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Search results 1 to 100 out of 641 for Cbl

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Type Details Score
Gene
867 | CBL
Type: gene
Organism: human
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Gene
704311 | CBL
Type: gene
Organism: macaque, rhesus
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Gene
492364 | cbl
Type: gene
Organism: zebrafish
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Gene
594900 | cbl
Type: gene
Organism: frog, western clawed
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Gene
500985 | Cbl
Type: gene
Organism: rat
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Gene
489369 | CBL
Type: gene
Organism: dog, domestic
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Gene
374038 | CBL
Type: gene
Organism: chicken
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Gene
451690 | CBL
Type: gene
Organism: chimpanzee
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Gene
527418 | CBL
Type: gene
Organism: cattle
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Protein Coding Gene
MGI:88279 | Cbl
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
10393178 | J:56338
First Author: Lee PS
Year: 1999
Journal: EMBO J
Title: The Cbl protooncoprotein stimulates CSF-1 receptor multiubiquitination and endocytosis, and attenuates macrophage proliferation.
Volume: 18
Issue: 13
Pages: 3616-28
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Publication
9653117 | J:48737
First Author: Miyake S
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: The tyrosine kinase regulator Cbl enhances the ubiquitination and degradation of the platelet-derived growth factor receptor alpha.
Volume: 95
Issue: 14
Pages: 7927-32
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Gene
868 | CBLB
Type: gene
Organism: human
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Gene
23624 | CBLC
Type: gene
Organism: human
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Gene
79872 | CBLL1
Type: gene
Organism: human
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Gene
158506 | CBLL2
Type: gene
Organism: human
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Publication
8770364 | J:36118
First Author: Langdon WY
Year: 1995
Journal: Aust N Z J Med
Title: The cbl oncogene: a novel substrate of protein tyrosine kinases.
Volume: 25
Issue: 6
Pages: 859-64
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Publication
29237719 | J:281256
First Author: Schmid FM
Year: 2018
Journal: J Cell Biol
Title: IFT20 modulates ciliary PDGFRα signaling by regulating the stability of Cbl E3 ubiquitin ligases.
Volume: 217
Issue: 1
Pages: 151-161
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Publication
19074136 | J:147595
First Author: Chiang YJ
Year: 2009
Journal: J Biol Chem
Title: Cbl enforces an SLP76-dependent signaling pathway for T cell differentiation.
Volume: 284
Issue: 7
Pages: 4429-38
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Publication
24113870 | J:328418
First Author: Bulut GB
Year: 2013
Journal: Blood
Title: Cbl ubiquitination of p85 is essential for Epo-induced EpoR endocytosis.
Volume: 122
Issue: 24
Pages: 3964-72
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Publication
12671687 | J:115703
First Author: Shao Y
Year: 2003
Journal: EMBO Rep
Title: Negative regulation of Rap1 activation by the Cbl E3 ubiquitin ligase.
Volume: 4
Issue: 4
Pages: 425-31
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Publication
21490975 | J:172283
First Author: Chiang J
Year: 2011
Journal: PLoS One
Title: Cbl enforces Vav1 dependence and a restricted pathway of T cell development.
Volume: 6
Issue: 4
Pages: e18542
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Publication
2030914 | J:37010
First Author: Blake TJ
Year: 1991
Journal: Oncogene
Title: The sequences of the human and mouse c-cbl proto-oncogenes show v-cbl was generated by a large truncation encompassing a proline-rich domain and a leucine zipper-like motif.
Volume: 6
Issue: 4
Pages: 653-7
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Publication
29562201 | J:272419
First Author: Li X
Year: 2018
Journal: Immunity
Title: Cbl Ubiquitin Ligases Control B Cell Exit from the Germinal-Center Reaction.
Volume: 48
Issue: 3
Pages: 530-541.e6
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Publication
17493844 | J:123596
First Author: Kitaura Y
Year: 2007
Journal: Immunity
Title: Control of the B cell-intrinsic tolerance programs by ubiquitin ligases Cbl and Cbl-b.
Volume: 26
Issue: 5
Pages: 567-78
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Publication
16494846 | J:106781
First Author: Gupte A
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Activation of the Cbl insulin signaling pathway in cardiac muscle; dysregulation in obesity and diabetes.
Volume: 342
Issue: 3
Pages: 751-7
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Publication
32584413 | J:305085
 
