Type |
Details |
Score |
Publication |
First Author: |
Matilainen T |
Year: |
2007 |
Journal: |
Int J Dev Biol |
Title: |
Analysis of Netrin 1 receptors during inner ear development. |
Volume: |
51 |
Issue: |
5 |
Pages: |
409-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lin S |
Year: |
2020 |
Journal: |
J Mol Cell Biol |
Title: |
Neogenin-loss in neural crest cells results in persistent hyperplastic primary vitreous formation. |
Volume: |
12 |
Issue: |
1 |
Pages: |
17-31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Leighton PA |
Year: |
2001 |
Journal: |
Nature |
Title: |
Defining brain wiring patterns and mechanisms through gene trapping in mice. |
Volume: |
410 |
Issue: |
6825 |
Pages: |
174-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kam JW |
Year: |
2016 |
Journal: |
Development |
Title: |
RGMB and neogenin control cell differentiation in the developing olfactory epithelium. |
Volume: |
143 |
Issue: |
9 |
Pages: |
1534-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yung AR |
Year: |
2018 |
Journal: |
Cell Rep |
Title: |
Netrin-1 Confines Rhombic Lip-Derived Neurons to the CNS. |
Volume: |
22 |
Issue: |
7 |
Pages: |
1666-1680 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bin JM |
Year: |
2015 |
Journal: |
Cell Rep |
Title: |
Complete Loss of Netrin-1 Results in Embryonic Lethality and Severe Axon Guidance Defects without Increased Neural Cell Death. |
Volume: |
12 |
Issue: |
7 |
Pages: |
1099-106 |
|
•
•
•
•
•
|
Publication |
First Author: |
Garrett AM |
Year: |
2016 |
Journal: |
Front Mol Neurosci |
Title: |
Analysis of Expression Pattern and Genetic Deletion of Netrin5 in the Developing Mouse. |
Volume: |
9 |
|
Pages: |
3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Leggere JC |
Year: |
2016 |
Journal: |
Elife |
Title: |
NOVA regulates Dcc alternative splicing during neuronal migration and axon guidance in the spinal cord. |
Volume: |
5 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Miyoshi G |
Year: |
2012 |
Journal: |
Neuron |
Title: |
Dynamic FoxG1 expression coordinates the integration of multipolar pyramidal neuron precursors into the cortical plate. |
Volume: |
74 |
Issue: |
6 |
Pages: |
1045-58 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yung AR |
Year: |
2015 |
Journal: |
Development |
Title: |
Phenotypic analysis of mice completely lacking netrin 1. |
Volume: |
142 |
Issue: |
21 |
Pages: |
3686-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Steele-Perkins G |
Year: |
2005 |
Journal: |
Mol Cell Biol |
Title: |
The transcription factor gene Nfib is essential for both lung maturation and brain development. |
Volume: |
25 |
Issue: |
2 |
Pages: |
685-98 |
|
•
•
•
•
•
|
Publication |
First Author: |
Quesnel-Vallières M |
Year: |
2015 |
Journal: |
Genes Dev |
Title: |
Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development. |
Volume: |
29 |
Issue: |
7 |
Pages: |
746-59 |
|
•
•
•
•
•
|
Publication |
First Author: |
Müller M |
Year: |
2003 |
Journal: |
Development |
Title: |
Nkx6.1 controls migration and axon pathfinding of cranial branchio-motoneurons. |
Volume: |
130 |
Issue: |
23 |
Pages: |
5815-26 |
|
•
•
•
•
•
|
Publication |
First Author: |
Poliak S |
Year: |
2015 |
Journal: |
Elife |
Title: |
Synergistic integration of Netrin and ephrin axon guidance signals by spinal motor neurons. |
Volume: |
4 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Brignani S |
Year: |
2020 |
Journal: |
Neuron |
Title: |
Remotely Produced and Axon-Derived Netrin-1 Instructs GABAergic Neuron Migration and Dopaminergic Substantia Nigra Development. |
Volume: |
107 |
Issue: |
4 |
Pages: |
684-702.e9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Luo PM |
Year: |
2023 |
Journal: |
Development |
Title: |
Stromal netrin 1 coordinates renal arteriogenesis and mural cell differentiation. |
Volume: |
150 |
Issue: |
22 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Fenske TS |
Year: |
2006 |
Journal: |
Cancer Res |
Title: |
Identification of candidate alkylator-induced cancer susceptibility genes by whole genome scanning in mice. |
Volume: |
66 |
Issue: |
10 |
Pages: |
5029-38 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gannoun L |
Year: |
2023 |
Journal: |
Development |
Title: |
Axon guidance genes control hepatic artery development. |
