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Search results 101 to 200 out of 213 for Tef

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Type Details Score
Publication
9226367 | J:41656
First Author: Brinkmeier ML
Year: 1997
Journal: Genomics
Title: Localization of somatostatin receptor genes on mouse chromosomes 2, 11, 12, 15, and 17: correlation with growth QTLs.
Volume: 43
Issue: 1
Pages: 9-14
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Author
Quax TEF
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Publication
15306695 | J:91835
First Author: Kaput J
Year: 2004
Journal: Physiol Genomics
Title: Identification of genes contributing to the obese yellow Avy phenotype: caloric restriction, genotype, diet x genotype interactions.
Volume: 18
Issue: 3
Pages: 316-24
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Publication
23375831 | J:237827
First Author: Gineste C
Year: 2013
Journal: Neuromuscul Disord
Title: In vivo and in vitro investigations of heterozygous nebulin knock-out mice disclose a mild skeletal muscle phenotype.
Volume: 23
Issue: 4
Pages: 357-69
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Publication
8827514 | J:34178
First Author: Welch CL
Year: 1996
Journal: J Lipid Res
Title: Genetic regulation of cholesterol homeostasis: chromosomal organization of candidate genes.
Volume: 37
Issue: 7
Pages: 1406-21
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:157064
     
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
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Publication
20412781 | J:140465
First Author: Guo G
Year: 2010
Journal: Dev Cell
Title: Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Volume: 18
Issue: 4
Pages: 675-85
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Gene
30674 | tefa
Type: gene
Organism: zebrafish
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Gene
553686 | tefb
Type: gene
Organism: zebrafish
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Publication
9671946 | J:48579
First Author: Jacquemin P
Year: 1998
Journal: Dev Dyn
Title: Differential expression of the TEF family of transcription factors in the murine placenta and during differentiation of primary human trophoblasts in vitro.
Volume: 212
Issue: 3
Pages: 423-36
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Publication
8639829 | -
First Author: Hunger SP
Year: 1996
Journal: Blood
Title: The proto-oncogene HLF and the related basic leucine zipper protein TEF display highly similar DNA-binding and transcriptional regulatory properties.
Volume: 87
Issue: 11
Pages: 4607-17
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Publication
30884174 | -
First Author: Braun F
Year: 2019
Journal: Microbiologyopen
Title: Cyclic nucleotides in archaea: Cyclic di-AMP in the archaeon Haloferax volcanii and its putative role.
Volume: 8
Issue: 9
Pages: e00829
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Allele
Tef<em1Smoc> | MGI:7292721
Name: thyrotroph embryonic factor; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6355244 | C57BL/6J-Tef<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Publication
10518497 | -
First Author: Vaudin P
Year: 1999
Journal: Development
Title: TONDU (TDU), a novel human protein related to the product of vestigial (vg) gene of Drosophila melanogaster interacts with vertebrate TEF factors and substitutes for Vg function in wing formation.
Volume: 126
Issue: 21
Pages: 4807-16
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Publication
8617210 | -
First Author: Fonjallaz P
Year: 1996
Journal: EMBO J
Title: The two PAR leucine zipper proteins, TEF and DBP, display similar circadian and tissue-specific expression, but have different target promoter preferences.
Volume: 15
Issue: 2
Pages: 351-62
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Publication
1386162 | J:18114
First Author: Inaba T
Year: 1992
Journal: Science
Title: Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia.
Volume: 257
Issue: 5069
Pages: 531-4
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Publication
7984425 | -
First Author: Burch JB
Year: 1994
Journal: Nucleic Acids Res
Title: Alternative promoter usage and splicing options result in the differential expression of mRNAs encoding four isoforms of chicken VBP, a member of the PAR subfamily of bZIP transcription factors.
Volume: 22
Issue: 22
Pages: 4733-41
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Publication
1922023 | -
First Author: Iyer SV
Year: 1991
Journal: Mol Cell Biol
Title: Chicken vitellogenin gene-binding protein, a leucine zipper transcription factor that binds to an important control element in the chicken vitellogenin II promoter, is related to rat DBP.
Volume: 11
Issue: 10
Pages: 4863-75
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Publication
17057225 | -
First Author: Benito A
Year: 2006
Journal: J Biol Chem
Title: A novel role for proline- and acid-rich basic region leucine zipper (PAR bZIP) proteins in the transcriptional regulation of a BH3-only proapoptotic gene.
