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Search results 101 to 200 out of 206 for Ddx6

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Type Details Score
Publication
8786135 | J:33856
First Author: Matsuda Y
Year: 1996
Journal: Genomics
Title: Comparative genome mapping of the ataxia-telangiectasia region in mouse, rat, and Syrian hamster.
Volume: 34
Issue: 3
Pages: 347-52
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Publication
34897463 | J:324707
 
First Author: Dhandapani L
Year: 2022
Journal: J Cell Sci
Title: Comparative analysis of vertebrates reveals that mouse primordial oocytes do not contain a Balbiani body.
Volume: 135
Issue: 1
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Publication
38088064 | J:343469
 
First Author: Ding Y
Year: 2023
Journal: Development
Title: Eif4enif1 haploinsufficiency disrupts oocyte mitochondrial dynamics and leads to subfertility.
Volume: 150
Issue: 23
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Publication
25456498 | J:217461
First Author: Yang G
Year: 2014
Journal: Neuron
Title: An eIF4E1/4E-T complex determines the genesis of neurons from precursors by translationally repressing a proneurogenic transcription program.
Volume: 84
Issue: 4
Pages: 723-39
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Publication
20133598 | J:157579
First Author: Suzuki A
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: NANOS2 interacts with the CCR4-NOT deadenylation complex and leads to suppression of specific RNAs.
Volume: 107
Issue: 8
Pages: 3594-9
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Publication
20011505 | J:155865
First Author: Aravin AA
Year: 2009
Journal: PLoS Genet
Title: Cytoplasmic compartmentalization of the fetal piRNA pathway in mice.
Volume: 5
Issue: 12
Pages: e1000764
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Publication
37889087 | J:342865
First Author: Wan Y
Year: 2023
Journal: Nucleic Acids Res
Title: LSM14B is essential for oocyte meiotic maturation by regulating maternal mRNA storage and clearance.
Volume: 51
Issue: 21
Pages: 11652-11667
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Publication
25416063 | J:217384
First Author: Suzuki A
Year: 2014
Journal: Biol Open
Title: Interaction of NANOS2 and NANOS3 with different components of the CNOT complex may contribute to the functional differences in mouse male germ cells.
Volume: 3
Issue: 12
Pages: 1207-16
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Publication
21436445 | J:169836
First Author: Lachke SA
Year: 2011
Journal: Science
Title: Mutations in the RNA granule component TDRD7 cause cataract and glaucoma.
Volume: 331
Issue: 6024
Pages: 1571-6
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Publication
20059948 | J:156018
First Author: Shoji M
Year: 2009
Journal: Dev Cell
Title: The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline.
Volume: 17
Issue: 6
Pages: 775-87
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Publication
15979417 | J:103128
First Author: Machka C
Year: 2005
Journal: Gene Expr Patterns
Title: Identification of Dll1 (Delta1) target genes during mouse embryogenesis using differential expression profiling.
Volume: 6
Issue: 1
Pages: 94-101
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Publication
38310234 | J:345099
First Author: Wang X
Year: 2024
Journal: BMC Genomics
Title: Identification and analysis of key circRNAs in the mouse embryonic ovary provides insight into primordial follicle development.
Volume: 25
Issue: 1
Pages: 139
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Publication
26120033 | J:239655
First Author: Zhou Z
Year: 2015
Journal: Dev Cell
Title: RNA Binding Protein Nanos2 Organizes Post-transcriptional Buffering System to Retain Primitive State of Mouse Spermatogonial Stem Cells.
Volume: 34
Issue: 1
Pages: 96-107
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Publication
31330130 | J:282329
First Author: Hildebrandt MR
Year: 2019
Journal: Dev Biol
Title: Cytoplasmic aggregation of DDX1 in developing embryos: Early embryonic lethality associated with Ddx1 knockout.
Volume: 455
Issue: 2
Pages: 420-433
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Publication
35103284 | J:321979
 
First Author: Kurz J
Year: 2022
Journal: Development
Title: Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter.
Volume: 149
Issue: 4
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Publication
30916783 | J:279388
First Author: Weiss AC
Year: 2019
Journal: J Pathol
Title: Delayed onset of smooth muscle cell differentiation leads to hydroureter formation in mice with conditional loss of the zinc finger transcription factor gene Gata2 in the ureteric mesenchyme.
Volume: 248
Issue: 4
Pages: 452-463
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
18973680 | J:141291
 
First Author: Tamplin OJ
Year: 2008
Journal: BMC Genomics
Title: Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives.
Volume: 9
Pages: 511
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Publication
- | J:72245
       
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
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Publication
- | J:66660
       
