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Search results 101 to 200 out of 525 for Bace1

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Type Details Score
Publication
23504710 | J:199954
First Author: Sachse CC
Year: 2013
Journal: FASEB J
Title: BACE1 and presenilin/γ-secretase regulate proteolytic processing of KCNE1 and 2, auxiliary subunits of voltage-gated potassium channels.
Volume: 27
Issue: 6
Pages: 2458-67
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Publication
26454161 | J:251329
First Author: Agsten M
Year: 2015
Journal: J Mol Cell Cardiol
Title: BACE1 modulates gating of KCNQ1 (Kv7.1) and cardiac delayed rectifier KCNQ1/KCNE1 (IKs).
Volume: 89
Issue: Pt B
Pages: 335-48
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Publication
33208500 | J:338513
 
First Author: Lomoio S
Year: 2020
Journal: Sci Transl Med
Title: Gga3 deletion and a GGA3 rare variant associated with late onset Alzheimer's disease trigger BACE1 accumulation in axonal swellings.
Volume: 12
Issue: 570
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Publication
22052506 | J:262505
First Author: Velanac V
Year: 2012
Journal: Glia
Title: Bace1 processing of NRG1 type III produces a myelin-inducing signal but is not essential for the stimulation of myelination.
Volume: 60
Issue: 2
Pages: 203-17
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Publication
20886088 | J:165103
First Author: Devi L
Year: 2010
Journal: PLoS One
Title: Phospho-eIF2α level is important for determining abilities of BACE1 reduction to rescue cholinergic neurodegeneration and memory defects in 5XFAD mice.
Volume: 5
Issue: 9
Pages: e12974
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Publication
26563932 | J:259424
 
First Author: Natunen T
Year: 2016
Journal: Neurobiol Dis
Title: Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models.
Volume: 85
Pages: 187-205
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Publication
28502705 | J:251833
First Author: Shi Z
Year: 2017
Journal: Biochim Biophys Acta
Title: BAG-1M co-activates BACE1 transcription through NF-κB and accelerates Aβ production and memory deficit in Alzheimer's disease mouse model.
Volume: 1863
Issue: 9
Pages: 2398-2407
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Publication
24889041 | J:218077
First Author: Devi L
Year: 2014
Journal: Neurobiol Aging
Title: PERK mediates eIF2α phosphorylation responsible for BACE1 elevation, CREB dysfunction and neurodegeneration in a mouse model of Alzheimer's disease.
Volume: 35
Issue: 10
Pages: 2272-81
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Publication
26314636 | J:227527
 
First Author: Devi L
Year: 2015
Journal: Neuroscience
Title: Effects of BACE1 haploinsufficiency on APP processing and Aβ concentrations in male and female 5XFAD Alzheimer mice at different disease stages.
Volume: 307
Pages: 128-37
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Publication
20453200 | J:164465
First Author: Liu M
Year: 2010
Journal: J Lipid Res
Title: PCSK9 is not involved in the degradation of LDL receptors and BACE1 in the adult mouse brain.
Volume: 51
Issue: 9
Pages: 2611-8
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Publication
24797530 | J:316129
First Author: Login H
Year: 2015
Journal: Brain Struct Funct
Title: Activity-dependent and graded BACE1 expression in the olfactory epithelium is mediated by the retinoic acid metabolizing enzyme CYP26B1.
Volume: 220
Issue: 4
Pages: 2143-57
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Publication
30837353 | J:292991
 
First Author: Haroon MM
Year: 2019
Journal: J Biosci
Title: Delivery of BACE1 siRNA mediated by TARBP-BTP fusion protein reduces β-amyloid deposits in a transgenic mouse model of Alzheimer's disease.
Volume: 44
Issue: 1
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Publication
23507144 | J:202419
First Author: Barroso E
Year: 2013
Journal: Biochim Biophys Acta
Title: Tau hyperphosphorylation and increased BACE1 and RAGE levels in the cortex of PPARβ/δ-null mice.
Volume: 1832
Issue: 8
Pages: 1241-8
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Publication
20595388 | J:166179
First Author: Liang B
Year: 2010
Journal: J Biol Chem
Title: Calpain activation promotes BACE1 expression, amyloid precursor protein processing, and amyloid plaque formation in a transgenic mouse model of Alzheimer disease.
