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Search results 401 to 491 out of 491 for Braf

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Category: Publication
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Type Details Score
Publication
35672316 | J:325350
First Author: Murphy BM
Year: 2022
Journal: Nat Commun
Title: Enhanced BRAF engagement by NRAS mutants capable of promoting melanoma initiation.
Volume: 13
Issue: 1
Pages: 3153
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Publication
29295999 | J:258475
First Author: Han S
Year: 2018
Journal: Nat Commun
Title: ERK-mediated phosphorylation regulates SOX10 sumoylation and targets expression in mutant BRAF melanoma.
Volume: 9
Issue: 1
Pages: 28
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Publication
29880484 | J:264050
First Author: Saei A
Year: 2018
Journal: J Exp Med
Title: Loss of USP28-mediated BRAF degradation drives resistance to RAF cancer therapies.
Volume: 215
Issue: 7
Pages: 1913-1928
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Publication
19079609 | J:144358
First Author: Jeong JH
Year: 2008
Journal: PLoS One
Title: BRAF activation initiates but does not maintain invasive prostate adenocarcinoma.
Volume: 3
Issue: 12
Pages: e3949
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Publication
28174173 | J:240401
First Author: Wan L
Year: 2017
Journal: Cancer Discov
Title: The APC/C E3 Ligase Complex Activator FZR1 Restricts BRAF Oncogenic Function.
Volume: 7
Issue: 4
Pages: 424-441
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Publication
22693252 | J:189290
First Author: Koya RC
Year: 2012
Journal: Cancer Res
Title: BRAF inhibitor vemurafenib improves the antitumor activity of adoptive cell immunotherapy.
Volume: 72
Issue: 16
Pages: 3928-37
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Publication
29540830 | J:263924
First Author: Dankner M
Year: 2018
Journal: Oncogene
Title: Classifying BRAF alterations in cancer: new rational therapeutic strategies for actionable mutations.
Volume: 37
Issue: 24
Pages: 3183-3199
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Publication
10051318 | J:53815
First Author: Vacher J
Year: 1999
Journal: Mamm Genome
Title: Genetic localization and transmission of the mouse osteopetrotic grey-lethal mutation.
Volume: 10
Issue: 3
Pages: 239-43
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Publication
8455932 | J:4634
First Author: Wadewitz AG
Year: 1993
Journal: Oncogene
Title: Developmental and cell lineage specificity of raf family gene expression in mouse testis.
Volume: 8
Issue: 4
Pages: 1055-62
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Publication
25843629 | J:222864
First Author: Karreth FA
Year: 2015
Journal: Cell
Title: The BRAF pseudogene functions as a competitive endogenous RNA and induces lymphoma in vivo.
Volume: 161
Issue: 2
Pages: 319-32
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Publication
24828987 | J:214390
First Author: Gandolfi G
Year: 2015
Journal: Int J Cancer
Title: Time to re-consider the meaning of BRAF V600E mutation in papillary thyroid carcinoma.
Volume: 137
Issue: 5
Pages: 1001-11
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Publication
28404629 | J:242910
First Author: Lim CS
Year: 2017
Journal: Genes Dev
Title: BRaf signaling principles unveiled by large-scale human mutation analysis with a rapid lentivirus-based gene replacement method.
Volume: 31
Issue: 6
Pages: 537-552
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Publication
26541605 | J:299365
First Author: Yun J
Year: 2015
Journal: Science
Title: Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH.
Volume: 350
Issue: 6266
Pages: 1391-6
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Publication
25109331 | J:222531
First Author: Riemer P
Year: 2015
Journal: Oncogene
Title: Transgenic expression of oncogenic BRAF induces loss of stem cells in the mouse intestine, which is antagonized by β-catenin activity.
Volume: 34
Issue: 24
Pages: 3164-75
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Publication
29433126 | -
First Author: Lavoie H
Year: 2018
Journal: Nature
Title: MEK drives BRAF activation through allosteric control of KSR proteins.