Volume: |
150 |
Issue: |
16 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Quilez S |
Year: |
2024 |
Journal: |
Front Cell Dev Biol |
Title: |
Loss of Neogenin alters branchial arch development and leads to craniofacial skeletal defects. |
Volume: |
12 |
|
Pages: |
1256465 |
|
•
•
•
•
•
|
Publication |
First Author: |
Brommage R |
Year: |
2014 |
Journal: |
Bone Res |
Title: |
High-throughput screening of mouse gene knockouts identifies established and novel skeletal phenotypes. |
Volume: |
2 |
|
Pages: |
14034 |
|
•
•
•
•
•
|
Publication |
First Author: |
Luo L |
Year: |
2020 |
Journal: |
Neuron |
Title: |
Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hald J |
Year: |
2012 |
Journal: |
Diabetologia |
Title: |
Pancreatic islet and progenitor cell surface markers with cell sorting potential. |
Volume: |
55 |
Issue: |
1 |
Pages: |
154-65 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen B |
Year: |
2005 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex. |
Volume: |
102 |
Issue: |
47 |
Pages: |
17184-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2001 |
|
Title: |
Gene Ontology Annotation by the MGI Curatorial Staff |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen J |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. |
Volume: |
100 |
Issue: |
17 |
Pages: |
9918-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGI and IMPC |
Year: |
2018 |
Journal: |
Database Release |
Title: |
MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bedogni F |
Year: |
2021 |
Journal: |
Front Mol Neurosci |
Title: |
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. |
Volume: |
14 |
|
Pages: |
686034 |
|
•
•
•
•
•
|
Publication |
First Author: |
Thompson CL |
Year: |
2014 |
Journal: |
Neuron |
Title: |
A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. |
Volume: |
83 |
Issue: |
2 |
Pages: |
309-323 |
|
•
•
•
•
•
|
Publication |
First Author: |
Visel A |
Year: |
2004 |
Journal: |
Nucleic Acids Res |
Title: |
GenePaint.org: an atlas of gene expression patterns in the mouse embryo. |
Volume: |
32 |
Issue: |
Database issue |
Pages: |
D552-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stryke D |
Year: |
2003 |
Journal: |
Nucleic Acids Res |
Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
Volume: |
31 |
Issue: |
1 |
Pages: |
278-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lennon G |
Year: |
1999 |
Journal: |
Database Download |
Title: |
WashU-HHMI Mouse EST Project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
International Mouse Strain Resource |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of germline transmission data for alleles from IMSR strain data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Helmholtz Zentrum Muenchen GmbH |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
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|
|
•
•
•
•
•
|
Publication |
First Author: |
GUDMAP Consortium |
Year: |
2004 |
Journal: |
www.gudmap.org |
Title: |
GUDMAP: the GenitoUrinary Development Molecular Anatomy Project |
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|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
|
Title: |
Rat to Mouse ISO GO annotation transfer |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Magdaleno S |
Year: |
2006 |
Journal: |
PLoS Biol |
Title: |
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
Volume: |
4 |
Issue: |
4 |
Pages: |
e86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
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•
•
•
•
•
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Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
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|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
|
Title: |
Human to Mouse ISO GO annotation transfer |
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•
•
•
•
•
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Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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•
•
•
•
•
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Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
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•
•
•
•
•
