|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 601 to 700 out of 762 for Ncam2

<< First    < Previous  |  Next >    Last >>
0.061s

Categories

Hits by Strain

Hits by Category

Type Details Score
Publication
26111164 | J:274088
First Author: Higuera C
Year: 2015
Journal: PLoS One
Title: Self-Organizing Feature Maps Identify Proteins Critical to Learning in a Mouse Model of Down Syndrome.
Volume: 10
Issue: 6
Pages: e0129126
•
•
•
•
•
Publication
26702072 | J:229599
 
First Author: Cramer NP
Year: 2015
Journal: Physiol Rep
Title: Altered intrinsic and network properties of neocortical neurons in the Ts65Dn mouse model of Down syndrome.
Volume: 3
Issue: 12
•
•
•
•
•
Publication
37449271 | J:337836
 
First Author: Overk C
Year: 2023
Journal: Front Neurosci
Title: Modeling Alzheimer's disease related phenotypes in the Ts65Dn mouse: impact of age on Aβ, Tau, pTau, NfL, and behavior.
Volume: 17
Pages: 1202208
•
•
•
•
•
Publication
22214338 | J:180732
First Author: Ahmed MM
Year: 2012
Journal: J Proteome Res
Title: Loss of correlations among proteins in brains of the Ts65Dn mouse model of down syndrome.
Volume: 11
Issue: 2
Pages: 1251-63
•
•
•
•
•
Publication
22776132 | J:203590
First Author: Rachubinski AL
Year: 2012
Journal: Exp Gerontol
Title: Modulating cognitive deficits and tau accumulation in a mouse model of aging Down syndrome through neonatal implantation of neural progenitor cells.
Volume: 47
Issue: 9
Pages: 723-33
•
•
•
•
•
Publication
36587842 | J:339507
 
First Author: Sarver DC
Year: 2023
Journal: Mol Metab
Title: Dysregulated systemic metabolism in a Down syndrome mouse model.
Volume: 68
Pages: 101666
•
•
•
•
•
Publication
30237765 | J:276008
 
First Author: Duval N
Year: 2018
Journal: Front Aging Neurosci
Title: Rapamycin Treatment Ameliorates Age-Related Accumulation of Toxic Metabolic Intermediates in Brains of the Ts65Dn Mouse Model of Down Syndrome and Aging.
Volume: 10
Pages: 263
•
•
•
•
•
Publication
27457036 | J:238238
 
First Author: Stagni F
Year: 2016
Journal: Neuroscience
Title: Short- and long-term effects of neonatal pharmacotherapy with epigallocatechin-3-gallate on hippocampal development in the Ts65Dn mouse model of Down syndrome.
Volume: 333
Pages: 277-301
•
•
•
•
•
Publication
22728103 | J:192516
 
First Author: Vidal V
Year: 2012
Journal: Neuroscience
Title: Lack of behavioral and cognitive effects of chronic ethosuximide and gabapentin treatment in the Ts65Dn mouse model of Down syndrome.
Volume: 220
Pages: 158-68
•
•
•
•
•
Publication
9666356 | J:48496
First Author: Cefalu JA
Year: 1998
Journal: Growth Dev Aging
Title: Jejunal function and plasma amino acid concentrations in the segmental trisomic Ts65Dn mouse.
Volume: 62
Issue: 1-2
Pages: 47-59
•
•
•
•
•
Publication
24068809 | J:202685
First Author: Gutierrez-Castellanos N
Year: 2013
Journal: J Neurosci
Title: Size does not always matter: Ts65Dn Down syndrome mice show cerebellum-dependent motor learning deficits that cannot be rescued by postnatal SAG treatment.
Volume: 33
Issue: 39
Pages: 15408-13
•
•
•
•
•
Publication
17959791 | J:127045
First Author: Chakrabarti L
Year: 2007
Journal: J Neurosci
Title: Defects in embryonic neurogenesis and initial synapse formation in the forebrain of the Ts65Dn mouse model of Down syndrome.
Volume: 27
Issue: 43
Pages: 11483-95
•
•
•
•
•
Publication
17146725 | J:147556
First Author: Stewart LS
Year: 2007
Journal: Behav Genet
Title: Chronobiometry of behavioral activity in the Ts65Dn model of Down syndrome.
Volume: 37
Issue: 2
Pages: 388-98
•
•
•
•
•
Publication
37191946 | J:341973
First Author: Alldred MJ
Year: 2023
Journal: FASEB J
Title: Basal forebrain cholinergic neurons are vulnerable in a mouse model of Down syndrome and their molecular fingerprint is rescued by maternal choline supplementation.
Volume: 37
Issue: 6
Pages: e22944
•
•
•
•
•
Publication
31944407 | J:292739
First Author: Hamlett ED
Year: 2020
Journal: Glia
Title: RvE1 treatment prevents memory loss and neuroinflammation in the Ts65Dn mouse model of Down syndrome.
Volume: 68
Issue: 7
Pages: 1347-1360
•
•
•
•
•
Publication
18591654 | J:137826
First Author: Voronov SV
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Synaptojanin 1-linked phosphoinositide dyshomeostasis and cognitive deficits in mouse models of Down's syndrome.
Volume: 105
Issue: 27
Pages: 9415-20
•
•
•
•
•
Publication
27840230 | J:238270
 
