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Search results 101 to 200 out of 222 for Nup98

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Type Details Score
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
16033648 | J:103446
 
First Author: McKee AE
Year: 2005
Journal: BMC Dev Biol
Title: A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.
Volume: 5
Pages: 14
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Publication
12477932 | J:82808
First Author: Strausberg RL
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Volume: 99
Issue: 26
Pages: 16899-903
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Publication
15226823 | J:93300
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Protein Domain
IPR029280 | LNP1
Type: Family
Description: This family of proteins includes leukemia NUP98 fusion partner 1, the gene encoding this protein is involved in a chromosomal translocation with the NUP98 locus in a form of T-cell acute lymphoblastic leukemia [].
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Gene
739703 | LNP1
Type: gene
Organism: chimpanzee
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Gene
478542 | LNP1
Type: gene
Organism: dog, domestic
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Gene
507217 | LNP1
Type: gene
Organism: cattle
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Gene
100359918 | Lnp1
Type: gene
Organism: rat
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Gene
418388 | LNP1
Type: gene
Organism: chicken
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Gene
700480 | LNP1
Type: gene
Organism: macaque, rhesus
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Gene
101731413 | lnp1
Type: gene
Organism: frog, western clawed
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Gene
108707916 | LOC108707916
Type: gene
Organism: frog, African clawed
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Protein Coding Gene
MGI_C57BL6J_5011982 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
8563753 | J:142951
First Author: Nakamura T
Year: 1996
Journal: Nat Genet
Title: Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemia.
Volume: 12
Issue: 2
Pages: 154-8
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UniProt Feature
UniProt Feature
Begin: 1
Description: Nuclear pore complex protein Nup98
Type: chain
End: 880
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Component
Component
Name: Nuclear pore complex protein Nup98
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Publication
29269482 | J:260454
First Author: Franks TM
Year: 2017
Journal: Genes Dev
Title: Nup98 recruits the Wdr82-Set1A/COMPASS complex to promoters to regulate H3K4 trimethylation in hematopoietic progenitor cells.
Volume: 31
Issue: 22
Pages: 2222-2234
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Allele
Lnp1<+> | MGI:5012957
 
Name: leukemia NUP98 fusion partner 1; wild type
Allele Type: Not Specified
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Publication
23102701 | J:194005
First Author: Singer S
Year: 2012
Journal: Mol Cell
Title: Nuclear pore component Nup98 is a potential tumor suppressor and regulates posttranscriptional expression of select p53 target genes.
Volume: 48
Issue: 5
Pages: 799-810
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Allele
Lnp1<Gt(OST19736)Lex> | MGI:4143530
 
