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Search results 101 to 153 out of 153 for Rbm5

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Type Details Score
Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Allele
Rbm5<Gt(PST20293)Mfgc> | MGI:3902497
Name: RNA binding motif protein 5; gene trap PST20293, Mammalian Functional Genomics Centre
Allele Type: Gene trapped
Attribute String: Null/knockout
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Strain
MGI:6154938 | B6.129P2-Rbm5<Gt(PST20293)Mfgc>
Attribute String: congenic, gene trap, mutant strain
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Genotype
Genotype
Symbol: Rbm5/Rbm5
Background: B6.129P2-Rbm5
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rbm5/Rbm5<+>
Background: B6.129P2-Rbm5
Zygosity: ht
Has Mutant Allele: true
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Protein
A0A0A6YXE2
Organism: Mus musculus/domesticus
Length: 77  
Fragment?: true
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Publication
26712279 | -
First Author: Martin BT
Year: 2016
Journal: Structure
Title: Nuclear Magnetic Resonance Structure of a Novel Globular Domain in RBM10 Containing OCRE, the Octamer Repeat Sequence Motif.
Volume: 24
Issue: 1
Pages: 158-164
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Protein Domain
IPR041591 | OCRE
Type: Domain
Description: The OCtamer REpeat (OCRE) has been annotated as a 42-residue sequence motif with 12 tyrosine residues in the spliceosome trans-regulatory elements RBM5 and RBM10 (RBM [RNA-binding motif]), which are known to regulate alternative splicing of Fas and Bcl-x pre-mRNA transcripts []. The structure of the domain consists of an anti-parallel arrangement of six beta strands.
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Protein Domain
IPR028806 | RBM6
Type: Family
Description: RNA-binding protein 6 (RBM6) contains two RNA-binding motifs and shares protein sequence similarity with RBM5 []. RBM6 is targeted to the splicing speckles and nascent transcripts []. It may act mainly as a splicing activator []. The elevated expression of RBM6 has been linked to certain tumours []. A RBM6-CSF1R fusion has been found in acute megakaryoblastic leukemia [].
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Protein
Q9CRY1
Organism: Mus musculus/domesticus
Length: 244  
Fragment?: true
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Publication
10352938 | -
First Author: Timmer T
Year: 1999
Journal: Eur J Hum Genet
Title: A comparison of genomic structures and expression patterns of two closely related flanking genes in a critical lung cancer region at 3p21.3.
Volume: 7
Issue: 4
Pages: 478-86
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Publication
17908320 | -
 
First Author: Wang K
Year: 2007
Journal: BMC Genomics
Title: RBM6-RBM5 transcription-induced chimeras are differentially expressed in tumours.
Volume: 8
Pages: 348
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Publication
17360941 | -
First Author: Gu TL
Year: 2007
Journal: Blood
Title: A novel fusion of RBM6 to CSF1R in acute megakaryoblastic leukemia.
Volume: 110
Issue: 1
Pages: 323-33
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Publication
24332178 | -
First Author: Bechara EG
Year: 2013
Journal: Mol Cell
Title: RBM5, 6, and 10 differentially regulate NUMB alternative splicing to control cancer cell proliferation.
Volume: 52
Issue: 5
Pages: 720-33
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Publication
21086038 | -
First Author: Heath E
Year: 2010
Journal: Chromosome Res
Title: Subnuclear targeting of the RNA-binding motif protein RBM6 to splicing speckles and nascent transcripts.
Volume: 18
Issue: 8
Pages: 851-72
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Protein Domain
IPR035617 | RBM6_OCRE
Type: Domain
Description: RNA-binding protein 6 (RBM6) contains two RNA-binding motifs and shares protein sequence similarity with RBM5 []. RBM6 is targeted to the splicing speckles and nascent transcripts []. It may act mainly as a splicing activator []. The elevated expression of RBM6 has been linked to certain tumours []. A RBM6-CSF1R fusion has been found in acute megakaryoblastic leukemia [].RBM6 contains two RNA recognition motifs (RRMs), an OCtamer REpeat (OCRE) domain, two C2H2-type zinc fingers, a nuclear localization signal, and a G-patch/D111 domain. In contrast to RBM5, RBM6 has an additional unique domain, the POZ (poxvirus andzinc finger) domain, which may be involved in protein-protein interactions and inhibit binding of target sequences by zinc fingers. This entry represents the OCRE domain.The OCRE (OCtamer REpeat) domain contains five repeats of an 8-residue motif, which were shown to form β-strands. Based on the architectures of proteins containing OCRE domains, a role in RNA metabolism and/or signalling has been proposed [].
