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Search results 501 to 550 out of 550 for Pms1

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0.019s

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Type Details Score
Genotype
Genotype
Symbol: Apc/Apc<+> Pms2/Pms2
Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Publication
9286595 | J:42585
First Author: Mansouri A
Year: 1997
Journal: Dev Dyn
Title: Paired-related murine homeobox gene expressed in the developing sclerotome, kidney, and nervous system.
Volume: 210
Issue: 1
Pages: 53-65
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Publication
16713580 | J:111285
First Author: Yoshioka K
Year: 2006
Journal: Mol Cell
Title: ATR kinase activation mediated by MutSalpha and MutLalpha in response to cytotoxic O6-methylguanine adducts.
Volume: 22
Issue: 4
Pages: 501-10
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Pms2/Pms2
Background: involves: 129S4/SvJaeSor
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Pms2/Pms2<+>
Background: involves: 129S4/SvJaeSor
Zygosity: cn
Has Mutant Allele: true
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Publication
9192668 | J:41499
First Author: Mizuta R
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: RAB22 and RAB163/mouse BRCA2: proteins that specifically interact with the RAD51 protein.
Volume: 94
Issue: 13
Pages: 6927-32
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Publication
10809667 | J:62204
First Author: Kneitz B
Year: 2000
Journal: Genes Dev
Title: MutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female mice.
Volume: 14
Issue: 9
Pages: 1085-97
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Kras/Kras<+> Pms2/Pms2
Background: involves: 129S4/SvJae * 129S4/SvJaeSor
Zygosity: cn
Has Mutant Allele: true
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Publication
7980603 | J:21954
First Author: Horii A
Year: 1994
Journal: Biochem Biophys Res Commun
Title: Cloning, characterization and chromosomal assignment of the human genes homologous to yeast PMS1, a member of mismatch repair genes.
Volume: 204
Issue: 3
Pages: 1257-64
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Publication
9110401 | J:40099
First Author: Prolla TA
Year: 1996
Journal: Semin Cancer Biol
Title: DNA mismatch repair deficient mice in cancer research.
Volume: 7
Issue: 5
Pages: 241-7
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Publication
3304141 | -
 
