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Search results 301 to 383 out of 383 for Mga

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Type Details Score
GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-11-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3670720
Stage: TS20
Assay Id: MGI:6257881
Age: embryonic day 12.5
Image: 4J
Specimen Label: 4J
Detected: false
Specimen Num: 28
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-11-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3779720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6257881
Age: embryonic day 12.5
Image: 4C
Specimen Label: 4C
Detected: true
Specimen Num: 21
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Publication
35422437 | J:324221
 
First Author: Tanaskovic N
Year: 2022
Journal: Life Sci Alliance
Title: Polycomb group ring finger protein 6 suppresses Myc-induced lymphomagenesis.
Volume: 5
Issue: 8
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Publication
17082620 | J:116665
First Author: Yu X
Year: 2006
Journal: J Immunol
Title: Fine mapping of collagen-induced arthritis quantitative trait loci in an advanced intercross line.
Volume: 177
Issue: 10
Pages: 7042-9
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Publication
24378336 | J:206879
First Author: Huang T
Year: 2014
Journal: Dev Biol
Title: BDNF and NT4 play interchangeable roles in gustatory development.
Volume: 386
Issue: 2
Pages: 308-20
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Publication
16325481 | J:102143
First Author: Yoshikawa T
Year: 2006
Journal: Gene Expr Patterns
Title: High-throughput screen for genes predominantly expressed in the ICM of mouse blastocysts by whole mount in situ hybridization.
Volume: 6
Issue: 2
Pages: 213-24
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Publication
20439489 | J:163558
First Author: Tarantino C
Year: 2010
Journal: FASEB J
Title: miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic stem cells.
Volume: 24
Issue: 9
Pages: 3255-63
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
19521500 | J:149737
First Author: Sansom SN
Year: 2009
Journal: PLoS Genet
Title: The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis.
Volume: 5
Issue: 6
Pages: e1000511
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Publication
19521566 | J:177549
First Author: Willnow T
Year: 2005
Journal: Organogenesis
Title: The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.
Volume: 2
Issue: 2
Pages: 42-7
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Publication
18554416 | J:139177
First Author: Hoffman BG
Year: 2008
Journal: Genome Biol
Title: Identification of transcripts with enriched expression in the developing and adult pancreas.
Volume: 9
Issue: 6
Pages: R99
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
20412781 | J:140465
First Author: Guo G
Year: 2010
Journal: Dev Cell
Title: Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Volume: 18
Issue: 4
Pages: 675-85
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:72247
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
34236315 | J:308027
   
First Author: Mathsyaraja H
Year: 2021
Journal: Elife
Title: Loss of MGA repression mediated by an atypical polycomb complex promotes tumor progression and invasiveness.
Volume: 10
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DO Term
DOID:0110006 | 3-methylglutaconic aciduria type 4
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Publication
- | J:39039
First Author: Harmon D
Year: 1996
Journal: Mouse Genome
Title: Polymorphism of Pax7 in the wild mouse gene pool
Volume: 94
Issue: 4
Pages: 868-70
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Allele
Mga<em1Smoc> | MGI:7291062
Name: MAX gene associated; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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DO Term
DOID:0050476 | Barth syndrome
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DO Term
DOID:0110002 | 3-methylglutaconic aciduria type 1
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Protein Domain
IPR013199 | HTH_Mga_DNA-bd_dom
Type: Domain
Description: Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. It appears to contain two DNA-binding domains that are required for direct activation of the Mga virulence regulon in vivo []. This entry represents the Mga DNA binding domain, which also appears to be found in other regulatory proteins.
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Protein Domain
IPR037935 | MAX_gene-associated_protein
Type: Family
Description: MAX gene-associated protein (MGA) is a dual-specificity transcription factor, acting as a repressor or an activator and binding to 5'-AATTTCACACCTAGGTGTGAAATT-3'. MGA regulates genes targeted by MYC-MAX, suppressing transcriptional activation by MYC and inhibiting MYC-dependent cell transformation. MGA binds DNA via a T-Box []. MGA is a component of the MLL1 complex [].
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Strain
MGI:6770943 | C57BL/6J-Mga<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Protein Domain
IPR032060 | MGA_dom
Type: Domain
Description: This domain can be found in the MAX gene-associated protein (Mga), which is a dual-specificity transcription factor that contains both a bHLHZip domain and a T-box domain and is able to bind to and regulate transcriptional targets through both E-box sites as well as T-box-binding elements (TBEs) []. MAX gene-associated protein (MGA) is a dual-specificity transcription factor, acting as a repressor or an activator and binding to 5'-AATTTCACACCTAGGTGTGAAATT-3'. MGA regulates genes targeted by MYC-MAX, suppressing transcriptional activation by MYC and inhibiting MYC-dependent cell transformation. MGA binds DNA via a T-Box []. MGA is a component of the MLL1 complex [].
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Protein Domain
IPR013236 | Mga_PRD_dom
Type: Domain
Description: Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions []. This region corresponds to the PRD like region.
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Publication
28304275 | J:258919
   
