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Search results 101 to 187 out of 187 for Rbm8a

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Type Details Score
Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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GXD Expression
GXD Expression
   
Probe: MGI:7425117
Assay Type: RT-PCR
Annotation Date: 2023-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691019
Stage: TS19
Assay Id: MGI:7425169
Age: embryonic day 11.5
Image: 4
Specimen Label: Emx1-Cre; Rbm8a lox/+
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7425119
Assay Type: RT-PCR
Annotation Date: 2023-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691019
Stage: TS19
Assay Id: MGI:7425170
Age: embryonic day 11.5
Image: 4
Specimen Label: Emx1-Cre; Rbm8a lox/+
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7425121
Assay Type: RT-PCR
Annotation Date: 2023-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691019
Stage: TS19
Assay Id: MGI:7425171
Age: embryonic day 11.5
Image: S2
Specimen Label: Emx1-Cre; Rbm8a lox/+
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7425122
Assay Type: RT-PCR
Annotation Date: 2023-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691019
Stage: TS19
Assay Id: MGI:7425172
Age: embryonic day 11.5
Image: S2
Specimen Label: Emx1-Cre; Rbm8a lox/+
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7425125
Assay Type: RT-PCR
Annotation Date: 2023-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691019
Stage: TS19
Assay Id: MGI:7425175
Age: embryonic day 11.5
Image: 6
Specimen Label: Emx1-Cre; Rbm8a lox/+
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7425125
Assay Type: RT-PCR
Annotation Date: 2023-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691019
Stage: TS19
Assay Id: MGI:7425175
Age: embryonic day 11.5
Image: 6
Specimen Label: Emx1-Cre; Rbm8a lox/+
Detected: true
Specimen Num: 4
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Protein
Q9CWZ3
Organism: Mus musculus/domesticus
Length: 174  
Fragment?: false
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Publication
11013075 | -
First Author: Salicioni AM
Year: 2000
Journal: Genomics
Title: Identification and structural analysis of human RBM8A and RBM8B: two highly conserved RNA-binding motif proteins that interact with OVCA1, a candidate tumor suppressor.
Volume: 69
Issue: 1
Pages: 54-62
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Protein
Q9CWZ3-2
Organism: Mus musculus/domesticus
Length: 173  
Fragment?: false
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DO Term
DOID:14699 | thrombocytopenia-absent radius syndrome
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HT Experiment
GSE85576 | Transcriptome analyses of EJC haploinsufficient neocortices
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
1991323 | -
First Author: Robbins J
Year: 1991
Journal: Cell
Title: Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: identification of a class of bipartite nuclear targeting sequence.
Volume: 64
Issue: 3
Pages: 615-23
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Publication
11691839 | -
First Author: Mohr SE
Year: 2001
Journal: Genes Dev
Title: The RNA-binding protein Tsunagi interacts with Mago Nashi to establish polarity and localize oskar mRNA during Drosophila oogenesis.
Volume: 15
Issue: 21
Pages: 2886-99
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Protein Domain
IPR008111 | RNA-bd_8
Type: Family
Description: RNA-binding motif protein 8 (RBM8), also termed binder of OVCA1-1 (BOV-1) or RNA-binding protein Y14, is one of the components of the exon-exon junction complex (EJC) []. It has two isoforms, RBM8A and RBM8B, both of which are identical except that RBM8B is 16 amino acids shorter at its N terminus []. Three-dimensional modelling of the RBM8 RRM domain indicates that the sequences fold into an RNA-binding domain, forming a hydrophobic core between a β-sheet and two helices. The human RBM8A protein is ubiquitously expressed; the protein is localised predominantly in the cell nucleus and diffused throughout the cytoplasm []. It preferentially associates with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. Evidence suggests the protein remains associated with spliced mRNAs as a tag to indicate the position of spliced introns. Human RBM8A protein specifically binds to MAGOH, the human homologue of Drosophila mago nashi, a protein required for normal germ plasm development in the Drosophila embryo []; a similar association occurs with the Drosophila RBM8 protein, Tsunagi []. The RBM8A and RBM8B protein sequences contain a putative bipartite nuclear localisation signal []at the N terminus, as well a stretch of glycine residues. In addition, the RRM contained within RBM8A and RBM8B contains one set of the two consensus nucleic acid-binding motifs, RNP-1 and RNP-2, characteristic of heterogeneous nuclear ribonucleoprotein (hnRNP).