First Author: Modrich P
Year: 1987
Journal: Annu Rev Biochem
Title: DNA mismatch correction.
Volume: 56
Pages: 435-66
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Publication
8264608 | -
First Author: Prolla TA
Year: 1994
Journal: Mol Cell Biol
Title: Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene.
Volume: 14
Issue: 1
Pages: 407-15
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Publication
8145827 | J:17196
First Author: Bronner CE
Year: 1994
Journal: Nature
Title: Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer.
Volume: 368
Issue: 6468
Pages: 258-61
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Publication
12052432 | -
First Author: Bernstein C
Year: 2002
Journal: Mutat Res
Title: DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: fail-safe protection against carcinogenesis.
Volume: 511
Issue: 2
Pages: 145-78
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Protein Domain
IPR014762 | DNA_mismatch_repair_CS
Type: Conserved_site
Description: Mismatch repair contributes to the overall fidelity of DNA replication []. It involves the correction of mismatched base pairs that have been missed by the proofreading element of the DNA polymerase complex. The sequence of some proteins involved in mismatch repair in different organisms have been found to be evolutionarily related. These proteins include:Escherichia coli and Salmonella typhimurium mutL protein []. MutL is required for dam-dependent methyl-directed DNA repair.Streptococcus pneumoniae hexB protein []. The Hex system is nick directed.Yeast proteins PMS1 and MLH1 [].Human protein MLH1 []which is involved in a form of familial hereditary nonpolyposis colon cancer (HNPCC).This entry represents a perfectly conserved heptapeptide which is located in the N-terminal sectionof these proteins.
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Protein Domain
IPR020667 | DNA_mismatch_repair_MutL
Type: Family
Description: Mismatch repair is one of five major DNA repair pathways, the others being homologous recombination repair, non-homologous end joining, nucleotide excision repair, and base excision repair. The mismatch repair system recognises and repairs mispaired or unpaired nucleotides that result from errors in DNA replication. Many proteins involved in the different repair processes also play a role in apoptosis when DNA damage is excessive, thereby helping to prevent carcinogenesis []. The mismatch repair protein, Mlh1 (mutL homologue 1), has a dual role in DNA repair and apoptosis. Mlh1 acts as a heterodimer in conjunction with Pms2, Pms1 (post-meiotic segregation 1 and 2) or Mlh3 (MutL homologue 3), which function as adaptor proteins that link Msh (MutS homologue) heterodimers to the DNA repair machinery, resulting in excision and repair of the mispaired base [].This entry represents the mismatch repair protein MutL.
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Publication
12091911 | J:78200
First Author: Lipkin SM
Year: 2002
Journal: Nat Genet
Title: Meiotic arrest and aneuploidy in MLH3-deficient mice.
Volume: 31
Issue: 4
Pages: 385-90
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Publication
10615123 | J:59324
First Author: Lipkin SM
Year: 2000
Journal: Nat Genet
Title: MLH3: a DNA mismatch repair gene associated with mammalian microsatellite instability.
Volume: 24
Issue: 1
Pages: 27-35
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Publication
14570593 | J:87893
First Author: Jonckheere N
Year: 2004
Journal: Biochem J
Title: Transcriptional activation of the murine Muc5ac mucin gene in epithelial cancer cells by TGF-beta/Smad4 signalling pathway is potentiated by Sp1.
Volume: 377
Issue: Pt 3
Pages: 797-808
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Publication
23920106 | J:202864
First Author: Keil KP
Year: 2013
Journal: Gene Expr Patterns
Title: Catalog of mRNA expression patterns for DNA methylating and demethylating genes in developing mouse lower urinary tract.
Volume: 13
Issue: 8
Pages: 413-24
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Publication
21062905 | J:220439
First Author: McLachlan S
Year: 2011
Journal: Physiol Genomics
Title: In silico QTL mapping of basal liver iron levels in inbred mouse strains.
Volume: 43
Issue: 3
Pages: 136-47
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Publication
12222686 | -
First Author: Drotschmann K
Year: 2002
Journal: Biol Chem
Title: DNA binding properties of the yeast Msh2-Msh6 and Mlh1-Pms1 heterodimers.
Volume: 383
Issue: 6
Pages: 969-75
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Protein
Q8R0Y8
Organism: Mus musculus/domesticus
Length: 318  
Fragment?: false
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Protein
Q9JK91
Organism: Mus musculus/domesticus
Length: 760  
Fragment?: false
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Protein
E9QLM4
Organism: Mus musculus/domesticus
Length: 461  
Fragment?: false
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Protein
Q8CAP8
Organism: Mus musculus/domesticus
Length: 653  
Fragment?: false
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Protein
Q8R407
Organism: Mus musculus/domesticus
Length: 338  
Fragment?: true
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Protein
Q8BZC3
Organism: Mus musculus/domesticus
Length: 434  
Fragment?: true
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Protein
Q8VDI4
Organism: Mus musculus/domesticus
Length: 760  
Fragment?: false
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Protein
Q3UJP0
Organism: Mus musculus/domesticus
Length: 859  
Fragment?: false
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Protein
A0A1Y7VMP7
Organism: Mus musculus/domesticus
Length: 1443  
Fragment?: false
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Protein
Q3V1X3
Organism: Mus musculus/domesticus
Length: 1411  
Fragment?: false
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Protein
B9EJ22
Organism: Mus musculus/domesticus
Length: 859  
Fragment?: false
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Protein
Q68FG1
Organism: Mus musculus/domesticus
Length: 1411  
Fragment?: false
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Protein
Q8K119
Organism: Mus musculus/domesticus
Length: 917  
Fragment?: false
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Protein
Q3US89
Organism: Mus musculus/domesticus
Length: 669  
Fragment?: true
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
15226823 | J:93300
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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