First Author: Li X
Year: 2020
Journal: J Exp Med
Title: Cbl and Cbl-b control the germinal center reaction by facilitating naive B cell antigen processing.
Volume: 217
Issue: 9
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GXD Expression
GXD Expression
   
Probe: MGI:2667164
Assay Type: RNase protection
Annotation Date: 2003-07-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:2667202
Age: postnatal adult
Image: 2
Specimen Label: cbl
Detected: true
Specimen Num: 16
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GXD Expression
GXD Expression
     
Probe: MGI:3772057
Assay Type: RT-PCR
Annotation Date: 2008-02-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:3772063
Age: postnatal month 2
Specimen Label: Cbl
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:5473546
Assay Type: Western blot
Annotation Date: 2013-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778727
Stage: TS27
Assay Id: MGI:5473557
Age: postnatal day 0
Image: 2
Specimen Label: cbl
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5473546
Assay Type: Western blot
Annotation Date: 2013-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:5473558
Age: postnatal adult
Image: 2
Specimen Label: cbl
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6864066
Assay Type: Western blot
Annotation Date: 2022-02-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:6864079
Age: postnatal adult
Image: 2
Specimen Label: cbl
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
   
Probe: MGI:7520263
Assay Type: Northern blot
Annotation Date: 2023-08-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:7520334
Age: postnatal adult
Image: 3
Specimen Label: CBL
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:7571378
Assay Type: RT-PCR
Annotation Date: 2024-01-04
Strength: Present
Sex: Male
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:7571385
Age: postnatal adult
Image: 3
Specimen Label: Cbl
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7571379
Assay Type: RT-PCR
Annotation Date: 2024-01-04
Strength: Present
Sex: Male
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:7571386
Age: postnatal adult
Image: 3
Specimen Label: Cbl
Detected: true
Specimen Num: 2
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Publication
12652654 | J:82782
First Author: Caveggion E
Year: 2003
Journal: J Cell Physiol
Title: Expression and tyrosine phosphorylation of Cbl regulates macrophage chemokinetic and chemotactic movement.
Volume: 195
Issue: 2
Pages: 276-89
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Publication
28100467 | J:245033
First Author: Mohapatra B
Year: 2017
Journal: Development
Title: An essential role of CBL and CBL-B ubiquitin ligases in mammary stem cell maintenance.
Volume: 144
Issue: 6
Pages: 1072-1086
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Publication
8798454 | J:35411
First Author: Latour S
Year: 1996
Journal: J Biol Chem
Title: Differential intrinsic enzymatic activity of Syk and Zap-70 protein-tyrosine kinases.
Volume: 271
Issue: 37
Pages: 22782-90
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Publication
8551236 | J:35635
First Author: Fournel M
Year: 1996
Journal: J Exp Med
Title: Association of tyrosine protein kinase Zap-70 with the protooncogene product p120c-cbl in T lymphocytes.
Volume: 183
Issue: 1
Pages: 301-6
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Publication
34630435 | J:312696
 