First Author: Powers BE
Year: 2017
Journal: Neuroscience
Title: Maternal choline supplementation in a mouse model of Down syndrome: Effects on attention and nucleus basalis/substantia innominata neuron morphology in adult offspring.
Volume: 340
Pages: 501-514
•
•
•
•
•
Publication
38047317 | J:345569
First Author: Brandauer J
Year: 2024
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Senescent hearts from male Ts65Dn mice exhibit preserved function but altered size and nicotinamide adenine dinucleotide pathway signaling.
Volume: 326
Issue: 2
Pages: R176-R183
•
•
•
•
•
Publication
17428201 | J:129637
First Author: Hill CA
Year: 2007
Journal: J Anat
Title: Effects of aneuploidy on skull growth in a mouse model of Down syndrome.
Volume: 210
Issue: 4
Pages: 394-405
•
•
•
•
•
Publication
17950473 | J:130535
First Author: Fernandez F
Year: 2008
Journal: Behav Brain Res
Title: Episodic-like memory in Ts65Dn, a mouse model of Down syndrome.
Volume: 188
Issue: 1
Pages: 233-7
•
•
•
•
•
Publication
20007548 | J:160280
First Author: Ng AP
Year: 2010
Journal: Blood
Title: Trisomy of Erg is required for myeloproliferation in a mouse model of Down syndrome.
Volume: 115
Issue: 19
Pages: 3966-9
•
•
•
•
•
Publication
21447382 | J:172069
First Author: Shichiri M
Year: 2011
Journal: Free Radic Biol Med
Title: α-Tocopherol suppresses lipid peroxidation and behavioral and cognitive impairments in the Ts65Dn mouse model of Down syndrome.
Volume: 50
Issue: 12
Pages: 1801-11
•
•
•
•
•
Publication
26696850 | J:244854
 
First Author: Catuara-Solarz S
Year: 2015
Journal: Front Behav Neurosci
Title: Principal Component Analysis of the Effects of Environmental Enrichment and (-)-epigallocatechin-3-gallate on Age-Associated Learning Deficits in a Mouse Model of Down Syndrome.
Volume: 9
Pages: 330
•
•
•
•
•
Publication
27288239 | J:236805
First Author: Sansevero G
Year: 2016
Journal: Exp Neurol
Title: Experience-dependent reduction of soluble β-amyloid oligomers and rescue of cognitive abilities in middle-age Ts65Dn mice, a model of Down syndrome.
Volume: 283
Issue: Pt A
Pages: 49-56
•
•
•
•
•
Publication
23432468 | J:202187
First Author: Lorenzo LP
Year: 2013
Journal: Immunology
Title: Defective thymic progenitor development and mature T-cell responses in a mouse model for Down syndrome.
Volume: 139
Issue: 4
Pages: 447-58
•
•
•
•
•
Publication
20532168 | J:161812
First Author: Netzer WJ
Year: 2010
Journal: PLoS One
Title: Lowering beta-amyloid levels rescues learning and memory in a Down syndrome mouse model.
Volume: 5
Issue: 6
Pages: e10943
•
•
•
•
•
Publication
19056491 | J:145541
First Author: Roper RJ
Year: 2009
Journal: Mech Dev
Title: A neural crest deficit in Down syndrome mice is associated with deficient mitotic response to Sonic hedgehog.
Volume: 126
Issue: 3-4
Pages: 212-9
•
•
•
•
•
Publication
35988873 | J:328253
 
