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Search results 101 to 106 out of 106 for Emc6

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0.016s

Type

Details

Score

Protein Domain

IPR029008 | EMC6-like

Type:

Family

Description:

This family consists of several Rab5-interacting proteins (RIP5 or Rab5ip) including ER membrane protein complex subunit 6 (EMC6) and RCAF1. The ras-related GTPase rab5 is rate-limiting for homotypic early endosome fusion. Rab5ip represents a novel rab5 interacting protein that may function on endocytic vesicles as a receptor for rab5-GDP and participate in the activation of rab5 []. EMC6 interacts with Rab5A and BECN1/Beclin 1 and regulates autophagosome formation []. EMC6 is part of the EMC complex, required for efficient folding of proteins in the ER []and for post-translational membrane insertion of tail-anchored (TA) proteins [, ]. RCAF1 acts as an assembly factor for mitochondrial respiratory complexes [].

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Publication

31536960 | J:282679

First Author:	Moutaoufik MT
Year:	2019
Journal:	iScience
Title:	Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis.
Volume:	19

Pages:	1114-1132

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Protein

Q9CQT9

Organism:	Mus musculus/domesticus
Length:	129
Fragment?:	false

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Publication

31263175 | J:280458

First Author:	Xiong L
Year:	2019
Journal:	Cell Death Differ
Title:	ER complex proteins are required for rhodopsin biosynthesis and photoreceptor survival in Drosophila and mice.

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Publication

32459176 | -

First Author:	O'Donnell JP
Year:	2020
Journal:	Elife
Title:	The architecture of EMC reveals a path for membrane protein insertion.
Volume:	9

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Publication

32439656 | -

First Author:	Pleiner T
Year:	2020
Journal:	Science
Title:	Structural basis for membrane insertion by the human ER membrane protein complex.
Volume:	369
Issue:	6502
Pages:	433-436

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