First Author: Tong H
Year: 2021
Journal: Front Immunol
Title: Ubiquitin Ligases CBL and CBL-B Maintain the Homeostasis and Immune Quiescence of Dendritic Cells.
Volume: 12
Pages: 757231
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Publication
27449297 | J:302686
First Author: An W
Year: 2016
Journal: Oncotarget
Title: VAV1-Cre mediated hematopoietic deletion of CBL and CBL-B leads to JMML-like aggressive early-neonatal myeloproliferative disease.
Volume: 7
Issue: 37
Pages: 59006-59016
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Publication
38019655 | J:347517
First Author: Henry CM
Year: 2023
Journal: Cell Rep
Title: SYK ubiquitination by CBL E3 ligases restrains cross-presentation of dead cell-associated antigens by type 1 dendritic cells.
Volume: 42
Issue: 12
Pages: 113506
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Publication
25871390 | J:302741
First Author: An W
Year: 2015
Journal: Oncotarget
Title: Loss of Cbl and Cbl-b ubiquitin ligases abrogates hematopoietic stem cell quiescence and sensitizes leukemic disease to chemotherapy.
Volume: 6
Issue: 12
Pages: 10498-509
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Publication
9890970 | J:200344
First Author: Hunter S
Year: 1999
Journal: J Biol Chem
Title: Fyn associates with Cbl and phosphorylates tyrosine 731 in Cbl, a binding site for phosphatidylinositol 3-kinase.
Volume: 274
Issue: 4
Pages: 2097-106
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Protein
B1NE43
Organism: Mus musculus/domesticus
Length: 83  
Fragment?: true
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Publication
17045823 | J:114877
First Author: Huang F
Year: 2006
Journal: Immunity
Title: Establishment of the major compatibility complex-dependent development of CD4+ and CD8+ T cells by the Cbl family proteins.
Volume: 25
Issue: 4
Pages: 571-81
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Publication
28611190 | J:243931
First Author: Lv K
Year: 2017
Journal: Genes Dev
Title: CBL family E3 ubiquitin ligases control JAK2 ubiquitination and stability in hematopoietic stem cells and myeloid malignancies.
Volume: 31
Issue: 10
Pages: 1007-1023
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Publication
23457600 | J:199397
First Author: Wang L
Year: 2013
Journal: PLoS One
Title: Berberine inhibits proliferation and down-regulates epidermal growth factor receptor through activation of Cbl in colon tumor cells.
Volume: 8
Issue: 2
Pages: e56666
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Publication
9687507 | J:114192
First Author: Meng F
Year: 1998
Journal: EMBO J
Title: A beta 1 integrin signaling pathway involving Src-family kinases, Cbl and PI-3 kinase is required for macrophage spreading and migration.
Volume: 17
Issue: 15
Pages: 4391-403
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Publication
21703542 | J:173993
First Author: Schnyder T
Year: 2011
Journal: Immunity
Title: B cell receptor-mediated antigen gathering requires ubiquitin ligase Cbl and adaptors Grb2 and Dok-3 to recruit dynein to the signaling microcluster.
Volume: 34
Issue: 6
Pages: 905-18
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Publication
19380812 | J:147711
First Author: Dale BM
Year: 2009
Journal: J Immunol
Title: Phagocytosis in macrophages lacking Cbl reveals an unsuspected role for Fc gamma receptor signaling and actin assembly in target binding.
Volume: 182
Issue: 9
Pages: 5654-62
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Publication
27474268 | J:239186
First Author: Voisinne G
Year: 2016
Journal: Mol Syst Biol
Title: Co-recruitment analysis of the CBL and CBLB signalosomes in primary T cells identifies CD5 as a key regulator of TCR-induced ubiquitylation.
Volume: 12
Issue: 7
Pages: 876
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Publication
38761804 | J:354878
First Author: Li X
Year: 2024
Journal: Immunity
Title: Deficiency of CBL and CBLB ubiquitin ligases leads to hyper T follicular helper cell responses and lupus by reducing BCL6 degradation.
Volume: 57
Issue: 7
Pages: 1603-1617.e7
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Publication
8627181 | J:305755
First Author: Tezuka T
Year: 1996
Journal: J Exp Med
Title: Physical and functional association of the cbl protooncogen product with an src-family protein tyrosine kinase, p53/56lyn, in the B cell antigen receptor-mediated signaling.
Volume: 183
Issue: 2
Pages: 675-80
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Protein
P22682
Organism: Mus musculus/domesticus
Length: 913  
Fragment?: false
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Publication
18034775 | J:177152
First Author: Fasen K
Year: 2008
Journal: Traffic
Title: Ligand binding induces Cbl-dependent EphB1 receptor degradation through the lysosomal pathway.
Volume: 9
Issue: 2
Pages: 251-66
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Publication
12024036 | J:76785
First Author: Loreto MP
Year: 2002
Journal: Mol Cell Biol
Title: Functional cooperation between c-Cbl and Src-like adaptor protein 2 in the negative regulation of T-cell receptor signaling.
Volume: 22
Issue: 12
Pages: 4241-55
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Publication
9824625 | -
First Author: Ollendorff V
Year: 1998
Journal: Int J Oncol
Title: A third human CBL gene is on chromosome 19.
Volume: 13
Issue: 6
Pages: 1159-61
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Protein
A0A0U1RP95
Organism: Mus musculus/domesticus
Length: 79  
Fragment?: true
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Protein
B1NE42
Organism: Mus musculus/domesticus
Length: 78  
Fragment?: true
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Publication
26393915 | J:227226
First Author: Scanlon V
Year: 2015
Journal: PLoS One
Title: Role of Cbl-PI3K Interaction during Skeletal Remodeling in a Murine Model of Bone Repair.
Volume: 10
Issue: 9
Pages: e0138194
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Publication
31299383 | J:294733
 