First Author: Alemany-González M
Year: 2022
Journal: Neurobiol Dis
Title: Postnatal environmental enrichment enhances memory through distinct neural mechanisms in healthy and trisomic female mice.
Volume: 173
Pages: 105841
•
•
•
•
•
Publication
31040160 | J:288511
 
First Author: Day SM
Year: 2019
Journal: eNeuro
Title: Glucagon-Like Peptide-1 Cleavage Product Improves Cognitive Function in a Mouse Model of Down Syndrome.
Volume: 6
Issue: 2
•
•
•
•
•
Publication
22284618 | J:181873
 
First Author: Mitra A
Year: 2012
Journal: Brain Res
Title: Developmentally altered inhibition in Ts65Dn, a mouse model of Down syndrome.
Volume: 1440
Pages: 1-8
•
•
•
•
•
Publication
33633179 | J:303842
First Author: Starbuck JM
Year: 2021
Journal: Sci Rep
Title: Green tea extracts containing epigallocatechin-3-gallate modulate facial development in Down syndrome.
Volume: 11
Issue: 1
Pages: 4715
•
•
•
•
•
Publication
25632113 | J:218976
First Author: Fortress AM
Year: 2015
Journal: J Neurosci
Title: Designer receptors enhance memory in a mouse model of Down syndrome.
Volume: 35
Issue: 4
Pages: 1343-53
•
•
•
•
•
Publication
28624415 | J:259957
 
First Author: Dekker AD
Year: 2017
Journal: Neurobiol Dis
Title: Aging rather than aneuploidy affects monoamine neurotransmitters in brain regions of Down syndrome mouse models.
Volume: 105
Pages: 235-244
•
•
•
•
•
Publication
19765102 | J:154717
First Author: Han F
Year: 2009
Journal: Int J Exp Pathol
Title: Otitis media in a mouse model for Down syndrome.
Volume: 90
Issue: 5
Pages: 480-8
•
•
•
•
•
Publication
26254735 | J:227674
 
First Author: Giacomini A
Year: 2015
Journal: Neurobiol Dis
Title: Inhibition of APP gamma-secretase restores Sonic Hedgehog signaling and neurogenesis in the Ts65Dn mouse model of Down syndrome.
Volume: 82
Pages: 385-396
•
•
•
•
•
Publication
15854777 | J:97980
First Author: Rueda N
Year: 2005
Journal: Neurosci Lett
Title: Cell proliferation is reduced in the dentate gyrus of aged but not young Ts65Dn mice, a model of Down syndrome.
Volume: 380
Issue: 1-2
Pages: 197-201
•
•
•
•
•
Publication
22916188 | J:190052
First Author: Fowler TW
Year: 2012
Journal: PLoS One
Title: Low bone turnover and low BMD in Down syndrome: effect of intermittent PTH treatment.
Volume: 7
Issue: 8
Pages: e42967
•
•
•
•
•
Publication
24740065 | J:208833
First Author: Letourneau A
Year: 2014
Journal: Nature
Title: Domains of genome-wide gene expression dysregulation in Down's syndrome.
Volume: 508
Issue: 7496
Pages: 345-50
•
•
•
•
•
Publication
22627164 | J:186437
 