Volume: 285
Issue: 36
Pages: 27737-44
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Publication
21795680 | J:176738
First Author: Griffiths HH
Year: 2011
Journal: J Biol Chem
Title: Prion protein interacts with BACE1 protein and differentially regulates its activity toward wild type and Swedish mutant amyloid precursor protein.
Volume: 286
Issue: 38
Pages: 33489-500
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Publication
25481013 | J:217376
First Author: Wang Q
Year: 2014
Journal: Dis Model Mech
Title: Triptolide treatment reduces Alzheimer's disease (AD)-like pathology through inhibition of BACE1 in a transgenic mouse model of AD.
Volume: 7
Issue: 12
Pages: 1385-95
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Publication
22204380 | J:315486
 
First Author: Rajapaksha TW
Year: 2011
Journal: Mol Neurodegener
Title: The Alzheimer's β-secretase enzyme BACE1 is required for accurate axon guidance of olfactory sensory neurons and normal glomerulus formation in the olfactory bulb.
Volume: 6
Pages: 88
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Publication
25384422 | J:218214
First Author: Parr C
Year: 2015
Journal: FASEB J
Title: Activation of the Wnt/β-catenin pathway represses the transcription of the β-amyloid precursor protein cleaving enzyme (BACE1) via binding of T-cell factor-4 to BACE1 promoter.
Volume: 29
Issue: 2
Pages: 623-35
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Publication
22223639 | J:182773
First Author: Sadleir KR
Year: 2012
Journal: J Biol Chem
Title: Cdk5 protein inhibition and Aβ42 increase BACE1 protein level in primary neurons by a post-transcriptional mechanism: implications of CDK5 as a therapeutic target for Alzheimer disease.
Volume: 287
Issue: 10
Pages: 7224-35
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Publication
15364953 | J:337599
First Author: Kitazume S
Year: 2005
Journal: J Biol Chem
Title: In vivo cleavage of alpha2,6-sialyltransferase by Alzheimer beta-secretase.
Volume: 280
Issue: 9
Pages: 8589-95
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Publication
15080893 | J:89370
First Author: Pastorino L
Year: 2004
Journal: Mol Cell Neurosci
Title: BACE (beta-secretase) modulates the processing of APLP2 in vivo.
Volume: 25
Issue: 4
Pages: 642-9
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Publication
20163459 | J:169511
First Author: Sala Frigerio C
Year: 2010
Journal: FEBS J
Title: beta-Secretase cleavage is not required for generation of the intracellular C-terminal domain of the amyloid precursor family of proteins.
Volume: 277
Issue: 6
Pages: 1503-18
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Publication
15509532 | J:93635
First Author: Willem M
Year: 2004
Journal: Am J Pathol
Title: beta-site amyloid precursor protein cleaving enzyme 1 increases amyloid deposition in brain parenchyma but reduces cerebrovascular amyloid angiopathy in aging BACE x APP[V717I] double-transgenic mice.
Volume: 165
Issue: 5
Pages: 1621-31
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Publication
10531052 | J:43334
First Author: Vassar R
Year: 1999
Journal: Science
Title: Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE.
Volume: 286
Issue: 5440
Pages: 735-41
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Publication
34500034 | J:312957
 
First Author: Dai L
Year: 2021
Journal: Brain Behav Immun
Title: Elevated β-secretase 1 expression mediates CD4+ T cell dysfunction via PGE2 signalling in Alzheimer's disease.
Volume: 98
Pages: 337-348
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Publication
15824102 | J:100272
First Author: Wong HK
Year: 2005
Journal: J Biol Chem
Title: beta Subunits of voltage-gated sodium channels are novel substrates of beta-site amyloid precursor protein-cleaving enzyme (BACE1) and gamma-secretase.
Volume: 280
Issue: 24
Pages: 23009-17
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Publication
28004339 | J:325881
First Author: Stertz L
Year: 2018
Journal: Mol Neurobiol
Title: BACE1-Deficient Mice Exhibit Alterations in Immune System Pathways.