First Author: Yu J
Year: 2019
Journal: Bone
Title: Cbl-PI3K interaction regulates Cathepsin K secretion in osteoclasts.
Volume: 127
Pages: 376-385
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Publication
28209720 | J:241533
First Author: Nakata Y
Year: 2017
Journal: Blood
Title: Acquired expression of CblQ367P in mice induces dysplastic myelopoiesis mimicking chronic myelomonocytic leukemia.
Volume: 129
Issue: 15
Pages: 2148-2160
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Publication
20851882 | J:167020
First Author: Adapala NS
Year: 2010
Journal: J Biol Chem
Title: The loss of Cbl-phosphatidylinositol 3-kinase interaction perturbs RANKL-mediated signaling, inhibiting bone resorption and promoting osteoclast survival.
Volume: 285
Issue: 47
Pages: 36745-58
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Publication
31665177 | J:281600
First Author: Doherty L
Year: 2019
Journal: PLoS One
Title: A PDGFRβ-PI3K signaling axis mediates periosteal cell activation during fracture healing.
Volume: 14
Issue: 10
Pages: e0223846
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Publication
24994594 | J:215452
 
First Author: Adapala NS
Year: 2014
Journal: Bone
Title: Loss of Cbl-PI3K interaction in mice prevents significant bone loss following ovariectomy.
Volume: 67
Pages: 1-9
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Publication
21830225 | J:227464
First Author: Feng L
Year: 2011
Journal: Cell Biochem Funct
Title: SH3KBP1-binding protein 1 prevents epidermal growth factor receptor degradation by the interruption of c-Cbl-CIN85 complex.
Volume: 29
Issue: 7
Pages: 589-96
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Publication
27884787 | J:255148
 