First Author: Usowicz MM
Year: 2012
Journal: Brain Res
Title: Increased excitability and altered action potential waveform in cerebellar granule neurons of the Ts65Dn mouse model of Down syndrome.
Volume: 1465
Pages: 10-7
•
•
•
•
•
Publication
25774849 | J:228180
First Author: Deidda G
Year: 2015
Journal: Nat Med
Title: Reversing excitatory GABAAR signaling restores synaptic plasticity and memory in a mouse model of Down syndrome.
Volume: 21
Issue: 4
Pages: 318-26
•
•
•
•
•
Publication
23220201 | J:197665
 
First Author: Altafaj X
Year: 2013
Journal: Neurobiol Dis
Title: Normalization of Dyrk1A expression by AAV2/1-shDyrk1A attenuates hippocampal-dependent defects in the Ts65Dn mouse model of Down syndrome.
Volume: 52
Pages: 117-27
•
•
•
•
•
Publication
18755166 | J:147643
 
First Author: Necchi D
Year: 2008
Journal: Brain Res
Title: Axonal abnormalities in cerebellar Purkinje cells of the Ts65Dn mouse.
Volume: 1238
Pages: 181-8
•
•
•
•
•
Publication
26244989 | J:227677
 
First Author: Begenisic T
Year: 2015
Journal: Neurobiol Dis
Title: Early environmental therapy rescues brain development in a mouse model of Down syndrome.
Volume: 82
Pages: 409-419
•
•
•
•
•
Publication
19453946 | J:150749
First Author: Fernandez F
Year: 2009
Journal: J Neurochem
Title: Normal protein composition of synapses in Ts65Dn mice: a mouse model of Down syndrome.
Volume: 110
Issue: 1
Pages: 157-69
•
•
•
•
•
Publication
23516277 | J:231261
First Author: Tyler WA
Year: 2013
Journal: J Neurosci
Title: Multiplex genetic fate mapping reveals a novel route of neocortical neurogenesis, which is altered in the Ts65Dn mouse model of Down syndrome.
Volume: 33
Issue: 12
Pages: 5106-19
•
•
•
•
•
Publication
21266456 | J:170123
First Author: Trazzi S
Year: 2011
Journal: Hum Mol Genet
Title: APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome.
Volume: 20
Issue: 8
Pages: 1560-73
•
•
•
•
•
Publication
37890559 | J:342378
 