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Protein Domain
IPR034123 | RBM6_RRM1
Type: Domain
Description: This entry represents the RNA recognition motif 1 (RRM1) of RBM6 (also known as lung cancer antigen NY-LU-12, or protein G16, or RNA-binding protein DEF-3), which has been predicted to be a nuclear factor based on its nuclear localization signal [, , ]. RBM6 shows high sequence similarity to RNA-binding protein 5 (RBM5). Both RBM6 and RBM5 specifically bind poly(G) RNA. They contain two RNA recognition motifs (RRMs), also termed RBDs (RNA binding domains) or RNPs (ribonucleoprotein domains), two C2H2-type zinc fingers, a nuclear localization signal, and a G-patch/D111 domain. In contrast to RBM5, RBM6 has two additional unique domains: the decamer repeat occurring more than 20 times, and the POZ (poxvirus and zinc finger) domain. The POZ domain may be involved in protein-protein interactions and inhibit binding of target sequences by zinc fingers [, , ].
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Protein Domain
IPR034125 | RBM6_RRM2
Type: Domain
Description: This entry represents the RNA recognition motif 2 (RRM2) of RBM6 (also known as lung cancer antigen NY-LU-12, or protein G16, or RNA-binding protein DEF-3), which has been predicted to be a nuclear factor based on its nuclear localization signal [, , ]. RBM6 shows high sequence similarity to RNA-binding protein 5 (RBM5). Both RBM6 and RBM5 specifically bind poly(G) RNA. They contain two RNA recognition motifs (RRMs), also termed RBDs (RNA binding domains) or RNPs (ribonucleoprotein domains), two C2H2-type zinc fingers, a nuclear localization signal, and a G-patch/D111 domain. In contrast to RBM5, RBM6 has two additional unique domains: the decamer repeat occurring more than 20 times, and the POZ (poxvirus and zinc finger) domain. The POZ domain may be involved in protein-protein interactions and inhibit binding of target sequences by zinc fingers [, , ].
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Publication
10353602 | J:54520
First Author: Drabkin HA
Year: 1999
Journal: Oncogene
Title: DEF-3(g16/NY-LU-12), an RNA binding protein from the 3p21.3 homozygous deletion region in SCLC.
Volume: 18
Issue: 16
Pages: 2589-97
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Publication
9500467 | -
First Author: Güre AO
Year: 1998
Journal: Cancer Res
Title: Human lung cancer antigens recognized by autologous antibodies: definition of a novel cDNA derived from the tumor suppressor gene locus on chromosome 3p21.3.
Volume: 58
Issue: 5
Pages: 1034-41
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Publication
15514923 | -
First Author: Sutherland LC
Year: 2005
Journal: J Cell Biochem
Title: RNA binding motif (RBM) proteins: a novel family of apoptosis modulators?
Volume: 94
Issue: 1
Pages: 5-24
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Protein
A0A0A6YY54
Organism: Mus musculus/domesticus
Length: 187  
Fragment?: true
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Publication
22516180 | -
First Author: Mackereth CD
Year: 2012
Journal: Curr Opin Struct Biol
Title: Dynamics in multi-domain protein recognition of RNA.
Volume: 22
Issue: 3
Pages: 287-96
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Publication
22278943 | -
First Author: Muto Y
Year: 2012
Journal: Wiley Interdiscip Rev RNA
Title: Structural insight into RNA recognition motifs: versatile molecular Lego building blocks for biological systems.
Volume: 3
Issue: 2
Pages: 229-46
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Protein
Q3TPF1
Organism: Mus musculus/domesticus
Length: 463  
Fragment?: false
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Protein
S4R1W5
Organism: Mus musculus/domesticus
Length: 1118  
Fragment?: false
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Protein
O88720
Organism: Mus musculus/domesticus
Length: 1117  
Fragment?: false
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Protein
Q5DTS4
Organism: Mus musculus/domesticus
Length: 1109  
Fragment?: true
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Protein
Q3ULB0
Organism: Mus musculus/domesticus
Length: 986  
Fragment?: false
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Protein
Q3V1B3
Organism: Mus musculus/domesticus
Length: 612  
Fragment?: false
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Protein
Q7TN31
Organism: Mus musculus/domesticus
Length: 711  
Fragment?: false
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Publication
15486042 | -
First Author: Callebaut I
Year: 2005
Journal: Bioinformatics
Title: OCRE: a novel domain made of imperfect, aromatic-rich octamer repeats.
Volume: 21
Issue: 6
Pages: 699-702
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Protein
Q566J0
Organism: Mus musculus/domesticus
Length: 591  
Fragment?: true
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Protein
Q8BY56
Organism: Mus musculus/domesticus
Length: 557  
Fragment?: true
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Protein
Q99KG3
Organism: Mus musculus/domesticus
Length: 930  
Fragment?: false
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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