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Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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•
•
•
•
•
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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•
•
•
•
•
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
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|
•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
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|
|
•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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•
•
•
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•
|
Allele |
Name: |
transgene insertion B17-2, Michael I Kotlikoff |
Allele Type: |
Transgenic |
Attribute String: |
Reporter |
|
•
•
•
•
•
|
Publication |
First Author: |
Hagihara M |
Year: |
2011 |
Journal: |
J Biol Chem |
Title: |
Neogenin, a receptor for bone morphogenetic proteins. |
Volume: |
286 |
Issue: |
7 |
Pages: |
5157-65 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang Q |
Year: |
2015 |
Journal: |
Oncol Rep |
Title: |
Overexpression of neogenin inhibits cell proliferation and induces apoptosis in human MDA-MB-231 breast carcinoma cells. |
Volume: |
34 |
Issue: |
1 |
Pages: |
258-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rajagopalan S |
Year: |
2004 |
Journal: |
Nat Cell Biol |
Title: |
Neogenin mediates the action of repulsive guidance molecule. |
Volume: |
6 |
Issue: |
8 |
Pages: |
756-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wilson NH |
Year: |
2007 |
Journal: |
Int J Biochem Cell Biol |
Title: |
Neogenin: one receptor, many functions. |
Volume: |
39 |
Issue: |
5 |
Pages: |
874-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wilson NH |
Year: |
2006 |
Journal: |
Dev Biol |
Title: |
Neogenin interacts with RGMa and netrin-1 to guide axons within the embryonic vertebrate forebrain. |
Volume: |
296 |
Issue: |
2 |
Pages: |
485-98 |
|
•
•
•
•
•
|
Publication |
First Author: |
Matsunaga E |
Year: |
2004 |
Journal: |
Dev Growth Differ |
Title: |
Repulsive guidance molecule/neogenin: a novel ligand-receptor system playing multiple roles in neural development. |
Volume: |
46 |
Issue: |
6 |
Pages: |
481-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim SJ |
Year: |
2014 |
Journal: |
Oncotarget |
Title: |
Up-regulation of neogenin-1 increases cell proliferation and motility in gastric cancer. |
Volume: |
5 |
Issue: |
10 |
Pages: |
3386-98 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Neogenin (NEO1) is a multifunctional transmembrane receptor belonging to the immunoglobulin superfamily []. It displays identical secondary structure to DCC (deleted in colorectal cancer), a netrin receptor that is involved in axon guidance and cell survival. Similar to DCC, it is able to transduce signals elicited by netrin []. Netrin-Neogenin interactions result in a chemoattractive axon guidance response []. Neogenin is also a receptor for members of the repulsive guidance molecule (RGM) family, which act as a repulsive axon guidance cue [, , ]. RGM binding to NEO1 activates the bone morphogenetic protein (BMP)-regulated signalling involved in morphogenesis and iron homeostasis [, ].Neogenin has an important role in cancer development [, ]. |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion B10-3, Michael I Kotlikoff |
Allele Type: |
Transgenic |
Attribute String: |
Reporter |
|
•
•
•
•
•
|
Strain |
Attribute String: |
congenic, mutant strain, transgenic |
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant stock, transgenic |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
231
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Tian C |
Year: |
2013 |
Journal: |
Mol Reprod Dev |
Title: |
Repulsive guidance molecules (RGMs) and neogenin in bone morphogenetic protein (BMP) signaling. |
Volume: |
80 |
Issue: |
9 |
Pages: |
700-17 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1493
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
405
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1492
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1465
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee FK |
Year: |
2021 |
Journal: |
Elife |
Title: |
Genetically engineered mice for combinatorial cardiovascular optobiology. |
Volume: |
10 |
|
|
|
•
•
•
•
•
|