Name: leukemia NUP98 fusion partner 1; gene trap OST19736, Lexicon Genetics
Allele Type: Gene trapped
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Interaction Experiment
Stuwe T (2012)
Description: Molecular Basis for the Anchoring of Proto-Oncoprotein Nup98 to the Cytoplasmic Face of the Nuclear Pore Complex.
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Publication
12589057 | -
First Author: Griffis ER
Year: 2003
Journal: Mol Biol Cell
Title: Nup98 localizes to both nuclear and cytoplasmic sides of the nuclear pore and binds to two distinct nucleoporin subcomplexes.
Volume: 14
Issue: 2
Pages: 600-10
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Publication
10209021 | -
First Author: Pritchard CE
Year: 1999
Journal: J Cell Biol
Title: RAE1 is a shuttling mRNA export factor that binds to a GLEBS-like NUP98 motif at the nuclear pore complex through multiple domains.
Volume: 145
Issue: 2
Pages: 237-54
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Publication
21467841 | J:303147
First Author: Funasaka T
Year: 2011
Journal: Cell Cycle
Title: RNA export factor RAE1 contributes to NUP98-HOXA9-mediated leukemogenesis.
Volume: 10
Issue: 9
Pages: 1456-67
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Publication
15454493 | J:96544
First Author: Iwasaki M
Year: 2005
Journal: Blood
Title: Identification of cooperative genes for NUP98-HOXA9 in myeloid leukemogenesis using a mouse model.
Volume: 105
Issue: 2
Pages: 784-93
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Allele
Nup98<tm1Bmaf> | MGI:3653729
Name: nucleoporin 98; targeted mutation 1, Beatriz M A Fontoura
Allele Type: Targeted
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Nup98/Nup98<+>
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Allele
Tg(CTSG-NUP98/HOXA9)1589Tanak | MGI:3822555
Name: transgene insertion 1589, Takuro Nakamura
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
28210005 | J:245733
First Author: Shima Y
Year: 2017
Journal: Leukemia
Title: MLL is essential for NUP98-HOXA9-induced leukemia.
Volume: 31
Issue: 10
Pages: 2200-2210
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Strain
MGI:6144587 | B6.Cg-Tg(CTSG-NUP98/HOXA9)1589Tanak/TanakRbrc
Attribute String: mutant strain, congenic, transgenic
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Publication
8090757 | J:47502
First Author: Grisolano JL
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Early myeloid cell-specific expression of the human cathepsin G gene in transgenic mice.
Volume: 91
Issue: 19
Pages: 8989-93
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Protein
Q3TP40
Organism: Mus musculus/domesticus
Length: 374  
Fragment?: true
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Protein
Q9EQM8
Organism: Mus musculus/domesticus
Length: 196  
Fragment?: true
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Publication
11104765 | -
First Author: Strawn LA
Year: 2001
Journal: J Biol Chem
Title: The GLFG regions of Nup116p and Nup100p serve as binding sites for both Kap95p and Mex67p at the nuclear pore complex.
Volume: 276
Issue: 9
Pages: 6445-52
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Protein Domain
IPR037637 | NUP98-NUP96
Type: Family
Description: The entry includes components of the nuclear pore complex (NPC), which is required for transport of macromolecules in and out of the nucleus. These components are all nucleoporins. Components Nup98 and Nup96 are products of autolytic processing of a precursor protein that is effectively a serine endopeptidase (MEROPS identifier S59.001). The precursor is known as Nup189 in Schizosaccharomyces pombe. This entry also includes nucleoporin Nup100 from Saccharomyces cerevisiae, which does not process itself but which is important for poly(A)+ RNA and protein transport. Nup100 has a tetrapeptide glycine-leucine-phenylalanine-glycine (GLFG) motif where it binds karyopherin transport factor Kap95p [].
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Protein
Q3TPG3
Organism: Mus musculus/domesticus
Length: 861  
Fragment?: false
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Protein
Q3UJE5
Organism: Mus musculus/domesticus
Length: 984  
Fragment?: false
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Protein
A0A140T8J8
Organism: Mus musculus/domesticus
Length: 1187  
Fragment?: false
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Protein
A0A1B0GS62
Organism: Mus musculus/domesticus
Length: 230  
Fragment?: true
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Protein
A0A1B0GRA7
Organism: Mus musculus/domesticus
Length: 984  
Fragment?: false
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Protein
A0A1B0GRB5
Organism: Mus musculus/domesticus
Length: 967  
Fragment?: false
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Publication
11684705 | J:114791
First Author: Vasu S
Year: 2001
Journal: J Cell Biol
Title: Novel vertebrate nucleoporins Nup133 and Nup160 play a role in mRNA export.
Volume: 155
Issue: 3
Pages: 339-54
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Publication
10542288 | -
First Author: Teixeira MT
Year: 1999
Journal: J Biol Chem
Title: Self-catalyzed cleavage of the yeast nucleoporin Nup145p precursor.
Volume: 274
Issue: 45
Pages: 32439-44
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Publication
20310066 | -
First Author: Sampathkumar P
Year: 2010
Journal: Proteins
Title: Structures of the autoproteolytic domain from the Saccharomyces cerevisiae nuclear pore complex component, Nup145.
Volume: 78
Issue: 8
Pages: 1992-8
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Publication
8195299 | -
First Author: Wente SR
Year: 1994
Journal: J Cell Biol
Title: NUP145 encodes a novel yeast glycine-leucine-phenylalanine-glycine (GLFG) nucleoporin required for nuclear envelope structure.
Volume: 125
Issue: 5
Pages: 955-69
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Publication
26137436 | -
 
