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Search results 1001 to 1066 out of 1066 for Apob

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Type Details Score
Protein
Q99020
Organism: Mus musculus/domesticus
Length: 285  
Fragment?: false
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Protein
Q80XR6
Organism: Mus musculus/domesticus
Length: 311  
Fragment?: false
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Protein
Q3TMZ8
Organism: Mus musculus/domesticus
Length: 325  
Fragment?: false
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Protein
G3UYA2
Organism: Mus musculus/domesticus
Length: 144  
Fragment?: false
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Protein
G3UW39
Organism: Mus musculus/domesticus
Length: 525  
Fragment?: false
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Protein
Q9D6G1
Organism: Mus musculus/domesticus
Length: 276  
Fragment?: false
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Protein
Q3UUA6
Organism: Mus musculus/domesticus
Length: 150  
Fragment?: false
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Protein
Q20BD0
Organism: Mus musculus/domesticus
Length: 332  
Fragment?: false
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Protein
Q544Z3
Organism: Mus musculus/domesticus
Length: 285  
Fragment?: false
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Publication
8428902 | -
First Author: Moore JT
Year: 1993
Journal: J Biol Chem
Title: T4-phage deoxycytidylate deaminase is a metalloprotein containing two zinc atoms per subunit.
Volume: 268
Issue: 4
Pages: 2288-91
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Publication
25723530 | -
First Author: Kim G
Year: 2015
Journal: PLoS Genet
Title: Region-specific activation of oskar mRNA translation by inhibition of Bruno-mediated repression.
Volume: 11
Issue: 2
Pages: e1004992
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Protein Domain
IPR034196 | CELF1/2_RRM1
Type: Domain
Description: The human CELF family has six members, which can be divided into two subfamilies based on their phylogeny: CELF1-2 and CELF3-6. This entry represents the RNA recognition motif 1 (RRM1) of CELF-1 and CELF-2 protein. CELF-1 and CELF-2 belong to the CELF (CUGBP and ETR-3 Like Factor)/Bruno-like protein family, whose members play important roles in the regulation of alternative splicing and translation. CELF-1 and CELF-2 share sequence similarity to the Drosophila Bruno protein and binds to the Bruno response elements (cis-acting sequences in the 3'-untranslated region (UTR) ofoskar mRNA) [].The human CELF-1 (also known as CUG-BP or BRUNOL-2) binds to RNA substrates and recruits PARN deadenylase []. It preferentially targets UGU-rich mRNA elements []. CELF-1 has been implicated in onset of type 1 myotonic dystrophy (DM1), a neuromuscular disease associated with an unstable CUG triplet expansion in the 3'-UTR (3'-untranslated region) of the DMPK (myotonic dystrophy protein kinase) gene [, ]. CELF-1 contain three highly conserved RNA recognition motifs (RRMs): two consecutive RRMs (RRM1 and RRM2) situated in the N-terminal region followed by a linker region and the third RRM (RRM3) close to the C terminus of the protein. The Xenopus homologue of CELF-1 is EDEN-BP (embryo deadenylation element-binding protein), which mediates sequence-specific deadenylation of Eg5 mRNA. It binds specifically to the EDEN motif in the 3'-untranslated regions of maternal mRNAs and targets these mRNAs for deadenylation and translational repression []. The two N-terminal RRMs of EDEN-BP are necessary for the interaction with EDEN as well as a part of the linker region (between RRM2 and RRM3). Oligomerization of EDEN-BP is required for specific mRNA deadenylation and binding []. CELF-2 (also known as CUGBP2 or ETR-3) shares high sequence identity with CELF-1, but shows different binding specificity; it binds preferentially to sequences with UG repeats and UGUU motifs. It also binds to the 3'-UTR of cyclooxygenase-2 messages, affecting both translation and mRNA stability, and binds to apoB mRNA, regulating its C to U editing []. CELF-2 also contains three highly conserved RRMs. It binds to RNA via the first two RRMs, which are also important for localization in the cytoplasm. The splicing activation or repression activity of CELF-2 on some specific substrates is mediated by RRM1/RRM2. Both, RRM1 and RRM2 of CELF-2, can activate cardiac troponin T (cTNT) exon 5 inclusion. In addition, CELF-2 possesses a typical arginine and lysine-rich nuclear localization signal (NLS) in the C terminus, within RRM3 [].Proteins containing this motif also include Drosophila melanogaster Bruno protein, which plays a central role in regulation ofOskar (Osk) expression in flies. It mediates repression by binding to regulatory Bruno response elements (BREs) in the Osk mRNA 3' UTR []. The full-length Bruno protein contains three RRMs, two located in the N-terminal half of the protein and the third near the C terminus, separated by a linker region.
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Publication
8824235 | J:36051
First Author: Nakamuta M
Year: 1996
Journal: J Biol Chem
Title: Complete phenotypic characterization of apobec-1 knockout mice with a wild-type genetic background and a human apolipoprotein B transgenic background, and restoration of apolipoprotein B mRNA editing by somatic gene transfer of Apobec-1.
Volume: 271
Issue: 42
Pages: 25981-8
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Publication
- | J:14305
 
First Author: Klett C
Year: 1991
Journal: Mouse Genome
Title: Mapping of Nmyc-1 to mouse Chromosome 12, band A3/B.
Volume: 89
Pages: 275
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Publication
31541031 | J:286957
 