Volume: 554
Issue: 7693
Pages: 549-553
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Publication
26286024 | J:260644
First Author: Ramsdale R
Year: 2015
Journal: Sci Signal
Title: The transcription cofactor c-JUN mediates phenotype switching and BRAF inhibitor resistance in melanoma.
Volume: 8
Issue: 390
Pages: ra82
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Publication
25351955 | J:218275
First Author: Ferrari de Andrade L
Year: 2014
Journal: Cancer Res
Title: Natural killer cells are essential for the ability of BRAF inhibitors to control BRAFV600E-mutant metastatic melanoma.
Volume: 74
Issue: 24
Pages: 7298-308
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Publication
22256804 | J:181162
First Author: Su F
Year: 2012
Journal: N Engl J Med
Title: RAS mutations in cutaneous squamous-cell carcinomas in patients treated with BRAF inhibitors.
Volume: 366
Issue: 3
Pages: 207-15
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Publication
33206716 | J:297542
First Author: Younes ST
Year: 2020
Journal: PLoS One
Title: In silico analysis identifies a putative cell-of-origin for BRAF fusion-positive cerebellar pilocytic astrocytoma.
Volume: 15
Issue: 11
Pages: e0242521
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Publication
24163374 | J:208914
First Author: Faber AC
Year: 2014
Journal: Cancer Discov
Title: mTOR inhibition specifically sensitizes colorectal cancers with KRAS or BRAF mutations to BCL-2/BCL-XL inhibition by suppressing MCL-1.
Volume: 4
Issue: 1
Pages: 42-52
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Publication
9799843 | J:50580
First Author: Wojnowski L
Year: 1998
Journal: Mamm Genome
Title: Reduced activity of BRAF protein kinase in hop and hop(hpy) mouse mutants.
Volume: 9
Issue: 11
Pages: 905-6
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Publication
28827320 | J:250257
First Author: Duggan MC
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Identification of NRAS isoform 2 overexpression as a mechanism facilitating BRAF inhibitor resistance in malignant melanoma.
Volume: 114
Issue: 36
Pages: 9629-9634
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Publication
17510423 | J:121738
First Author: Ji H
Year: 2007
Journal: Cancer Res
Title: Mutations in BRAF and KRAS converge on activation of the mitogen-activated protein kinase pathway in lung cancer mouse models.
Volume: 67
Issue: 10
Pages: 4933-9
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Publication
26248136 | J:232891
First Author: Zhang ZX
Year: 2015
Journal: Biochem Biophys Res Commun
Title: BRAF activated non-coding RNA (BANCR) promoting gastric cancer cells proliferation via regulation of NF-κB1.
Volume: 465
Issue: 2
Pages: 225-31
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Publication
18974108 | -
First Author: Jones DT
Year: 2008
Journal: Cancer Res
Title: Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas.
Volume: 68
Issue: 21
Pages: 8673-7
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Publication
28910386 | J:249827
First Author: Buffet C
Year: 2017
Journal: PLoS One
Title: DUSP5 and DUSP6, two ERK specific phosphatases, are markers of a higher MAPK signaling activation in BRAF mutated thyroid cancers.
Volume: 12
Issue: 9
Pages: e0184861
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Publication
19363522 | -
First Author: Jones DT
Year: 2009
Journal: Oncogene
Title: Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma.
Volume: 28
Issue: 20
Pages: 2119-23
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Publication
16753739 | -
First Author: Lee JH
Year: 2006
Journal: Pathology
Title: BRAF mutation and AKAP9 expression in sporadic papillary thyroid carcinomas.
Volume: 38
Issue: 3
Pages: 201-4
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Publication
23441035 | J:196873
First Author: Ortiz O
Year: 2013
Journal: Genesis
Title: Reversible and tissue-specific activation of MAP kinase signaling by tamoxifen in Braf(V637)ER(T2) mice.
Volume: 51
Issue: 6
Pages: 448-55
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Publication
32719131 | J:293934
First Author: Niitsu Y
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: A CRAF/glutathione-S-transferase P1 complex sustains autocrine growth of cancers with KRAS and BRAF mutations.