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Publication
29301961 | -
First Author: Zhan X
Year: 2018
Journal: Science
Title: Structure of a human catalytic step I spliceosome.
Volume: 359
Issue: 6375
Pages: 537-545
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Protein
A0A0G2JFX7
Organism: Mus musculus/domesticus
Length: 171  
Fragment?: false
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Protein
A0A0N4SUH6
Organism: Mus musculus/domesticus
Length: 174  
Fragment?: false
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Protein
A0A0G2JEA9
Organism: Mus musculus/domesticus
Length: 125  
Fragment?: false
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Publication
27780844 | J:240595
First Author: Mao H
Year: 2017
Journal: RNA
Title: Mouse models of Casc3 reveal developmental functions distinct from other components of the exon junction complex.
Volume: 23
Issue: 1
Pages: 23-31
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Protein Coding Gene
MGI:3612447 | Rbm8a2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CAROLIEiJ_G0014951 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0016844 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0016823 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0016789 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0016606 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_3612447 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0016187 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0016685 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0016682 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0017281 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0015974 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0016249 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_SPRETEiJ_G0015751 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:5490489
Assay Type: RT-PCR
Annotation Date: 2013-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287428
Stage: TS28
Assay Id: MGI:5490513
Age: postnatal adult
Specimen Label: None
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5490489
Assay Type: RT-PCR
Annotation Date: 2013-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287428
Stage: TS28
Assay Id: MGI:5490513
Age: postnatal adult
Specimen Label: None
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:5490489
Assay Type: RT-PCR
Annotation Date: 2013-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287428
Stage: TS28
Assay Id: MGI:5490513
Age: postnatal adult
Specimen Label: None
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:5490489
Assay Type: RT-PCR
Annotation Date: 2013-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5490513
Age: postnatal adult
Specimen Label: None
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:5490489
Assay Type: RT-PCR
Annotation Date: 2013-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:5490513
Age: postnatal adult
Specimen Label: None
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:5490489
Assay Type: RT-PCR
Annotation Date: 2013-06-17
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5490513
Age: postnatal adult
Specimen Label: None
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:5490489
Assay Type: RT-PCR
Annotation Date: 2013-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287423
Stage: TS23
Assay Id: MGI:5490520
Age: embryonic day 15.0
Specimen Label: None
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5490489
Assay Type: RT-PCR
Annotation Date: 2013-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287424
Stage: TS24
Assay Id: MGI:5490520
Age: embryonic day 16.5
Specimen Label: None
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:5490489
Assay Type: RT-PCR
Annotation Date: 2013-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283425
Stage: TS25
Assay Id: MGI:5490520
Age: embryonic day 17.0
Specimen Label: None
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:5490489
Assay Type: RT-PCR
Annotation Date: 2013-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283425
Stage: TS25
Assay Id: MGI:5490520
Age: embryonic day 17.0
Specimen Label: None
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:5490489
Assay Type: RT-PCR
Annotation Date: 2013-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283425
Stage: TS25
Assay Id: MGI:5490520
Age: embryonic day 17.0
Specimen Label: None
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:5490489
Assay Type: RT-PCR
Annotation Date: 2013-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283427
Stage: TS27
Assay Id: MGI:5490520
Age: postnatal newborn
Specimen Label: None
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:5490489
Assay Type: RT-PCR
Annotation Date: 2013-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283427
Stage: TS27
Assay Id: MGI:5490520
Age: postnatal newborn
Specimen Label: None
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:5490489
Assay Type: RT-PCR
Annotation Date: 2013-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283427
Stage: TS27
Assay Id: MGI:5490520
Age: postnatal newborn
Specimen Label: None
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:5490489
Assay Type: RT-PCR
Annotation Date: 2013-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3578428
Stage: TS28
Assay Id: MGI:5490579
Age: postnatal adult
Specimen Label: None
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5490489
Assay Type: RT-PCR
Annotation Date: 2013-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3578428
Stage: TS28
Assay Id: MGI:5490579
Age: postnatal adult
Specimen Label: None
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:5490489
Assay Type: RT-PCR
Annotation Date: 2013-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3577728
Stage: TS28
Assay Id: MGI:5490579
Age: postnatal adult
Specimen Label: None
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5490504
Assay Type: RNA in situ
Annotation Date: 2013-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1907828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5490550
Age: postnatal adult
Specimen Label: 5M
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:5490504
Assay Type: RNA in situ
Annotation Date: 2013-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283425
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:5490550
Age: embryonic day 17.0
Note: Expression was predominantly in the epithelial cells of the developing villus.
