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Search results 1 to 100 out of 169 for L3mbtl2

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0.037s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: Lethal(3)malignant brain tumor-like protein 2 (L3MBTL2) binds to methylated histones, monomethylated and dimethylated 'Lys-20' on histone H4 and monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27' on histone H3 []. It is a component of the E2F6.com-1 complex in G0 phase of the cell cycle []. L3MBTL2 contains four MBT repeats and an FCS-type zinc finger [].
Publication
First Author: Meng C
Year: 2019
Journal: Cell Death Differ
Title: L3MBTL2 regulates chromatin remodeling during spermatogenesis.
Volume: 26
Issue: 11
Pages: 2194-2207
Gene
Type: gene
Organism: human
Publication
First Author: Qin J
Year: 2012
Journal: Cell Stem Cell
Title: The polycomb group protein L3mbtl2 assembles an atypical PRC1-family complex that is essential in pluripotent stem cells and early development.
Volume: 11
Issue: 3
Pages: 319-32
Publication
First Author: Lechtenberg BC
Year: 2009
Journal: Protein Sci
Title: Solution structure of the FCS zinc finger domain of the human polycomb group protein L(3)mbt-like 2.
Volume: 18
Issue: 3
Pages: 657-61
Publication
First Author: Guo Y
Year: 2009
Journal: Nucleic Acids Res
Title: Methylation-state-specific recognition of histones by the MBT repeat protein L3MBTL2.
Volume: 37
Issue: 7
Pages: 2204-10
GXD Expression      
Probe: MGI:2682815
Assay Type: Northern blot
Annotation Date: 2004-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:2683309
Age: embryonic day 11.0
Specimen Label: 11
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2682815
Assay Type: Northern blot
Annotation Date: 2004-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2683314
Age: postnatal adult
Specimen Label: liver
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2682815
Assay Type: Northern blot
Annotation Date: 2004-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2683314
Age: postnatal adult
Specimen Label: spleen
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:2682815
Assay Type: Northern blot
Annotation Date: 2004-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287428
Stage: TS28
Assay Id: MGI:2683314
Age: postnatal adult
Specimen Label: intestine
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:2682815
Assay Type: Northern blot
Annotation Date: 2004-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2683314
Age: postnatal adult
Specimen Label: brain
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:5902514
Assay Type: Northern blot
Annotation Date: 2017-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1683328
Stage: TS28
Assay Id: MGI:5902518
Age: postnatal adult
Specimen Label: Esophagus
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5902514
Assay Type: Northern blot
Annotation Date: 2017-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1893928
Stage: TS28
Assay Id: MGI:5902518
Age: postnatal adult
Specimen Label: Colon
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5902514
Assay Type: Northern blot
Annotation Date: 2017-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5902518
Age: postnatal adult
Specimen Label: Lung
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:5902514
Assay Type: Northern blot
Annotation Date: 2017-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:5902518
Age: postnatal adult
Specimen Label: Spleen
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:5902514
Assay Type: Northern blot
Annotation Date: 2017-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5902518
Age: postnatal adult
Specimen Label: Testis
Detected: true
Specimen Num: 13
GXD Expression        
Probe: MGI:5902514
Assay Type: Northern blot
Annotation Date: 2017-06-15
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3271528
Stage: TS28
Assay Id: MGI:5902518
Age: postnatal adult
Specimen Label: Muscle
Specimen Num: 16
GXD Expression      
Probe: MGI:5902514
Assay Type: Northern blot
Annotation Date: 2017-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5902518
Age: postnatal adult
Specimen Label: Brain
Detected: true
Specimen Num: 19
GXD Expression    
Probe: MGI:6150651
Assay Type: Immunohistochemistry
Annotation Date: 2018-04-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:160414
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:6150677
Age: embryonic day 3.5
Specimen Label: 3A Blastocyst
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:6150651
Assay Type: Immunohistochemistry
Annotation Date: 2018-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160404
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:6150677
Age: embryonic day 3.0
Note: Gradually increased expression between the 4-cell and morula stages.
Specimen Label: 3A Morula
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:6150651
Assay Type: Immunohistochemistry
Annotation Date: 2018-04-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:160362
Pattern: Not Specified
Stage: TS02
Assay Id: MGI:6150677
Age: embryonic day 1.0
Note: Significantly decreased expression.
Specimen Label: 3A 2-cell
Detected: true
Specimen Num: 3
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication  
First Author: Markus J
Year: 2003
Journal: Gene
Title: Proliferation-linked expression of the novel murine gene m4mbt encoding a nuclear zinc finger protein with four mbt domains.