Volume: 281
Issue: 50
Pages: 38351-7
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Protein Domain
IPR029832 | TEF/VBP
Type: Family
Description: Thyrotroph embryonic factor (TEF) belongs to the PAR (Proline and Acidic amino acid-Rich basic leucine ZIPper) transcription factor family, which consists of HLF, DBP and TEF proteins []. TEF may bind DNA specifically as a homodimer or as a heterodimer with other PAR factors. It binds to the consensus sequence 5'-GTTACGTAAT-3' []. TEF is involved in the regulation of apoptotic proteins [, ]. In chicken it is known as VBP, which binds to and transactivates the vitellogenin II (VTG2) promoter [, ].
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Publication
8786133 | J:33853
First Author: Shutler G
Year: 1996
Journal: Genomics
Title: Genomic structure of the human D-site binding protein (DBP) gene.
Volume: 34
Issue: 3
Pages: 334-9
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Protein Domain
IPR006627 | TDU_repeat
Type: Repeat
Description: The mammalian TEF and the Drosophila scalloped genes belong to a conserved family of transcriptional factors that possesses aTEA/ATTS DNA-binding domain. Transcriptional activation by these proteins likely requires interactions with specific coactivators. InDrosophila, Scalloped (Sd) interacts with Vestigial (Vg) to form a complex, which binds DNA through the Sd TEA/ATTS domain.The Sd-Vg heterodimer is a key regulator of wing development, which directly controls several target genes and is able to induce wingoutgrowth when ectopically expressed. The human protein, TONDU, contains a short domain homologous to the domain of Vg required for interaction withSd. TONDU specifically interacts with a domain conserved in all the mammalian TEF factors [].
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Publication
1297647 | -
 
First Author: Wuarin J
Year: 1992
Journal: J Cell Sci Suppl
Title: The role of the transcriptional activator protein DBP in circadian liver gene expression.
Volume: 16
Pages: 123-7
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Protein Domain
IPR029830 | DBP
Type: Family
Description: D site-binding protein (DBP) belongs to the PAR (Proline and Acidic amino acid-Rich basic leucine ZIPper) transcription factor family, which consists of HLF, DBP and TEF proteins []. DBP may bind DNA specifically as a homodimer or as a heterodimer with other PAR factors. It accumulates in the liver according to a very strong circadian rhythm regulated by hormones [].
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Protein
Q80V24
Organism: Mus musculus/domesticus
Length: 287  
Fragment?: false
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Protein
Q3TQI9
Organism: Mus musculus/domesticus
Length: 281  
Fragment?: false
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Protein
Q3TSJ2
Organism: Mus musculus/domesticus
Length: 201  
Fragment?: false
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Protein
D3Z130
Organism: Mus musculus/domesticus
Length: 230  
Fragment?: true
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Protein
E9Q3N8
Organism: Mus musculus/domesticus
Length: 70  
Fragment?: true
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Protein
E9Q331
Organism: Mus musculus/domesticus
Length: 106  
Fragment?: true
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HT Experiment
E-TABM-726 | Transcription profiling of liver from wild type, Rev knock out and Rev-erb-alpha transgenic mice to identify target genes of PAR bZip
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Protein
P85442
Organism: Mus musculus/domesticus
Length: 326  
Fragment?: false
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Protein
A0A2I3BPM3
Organism: Mus musculus/domesticus
Length: 270  
Fragment?: false
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Protein
E9Q1Y1
Organism: Mus musculus/domesticus
Length: 325  
Fragment?: false
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Publication
20519628 | -
First Author: Hirose K
Year: 2010
Journal: Blood
Title: Aberrant induction of LMO2 by the E2A-HLF chimeric transcription factor and its implication in leukemogenesis of B-precursor ALL with t(17;19).
Volume: 116
Issue: 6
Pages: 962-70
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Publication
23415677 | -
First Author: Waters KM
Year: 2013
Journal: Toxicol Appl Pharmacol
Title: Hepatic leukemia factor promotes resistance to cell death: implications for therapeutics and chronotherapy.
Volume: 268
Issue: 2
Pages: 141-8
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Protein Domain
IPR029829 | HLF
Type: Family
Description: Hepatic leukemia factor (HLF) belongs to the PAR (Proline and Acidic amino acid-Rich basic leucine ZIPper) transcription factor family, which consists of HLF, DBP and TEF proteins []. HLF binds DNA specifically as a homodimer or as a heterodimer with other PAR factors. It binds to the consensus sequence 5'-GTTACGTAAT-3' []. In B-precursor acute lymphoblastic leukemia (ALL), it fuses to the N terminus of the E2A protein [], and this chimeric protein promotes cell survival of t(17;19)-ALL cells by aberrantly up-regulating the expression of hematopoiesis transcription regulator LMO2 []. HLF regulates a complex multi-gene transcriptional program that involves upregulation of anti-apoptotic genes and downregulation of pro-apoptotic genes [].