First Author: Endoh M
Year: 2017
Journal: Elife
Title: PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes.
Volume: 6
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Publication
12150962 | J:77875
First Author: Quezada-Calvillo R
Year: 2002
Journal: Biochem Biophys Res Commun
Title: Partial characterization of murine intestinal maltase-glucoamylase.
Volume: 295
Issue: 2
Pages: 394-400
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Publication
9534973 | J:47100
First Author: Boyle MD
Year: 1998
Journal: J Infect Dis
Title: Role of emm and mrp genes in the virulence of group A streptococcal isolate 64/14 in a mouse model of skin infection.
Volume: 177
Issue: 4
Pages: 991-7
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Publication
14723852 | J:87951
First Author: Hamatani T
Year: 2004
Journal: Dev Cell
Title: Dynamics of global gene expression changes during mouse preimplantation development.
Volume: 6
Issue: 1
Pages: 117-31
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HT Experiment
E-GEOD-3962 | Transcription profiling of polysomal mRNA populations of mouse oocytes and zygotes
Series Id: GSE3962
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
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HT Experiment
GSE149025 | Role of E2F6 in gene expression and DNA methylation during mouse development
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
24144980 | J:206754
First Author: Escamilla-Del-Arenal M
Year: 2013
Journal: Mol Cell Biol
Title: Cdyl, a new partner of the inactive X chromosome and potential reader of H3K27me3 and H3K9me2.
Volume: 33
Issue: 24
Pages: 5005-20
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Publication
34117224 | J:307865
First Author: Dahlet T
Year: 2021
Journal: Nat Commun
Title: E2F6 initiates stable epigenetic silencing of germline genes during embryonic development.
Volume: 12
Issue: 1
Pages: 3582
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Publication
26092847 | J:229431
First Author: Suzuki S
Year: 2015
Journal: Development
Title: CHD1 acts via the Hmgpi pathway to regulate mouse early embryogenesis.
Volume: 142
Issue: 13
Pages: 2375-84
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Publication
11823794 | -
First Author: Trimarchi JM
Year: 2002
Journal: Nat Rev Mol Cell Biol
Title: Sibling rivalry in the E2F family.
Volume: 3
Issue: 1
Pages: 11-20
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Protein Domain
IPR015635 | Transcription_factor_E2F6
Type: Family
Description: E2F6 is a member of the E2F family of transcription factors. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA-binding domain, a dimerisation domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumour suppressor protein association domain which is embedded within the transactivation domain. E2F6 is atypical because it lacks the transactivation and tumour suppressor protein association domains. It contains a modular suppression domain and is an inhibitor of E2F-dependent transcription. The protein is part of a multimeric protein complex that contains a histone methyltransferase and the transcription factors Mga and Max. Multiple transcript variants encoding several different isoforms have been found for this gene. In general, the E2F family plays a crucial role in the control of cell cycle and action of tumour suppressor proteins and is also a target of the transforming proteins of small DNA tumour viruses [, ]Homo sapiens Mus musculus (Mouse) Macaca fascicularis (Crab eating macaque).
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Publication
18222992 | J:181670
First Author: Davies VJ
Year: 2008
Journal: Brain
Title: A missense mutation in the murine Opa3 gene models human Costeff syndrome.
Volume: 131
Issue: Pt 2
Pages: 368-80
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Protein
A2AWL7
Organism: Mus musculus/domesticus
Length: 3003  
Fragment?: false
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Protein
E9QLG3
Organism: Mus musculus/domesticus
Length: 3042  
Fragment?: false
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Protein
H7BX50
Organism: Mus musculus/domesticus
Length: 2833  
Fragment?: false
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Publication
15960975 | J:156231
First Author: Dou Y
Year: 2005
Journal: Cell
Title: Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.
Volume: 121
Issue: 6
Pages: 873-85
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Publication
7739537 | J:24522
First Author: Wu CL
Year: 1995
Journal: Mol Cell Biol
Title: In vivo association of E2F and DP family proteins.
Volume: 15
Issue: 5
Pages: 2536-46
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Protein
Q3ULI0
Organism: Mus musculus/domesticus
Length: 537  
Fragment?: true
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Protein
O54917
Organism: Mus musculus/domesticus
Length: 272  
Fragment?: false
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Protein
Q8VHT5
Organism: Mus musculus/domesticus
Length: 272  
Fragment?: false
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Protein
Q8BS58
Organism: Mus musculus/domesticus
Length: 201  
Fragment?: false
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Protein
Q8VHT4
Organism: Mus musculus/domesticus
Length: 237  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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