Volume: 319
Pages: 117-26
GXD Expression      
Probe: MGI:2682815
Assay Type: Northern blot
Annotation Date: 2004-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:2683309
Age: embryonic day 7.0
Specimen Label: 7
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2682815
Assay Type: Northern blot
Annotation Date: 2004-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:2683309
Age: embryonic day 15.0
Specimen Label: 15
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2682815
Assay Type: Northern blot
Annotation Date: 2004-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:2683309
Age: embryonic day 17.0
Specimen Label: 17
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:2682815
Assay Type: Northern blot
Annotation Date: 2004-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:2683314
Age: postnatal adult
Specimen Label: heart
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2682815
Assay Type: Northern blot
Annotation Date: 2004-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2683314
Age: postnatal adult
Specimen Label: lung
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2682815
Assay Type: Northern blot
Annotation Date: 2004-01-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1702128
Stage: TS28
Assay Id: MGI:2683314
Age: postnatal adult
Specimen Label: stomach
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:2682815
Assay Type: Northern blot
Annotation Date: 2004-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2683314
Age: postnatal adult
Specimen Label: kidney
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:2682815
Assay Type: Northern blot
Annotation Date: 2004-01-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3557728
Stage: TS28
Assay Id: MGI:2683314
Age: postnatal adult
Specimen Label: muscle
Detected: false
Specimen Num: 8
GXD Expression      
Probe: MGI:2682815
Assay Type: Northern blot
Annotation Date: 2004-01-08
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2683314
Age: postnatal adult
Specimen Label: testes
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:2682815
Assay Type: Northern blot
Annotation Date: 2004-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276028
Stage: TS28
Assay Id: MGI:2683314
Age: postnatal adult
Specimen Label: bone marrow
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:2682815
Assay Type: Northern blot
Annotation Date: 2004-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:2683314
Age: postnatal adult
Specimen Label: thymus
Detected: true
Specimen Num: 12
GXD Expression      
Probe: MGI:5902514
Assay Type: Northern blot
Annotation Date: 2017-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702128
Stage: TS28
Assay Id: MGI:5902518
Age: postnatal adult
Specimen Label: Stomach
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5902514
Assay Type: Northern blot
Annotation Date: 2017-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283428
Stage: TS28
Assay Id: MGI:5902518
Age: postnatal adult
Specimen Label: Small bowel
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5902514
Assay Type: Northern blot
Annotation Date: 2017-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5902518
Age: postnatal adult
Specimen Label: Liver
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5902514
Assay Type: Northern blot
Annotation Date: 2017-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5902518
Age: postnatal adult
Specimen Label: Heart
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:5902514
Assay Type: Northern blot
Annotation Date: 2017-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5902518
Age: postnatal adult
Specimen Label: Kidney
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:5902514
Assay Type: Northern blot
Annotation Date: 2017-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276028
Stage: TS28
Assay Id: MGI:5902518
Age: postnatal adult
Specimen Label: Bone marrow
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:5902514
Assay Type: Northern blot
Annotation Date: 2017-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:5902518
Age: postnatal adult
Specimen Label: Thymus
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:5902514
Assay Type: Northern blot
Annotation Date: 2017-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:5902518
Age: postnatal adult
Specimen Label: Ovary
Detected: true
Specimen Num: 12
GXD Expression      
Probe: MGI:5902514
Assay Type: Northern blot
Annotation Date: 2017-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:5902518
Age: postnatal adult
Specimen Label: Uterus
Detected: true
Specimen Num: 14
GXD Expression      
Probe: MGI:5902514
Assay Type: Northern blot
Annotation Date: 2017-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:5902518
Age: postnatal adult
Specimen Label: Skin
Detected: true
Specimen Num: 15
GXD Expression      
Probe: MGI:5902514
Assay Type: Northern blot
Annotation Date: 2017-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:5902518
Age: postnatal adult
Specimen Label: Eyes
Detected: true
Specimen Num: 17
GXD Expression      
Probe: MGI:5902514
Assay Type: Northern blot
Annotation Date: 2017-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1832128
Stage: TS28
Assay Id: MGI:5902518
Age: postnatal adult
Specimen Label: Bladder
Detected: true
Specimen Num: 18
GXD Expression  
Probe: MGI:6150651
Assay Type: Immunohistochemistry
Annotation Date: 2018-04-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:318643
Pattern: Not Specified
Stage: TS03
Assay Id: MGI:6150677
Age: embryonic day 2.0
Note: Gradually increased expression between the 4-cell and morula stages.
Specimen Label: 3A 4-cell
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:6150651
Assay Type: Immunohistochemistry
Annotation Date: 2018-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160331
Pattern: Not Specified
Stage: TS01
Assay Id: MGI:6150677
Age: embryonic day 0.5
Note: Present on both pronuclei.
Specimen Label: 3A Zygote
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:6150651
Assay Type: Immunohistochemistry
Annotation Date: 2018-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318653
Pattern: Not Specified
Stage: TS03
Assay Id: MGI:6150677
Age: embryonic day 2.5
Note: Gradually increased expression between the 4-cell and morula stages.
Specimen Label: 3A 8-cell
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:6150651
Assay Type: Immunohistochemistry
Annotation Date: 2018-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360354
Pattern: Diffuse
Stage: TS04
Assay Id: MGI:6150677
Age: embryonic day 3.5
Note: More diffuse signal, with high background.
Specimen Label: 3A Blastocyst
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:6150651
Assay Type: Immunohistochemistry
Annotation Date: 2018-04-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:160464
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:6150677
Age: embryonic day 3.5
Specimen Label: 3A Blastocyst
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:6150651
Assay Type: Immunohistochemistry
Annotation Date: 2018-04-12
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6150677
Age: postnatal
Note: Expressed a rather uniform nuclear localization, but was excluded from the DAPI-rich regions.
Specimen Label: 3A oocyte
Detected: true
Specimen Num: 1
Protein
Organism: Mus musculus/domesticus
Length: 138  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 703  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 703  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 618  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 739  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 713  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 393  
Fragment?: false
Publication
First Author: Ogawa H
Year: 2002
Journal: Science
Title: A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells.
Volume: 296
Issue: 5570
Pages: 1132-6
Publication
First Author: Eid A
Year: 2016
Journal: Epigenetics
Title: Characterization of non-canonical Polycomb Repressive Complex 1 subunits during early mouse embryogenesis.
Volume: 11
Issue: 6
Pages: 389-97
Publication
First Author: Arai S
Year: 2005
Journal: EMBO J
Title: Impaired maturation of myeloid progenitors in mice lacking novel Polycomb group protein MBT-1.
Volume: 24
Issue: 10
Pages: 1863-73
Publication
First Author: Perez-Garcia V
Year: 2018
Journal: Nature
Title: Placentation defects are highly prevalent in embryonic lethal mouse mutants.
Volume: 555
Issue: 7697
Pages: 463-468
Publication      
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
Publication
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81