Volume: 55
Issue: 1
Pages: 709-717
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Publication
31110178 | J:275557
First Author: Liebsch F
Year: 2019
Journal: Nat Commun
Title: Aβ34 is a BACE1-derived degradation intermediate associated with amyloid clearance and Alzheimer's disease progression.
Volume: 10
Issue: 1
Pages: 2240
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Publication
20092570 | J:157228
First Author: Zhang XM
Year: 2009
Journal: Eur J Neurosci
Title: Beta-secretase-1 elevation in transgenic mouse models of Alzheimer's disease is associated with synaptic/axonal pathology and amyloidogenesis: implications for neuritic plaque development.
Volume: 30
Issue: 12
Pages: 2271-83
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Publication
17409228 | J:119403
First Author: Zhao J
Year: 2007
Journal: J Neurosci
Title: Beta-site amyloid precursor protein cleaving enzyme 1 levels become elevated in neurons around amyloid plaques: implications for Alzheimer's disease pathogenesis.
Volume: 27
Issue: 14
Pages: 3639-49
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Publication
18986979 | J:146980
First Author: Boissonneault V
Year: 2009
Journal: J Biol Chem
Title: MicroRNA-298 and microRNA-328 regulate expression of mouse beta-amyloid precursor protein-converting enzyme 1.
Volume: 284
Issue: 4
Pages: 1971-81
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Publication
18650431 | J:142478
First Author: Cole SL
Year: 2008
Journal: J Biol Chem
Title: The role of amyloid precursor protein processing by BACE1, the beta-secretase, in Alzheimer disease pathophysiology.
Volume: 283
Issue: 44
Pages: 29621-5
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Publication
22895721 | J:187719
First Author: Chen Y
Year: 2012
Journal: J Neurosci
Title: Alzheimer's β-secretase (BACE1) regulates the cAMP/PKA/CREB pathway independently of β-amyloid.
Volume: 32
Issue: 33
Pages: 11390-5
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Publication
16420434 | J:105376
First Author: Ohno M
Year: 2006
Journal: Eur J Neurosci
Title: Temporal memory deficits in Alzheimer's mouse models: rescue by genetic deletion of BACE1.
Volume: 23
Issue: 1
Pages: 251-60
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Publication
17470798 | J:121585
First Author: Ma H
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Involvement of beta-site APP cleaving enzyme 1 (BACE1) in amyloid precursor protein-mediated enhancement of memory and activity-dependent synaptic plasticity.
Volume: 104
Issue: 19
Pages: 8167-72
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Publication
20731874 | J:163907
 
First Author: Hitt BD
Year: 2010
Journal: Mol Neurodegener
Title: BACE1-/- mice exhibit seizure activity that does not correlate with sodium channel level or axonal localization.
Volume: 5
Pages: 31
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Publication
25912880 | J:235920
First Author: Paredes RM
Year: 2015
Journal: Genes Brain Behav
Title: Physiological and behavioral effects of amphetamine in BACE1(-/-) mice.
Volume: 14
Issue: 5
Pages: 411-8
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Publication
27791018 | J:238803
First Author: Katsouri L
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: PPARγ-coactivator-1α gene transfer reduces neuronal loss and amyloid-β generation by reducing β-secretase in an Alzheimer's disease model.
Volume: 113
Issue: 43
Pages: 12292-12297
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Publication
20505099 | J:160819
First Author: McAllister C
Year: 2010
Journal: J Neurosci
Title: Genetic targeting aromatase in male amyloid precursor protein transgenic mice down-regulates beta-secretase (BACE1) and prevents Alzheimer-like pathology and cognitive impairment.
Volume: 30
Issue: 21
Pages: 7326-34
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Publication
16027115 | J:102154
First Author: Rockenstein E
Year: 2005
Journal: J Biol Chem
Title: High beta-secretase activity elicits neurodegeneration in transgenic mice despite reductions in amyloid-beta levels: implications for the treatment of Alzheimer disease.
Volume: 280
Issue: 38
Pages: 32957-67
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Publication
17157415 | J:135007
First Author: Wang L
Year: 2008
Journal: Neurobiol Aging
Title: Activation of protein kinase C modulates BACE1-mediated beta-secretase activity.