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:342608
       
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Gene
471936 | LOC471936
Type: gene
Organism: chimpanzee
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Gene
479071 | LOC479071
Type: gene
Organism: dog, domestic
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Gene
100613894 | LOC100613894
Type: gene
Organism: chimpanzee
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UniProt Feature
UniProt Feature
Begin: 281
Description: DDX6 binding motif
Type: short sequence motif
End: 311
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Gene
100424142 | LOC100424142
Type: gene
Organism: macaque, rhesus
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Gene
100426345 | LOC100426345
Type: gene
Organism: macaque, rhesus
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UniProt Feature
UniProt Feature
Begin: 1
Description: Probable ATP-dependent RNA helicase DDX6
Type: chain
End: 483
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Publication
26098573 | -
First Author: Hu G
Year: 2015
Journal: Nat Cell Biol
Title: A conserved mechanism of TOR-dependent RCK-mediated mRNA degradation regulates autophagy.
Volume: 17
Issue: 7
Pages: 930-942
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Protein
P54823
Organism: Mus musculus/domesticus
Length: 483  
Fragment?: false
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Publication
17392519 | -
First Author: Nonhoff U
Year: 2007
Journal: Mol Biol Cell
Title: Ataxin-2 interacts with the DEAD/H-box RNA helicase DDX6 and interferes with P-bodies and stress granules.
Volume: 18
Issue: 4
Pages: 1385-96
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Publication
20639877 | J:162534
First Author: Glasmacher E
Year: 2010
Journal: Nat Immunol
Title: Roquin binds inducible costimulator mRNA and effectors of mRNA decay to induce microRNA-independent post-transcriptional repression.
Volume: 11
Issue: 8
Pages: 725-33
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Publication
21726813 | J:174373
First Author: Su H
Year: 2011
Journal: Mol Cell
Title: Mammalian hyperplastic discs homolog EDD regulates miRNA-mediated gene silencing.
Volume: 43
Issue: 1
Pages: 97-109
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Protein Domain
IPR025852 | SM_dom_ATX
Type: Domain
Description: This SM domain is found in Ataxin-2 [, ]. This domain has been shown to interact with RNA helicase DDX6 [].Ataxin-2 has many functions, such as endocytic receptor cycling [], translational regulation, embryonic development [], energy metabolism and weight regulation []. Mutations of the Ataxin-2 gene cause spinocerebellar ataxia 2 (SCA2), a neurodegenerative disorder leading to predominant loss of Purkinje cells in the cerebellum and impairment of motor coordination []. In SCA2, expansion of a CAG repeat in exon 1 of the Ataxin-2 (ATXN2) gene causes expansion of a polyQ domain in the ATXN2 protein []. ATXN2 has been shown to interact with many proteins. It interacts with multiple RNA-binding proteins (RBPs), staufen, IP3R, RGS8 mRNA, endophilins and CIN85 [].
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Publication
29661911 | J:264835
 
First Author: Christou-Kent M
Year: 2018
Journal: EMBO Mol Med
Title: PATL2 is a key actor of oocyte maturation whose invalidation causes infertility in women and mice.
Volume: 10
Issue: 5
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Publication
32024018 | J:297882
 