Volume: 117
Issue: 32
Pages: 19435-19445
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Publication
19937730 | -
First Author: Tatevossian RG
Year: 2010
Journal: J Cell Physiol
Title: MAPK pathway activation and the origins of pediatric low-grade astrocytomas.
Volume: 222
Issue: 3
Pages: 509-14
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Publication
22318779 | J:189130
First Author: Rebocho AP
Year: 2011
Journal: Cancer Discov
Title: New insight puts CRAF in sight as a therapeutic target.
Volume: 1
Issue: 2
Pages: 98-9
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Publication
23893969 | J:204469
First Author: Kaul A
Year: 2013
Journal: Genesis
Title: Conditional KIAA1549:BRAF mice reveal brain region- and cell type-specific effects.
Volume: 51
Issue: 10
Pages: 708-16
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Publication
22340588 | J:181465
First Author: Cox AD
Year: 2012
Journal: Cancer Cell
Title: The RAF inhibitor paradox revisited.
Volume: 21
Issue: 2
Pages: 147-9
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Publication
23845435 | J:199225
First Author: Rustgi AK
Year: 2013
Journal: Cancer Cell
Title: BRAF: a driver of the serrated pathway in colon cancer.
Volume: 24
Issue: 1
Pages: 1-2
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Publication
25584887 | J:218896
First Author: Souroullas GP
Year: 2015
Journal: Cancer Cell
Title: mTOR signaling in melanoma: oncogene-induced pseudo-senescence?
Volume: 27
Issue: 1
Pages: 3-5
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Publication
27261482 | J:236808
First Author: Virós A
Year: 2016
Journal: Cancer Discov
Title: So You Can Teach Old Fibroblasts New Tricks.
Volume: 6
Issue: 6
Pages: 581-3
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Publication
23152448 | J:191207
First Author: Kaul A
Year: 2012
Journal: Genes Dev
Title: Pediatric glioma-associated KIAA1549:BRAF expression regulates neuroglial cell growth in a cell type-specific and mTOR-dependent manner.
Volume: 26
Issue: 23
Pages: 2561-6
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Publication
24860158 | J:217846
First Author: Strohecker AM
Year: 2014
Journal: Cancer Discov
Title: Targeting mitochondrial metabolism by inhibiting autophagy in BRAF-driven cancers.
Volume: 4
Issue: 7
Pages: 766-72
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Publication
15716956 | J:96202
First Author: Carreira S
Year: 2005
Journal: Nature
Title: Mitf cooperates with Rb1 and activates p21Cip1 expression to regulate cell cycle progression.
Volume: 433
Issue: 7027
Pages: 764-9
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Publication
29654229 | J:261939
First Author: Oldrini B
Year: 2018
Journal: Nat Commun
Title: Somatic genome editing with the RCAS-TVA-CRISPR-Cas9 system for precision tumor modeling.
Volume: 9
Issue: 1
Pages: 1466
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Publication
28514651 | J:255883
First Author: Kwong LN
Year: 2017
Journal: Cell Rep
Title: Modeling Genomic Instability and Selection Pressure in a Mouse Model of Melanoma.
Volume: 19
Issue: 7
Pages: 1304-1312
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Publication
22820643 | J:317304
First Author: Gembarska A
Year: 2012
Journal: Nat Med
Title: MDM4 is a key therapeutic target in cutaneous melanoma.
Volume: 18
Issue: 8
Pages: 1239-47
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Publication
33674596 | J:304975
First Author: Ischenko I
Year: 2021
Journal: Nat Commun
Title: KRAS drives immune evasion in a genetic model of pancreatic cancer.
Volume: 12
Issue: 1
Pages: 1482
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Publication
15024079 | J:89066
First Author: Goodall J
Year: 2004
Journal: Mol Cell Biol
Title: Brn-2 expression controls melanoma proliferation and is directly regulated by beta-catenin.
Volume: 24
Issue: 7
Pages: 2915-22
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Publication
23178117 | J:196210
First Author: Huang S
Year: 2012
Journal: Cell
Title: MED12 controls the response to multiple cancer drugs through regulation of TGF-β receptor signaling.