First Author: Scanlon V
Year: 2017
Journal: Bone
Title: Loss of Cbl-PI3K interaction modulates the periosteal response to fracture by enhancing osteogenic commitment and differentiation.
Volume: 95
Pages: 124-135
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Protein
A0A0U1RP17
Organism: Mus musculus/domesticus
Length: 51  
Fragment?: true
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Publication
9447983 | J:46223
First Author: Ribon V
Year: 1998
Journal: Mol Cell Biol
Title: A novel, multifuntional c-Cbl binding protein in insulin receptor signaling in 3T3-L1 adipocytes.
Volume: 18
Issue: 2
Pages: 872-9
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Publication
23374343 | J:193456
First Author: Chen W
Year: 2013
Journal: Cell
Title: Induction of Siglec-G by RNA viruses inhibits the innate immune response by promoting RIG-I degradation.
Volume: 152
Issue: 3
Pages: 467-78
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Publication
24470255 | J:244051
First Author: Adapala NS
Year: 2014
Journal: J Cell Biochem
Title: Loss of Cbl-PI3K interaction enhances osteoclast survival due to p21-Ras mediated PI3K activation independent of Cbl-b.
Volume: 115
Issue: 7
Pages: 1277-89
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Publication
32954656 | J:329627
First Author: Märklin M
Year: 2020
Journal: J Cell Mol Med
Title: C-Cbl regulates c-MPL receptor trafficking and its internalization.
Volume: 24
Issue: 21
Pages: 12491-12503
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Publication
17130487 | J:121012
First Author: Molero JC
Year: 2006
Journal: Diabetes
Title: Genetic ablation of the c-Cbl ubiquitin ligase domain results in increased energy expenditure and improved insulin action.
Volume: 55
Issue: 12
Pages: 3411-7
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Publication
21967979 | J:178858
First Author: Buitrago L
Year: 2011
Journal: Blood
Title: Tyrosine phosphorylated c-Cbl regulates platelet functional responses mediated by outside-in signaling.
Volume: 118
Issue: 20
Pages: 5631-40
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Publication
20133944 | J:161184
First Author: Thien CB
Year: 2010
Journal: J Biol Chem
Title: c-Cbl promotes T cell receptor-induced thymocyte apoptosis by activating the phosphatidylinositol 3-kinase/Akt pathway.
Volume: 285
Issue: 14
Pages: 10969-81
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Publication
15304502 | J:119327
First Author: Shao Y
Year: 2004
Journal: J Biol Chem
Title: Differential regulation of the B cell receptor-mediated signaling by the E3 ubiquitin ligase Cbl.
Volume: 279
Issue: 42
Pages: 43646-53
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Publication
12415267 | J:80427
First Author: Naramura M
Year: 2002
Journal: Nat Immunol
Title: c-Cbl and Cbl-b regulate T cell responsiveness by promoting ligand-induced TCR down-modulation.
Volume: 3
Issue: 12
Pages: 1192-9
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Publication
24440350 | J:206833
First Author: Leiser D
Year: 2014
Journal: FEBS Lett
Title: Targeting of the MET receptor tyrosine kinase by small molecule inhibitors leads to MET accumulation by impairing the receptor downregulation.
Volume: 588
Issue: 5
Pages: 653-8
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Publication
12591907 | J:81965
First Author: Thien CB
Year: 2003
Journal: J Exp Med
Title: A mouse with a loss-of-function mutation in the c-Cbl TKB domain shows perturbed thymocyte signaling without enhancing the activity of the ZAP-70 tyrosine kinase.
Volume: 197
Issue: 4
Pages: 503-13
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Publication
16301331 | J:104535
First Author: El Chami N
Year: 2005
Journal: J Cell Biol
Title: Androgen-dependent apoptosis in male germ cells is regulated through the proto-oncoprotein Cbl.
Volume: 171
Issue: 4
Pages: 651-61
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Publication
12754251 | J:335499
First Author: Duan L
Year: 2003
Journal: J Biol Chem
Title: Cbl-mediated ubiquitinylation is required for lysosomal sorting of epidermal growth factor receptor but is dispensable for endocytosis.
Volume: 278
Issue: 31
Pages: 28950-60
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Publication
23127761 | J:214050
First Author: Polzer H
Year: 2013
Journal: Exp Hematol
Title: Casitas B-lineage lymphoma mutants activate AKT to induce transformation in cooperation with class III receptor tyrosine kinases.
Volume: 41
Issue: 3
Pages: 271-80.e4
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Publication
9103201 | J:39570
First Author: Ota Y
Year: 1997
Journal: Science
Title: The product of the proto-oncogene c-cbl: a negative regulator of the Syk tyrosine kinase.
Volume: 276
Issue: 5311
Pages: 418-20
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Publication
9671496 | J:76895
First Author: Murphy MA
Year: 1998
Journal: Mol Cell Biol
Title: Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient mice.
Volume: 18
Issue: 8
Pages: 4872-82
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Publication
30118682 | J:348413
First Author: Penn BH
Year: 2018
Journal: Mol Cell
Title: An Mtb-Human Protein-Protein Interaction Map Identifies a Switch between Host Antiviral and Antibacterial Responses.
Volume: 71
Issue: 4
Pages: 637-648.e5
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Publication
9861006 | J:51666
First Author: Naramura M
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Altered thymic positive selection and intracellular signals in Cbl-deficient mice.
Volume: 95
Issue: 26
Pages: 15547-52
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Publication
18566322 | J:138720
First Author: Slape C
Year: 2008
Journal: Blood
Title: Leukemic transformation in mice expressing a NUP98-HOXD13 transgene is accompanied by spontaneous mutations in Nras, Kras, and Cbl.
Volume: 112
Issue: 5
Pages: 2017-9
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Publication
20805496 | J:164365
First Author: Naramura M
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Rapidly fatal myeloproliferative disorders in mice with deletion of Casitas B-cell lymphoma (Cbl) and Cbl-b in hematopoietic stem cells.
Volume: 107
Issue: 37
Pages: 16274-9
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Publication
15962011 | J:99577
First Author: Haglund K
Year: 2005
Journal: EMBO Rep
Title: Sprouty2 acts at the Cbl/CIN85 interface to inhibit epidermal growth factor receptor downregulation.
Volume: 6
Issue: 7
Pages: 635-41
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Publication
27276677 | J:264175
First Author: Goetz B
Year: 2016
Journal: Oncotarget
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