First Author: Hansen M
Year: 2020
Journal: Int J Mol Sci
Title: The RNA-Binding Protein ATXN2 is Expressed during Megakaryopoiesis and May Control Timing of Gene Expression.
Volume: 21
Issue: 3
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Publication
23637887 | J:200561
First Author: Chiang PY
Year: 2013
Journal: PLoS One
Title: Phosphorylation of mRNA decapping protein Dcp1a by the ERK signaling pathway during early differentiation of 3T3-L1 preadipocytes.
Volume: 8
Issue: 4
Pages: e61697
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Publication
9462862 | -
First Author: Neuwald AF
Year: 1998
Journal: J Mol Med (Berl)
Title: Ataxin-2, global regulators of bacterial gene expression, and spliceosomal snRNP proteins share a conserved domain.
Volume: 76
Issue: 1
Pages: 3-5
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Publication
11917006 | -
First Author: Anantharaman V
Year: 2002
Journal: Nucleic Acids Res
Title: Comparative genomics and evolution of proteins involved in RNA metabolism.
Volume: 30
Issue: 7
Pages: 1427-64
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Publication
16115810 | -
First Author: Ralser M
Year: 2005
Journal: Hum Mol Genet
Title: Ataxin-2 and huntingtin interact with endophilin-A complexes to function in plastin-associated pathways.
Volume: 14
Issue: 19
Pages: 2893-909
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Protein Domain
IPR009604 | LsmAD_domain
Type: Domain
Description: This domain can be found in eukaryotic ataxin-2 []. Ataxin-2 is predicted to consist of mostly non-globular domains []. This domain has been shown to interact with RNA helicase DDX6 [].Ataxin-2 has many functions, such as endocytic receptor cycling [], translational regulation, embryonic development [], energy metabolism and weight regulation []. Mutations of the Ataxin-2 gene cause spinocerebellar ataxia 2 (SCA2), a neurodegenerative disorder leading to predominant loss of Purkinje cells in the cerebellum and impairment of motor coordination []. In SCA2, expansion of a CAG repeat in exon 1 of the Ataxin-2 (ATXN2) gene causes expansion of a polyQ domain in the ATXN2 protein []. ATXN2 has been shown to interact with many proteins. It interacts with multiple RNA-binding proteins (RBPs), staufen, IP3R, RGS8 mRNA, endophilins and CIN85 [].Proteins containing this domain also include Pbp1 from budding yeasts, Pbp1 interacts with Pab1 to regulate mRNA polyadenylation [, ]. It promotes mating-type switching in mother cells by positively regulating HO mRNA translation []and forms a condensate in response to respiratory status to regulate TORC1 signaling []. It is also involved in P-body-dependent granule assembly [].
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Publication
18602463 | -
First Author: Nonis D
Year: 2008
Journal: Cell Signal
Title: Ataxin-2 associates with the endocytosis complex and affects EGF receptor trafficking.
Volume: 20
Issue: 10
Pages: 1725-39
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Protein
Q7TQH0
Organism: Mus musculus/domesticus
Length: 1049  
Fragment?: false
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Publication
8896555 | J:20378
First Author: Pulst SM
Year: 1996
Journal: Nat Genet
Title: Moderate expansion of a normally biallelic trinucleotide repeat in spinocerebellar ataxia type 2.
Volume: 14
Issue: 3
Pages: 269-76
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Protein
A0A0U1RPL0
Organism: Mus musculus/domesticus
Length: 1096  
Fragment?: false
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Protein
E9Q5Q0
Organism: Mus musculus/domesticus
Length: 863  
Fragment?: true
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Protein
Q3TYH7
Organism: Mus musculus/domesticus
Length: 890  
Fragment?: false
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Protein
Q3TGG2
Organism: Mus musculus/domesticus
Length: 994  
Fragment?: false
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Publication
25902068 | J:224692
First Author: Dansithong W
Year: 2015
Journal: PLoS Genet
Title: Ataxin-2 regulates RGS8 translation in a new BAC-SCA2 transgenic mouse model.
Volume: 11
Issue: 4
Pages: e1005182
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Publication
15342467 | -
First Author: Ciosk R
Year: 2004
Journal: Development
Title: ATX-2, the C. elegans ortholog of ataxin 2, functions in translational regulation in the germline.
Volume: 131
Issue: 19
Pages: 4831-41
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Publication
16293225 | J:103805
First Author: Kiehl TR
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Generation and characterization of Sca2 (ataxin-2) knockout mice.
Volume: 339
Issue: 1
Pages: 17-24
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Publication
29427103 | -
 
First Author: Scoles DR
Year: 2018
Journal: Adv Exp Med Biol
Title: Spinocerebellar Ataxia Type 2.
Volume: 1049
Pages: 175-195
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Protein
J3QP59
Organism: Mus musculus/domesticus
Length: 218  
Fragment?: true
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Publication
9819425 | -
First Author: Mangus DA
Year: 1998
Journal: Mol Cell Biol
Title: Pbp1p, a factor interacting with Saccharomyces cerevisiae poly(A)-binding protein, regulates polyadenylation.
Volume: 18
Issue: 12
Pages: 7383-96
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Publication
15121841 | -
First Author: Mangus DA
Year: 2004
Journal: Mol Cell Biol
Title: Identification of factors regulating poly(A) tail synthesis and maturation.
Volume: 24
Issue: 10
Pages: 4196-206
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Publication
30982600 | -
First Author: Yang YS
Year: 2019
Journal: Cell
Title: Yeast Ataxin-2 Forms an Intracellular Condensate Required for the Inhibition of TORC1 Signaling during Respiratory Growth.
Volume: 177
Issue: 3
Pages: 697-710.e17
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Publication
18981231 | -
First Author: Buchan JR
Year: 2008
Journal: J Cell Biol
Title: P bodies promote stress granule assembly in Saccharomyces cerevisiae.
Volume: 183
Issue: 3
Pages: 441-55
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Protein
O70305
Organism: Mus musculus/domesticus
Length: 1285  
Fragment?: false
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Protein
E9QM77
Organism: Mus musculus/domesticus
Length: 1286  
Fragment?: false
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Protein
A0A286YDU2
Organism: Mus musculus/domesticus
Length: 402  
Fragment?: true
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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