Volume: 151
Issue: 5
Pages: 937-50
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Publication
21835307 | J:189266
First Author: Abu-Safieh L
Year: 2011
Journal: Am J Hum Genet
Title: Mutation of IGFBP7 causes upregulation of BRAF/MEK/ERK pathway and familial retinal arterial macroaneurysms.
Volume: 89
Issue: 2
Pages: 313-9
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Publication
23069660 | J:199972
First Author: Fedorenko IV
Year: 2013
Journal: Oncogene
Title: NRAS mutant melanoma: biological behavior and future strategies for therapeutic management.
Volume: 32
Issue: 25
Pages: 3009-18
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Publication
30061422 | J:266274
First Author: Yang Y
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Central role of autophagic UVRAG in melanogenesis and the suntan response.
Volume: 115
Issue: 33
Pages: E7728-E7737
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Publication
31302002 | J:279873
First Author: Colomer C
Year: 2019
Journal: Mol Cell
Title: IKKα Kinase Regulates the DNA Damage Response and Drives Chemo-resistance in Cancer.
Volume: 75
Issue: 4
Pages: 669-682.e5
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Publication
31940493 | J:287418
First Author: Rosenbaum SR
Year: 2020
Journal: Cell Rep
Title: FOXD3 Regulates VISTA Expression in Melanoma.
Volume: 30
Issue: 2
Pages: 510-524.e6
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Publication
30471144 | J:321181
First Author: Moon H
Year: 2019
Journal: Exp Dermatol
Title: Sirt5 is dispensable for BrafV600E -mediated cutaneous melanoma development and growth in vivo.
Volume: 28
Issue: 1
Pages: 83-85
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Publication
35332119 | J:322998
First Author: Zhang P
Year: 2022
Journal: Nat Commun
Title: Targeting myeloid derived suppressor cells reverts immune suppression and sensitizes BRAF-mutant papillary thyroid cancer to MAPK inhibitors.
Volume: 13
Issue: 1
Pages: 1588
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Publication
38092754 | J:343423
First Author: Muta Y
Year: 2023
Journal: Nat Commun
Title: Enhanced SREBP2-driven cholesterol biosynthesis by PKCλ/ι deficiency in intestinal epithelial cells promotes aggressive serrated tumorigenesis.
Volume: 14
Issue: 1
Pages: 8075
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Publication
29523762 | J:261905
First Author: Peyret V
Year: 2018
Journal: Mol Cancer Res
Title: Functional Toll-like Receptor 4 Overexpression in Papillary Thyroid Cancer by MAPK/ERK-Induced ETS1 Transcriptional Activity.
Volume: 16
Issue: 5
Pages: 833-845
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28263969 | J:243371
First Author: Yang H
Year: 2017
Journal: Oncogene
Title: Activated MEK cooperates with Cdkn2a and Pten loss to promote the development and maintenance of melanoma.
Volume: 36
Issue: 27
Pages: 3842-3851
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Publication
22983396 | J:238049
First Author: Kwong LN
Year: 2012
Journal: Nat Med
Title: Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma.
Volume: 18
Issue: 10
Pages: 1503-10
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Publication
16510579 | J:106704
First Author: van Schanke A
Year: 2006
Journal: Cancer Res
Title: Induction of nevi and skin tumors in Ink4a/Arf Xpa knockout mice by neonatal, intermittent, or chronic UVB exposures.
Volume: 66
Issue: 5
Pages: 2608-15
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18472967 | J:138670
First Author: Lyustikman Y
Year: 2008
Journal: Neoplasia
Title: Constitutive activation of Raf-1 induces glioma formation in mice.
Volume: 10
Issue: 5
Pages: 501-10
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17575131 | J:122413
First Author: Yang G
Year: 2007
Journal: Cancer Res
Title: Loss of xeroderma pigmentosum C (Xpc) enhances melanoma photocarcinogenesis in Ink4a-Arf-deficient mice.
Volume: 67
Issue: 12
Pages: 5649-57
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21203491 | J:167512
First Author: Shah M
Year: 2010
Journal: PLoS Genet
Title: A role for ATF2 in regulating MITF and melanoma development.
