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Search results 501 to 543 out of 543 for Stam

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Type Details Score
Publication
26101075 | J:226940
 
First Author: Kapuralin K
Year: 2015
Journal: Mol Cell Neurosci
Title: STAM2, a member of the endosome-associated complex ESCRT-0 is highly expressed in neurons.
Volume: 67
Pages: 104-15
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Protein Domain
IPR035657 | STAM1_SH3
Type: Domain
Description: This entry represents the SH3 domain of STAM1 (signal transducing adapter molecule 1). STAM1 is part of the endosomal sorting complex required for transport (ESCRT-0) and is involved in sorting ubiquitinated cargo proteins from the endosome []. It may also be involved in the regulation of IL2 and GM-CSF mediated signaling, and has been implicated in neural cell survival [, ]. STAMs were discovered as proteins that are highly phosphorylated following cytokine and growth factor stimulation []. They function in cytokine signaling and surface receptor degradation, as well as regulate Golgi morphology. They associate with many proteins including Jak2 and Jak3 tyrosine kinases [], Hrs, AMSH, and UBPY. STAM adaptor proteins contain VHS (Vps27, Hrs, STAM homology), ubiquitin interacting (UIM), and SH3 domains [].
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Protein Domain
IPR035675 | STAM2_SH3
Type: Domain
Description: This entry represents the SH3 domain of STAM2 (signal transducing adapter molecule 2). STAM2, a subunit of the ESCRT-0 complex, is an endosomal protein acting as a regulator of receptor signaling and trafficking. It contains an N-terminal VHS domain (Vps-27/Hrs/Stam), UIM (ubiquitin-interacting motif), SH3 (Src homology 3), CC ("coiled coil"), SSM (STAM-specific motif) and C-terminal ITAM (immunoreceptor tyrosine-based activation motif) domain. It may play a regulatory role in the endosomal sorting of ubiquitinated membrane proteins []. STAMs were discovered as proteins that are highly phosphorylated following cytokine and growth factor stimulation []. They function in cytokine signaling and surface receptor degradation, as well as regulate Golgi morphology. They associate with many proteins including Jak2 and Jak3 tyrosine kinases [], Hrs, AMSH, and UBPY. STAM adaptor proteins contain VHS (Vps27, Hrs, STAM homology), ubiquitin interacting (UIM), and SH3 domains [].
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Publication
11728436 | -
First Author: Lohi O
Year: 2001
Journal: FEBS Lett
Title: STAM/EAST/Hbp adapter proteins--integrators of signalling pathways.
Volume: 508
Issue: 3
Pages: 287-90
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Publication
12176364 | J:230362
First Author: Berry DM
Year: 2002
Journal: Curr Biol
Title: A high-affinity Arg-X-X-Lys SH3 binding motif confers specificity for the interaction between Gads and SLP-76 in T cell signaling.
Volume: 12
Issue: 15
Pages: 1336-41
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Publication
19278655 | J:245341
First Author: Ren X
Year: 2009
Journal: Structure
Title: Hybrid structural model of the complete human ESCRT-0 complex.
Volume: 17
Issue: 3
Pages: 406-16
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Publication
27134167 | J:235481
First Author: Lau EY
Year: 2016
Journal: Cell Rep
Title: Cancer-Associated Fibroblasts Regulate Tumor-Initiating Cell Plasticity in Hepatocellular Carcinoma through c-Met/FRA1/HEY1 Signaling.
Volume: 15
Issue: 6
Pages: 1175-89
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Publication
37852976 | J:341628
First Author: Soeda K
Year: 2023
Journal: Nat Commun
Title: Gut insulin action protects from hepatocarcinogenesis in diabetic mice comorbid with nonalcoholic steatohepatitis.
Volume: 14
Issue: 1
Pages: 6584
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HT Experiment
E-GEOD-83596 | Hepatic transcriptomic changes during non-alcoholic steatohepatitis (NASH)-associated liver carcinogenesis in mice
Series Id: GSE83596
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
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Publication
16458478 | J:114923
First Author: Chan WY
Year: 2006
Journal: Genomics
Title: The complexity of antisense transcription revealed by the study of developing male germ cells.
Volume: 87
Issue: 6
Pages: 681-92
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Publication
10329004 | J:54916
First Author: Seroussi E
Year: 1999
Journal: Genomics
Title: TOM1 genes map to human chromosome 22q13.1 and mouse chromosome 8C1 and encode proteins similar to the endosomal proteins HGS and STAM.
Volume: 57
Issue: 3
Pages: 380-8
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Publication
15774496 | J:99850
First Author: Li LV
Year: 2005
Journal: Mol Endocrinol
Title: Golgi-localized, gamma-ear-containing, Arf-binding protein adaptors mediate insulin-responsive trafficking of glucose transporter 4 in 3T3-L1 adipocytes.
Volume: 19
Issue: 8
Pages: 2145-53
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Publication
36531991 | J:332254
 
First Author: Li T
Year: 2022
Journal: Front Immunol
Title: Akkermansia muciniphila suppressing nonalcoholic steatohepatitis associated tumorigenesis through CXCR6(+) natural killer T cells.
Volume: 13
Pages: 1047570
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Publication
25607821 | J:305895
First Author: Yoshimine Y
Year: 2015
Journal: Oncol Rep
Title: Hepatic expression of the Sptlc3 subunit of serine palmitoyltransferase is associated with the development of hepatocellular carcinoma in a mouse model of nonalcoholic steatohepatitis.
Volume: 33
Issue: 4
Pages: 1657-66
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Publication
24983359 | J:218942
First Author: Ishikawa H
Year: 2014
Journal: PLoS One
Title: L-carnitine prevents progression of non-alcoholic steatohepatitis in a mouse model with upregulation of mitochondrial pathway.
Volume: 9
Issue: 7
Pages: e100627
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Protein Coding Gene
MGI:104681 | Hgs
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
O88811
Organism: Mus musculus/domesticus
Length: 523  
Fragment?: false
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Protein
P70297
Organism: Mus musculus/domesticus
Length: 548  
Fragment?: false
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Protein
Q3TQ49
Organism: Mus musculus/domesticus
Length: 548  
Fragment?: false
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Protein
Q3UGN9
Organism: Mus musculus/domesticus
Length: 462  
Fragment?: false
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Protein
Q3UMC8
Organism: Mus musculus/domesticus
Length: 553  
Fragment?: false
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Protein
Q3TGH8
Organism: Mus musculus/domesticus
Length: 523  
Fragment?: false
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:68100
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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