First Author: Gautier MK
Year: 2023
Journal: Neurobiol Dis
Title: Maternal choline supplementation protects against age-associated cholinergic and GABAergic basal forebrain neuron degeneration in the Ts65Dn mouse model of Down syndrome and Alzheimer's disease.
Volume: 188
Pages: 106332
•
•
•
•
•
Publication
21527343 | J:173180
First Author: Faizi M
Year: 2011
Journal: Neurobiol Dis
Title: Comprehensive behavioral phenotyping of Ts65Dn mouse model of Down syndrome: activation of β1-adrenergic receptor by xamoterol as a potential cognitive enhancer.
Volume: 43
Issue: 2
Pages: 397-413
•
•
•
•
•
Publication
10718292 | J:103600
First Author: Huang W
Year: 2000
Journal: Neuroreport
Title: Brain myo-inositol level is elevated in Ts65Dn mouse and reduced after lithium treatment.
Volume: 11
Issue: 3
Pages: 445-8
•
•
•
•
•
Publication
33947925 | J:316336
First Author: Victorino DB
Year: 2021
Journal: Sci Rep
Title: Atypical electrophysiological and behavioral responses to diazepam in a leading mouse model of Down syndrome.
Volume: 11
Issue: 1
Pages: 9521
•
•
•
•
•
Publication
10553065 | J:58452
First Author: Paz-Miguel JE
Year: 1999
Journal: J Immunol
Title: Reactive oxygen intermediates during programmed cell death induced in the thymus of the Ts(1716)65Dn mouse, a murine model for human Down's syndrome.
Volume: 163
Issue: 10
Pages: 5399-410
•
•
•
•
•
Publication
23202733 | J:194179
First Author: Contestabile A
Year: 2013
Journal: J Clin Invest
Title: Lithium rescues synaptic plasticity and memory in Down syndrome mice.
Volume: 123
Issue: 1
Pages: 348-61
•
•
•
•
•
Publication
23115123 | J:264420
First Author: Cowley PM
Year: 2012
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Functional and biochemical characterization of soleus muscle in Down syndrome mice: insight into the muscle dysfunction seen in the human condition.
Volume: 303
Issue: 12
Pages: R1251-60
•
•
•
•
•
Publication
17093127 | J:135917
First Author: Best TK
Year: 2007
Journal: J Neurophysiol
Title: Ts65Dn, a mouse model of Down syndrome, exhibits increased GABAB-induced potassium current.
Volume: 97
Issue: 1
Pages: 892-900
•
•
•
•
•
Publication
29203796 | J:287490
First Author: Parrini M
Year: 2017
Journal: Sci Rep
Title: Aerobic exercise and a BDNF-mimetic therapy rescue learning and memory in a mouse model of Down syndrome.
Volume: 7
Issue: 1
Pages: 16825
•
•
•
•
•
Genotype
Genotype
Symbol: Ts(17<16>)65Dn/?
Background: involves: C3H/HeSnJ * C57BL/6JEi * DBA/2J
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Ts(17<16>)65Dn/?
Background: involves: C3H/HeJ * C57BL/6 * DBA/2J
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Ts(17<16>)65Dn/?
Background: involves: DBA/2J
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Ts(17<16>)65Dn/?
Background: involves: C3H * C57BL/6 * DBA/2J
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Ts(17<16>)65Dn/?
Background: involves: C3H/HeJ * C57BL/6JEi * DBA/2J
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Ts(17<16>)65Dn/?
Background: B6EiC3Sn a/A-Ts(17<16>)65Dn/J
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Rcan1/Rcan1<+> Ts(17<16>)65Dn/?
Background: involves: 129S4/SvJae * C3H/HeSn * C57BL/6 * C57BL/6Ei * DBA/2J
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Ts(17<16>)65Dn/?
Background: B6EiC3Sn.BLiA-Ts(17<16>)65Dn/DnJ
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Ts(17<16>)65Dn/?
Background: involves: C3H/HeJ * C57BL/6J * DBA/2J
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Del(16App-Runx1)5Yah/? Ts(17<16>)65Dn/?
Background: involves: BALB/c * C3H * C57BL/6 * DBA/2J
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Ts(17<16>)65Dn/?
Background: involves: C3H/HeH * C3H/HeSn * C57BL/6Ei * C57BL/6J * DBA/2J
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Ts(17<16>)65Dn/?
Background: involves: BALB/c * C3H/He * C57BL/6JEiJ * DBA/2J
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Ts(17<16>)65Dn/?
Background: involves: C3H * C57BL/6
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Del(16Lipi-Ncam2)8Yey/+ Dp(16Lipi-Zbtb21)1Yey/?
Background: involves: 129S7/SvEvBrd
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Publication
23524343 | J:198375
First Author: Wang X
Year: 2013
Journal: Nat Med
Title: Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down's syndrome.
Volume: 19
Issue: 4
Pages: 473-80
•
•
•
•
•
Publication
25556111 | J:217672
 
First Author: Blazek JD
Year: 2015
Journal: Mech Dev
Title: Abnormal mineralization of the Ts65Dn Down syndrome mouse appendicular skeleton begins during embryonic development in a Dyrk1a-independent manner.
Volume: 136
Pages: 133-42
•
•
•
•
•
Publication
28172997 | J:241781
First Author: McElyea SD
Year: 2016
Journal: Hum Mol Genet
Title: Influence of prenatal EGCG treatment and Dyrk1a dosage reduction on craniofacial features associated with Down syndrome.
Volume: 25
Issue: 22
Pages: 4856-4869
•
•
•
•
•
Publication
26206885 | J:226041
First Author: Blazek JD
Year: 2015
Journal: Hum Mol Genet
Title: Rescue of the abnormal skeletal phenotype in Ts65Dn Down syndrome mice using genetic and therapeutic modulation of trisomic Dyrk1a.
Volume: 24
Issue: 20
Pages: 5687-96
•
•
•
•
•
Publication
37992782 | J:343255
 