Volume: 6
Issue: 12
Pages: e1001258
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Publication
38182748 | J:344309
First Author: Tzenaki N
Year: 2024
Journal: Commun Biol
Title: A combined opposite targeting of p110δ PI3K and RhoA abrogates skin cancer.
Volume: 7
Issue: 1
Pages: 26
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24129679 | J:206060
First Author: Doma E
Year: 2013
Journal: Cancer Res
Title: Skin tumorigenesis stimulated by Raf inhibitors relies upon Raf functions that are dependent and independent of ERK.
Volume: 73
Issue: 23
Pages: 6926-37
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23603816 | J:198505
First Author: Jameson KL
Year: 2013
Journal: Nat Med
Title: IQGAP1 scaffold-kinase interaction blockade selectively targets RAS-MAP kinase-driven tumors.
Volume: 19
Issue: 5
Pages: 626-630
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29748372 | J:264288
First Author: Wang Q
Year: 2018
Journal: Cancer Res
Title: TRAF1 Is Critical for Regulating the BRAF/MEK/ERK Pathway in Non-Small Cell Lung Carcinogenesis.
Volume: 78
Issue: 14
Pages: 3982-3994
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Publication
29885461 | J:271171
 
First Author: Hutchenreuther J
Year: 2018
Journal: Matrix Biol
Title: Activation of cancer-associated fibroblasts is required for tumor neovascularization in a murine model of melanoma.
Volume: 74
Pages: 52-61
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21734707 | J:287767
First Author: DeNicola GM
Year: 2011
Journal: Nature
Title: Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis.
Volume: 475
Issue: 7354
Pages: 106-9
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26168233 | J:226336
First Author: Hutchenreuther J
Year: 2015
Journal: J Invest Dermatol
Title: CCN2 Expression by Tumor Stroma Is Required for Melanoma Metastasis.
Volume: 135
Issue: 11
Pages: 2805-2813
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37833251 | J:344096
First Author: Hao W
Year: 2023
Journal: Cell Death Dis
Title: Critical role of VHL/BICD2/STAT1 axis in crystal-associated kidney disease.
Volume: 14
Issue: 10
Pages: 680
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Publication
23893239 | J:212616
First Author: Albinet V
Year: 2014
Journal: Oncogene
Title: Dual role of sphingosine kinase-1 in promoting the differentiation of dermal fibroblasts and the dissemination of melanoma cells.
Volume: 33
Issue: 26
Pages: 3364-73
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Publication
30987979 | J:274179
First Author: Shah R
Year: 2019
Journal: Cancer Res
Title: Concurrent Targeting of Glutaminolysis and Metabotropic Glutamate Receptor 1 (GRM1) Reduces Glutamate Bioavailability in GRM1+ Melanoma.
Volume: 79
Issue: 8
Pages: 1799-1809
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28450382 | J:243438
First Author: Young HL
Year: 2017
Journal: J Exp Med
Title: An adaptive signaling network in melanoma inflammatory niches confers tolerance to MAPK signaling inhibition.
Volume: 214
Issue: 6
Pages: 1691-1710
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Publication
23222297 | J:194374
First Author: Marais R
Year: 2013
Journal: Cancer Res
Title: Twenty-fourth annual Pezcoller symposium: Molecular basis for resistance to targeted agents.
Volume: 73
Issue: 3
Pages: 1046-9
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25597784 | J:219971
First Author: Strickland LR
Year: 2015
Journal: Cancer Lett
Title: Targeting drivers of melanoma with synthetic small molecules and phytochemicals.
Volume: 359
Issue: 1
Pages: 20-35
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Publication
25395294 | J:220618
First Author: Wargo JA
Year: 2014
Journal: Cancer Discov
Title: Universes collide: combining immunotherapy with targeted therapy for cancer.
Volume: 4
Issue: 12
Pages: 1377-86
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26603897 | J:227251
First Author: Feng Y
Year: 2015
Journal: Cancer Res
Title: SBI-0640756 Attenuates the Growth of Clinically Unresponsive Melanomas by Disrupting the eIF4F Translation Initiation Complex.