Volume: 29
Issue: 3
Pages: 357-67
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Publication
25955795 | J:329858
First Author: Yang G
Year: 2015
Journal: Mol Med Rep
Title: MicroRNA-29c targets β-site amyloid precursor protein-cleaving enzyme 1 and has a neuroprotective role in vitro and in vivo.
Volume: 12
Issue: 2
Pages: 3081-8
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Publication
15606899 | J:95653
First Author: Wickham L
Year: 2005
Journal: J Neurochem
Title: Beta-amyloid protein converting enzyme 1 and brain-specific type II membrane protein BRI3: binding partners processed by furin.
Volume: 92
Issue: 1
Pages: 93-102
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Publication
26139848 | J:325924
First Author: Dislich B
Year: 2015
Journal: Mol Cell Proteomics
Title: Label-free Quantitative Proteomics of Mouse Cerebrospinal Fluid Detects β-Site APP Cleaving Enzyme (BACE1) Protease Substrates In Vivo.
Volume: 14
Issue: 10
Pages: 2550-63
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Publication
15584902 | J:94803
First Author: Yang HC
Year: 2004
Journal: J Neurochem
Title: Biochemical and kinetic characterization of BACE1: investigation into the putative species-specificity for beta- and beta'-cleavage sites by human and murine BACE1.
Volume: 91
Issue: 6
Pages: 1249-59
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Publication
24907271 | J:216006
First Author: He W
Year: 2014
Journal: J Biol Chem
Title: β-site amyloid precursor protein cleaving enzyme 1(BACE1) regulates Notch signaling by controlling the cleavage of Jagged 1 (Jag1) and Jagged 2 (Jag2) proteins.
Volume: 289
Issue: 30
Pages: 20630-7
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Publication
16990514 | J:113726
First Author: Willem M
Year: 2006
Journal: Science
Title: Control of peripheral nerve myelination by the beta-secretase BACE1.
Volume: 314
Issue: 5799
Pages: 664-6
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Publication
15987683 | J:100925
First Author: Dominguez D
Year: 2005
Journal: J Biol Chem
Title: Phenotypic and biochemical analyses of BACE1- and BACE2-deficient mice.
Volume: 280
Issue: 35
Pages: 30797-806
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Publication
23430253 | J:336904
First Author: Stützer I
Year: 2013
Journal: J Biol Chem
Title: Systematic proteomic analysis identifies β-site amyloid precursor protein cleaving enzyme 2 and 1 (BACE2 and BACE1) substrates in pancreatic β-cells.
Volume: 288
Issue: 15
Pages: 10536-47
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Publication
22903875 | J:280845
First Author: Cai J
Year: 2012
Journal: EMBO Mol Med
Title: β-Secretase (BACE1) inhibition causes retinal pathology by vascular dysregulation and accumulation of age pigment.
Volume: 4
Issue: 9
Pages: 980-91
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Publication
30456346 | J:284846
First Author: Voytyuk I
Year: 2018
Journal: Life Sci Alliance
Title: BACE2 distribution in major brain cell types and identification of novel substrates.
Volume: 1
Issue: 1
Pages: e201800026
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Publication
21825135 | J:175989
First Author: Sannerud R
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: ADP ribosylation factor 6 (ARF6) controls amyloid precursor protein (APP) processing by mediating the endosomal sorting of BACE1.
Volume: 108
Issue: 34
Pages: E559-68
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Publication
27084579 | J:246510
First Author: Kurkinen KM
Year: 2016
Journal: J Cell Sci
Title: SEPT8 modulates β-amyloidogenic processing of APP by affecting the sorting and accumulation of BACE1.
Volume: 129
Issue: 11
Pages: 2224-38
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Publication
26663083 | J:259402
First Author: Schnöder L
Year: 2016
Journal: J Biol Chem
Title: Deficiency of Neuronal p38α MAPK Attenuates Amyloid Pathology in Alzheimer Disease Mouse and Cell Models through Facilitating Lysosomal Degradation of BACE1.
Volume: 291
Issue: 5
Pages: 2067-79
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Publication
18660751 | J:138995
First Author: Jonas MC
Year: 2008
Journal: EMBO Rep
Title: PCSK9 is required for the disposal of non-acetylated intermediates of the nascent membrane protein BACE1.