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Publication
10934189 | J:65012
First Author: Belandia B
Year: 2000
Journal: J Biol Chem
Title: Functional interaction between the p160 coactivator proteins and the transcriptional enhancer factor family of transcription factors.
Volume: 275
Issue: 40
Pages: 30801-5
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Protein
Q9JLC6
Organism: Mus musculus/domesticus
Length: 301  
Fragment?: false
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Protein
Q3V3B6
Organism: Mus musculus/domesticus
Length: 285  
Fragment?: false
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Publication
12376544 | J:80338
First Author: Maeda T
Year: 2002
Journal: J Biol Chem
Title: Mammalian vestigial-like 2, a cofactor of TEF-1 and MEF2 transcription factors that promotes skeletal muscle differentiation.
Volume: 277
Issue: 50
Pages: 48889-98
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Protein
Q8BGW8
Organism: Mus musculus/domesticus
Length: 322  
Fragment?: false
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Protein
Q99NC0
Organism: Mus musculus/domesticus
Length: 307  
Fragment?: false
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Protein
A3KN78
Organism: Mus musculus/domesticus
Length: 202  
Fragment?: false
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Protein
A2AFK0
Organism: Mus musculus/domesticus
Length: 150  
Fragment?: true
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Protein
Q3UK89
Organism: Mus musculus/domesticus
Length: 307  
Fragment?: false
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Protein
A6H6P3
Organism: Mus musculus/domesticus
Length: 307  
Fragment?: false
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Protein
B7ZN07
Organism: Mus musculus/domesticus
Length: 307  
Fragment?: false
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Publication
22632831 | J:247423
First Author: Pobbati AV
Year: 2012
Journal: Structure
Title: Structural and functional similarity between the Vgll1-TEAD and the YAP-TEAD complexes.
Volume: 20
Issue: 7
Pages: 1135-40
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Publication
8626521 | -
First Author: Farrance IK
Year: 1996
Journal: J Biol Chem
Title: The role of transcription enhancer factor-1 (TEF-1) related proteins in the formation of M-CAT binding complexes in muscle and non-muscle tissues.
Volume: 271
Issue: 14
Pages: 8266-74
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Publication
17652751 | -
First Author: Appukuttan B
Year: 2007
Journal: Invest Ophthalmol Vis Sci
Title: Identification of novel alternatively spliced isoforms of RTEF-1 within human ocular vascular endothelial cells and murine retina.
Volume: 48
Issue: 8
Pages: 3775-82
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Publication
15073166 | -
First Author: Shie JL
Year: 2004
Journal: J Biol Chem
Title: RTEF-1, a novel transcriptional stimulator of vascular endothelial growth factor in hypoxic endothelial cells.
Volume: 279
Issue: 24
Pages: 25010-6
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Protein Domain
IPR027253 | TEF-5
Type: Family
Description: The TEAD family (also known as TEF family) transcription factors play a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumour suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. TEAD transcription factors act by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction [, ].Four TEAD genes exist in mammals (TEAD 1 to 4). TEAD3 (transcriptional enhancer factor TEF-5) has a role in placental development [].
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Protein Domain
IPR027255 | TEF-3
Type: Family
Description: The TEAD family (also known as the TEF family) transcription factors play a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. TEAD transcription factors act by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction [, ].Four TEAD genes exist in mammals (TEAD 1 to 4). TEAD4 protein (also known as TEF-3) was reported to regulate muscle-specific genes in cardiac and smooth muscle cells []. Alternatively spliced transcripts for TEAD4 have been identified in human retinal vascular endothelial cells []. TEAD4 protein has been shown to enhance VEGF gene expression in bovine aortic endothelial cells [].