First Author: Graf C
Year: 2019
Journal: Sci Immunol
Title: Myeloid cell-synthesized coagulation factor X dampens antitumor immunity.
Volume: 4
Issue: 39
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Publication
22864055 | J:189668
First Author: Devarajan A
Year: 2012
Journal: Mol Genet Metab
Title: Macrophage paraoxonase 2 regulates calcium homeostasis and cell survival under endoplasmic reticulum stress conditions and is sufficient to prevent the development of aggravated atherosclerosis in paraoxonase 2 deficiency/apoE-/- mice on a Western diet.
Volume: 107
Issue: 3
Pages: 416-27
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Publication
21361875 | J:172089
First Author: Bourquard N
Year: 2011
Journal: Biochem J
Title: Impaired hepatic insulin signalling in PON2-deficient mice: a novel role for the PON2/apoE axis on the macrophage inflammatory response.
Volume: 436
Issue: 1
Pages: 91-100
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Publication
17122353 | J:309879
First Author: Stoltz DA
Year: 2007
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Paraoxonase-2 deficiency enhances Pseudomonas aeruginosa quorum sensing in murine tracheal epithelia.
Volume: 292
Issue: 4
Pages: L852-60
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Publication
25627690 | J:220019
First Author: Schwarzer C
Year: 2015
Journal: J Biol Chem
Title: Paraoxonase 2 serves a proapopotic function in mouse and human cells in response to the Pseudomonas aeruginosa quorum-sensing molecule N-(3-Oxododecanoyl)-homoserine lactone.
Volume: 290
Issue: 11
Pages: 7247-58
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Protein
Q9Z0H4
Organism: Mus musculus/domesticus
Length: 508  
Fragment?: false
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Protein
S4R2U7
Organism: Mus musculus/domesticus
Length: 460  
Fragment?: false
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Protein
A0A0R4J2B0
Organism: Mus musculus/domesticus
Length: 440  
Fragment?: false
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Protein
E9QA47
Organism: Mus musculus/domesticus
Length: 478  
Fragment?: false
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Protein
V9GX43
Organism: Mus musculus/domesticus
Length: 443  
Fragment?: true
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Protein
S4R1S7
Organism: Mus musculus/domesticus
Length: 472  
Fragment?: false
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Protein
Q8K2D6
Organism: Mus musculus/domesticus
Length: 178  
Fragment?: false
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Protein
S4R2S7
Organism: Mus musculus/domesticus
Length: 276  
Fragment?: true
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Protein
S4R2J2
Organism: Mus musculus/domesticus
Length: 92  
Fragment?: true
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Protein
S4R2L5
Organism: Mus musculus/domesticus
Length: 134  
Fragment?: true
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Protein
G3X908
Organism: Mus musculus/domesticus
Length: 184  
Fragment?: false
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Publication
22653878 | J:188071
First Author: Cheng X
Year: 2012
Journal: J Pharmacol Exp Ther
Title: Hormonal and chemical regulation of paraoxonases in mice.
Volume: 342
Issue: 3
Pages: 688-95
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Publication
9475163 | J:50700
First Author: McNally EM
Year: 1998
Journal: FEBS Lett
Title: Human epsilon-sarcoglycan is highly related to alpha-sarcoglycan (adhalin), the limb girdle muscular dystrophy 2D gene.
Volume: 422
Issue: 1
Pages: 27-32
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Publication
12840045 | J:84436
First Author: Ono R
Year: 2003
Journal: Genome Res
Title: Identification of a large novel imprinted gene cluster on mouse proximal chromosome 6.
Volume: 13
Issue: 7
Pages: 1696-705
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Publication
8661009 | J:32894
First Author: Primo-Parmo SL
Year: 1996
Journal: Genomics
Title: The human serum paraoxonase/arylesterase gene (PON1) is one member of a multigene family.
Volume: 33
Issue: 3
Pages: 498-507
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Publication
18480470 | J:139777
First Author: Monk D
Year: 2008
Journal: Genome Res
Title: Comparative analysis of human chromosome 7q21 and mouse proximal chromosome 6 reveals a placental-specific imprinted gene, TFPI2/Tfpi2, which requires EHMT2 and EED for allelic-silencing.
Volume: 18
Issue: 8
Pages: 1270-81
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Publication
26692333 | J:233169
First Author: Osorio FG
Year: 2016
Journal: Nat Med
Title: Loss of the proteostasis factor AIRAPL causes myeloid transformation by deregulating IGF-1 signaling.
Volume: 22
Issue: 1
Pages: 91-6
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Publication
31073040 | J:274568
 
First Author: Choi JH
Year: 2019
Journal: Science
Title: LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.
Volume: 364
Issue: 6440
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Publication
16341224 | J:106134
First Author: Ono R
Year: 2006
Journal: Nat Genet
Title: Deletion of Peg10, an imprinted gene acquired from a retrotransposon, causes early embryonic lethality.
Volume: 38
Issue: 1
Pages: 101-6
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Publication
23085235 | J:192195
First Author: Himes KP
Year: 2013
Journal: Dev Biol
Title: Generalized disruption of inherited genomic imprints leads to wide-ranging placental defects and dysregulated fetal growth.
Volume: 373
Issue: 1
Pages: 72-82
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Publication
23139813 | J:195360
First Author: Seibt J
Year: 2012
Journal: PLoS One
Title: Expression at the imprinted dlk1-gtl2 locus is regulated by proneural genes in the developing telencephalon.
Volume: 7
Issue: 11
Pages: e48675
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Publication
21937600 | J:178818
First Author: Wang B
Year: 2011
Journal: Development
Title: Transposon mutagenesis with coat color genotyping identifies an essential role for Skor2 in sonic hedgehog signaling and cerebellum development.
Volume: 138
Issue: 20
Pages: 4487-97
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Publication
12693553 | J:83413
First Author: Okazaki N
Year: 2003
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 10
Issue: 1
Pages: 35-48
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Publication
- | J:46439
     
First Author: Freeman TC
Year: 1998
Journal: MGI Direct Data Submission
Title: Expression Mapping of Mouse Genes
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Publication
- | J:72245
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:342608
       
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:72247
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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