Volume: 9
Issue: 9
Pages: 916-22
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Publication
16267225 | J:102728
First Author: Liang X
Year: 2005
Journal: J Neurosci
Title: Deletion of the prostaglandin E2 EP2 receptor reduces oxidative damage and amyloid burden in a model of Alzheimer's disease.
Volume: 25
Issue: 44
Pages: 10180-7
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Publication
22912719 | J:189875
First Author: Koike MA
Year: 2012
Journal: PLoS One
Title: APP knockout mice experience acute mortality as the result of ischemia.
Volume: 7
Issue: 8
Pages: e42665
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Publication
16354928 | J:123534
First Author: Laird FM
Year: 2005
Journal: J Neurosci
Title: BACE1, a major determinant of selective vulnerability of the brain to amyloid-beta amyloidogenesis, is essential for cognitive, emotional, and synaptic functions.
Volume: 25
Issue: 50
Pages: 11693-709
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Publication
23825420 | J:199824
First Author: Bhattacharyya R
Year: 2013
Journal: J Neurosci
Title: Palmitoylation of amyloid precursor protein regulates amyloidogenic processing in lipid rafts.
Volume: 33
Issue: 27
Pages: 11169-83
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Publication
23754390 | J:197977
First Author: Rochin L
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: BACE2 processes PMEL to form the melanosome amyloid matrix in pigment cells.
Volume: 110
Issue: 26
Pages: 10658-63
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Publication
32407295 | J:293959
First Author: Meakin PJ
Year: 2020
Journal: J Clin Invest
Title: Elevated circulating amyloid concentrations in obesity and diabetes promote vascular dysfunction.
Volume: 130
Issue: 8
Pages: 4104-4117
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Publication
20704561 | J:277904
First Author: Davis W Jr
Year: 2010
Journal: Curr Alzheimer Res
Title: The ATP-binding cassette transporter-2 (ABCA2) increases endogenous amyloid precursor protein expression and Aβ fragment generation.
Volume: 7
Issue: 7
Pages: 566-77
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Publication
26414661 | J:243323
First Author: Maesako M
Year: 2015
Journal: PLoS One
Title: High Fat Diet Enhances β-Site Cleavage of Amyloid Precursor Protein (APP) via Promoting β-Site APP Cleaving Enzyme 1/Adaptor Protein 2/Clathrin Complex Formation.
Volume: 10
Issue: 9
Pages: e0131199
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Publication
30120949 | J:270232
 
First Author: Wang M
Year: 2018
Journal: Neurosci Lett
Title: Beta-secretase/BACE1 promotes APP endocytosis and processing in the endosomes and on cell membrane.
Volume: 685
Pages: 63-67
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Publication
26322584 | J:226790
First Author: Willem M
Year: 2015
Journal: Nature
Title: η-Secretase processing of APP inhibits neuronal activity in the hippocampus.
Volume: 526
Issue: 7573
Pages: 443-7
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Publication
18341989 | J:132937
First Author: Wen Y
Year: 2008
Journal: Neuron
Title: Transcriptional regulation of beta-secretase by p25/cdk5 leads to enhanced amyloidogenic processing.
Volume: 57
Issue: 5
Pages: 680-90
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Publication
22836275 | J:186537
First Author: Walker KR
Year: 2012
Journal: J Neurosci
Title: Depletion of GGA1 and GGA3 mediates postinjury elevation of BACE1.
Volume: 32
Issue: 30
Pages: 10423-37
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Publication
15745965 | J:98609
First Author: Lazarov O
Year: 2005
Journal: J Neurosci
Title: Axonal transport, amyloid precursor protein, kinesin-1, and the processing apparatus: revisited.
Volume: 25
Issue: 9
Pages: 2386-95
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Publication
26900752 | J:236654
First Author: Oliverio M
Year: 2016
Journal: Nat Cell Biol
Title: Dicer1-miR-328-Bace1 signalling controls brown adipose tissue differentiation and function.
Volume: 18
Issue: 3
Pages: 328-36
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Publication
24005676 | J:207246
First Author: Deng M
Year: 2013
Journal: J Biol Chem
Title: Increased expression of reticulon 3 in neurons leads to reduced axonal transport of β site amyloid precursor protein-cleaving enzyme 1.