Volume: 75
Issue: 24
Pages: 5211-8
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Publication
25026375 | J:230126
 
First Author: Mehrotra A
Year: 2014
Journal: Arch Biochem Biophys
Title: Modulation of Brahma expression by the mitogen-activated protein kinase/extracellular signal regulated kinase pathway is associated with changes in melanoma proliferation.
Volume: 563
Pages: 125-35
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Publication
31351087 | J:278931
 
First Author: Laudisi F
Year: 2019
Journal: Cancer Lett
Title: Induction of endoplasmic reticulum stress and inhibition of colon carcinogenesis by the anti-helmintic drug rafoxanide.
Volume: 462
Pages: 1-11
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Publication
31065107 | J:303002
First Author: Laurette P
Year: 2020
Journal: Cell Death Differ
Title: Chromatin remodellers Brg1 and Bptf are required for normal gene expression and progression of oncogenic Braf-driven mouse melanoma.
Volume: 27
Issue: 1
Pages: 29-43
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Publication
34210801 | J:308465
 
First Author: Bowman RL
Year: 2021
Journal: Life Sci Alliance
Title: UVB mutagenesis differs in Nras- and Braf-mutant mouse models of melanoma.
Volume: 4
Issue: 9
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Publication
33743547 | J:307675
First Author: Kanazawa K
Year: 2021
Journal: Cancer Sci
Title: Ppp6c haploinsufficiency accelerates UV-induced BRAF(V600E)-initiated melanomagenesis.
Volume: 112
Issue: 6
Pages: 2233-2244
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32629543 | J:313360
First Author: Kochi M
Year: 2020
Journal: Cancer Sci
Title: Oncogenic mutation in RAS-RAF axis leads to increased expression of GREB1, resulting in tumor proliferation in colorectal cancer.
Volume: 111
Issue: 10
Pages: 3540-3549
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Publication
37870961 | J:342136
 
First Author: Sánchez-Tilló E
Year: 2023
Journal: JCI Insight
Title: The EMT factor ZEB1 paradoxically inhibits EMT in BRAF-mutant carcinomas.
Volume: 8
Issue: 20
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Publication
25246427 | J:264174
First Author: Kaul A
Year: 2015
Journal: Neuro Oncol
Title: The impact of coexisting genetic mutations on murine optic glioma biology.
Volume: 17
Issue: 5
Pages: 670-7
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Publication
23372702 | J:195921
First Author: Ryder M
Year: 2013
Journal: PLoS One
Title: Genetic and pharmacological targeting of CSF-1/CSF-1R inhibits tumor-associated macrophages and impairs BRAF-induced thyroid cancer progression.
Volume: 8
Issue: 1
Pages: e54302
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Publication
19064922 | J:166283
First Author: Su Q
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: A DNA transposon-based approach to validate oncogenic mutations in the mouse.
Volume: 105
Issue: 50
Pages: 19904-9
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Publication
22643351 | J:292907
First Author: Bongers G
Year: 2012
Journal: Gastroenterology
Title: A role for the epidermal growth factor receptor signaling in development of intestinal serrated polyps in mice and humans.
Volume: 143
Issue: 3
Pages: 730-740
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Publication
28192409 | J:243383
First Author: Tonks ID
Year: 2017
Journal: Oncogene
Title: Melanocyte transformation requires complete loss of all pocket protein function via a mechanism that mitigates the need for MAPK pathway activation.
Volume: 36
Issue: 26
Pages: 3789-3795
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Publication
37415974 | J:337739
 
First Author: Jacenik D
Year: 2023
Journal: Front Immunol
Title: MK2 drives progression of pancreas and colon cancers by suppressing CD8(+) T cell cytotoxic function and is a potential immunotherapy target.
Volume: 14
Pages: 1212100
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Publication
17586814 | J:133638
First Author: Hitz C
Year: 2007
Journal: Nucleic Acids Res
Title: Conditional brain-specific knockdown of MAPK using Cre/loxP regulated RNA interference.
Volume: 35
Issue: 12
Pages: e90
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Publication
- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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