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Search results 101 to 135 out of 135 for Marf1

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Type Details Score
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
HT Experiment
Series Id: GSE31985
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Allele  
Name: meiosis regulator and mRNA stability 1; mutation 1, The Jackson Laboratory Reproductive Genomics Program
Allele Type: Chemically induced (ENU)
Protein Domain
Type: Domain
Description: This entry represents the RNA recognition motif 1 (RRM1) of MARF1 (also known as Limkain-b1).MARF1 was first identified as a novel peroxisomal autoantigen that co-localizes with a subset of cytoplasmic microbodies marked by ABCD3 []. Later, it was found to be an essential protein for controlling meiosis and retrotransposon surveillance in mouse oocytes. It may function both as an adaptor to recruit specific RNA targets and an effector to catalyse the specific cleavages of target RNAs []. MARF1 contains an N-terminal NYN domain, two central RRMs, and C-terminal OST-HTH/LOTUS domains [, ].
Protein Domain
Type: Domain
Description: This entry represents the RNA recognition motif 2 (RRM2) of MARF1 (also known as Limkain-b1).MARF1 was first identified as a novel peroxisomal autoantigen that co-localizes with a subset of cytoplasmic microbodies marked by ABCD3 []. Later, it was found to be an essential protein for controlling meiosis and retrotransposon surveillance in mouse oocytes. It may function both as an adaptor to recruit specific RNA targets and an effector to catalyse the specific cleavages of target RNAs []. MARF1 contains an N-terminal NYN domain, two central RRMs, and C-terminal OST-HTH/LOTUS domains [, ].
Protein
Organism: Mus musculus/domesticus
Length: 427  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 265  
Fragment?: true
Publication
First Author: Gudkova D
Year: 2012
Journal: FEBS Lett
Title: EDC4 interacts with and regulates the dephospho-CoA kinase activity of CoA synthase.
Volume: 586
Issue: 20
Pages: 3590-5
Publication
First Author: Rahman H
Year: 2014
Journal: Int J Mol Sci
Title: Crosstalk between Edc4 and mammalian target of rapamycin complex 1 (mTORC1) signaling in mRNA decapping.
Volume: 15
Issue: 12
Pages: 23179-95
Publication    
First Author: Brothers WR
Year: 2020
Journal: Elife
Title: A non-canonical role for the EDC4 decapping factor in regulating MARF1-mediated mRNA decay.
Volume: 9
Publication
First Author: Seto E
Year: 2015
Journal: PLoS One
Title: The Assembly of EDC4 and Dcp1a into Processing Bodies Is Critical for the Translational Regulation of IL-6.
Volume: 10
Issue: 5
Pages: e0123223
Publication
First Author: Goeres DC
Year: 2007
Journal: Plant Cell
Title: Components of the Arabidopsis mRNA decapping complex are required for early seedling development.
Volume: 19
Issue: 5
Pages: 1549-64
Protein Domain
Type: Family
Description: Ge-1, also known as EDC4 (enhancer of mRNA-decapping protein 4), is a regulator of mRNA decapping to function in the mRNA P-bodies within the cytoplasm. It has been shown to interact with mTORC1 [], coenzyme A synthase []and MARF1 []. It is also involved in the regulation of immune system [].This entry also includes EDC4 homologues from fungi and plants [].
Publication
First Author: Bloch DB
Year: 2014
Journal: PLoS One
Title: LMKB/MARF1 localizes to mRNA processing bodies, interacts with Ge-1, and regulates IFI44L gene expression.
Volume: 9
Issue: 4
Pages: e94784
Protein Domain
Type: Domain
Description: This entry represents the first and second LOTUS domains of MARF1. This domain provides RNA-binding properties to this protein, acting as an adapter to recruit targets for the effector domain NYN at the N-terminal (RNase activity) [].Meiosis regulator and mRNA stability factor 1 (also known as meiosis arrest female protein 1, MARF1, or Limkain-b1) was first identified as a novel peroxisomal autoantigen that co-localizes with a subset of cytoplasmic microbodies marked by ABCD3 []. Later, it was found that it is an essential regulator of oogenesis required for female meiotic progression and retrotransposon surveillance, therefore, involved in the maintenance of genomic integrity. It acts as a RNAse that efficiently cleaves ssRNAs and down-regulates RNA transcripts, either at transcriptional of post-transcriptional level [, ]. It may function both as an adaptor to recruit specific RNA targets and an effector to catalyse the specific cleavages of target RNAs. MARF1 consists of three major domains, the N-terminal NYN domain, two RNA recognition motifs (RRMs) and a C-terminal repeat of LOTUS (also known as OST-HTH) domains.
Protein
Organism: Mus musculus/domesticus
Length: 1318  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1406  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1406  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1390  
Fragment?: false