Volume: 288
Issue: 42
Pages: 30236-45
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Publication
22988240 | J:192472
First Author: Hitt B
Year: 2012
Journal: J Biol Chem
Title: β-Site amyloid precursor protein (APP)-cleaving enzyme 1 (BACE1)-deficient mice exhibit a close homolog of L1 (CHL1) loss-of-function phenotype involving axon guidance defects.
Volume: 287
Issue: 46
Pages: 38408-25
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Publication
20092558 | J:158363
First Author: Devi L
Year: 2010
Journal: Eur J Neurosci
Title: Genetic reductions of beta-site amyloid precursor protein-cleaving enzyme 1 and amyloid-beta ameliorate impairment of conditioned taste aversion memory in 5XFAD Alzheimer's disease model mice.
Volume: 31
Issue: 1
Pages: 110-8
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Publication
23335052 | J:197749
First Author: Hu X
Year: 2013
Journal: FASEB J
Title: Reversing hypomyelination in BACE1-null mice with Akt-DD overexpression.
Volume: 27
Issue: 5
Pages: 1868-73
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Publication
29311632 | J:260174
First Author: Meakin PJ
Year: 2018
Journal: Sci Rep
Title: Bace1-dependent amyloid processing regulates hypothalamic leptin sensitivity in obese mice.
Volume: 8
Issue: 1
Pages: 55
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Publication
18385378 | J:133643
First Author: Savonenko AV
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Alteration of BACE1-dependent NRG1/ErbB4 signaling and schizophrenia-like phenotypes in BACE1-null mice.
Volume: 105
Issue: 14
Pages: 5585-90
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Publication
21190943 | J:170564
First Author: Kim DY
Year: 2011
Journal: J Biol Chem
Title: Reduced sodium channel Na(v)1.1 levels in BACE1-null mice.
Volume: 286
Issue: 10
Pages: 8106-16
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Publication
32921309 | J:324398
First Author: Johnson ECB
Year: 2020
Journal: Mol Neurodegener
Title: Behavioral and neural network abnormalities in human APP transgenic mice resemble those of App knock-in mice and are modulated by familial Alzheimer's disease mutations but not by inhibition of BACE1.
Volume: 15
Issue: 1
Pages: 53
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Publication
29979789 | J:263821
First Author: Causevic M
Year: 2018
Journal: PLoS One
Title: BACE1-cleavage of Sez6 and Sez6L is elevated in Niemann-Pick type C disease mouse brains.
Volume: 13
Issue: 7
Pages: e0200344
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Protein Coding Gene
MGP_CAROLIEiJ_G0032148 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0034741 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0034722 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0034649 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0034713 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0034424 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI_C57BL6J_1346542 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C57BL6NJ_G0035234 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CASTEiJ_G0033746 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CBAJ_G0034396 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_DBA2J_G0034555 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_FVBNJ_G0034496 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_LPJ_G0034636 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NODShiLtJ_G0034540 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NZOHlLtJ_G0035255 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PWKPhJ_G0033451 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_WSBEiJ_G0033859 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PahariEiJ_G0015018 | -
Type: protein_coding_gene
Organism: Mus pahari
•
•
•
•
•
Protein Coding Gene
MGP_SPRETEiJ_G0033287 | -
Type: protein_coding_gene
Organism: Mus spretus
•
•
•
•
•
Publication
22049418 | J:177847
First Author: Giusti-Rodríguez P
Year: 2011
Journal: J Neurosci
Title: Synaptic deficits are rescued in the p25/Cdk5 model of neurodegeneration by the reduction of β-secretase (BACE1).
Volume: 31
Issue: 44
Pages: 15751-6
•
•
•
•
•
Publication
21933711 | J:179837
First Author: Devi L
Year: 2012
Journal: Neurobiol Dis
Title: Mitochondrial dysfunction and accumulation of the β-secretase-cleaved C-terminal fragment of APP in Alzheimer's disease transgenic mice.
Volume: 45
Issue: 1
Pages: 417-24
•
•
•
•
•
Publication
11406613 | J:77414
First Author: Roberds SL
Year: 2001
Journal: Hum Mol Genet
Title: BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: implications for Alzheimer's disease therapeutics.
Volume: 10
Issue: 12
Pages: 1317-24
•
•
•
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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