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Publication
23250913 | J:193290
First Author: Ching JK
Year: 2013
Journal: Hum Mol Genet
Title: mTOR dysfunction contributes to vacuolar pathology and weakness in valosin-containing protein associated inclusion body myopathy.
Volume: 22
Issue: 6
Pages: 1167-79
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Publication
23018179 | J:193567
First Author: Abaan OD
Year: 2013
Journal: Exp Cell Res
Title: Valosin containing protein (VCP/p97) is a novel substrate for the protein tyrosine phosphatase PTPL1.
Volume: 319
Issue: 1
Pages: 1-11
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Publication
23737493 | J:218650
First Author: Lizano P
Year: 2013
Journal: Cardiovasc Res
Title: The valosin-containing protein promotes cardiac survival through the inducible isoform of nitric oxide synthase.
Volume: 99
Issue: 4
Pages: 685-93
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Publication
27730320 | J:315426
First Author: Nalbandian A
Year: 2017
Journal: Inflammation
Title: Activation of the NLRP3 Inflammasome Is Associated with Valosin-Containing Protein Myopathy.
Volume: 40
Issue: 1
Pages: 21-41
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Publication
30504720 | J:323341
First Author: Jia CC
Year: 2018
Journal: Cell Physiol Biochem
Title: B-Cell Receptor-Associated Protein 31 Regulates the Expression of Valosin-Containing Protein Through Elf2.
Volume: 51
Issue: 4
Pages: 1799-1814
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Publication
34130995 | J:308471
 
First Author: Homma H
Year: 2021
Journal: Life Sci Alliance
Title: DNA damage in embryonic neural stem cell determines FTLDs' fate via early-stage neuronal necrosis.
Volume: 4
Issue: 7
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Publication
20018231 | J:159744
First Author: Beirowski B
Year: 2010
Journal: Neuroscience
Title: WldS can delay Wallerian degeneration in mice when interaction with valosin-containing protein is weakened.
Volume: 166
Issue: 1
Pages: 201-11
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Publication
36300783 | J:344874
First Author: Bai Y
Year: 2023
Journal: Autophagy
Title: PTP4A2 promotes lysophagy by dephosphorylation of VCP/p97 at Tyr805.
Volume: 19
Issue: 5
Pages: 1562-1581
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Protein Coding Gene
MGP_CAROLIEiJ_G0025925 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0028196 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0028152 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0028104 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0028172 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0027894 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_99919 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0028613 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0027334 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0028009 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0027976 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0028108 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0028000 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0028649 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0027060 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0027414 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0024070 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0026886 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
15740751 | J:240290
First Author: DeLaBarre B
Year: 2005
Journal: J Mol Biol
Title: Nucleotide dependent motion and mechanism of action of p97/VCP.
Volume: 347
Issue: 2
Pages: 437-52
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Publication
11740563 | J:73327
First Author: Ye Y
Year: 2001
Journal: Nature
Title: The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol.
Volume: 414
Issue: 6864
Pages: 652-6
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Publication
27753622 | J:240049
First Author: Papadopoulos C
Year: 2017
Journal: EMBO J
Title: VCP/p97 cooperates with YOD1, UBXD1 and PLAA to drive clearance of ruptured lysosomes by autophagy.
Volume: 36
Issue: 2
Pages: 135-150
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Publication
36746962 | J:336268
First Author: Ganji R
Year: 2023
Journal: Nat Commun
Title: The p97-UBXD8 complex regulates ER-Mitochondria contact sites by altering membrane lipid saturation and composition.
Volume: 14
Issue: 1
Pages: 638
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Publication
17239345 | J:118184
First Author: Müller JM
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Targeted deletion of p97 (VCP/CDC48) in mouse results in early embryonic lethality.
Volume: 354
Issue: 2
Pages: 459-65
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Publication
31973812 | J:298865
First Author: Cheng C
Year: 2020
Journal: Biochem Biophys Res Commun
Title: Expression level of R155H mRNA in the knock-in mouse model.
Volume: 523
Issue: 4
Pages: 985-986
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Publication
23169451 | J:278263
First Author: Nalbandian A
Year: 2013
Journal: Muscle Nerve
Title: A progressive translational mouse model of human valosin-containing protein disease: the VCP(R155H/+) mouse.
Volume: 47
Issue: 2
Pages: 260-70
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Publication
20691684 | J:201304
First Author: Kaneko Y
Year: 2010
Journal: FEBS Lett
Title: Isolation of a point-mutated p47 lacking binding affinity to p97ATPase.
Volume: 584
Issue: 18
Pages: 3873-7
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Publication
24424410 | J:221547
 
First Author: Liu Y
Year: 2014
Journal: Elife
Title: USP13 antagonizes gp78 to maintain functionality of a chaperone in ER-associated degradation.
Volume: 3
Pages: e01369
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Publication
18462676 | J:247402
First Author: Davies JM
Year: 2008
Journal: Structure
Title: Improved structures of full-length p97, an AAA ATPase: implications for mechanisms of nucleotide-dependent conformational change.
Volume: 16
Issue: 5
Pages: 715-26
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Publication
10187799 | J:54314
First Author: Müller JM
Year: 1999
Journal: J Biol Chem
Title: The mouse p97 (CDC48) gene. Genomic structure, definition of transcriptional regulatory sequences, gene expression, and characterization of a pseudogene.
Volume: 274
Issue: 15
Pages: 10154-62
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Publication
16321991 | J:104453
First Author: Weihl CC
Year: 2006
Journal: Hum Mol Genet
Title: Inclusion body myopathy-associated mutations in p97/VCP impair endoplasmic reticulum-associated degradation.
Volume: 15
Issue: 2
Pages: 189-99
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Publication
16713576 | J:111297
First Author: DeLaBarre B
Year: 2006
Journal: Mol Cell
Title: Central pore residues mediate the p97/VCP activity required for ERAD.
Volume: 22
Issue: 4
Pages: 451-62
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Publication
17329348 | J:121709
First Author: Weihl CC
Year: 2007
Journal: Hum Mol Genet
Title: Transgenic expression of inclusion body myopathy associated mutant p97/VCP causes weakness and ubiquitinated protein inclusions in mice.
Volume: 16
Issue: 8
Pages: 919-28
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Publication
18706391 | J:138983
First Author: Li G
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Tyrosine phosphorylation of ATPase p97 regulates its activity during ERAD.
Volume: 375
Issue: 2
Pages: 247-51
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