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Protein Domain
IPR011520 | Vg_fam
Type: Family
Description: The mammalian TEF and the Drosophila scalloped genes belong to a conserved family of transcriptional factors that possesses a TEA/ATTS DNA-binding domain. Transcriptional activation by these proteins likely requires interactions with specific coactivators.In Drosophila, Vestigial (Vg) has a short 25 aa motif necessary and sufficient to interact with Scalloped (Sd) to form a complex. This motif is also present in four mammalian proteins, which are named Vestigial-like proteins (Vgl1-4) [, , ].In Drosophila, the Vg-Sd complex binds DNA through the Sd TEA/ATTS domain. The Sd-Vg heterodimer is a key regulator of wing development, which directly controls several target genes and is able to induce wing outgrowth when ectopically expressed. This short conserved region is needed for interaction with Sd [].Mammalian Vgl-1 may promote cancer progression []. Vgl-2 interacts with TEF-1and MEF2 to promote skeletal muscle differentiation []. Vgl-4, is the only member of the Vestigial-like family expressed in the heart [].
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Publication
8702974 | J:35437
First Author: Jacquemin P
Year: 1996
Journal: J Biol Chem
Title: A novel family of developmentally regulated mammalian transcription factors containing the TEA/ATTS DNA binding domain.
Volume: 271
Issue: 36
Pages: 21775-85
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Publication
9148898 | J:40499
First Author: Jacquemin P
Year: 1997
Journal: J Biol Chem
Title: Human TEF-5 is preferentially expressed in placenta and binds to multiple functional elements of the human chorionic somatomammotropin-B gene enhancer.
Volume: 272
Issue: 20
Pages: 12928-37
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Publication
17522155 | J:122531
First Author: Que J
Year: 2007
Journal: Development
Title: Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endoderm.
Volume: 134
Issue: 13
Pages: 2521-31
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Publication
21129973 | J:171851
First Author: Masumoto KH
Year: 2010
Journal: Curr Biol
Title: Acute induction of Eya3 by late-night light stimulation triggers TSHβ expression in photoperiodism.
Volume: 20
Issue: 24
Pages: 2199-206
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Publication
14762206 | J:87788
First Author: Günther S
Year: 2004
Journal: Nucleic Acids Res
Title: VITO-1 is an essential cofactor of TEF1-dependent muscle-specific gene regulation.
Volume: 32
Issue: 2
Pages: 791-802
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Publication
16916379 | J:111617
First Author: Que J
Year: 2006
Journal: Differentiation
Title: Morphogenesis of the trachea and esophagus: current players and new roles for noggin and Bmps.
Volume: 74
Issue: 7
Pages: 422-37
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Publication
21540178 | J:174807
First Author: Jin Y
Year: 2011
Journal: J Biol Chem
Title: RTEF-1, an upstream gene of hypoxia-inducible factor-1α, accelerates recovery from ischemia.
Volume: 286
Issue: 25
Pages: 22699-705
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Publication
18579750 | -
First Author: Zhao B
Year: 2008
Journal: Genes Dev
Title: TEAD mediates YAP-dependent gene induction and growth control.
Volume: 22
Issue: 14
Pages: 1962-71
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Publication
19324877 | -
First Author: Zhang H
Year: 2009
Journal: J Biol Chem
Title: TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition.
Volume: 284
Issue: 20
Pages: 13355-62
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Publication
10023025 | J:53226
First Author: Hitzler JK
Year: 1999
Journal: Brain Res
Title: Expression patterns of the hepatic leukemia factor gene in the nervous system of developing and adult mice.
Volume: 820
Issue: 1-2
Pages: 1-11
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•
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Publication
19082487 | J:156982
First Author: Lee S
Year: 2009
Journal: Int J Oncol
Title: Profiling of transcripts and proteins modulated by K-ras oncogene in the lung tissues of K-ras transgenic mice by omics approaches.
Volume: 34
Issue: 1
Pages: 161-72
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Publication
20182749 | J:161872
First Author: Hajduk P
Year: 2010
Journal: Pediatr Surg Int
Title: Mesenchymal expression of Tbx4 gene is not altered in Adriamycin mouse model.
Volume: 26
Issue: 4
Pages: 407-11
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Protein
H3BKN8
Organism: Mus musculus/domesticus
Length: 142  
Fragment?: true
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Publication
15140898 | J:284977
First Author: Chen HH
Year: 2004
Journal: J Biol Chem
Title: Vgl-4, a novel member of the vestigial-like family of transcription cofactors, regulates alpha1-adrenergic activation of gene expression in cardiac myocytes.
Volume: 279
Issue: 29
Pages: 30800-6
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Protein
Q60925
Organism: Mus musculus/domesticus
Length: 325  
Fragment?: false
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Protein
Q8BW74
Organism: Mus musculus/domesticus
Length: 295  
Fragment?: false
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•
•
•
Protein
Q3USN7
Organism: Mus musculus/domesticus
Length: 325  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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