This entry includes Ost5 from budding yeasts and TMEM258 from animals. Ost5 is an essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyses the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains []. TMEM258 is a component of the oligosaccharyltransferase (OST) complex controlling ER stress and intestinal inflammation [].