First Author: Hawley LE
Year: 2023
Journal: Neurobiol Dis
Title: Sex-specific developmental alterations in DYRK1A expression in the brain of a Down syndrome mouse model.
Volume: 190
Pages: 106359
•
•
•
•
•
Publication
28647555 | J:260246
 
First Author: García-Cerro S
Year: 2017
Journal: Neurobiol Dis
Title: Normalizing the gene dosage of Dyrk1A in a mouse model of Down syndrome rescues several Alzheimer's disease phenotypes.
Volume: 106
Pages: 76-88
•
•
•
•
•
Publication
35716916 | J:326829
 
First Author: Sherman KM
Year: 2022
Journal: Bone
Title: Low bone mass and impaired fracture healing in mouse models of Trisomy21 (Down syndrome).
Volume: 162
Pages: 116471
•
•
•
•
•
Publication
28993310 | J:245580
First Author: Herault Y
Year: 2017
Journal: Dis Model Mech
Title: Rodent models in Down syndrome research: impact and future opportunities.
Volume: 10
Issue: 10
Pages: 1165-1186
•
•
•
•
•
Strain
MGI:2163627 | B6EiC3Sn a/A-Ts(17<16>)65Dn/J
Attribute String: mutant strain, chromosome aberration, trisomy
•
•
•
•
•
Publication
23920041 | J:205302
First Author: Tlili A
Year: 2013
Journal: Mol Genet Metab
Title: DYRK1A overexpression decreases plasma lecithin:cholesterol acyltransferase activity and apolipoprotein A-I levels.
Volume: 110
Issue: 3
Pages: 371-7
•
•
•
•
•
Publication
26208718 | J:224143
 
First Author: Polk RC
Year: 2015
Journal: BMC Dev Biol
Title: The pattern of congenital heart defects arising from reduced Tbx5 expression is altered in a Down syndrome mouse model.
Volume: 15
Pages: 30
•
•
•
•
•
Publication
19458618 | J:150286
First Author: Baek KH
Year: 2009
Journal: Nature
Title: Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1.
Volume: 459
Issue: 7250
Pages: 1126-30
•
•
•
•
•
Publication
21953411 | J:178872
First Author: Duchon A
Year: 2011
Journal: Mamm Genome
Title: Identification of the translocation breakpoints in the Ts65Dn and Ts1Cje mouse lines: relevance for modeling Down syndrome.
Volume: 22
Issue: 11-12
Pages: 674-84
•
•
•
•
•
Publication
36995257 | J:335483
 