Specimen Label: 5K
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5490504
Assay Type: RNA in situ
Annotation Date: 2013-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3578427
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:5490550
Age: postnatal day 1
Note: Expression was predominantly in the epithelial cells of the villus.
Specimen Label: 5L
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5490504
Assay Type: RNA in situ
Annotation Date: 2013-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3578428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5490550
Age: postnatal adult
Specimen Label: 5M
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5490504
Assay Type: RNA in situ
Annotation Date: 2013-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3578428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5490550
Age: postnatal adult
Specimen Label: 5N
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:5490504
Assay Type: RNA in situ
Annotation Date: 2013-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3578428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5490550
Age: postnatal adult
Specimen Label: 5O
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:5490504
Assay Type: RNA in situ
Annotation Date: 2013-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3577728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5490550
Age: postnatal adult
Specimen Label: 5O
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:5490504
Assay Type: RNA in situ
Annotation Date: 2013-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1866828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5490550
Age: postnatal adult
Specimen Label: 5N
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:5490504
Assay Type: RNA in situ
Annotation Date: 2013-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1866828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5490550
Age: postnatal adult
Specimen Label: 5O
Detected: true
Specimen Num: 5
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Publication
19033377 | -
First Author: Nielsen KH
Year: 2009
Journal: RNA
Title: Mechanism of ATP turnover inhibition in the EJC.
Volume: 15
Issue: 1
Pages: 67-75
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Protein Domain
IPR033744 | RRM_RBM8
Type: Domain
Description: This entry corresponds to the RNA recognition motif of RBM8. RNA-binding protein RBM8, also termed binder of OVCA1-1 (BOV-1) or RNA-binding protein Y14, is one of the components of the exon-exon junction complex (EJC) []. It has two isoforms, RBM8A and RBM8B, both of which are identical except that RBM8B is 16 amino acids shorter at its N terminus []. RBM8, together with other EJC components (such as Magoh, Aly/REF, RNPS1, Srm160, and Upf3), plays critical roles in postsplicing processing, including nuclear export and cytoplasmic localization of the mRNA, and the nonsense-mediated mRNA decay (NMD) surveillance process. RBM8 binds to mRNA 20-24 nucleotides upstream of a spliced exon-exon junction. It is also involved in spliced mRNA nuclear export, and the process of nonsense-mediated decay of mRNAs with premature stop codons. RBM8 forms a specific heterodimer complex with the EJC protein Magoh which then associates with Aly/REF, RNPS1, DEK, and SRm160 on the spliced mRNA, and inhibits ATP turnover by eIF4AIII, thereby trapping the EJC core onto RNA [, ].RBM8 contains an N-terminal putative bipartite nuclear localization signal, one RNA recognition motif (RRM), also termed RBD (RNA binding domain) or RNP (ribonucleoprotein domain), in the central region, and a C-terminal serine-arginine rich region (SR domain) and glycine-arginine rich region (RG domain) [].
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Publication
12781131 | -
First Author: Lau CK
Year: 2003
Journal: Curr Biol
Title: Structure of the Y14-Magoh core of the exon junction complex.
Volume: 13
Issue: 11
Pages: 933-41
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Publication
16009965 | J:104317
First Author: Islam S
Year: 2005
Journal: J Histochem Cytochem
Title: Developmental and regional expression and localization of mRNAs encoding proteins involved in RNA translocation.
Volume: 53
Issue: 12
Pages: 1501-9
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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