First Author: Asakawa H
Year: 2015
Journal: FEBS Open Bio
Title: Uncleavable Nup98-Nup96 is functional in the fission yeast Schizosaccharomyces pombe.
Volume: 5
Pages: 508-14
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Protein Domain
IPR037665 | Nucleoporin_S59-like
Type: Family
Description: This entry represents nucleoporins, of which the precursors of some undergo autolytic processing. Some nucleoporins are synthesized as precursors, and each of these processes itself to release two large fragments that are both nucleoporins. Cleavage is dependent upon a His/Ser catalytic dyad, and cleavage occurs at the N-terminal side of the catalytic Ser. This means that the nucleoporin precursors are N-terminal nucleophile (NTN) hydrolases, but are structurally unrelated to other NTN hydrolases which are also peptidases, such as proteosome components. Autoprocessing nucleoporin precursors are members of peptidase family S59. The precursor Nup98-Nup96 (also known as nucleoporin 145 in Saccharomyces cerevisiae and Nup189 in Schizosaccharomyces pombe) processes itself to release Nup98 and Nup96 [, , ]. Nucleoporins Nup98 and Nup96 are components of the nuclear pore complex (NPC), which is the only means by which macromolecules enter and exit the nucleus. Other nucleoporins in family S59 are not synthesized as precursors and do not undergo autoprocessing, such as Nup100 (from Saccharomyces cerevisiae). Nup100 is also a component of the NPC and binds the karyopherin transport factor Kap95 at its repetitive tetrapeptide glycine-leucine-phenylalanine-glycine (GLFG) motifs [].
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Protein Domain
IPR021967 | Nup98_C
Type: Domain
Description: This entry represents the Nuclear pore complex protein Nup96 from animals its homologues from yeast and plants.Nuclear pore complexes (NPCs) facilitate all nucleocytoplasmic transport in eukaryotic cells, playing essential roles in cellular homeostasis. The NPC is a modular structure composed of multiple copies of ~30 proteins (nucleoporins, Nups) arranged into distinct subcomplexes [, ]. A number of these peptides are synthesised as precursors and undergo self-catalyzed cleavage. The largest NPC sub-complex is the heptameric Y-shaped mammalian Nup107-Nup160 complex (called Nup84 complex in budding yeast), an essential scaffolding component of the NPC [, , ]. Nup98 and Nup96 are encoded by the same gene that produces a 190 kDa polyprotein with autoproteolytic activity which generates the N-terminal NUP98 and C-terminal NUP96 proteins, part of the Nup107-Nup160 subcomplex [, ]. The yeast homologue Nup145 undergoes the similar proteolytic event to produce Nup145N and Nup145C, which are part of the Nup84 complex. The function of the heptamer is to coat the curvature of the nuclear pore complex between the inner and outer nuclear membranes. Nup96, which is predicted to be an alpha helical solenoid, complexes with Sec13 in the middle of the heptamer. The interaction between Nup96 and Sec13 is the point of curvature in the heptameric complex [, ].
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Publication
12191467 | -
First Author: Dokudovskaya S
Year: 2002
Journal: Mol Cell
Title: Cleave to leave: structural insights into the dynamic organization of the nuclear pore complex.
Volume: 10
Issue: 2
Pages: 221-3
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Publication
16105837 | -
First Author: Robinson MA
Year: 2005
Journal: J Biol Chem
Title: Multiple conformations in the ligand-binding site of the yeast nuclear pore-targeting domain of Nup116p.
Volume: 280
Issue: 42
Pages: 35723-32
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Publication
18160040 | -
First Author: Hsia KC
Year: 2007
Journal: Cell
Title: Architecture of a coat for the nuclear pore membrane.
Volume: 131
Issue: 7
Pages: 1313-26
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Publication
30943044 | -
 
First Author: Hampoelz B
Year: 2019
Journal: Annu Rev Biophys
Title: Structure and Assembly of the Nuclear Pore Complex.
Volume: 48
Pages: 515-536
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Publication
33159083 | -
First Author: Kramarz K
Year: 2020
Journal: Nat Commun
Title: The nuclear pore primes recombination-dependent DNA synthesis at arrested forks by promoting SUMO removal.
Volume: 11
Issue: 1
Pages: 5643
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Publication
33247142 | -
First Author: Nordeen SA
Year: 2020
Journal: Nat Commun
Title: Yeast Nup84-Nup133 complex structure details flexibility and reveals conservation of the membrane anchoring ALPS motif.
Volume: 11
Issue: 1
Pages: 6060
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Publication
21326946 | -
First Author: Debler EW
Year: 2010
Journal: Nucleus
Title: Characterization of the membrane-coating Nup84 complex: paradigm for the nuclear pore complex structure.
Volume: 1
Issue: 2
Pages: 150-7
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Publication
19855394 | -
First Author: Brohawn SG
Year: 2009
Journal: Nat Struct Mol Biol
Title: Molecular architecture of the Nup84-Nup145C-Sec13 edge element in the nuclear pore complex lattice.
Volume: 16
Issue: 11
Pages: 1173-7
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Protein
Q6PFD9
Organism: Mus musculus/domesticus
Length: 1816  
Fragment?: false
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Protein
A0A1B0GSX7
Organism: Mus musculus/domesticus
Length: 1816  
Fragment?: false
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Publication
30189209 | J:269833
First Author: Eftekharzadeh B
Year: 2018
Journal: Neuron
Title: Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease.
Volume: 99
Issue: 5
Pages: 925-940.e7
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Publication
15755899 | J:107446
First Author: Lin YW
Year: 2005
Journal: Blood
Title: NUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that progresses to acute leukemia.
Volume: 106
Issue: 1
Pages: 287-95
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Publication
18648006 | J:140463
 
First Author: Slape C
Year: 2008
Journal: J Natl Cancer Inst Monogr
Title: NUP98-HOX translocations lead to myelodysplastic syndrome in mice and men.
Issue: 39
Pages: 64-8
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Publication
11157742 | J:67131
First Author: Kroon E
Year: 2001
Journal: EMBO J
Title: NUP98-HOXA9 expression in hemopoietic stem cells induces chronic and acute myeloid leukemias in mice.
Volume: 20
Issue: 3
Pages: 350-61
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Publication
26740045 | J:229934
 
First Author: Oka M
Year: 2016
Journal: Elife
Title: Chromatin-prebound Crm1 recruits Nup98-HoxA9 fusion to induce aberrant expression of Hox cluster genes.
Volume: 5
Pages: e09540
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Publication
12191480 | -
First Author: Hodel AE
Year: 2002
Journal: Mol Cell
Title: The three-dimensional structure of the autoproteolytic, nuclear pore-targeting domain of the human nucleoporin Nup98.
Volume: 10
Issue: 2
Pages: 347-58
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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