First Author: Moyer AJ
Year: 2023
Journal: Dis Model Mech
Title: Overexpression screen of chromosome 21 genes reveals modulators of Sonic hedgehog signaling relevant to Down syndrome.
Volume: 16
Issue: 4
•
•
•
•
•
Publication
8884947 | J:174274
First Author: Klein SL
Year: 1996
Journal: Physiol Behav
Title: Characterization of sensorimotor performance, reproductive and aggressive behaviors in segmental trisomic 16 (Ts65Dn) mice.
Volume: 60
Issue: 4
Pages: 1159-64
•
•
•
•
•
Publication
20600907 | J:163008
First Author: Toiber D
Year: 2010
Journal: Neurobiol Dis
Title: Engineering DYRK1A overdosage yields Down syndrome-characteristic cortical splicing aberrations.
Volume: 40
Issue: 1
Pages: 348-59
•
•
•
•
•
Publication
25540129 | J:219589
First Author: Singh N
Year: 2015
Journal: Dis Model Mech
Title: Acute upregulation of hedgehog signaling in mice causes differential effects on cranial morphology.
Volume: 8
Issue: 3
Pages: 271-9
•
•
•
•
•
Publication
32416604 | J:296087
First Author: Victorino DB
Year: 2020
Journal: Invest Ophthalmol Vis Sci
Title: Quantitative Analysis of Retinal Structure and Function in Two Chromosomally Altered Mouse Models of Down Syndrome.
Volume: 61
Issue: 5
Pages: 25
•
•
•
•
•
Publication
33027640 | J:300542
First Author: Pinto B
Year: 2020
Journal: Neuron
Title: Rescuing Over-activated Microglia Restores Cognitive Performance in Juvenile Animals of the Dp(16) Mouse Model of Down Syndrome.
Volume: 108
Issue: 5
Pages: 887-904.e12
•
•
•
•
•
Publication
18282758 | J:136520
First Author: Colas D
Year: 2008
Journal: Neurobiol Dis
Title: Sleep and EEG features in genetic models of Down syndrome.
Volume: 30
Issue: 1
Pages: 1-7
•
•
•
•
•
Publication
20870049 | J:170199
First Author: Blazek JD
Year: 2011
Journal: Bone
Title: Disruption of bone development and homeostasis by trisomy in Ts65Dn Down syndrome mice.
Volume: 48
Issue: 2
Pages: 275-80
•
•
•
•
•
Publication
36289231 | J:330574
First Author: Fulton SL
Year: 2022
Journal: Nat Commun
Title: Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome.
Volume: 13
Issue: 1
Pages: 6384
•
•
•
•
•
Publication
16783527 | J:174334
First Author: Harashima C
Year: 2006
Journal: Cell Mol Neurobiol
Title: Elevated expression of the G-protein-activated inwardly rectifying potassium channel 2 (GIRK2) in cerebellar unipolar brush cells of a Down syndrome mouse model.
Volume: 26
Issue: 4-6
Pages: 719-34
•
•
•
•
•
Publication
15515178 | J:94569
First Author: Belichenko PV
Year: 2004
Journal: J Comp Neurol
Title: Synaptic structural abnormalities in the Ts65Dn mouse model of Down Syndrome.
Volume: 480
Issue: 3
Pages: 281-98
•
•
•
•
•
Publication
15859352 | J:96650
First Author: Villar AJ
Year: 2005
Journal: Mamm Genome
Title: Identification and characterization of a new Down syndrome model, Ts[Rb(12.1716)]2Cje, resulting from a spontaneous Robertsonian fusion between T(171)65Dn and mouse chromosome 12.
Volume: 16
Issue: 2
Pages: 79-90
•
•
•
•
•
Publication
25511459 | J:217683
 
First Author: Dutka T
Year: 2015
Journal: Mech Dev
Title: Chronic up-regulation of the SHH pathway normalizes some developmental effects of trisomy in Ts65Dn mice.
Volume: 135
Pages: 68-80
•
•
•
•
•
Publication
26923405 | J:234508
 
First Author: Jiang Y
Year: 2016
Journal: Neurobiol Aging
Title: Partial BACE1 reduction in a Down syndrome mouse model blocks Alzheimer-related endosomal anomalies and cholinergic neurodegeneration: role of APP-CTF.
Volume: 39
Pages: 90-8
•
•
•
•
•
Publication
30685352 | J:277908
 
First Author: Navarro-Romero A
Year: 2019
Journal: Neurobiol Dis
Title: Cannabinoid type-1 receptor blockade restores neurological phenotypes in two models for Down syndrome.
Volume: 125
Pages: 92-106
•
•
•
•
•
Publication
28899917 | J:253021
First Author: William CM
Year: 2017
Journal: J Neurosci
Title: Activity-Dependent Dysfunction in Visual and Olfactory Sensory Systems in Mouse Models of Down Syndrome.
Volume: 37
Issue: 41
Pages: 9880-9888
•
•
•
•
•
Publication
24076652 | J:202008
First Author: Xu JC
Year: 2013
Journal: EMBO J
Title: Usp16: key controller of stem cells in Down syndrome.
Volume: 32
Issue: 21
Pages: 2788-9
•
•
•
•
•
Publication
24788405 | J:294518
First Author: Starbuck JM
Year: 2014
Journal: Am J Med Genet A
Title: Overlapping trisomies for human chromosome 21 orthologs produce similar effects on skull and brain morphology of Dp(16)1Yey and Ts65Dn mice.
Volume: 164A
Issue: 8
Pages: 1981-1990
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom