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Search results 1 to 100 out of 1420 for Ptk2

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression      
Probe: MGI:6181582
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6191164
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Ptk2
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:6181582
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191164
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Ptk2
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6181582
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191164
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Ptk2
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6181582
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191164
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Ptk2
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6181582
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191164
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Ptk2
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6181582
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191164
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Ptk2
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6181582
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191164
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Ptk2
Detected: true
Specimen Num: 7
Publication
First Author: McGinnis LK
Year: 2015
Journal: Mol Reprod Dev
Title: Role of focal adhesion kinase in oocyte-follicle communication.
Volume: 82
Issue: 2
Pages: 90-102
Publication
First Author: Park AY
Year: 2009
Journal: J Biol Chem
Title: Role of focal adhesion kinase Ser-732 phosphorylation in centrosome function during mitosis.
Volume: 284
Issue: 14
Pages: 9418-25
Publication
First Author: Ilic D
Year: 1995
Journal: Biochem Biophys Res Commun
Title: Focal adhesion kinase is not essential for in vitro and in vivo differentiation of ES cells.
Volume: 209
Issue: 1
Pages: 300-9
Publication
First Author: Tavora B
Year: 2014
Journal: Nature
Title: Endothelial-cell FAK targeting sensitizes tumours to DNA-damaging therapy.
Volume: 514
Issue: 7520
Pages: 112-6
Publication  
First Author: Kostourou V
Year: 2013
Journal: Nat Commun
Title: FAK-heterozygous mice display enhanced tumour angiogenesis.
Volume: 4
Pages: 2020
Publication    
First Author: Olivera GC
Year: 2021
Journal: Elife
Title: Blood-brain barrier-restricted translocation of Toxoplasma gondii from cortical capillaries.
Volume: 10
Publication
First Author: Ma H
Year: 2010
Journal: J Am Soc Nephrol
Title: Inhibition of podocyte FAK protects against proteinuria and foot process effacement.
Volume: 21
Issue: 7
Pages: 1145-56
Publication
First Author: Schober M
Year: 2007
Journal: J Cell Biol
Title: Focal adhesion kinase modulates tension signaling to control actin and focal adhesion dynamics.
Volume: 176
Issue: 5
Pages: 667-80
Publication
First Author: Manso AM
Year: 2009
Journal: Am J Physiol Heart Circ Physiol
Title: Cardiac fibroblasts require focal adhesion kinase for normal proliferation and migration.
Volume: 296
Issue: 3
Pages: H627-38
Publication
First Author: Lee J
Year: 2010
Journal: Cancer Res
Title: Conditional deletion of the focal adhesion kinase FAK alters remodeling of the blood-brain barrier in glioma.
Volume: 70
Issue: 24
Pages: 10131-40
Publication
First Author: Roberts E
Year: 2022
Journal: Vasc Biol
Title: Cell contractility and focal adhesion kinase control circumferential arterial stiffness.
Volume: 4
Issue: 1
Pages: 28-39
Publication
First Author: Tilghman RW
Year: 2005
Journal: J Cell Sci
Title: Focal adhesion kinase is required for the spatial organization of the leading edge in migrating cells.
Volume: 118
Issue: Pt 12
Pages: 2613-23
Publication
First Author: Glodek AM
Year: 2007
Journal: Leukemia
Title: Focal adhesion kinase is required for CXCL12-induced chemotactic and pro-adhesive responses in hematopoietic precursor cells.
Volume: 21
Issue: 8
Pages: 1723-32
Publication
First Author: Hayasaka H
Year: 2007
Journal: J Cell Biochem
Title: Disruption of FRNK expression by gene targeting of the intronic promoter within the focal adhesion kinase gene.
Volume: 102
Issue: 4
Pages: 947-54
Publication
First Author: Ding Q
Year: 2008
Journal: J Biol Chem
Title: Focal adhesion kinase (FAK)-related non-kinase inhibits myofibroblast differentiation through differential MAPK activation in a FAK-dependent manner.
Volume: 283
Issue: 40
Pages: 26839-49
Publication
First Author: Ding Q
Year: 2013
Journal: Am J Pathol
Title: FAK-related nonkinase is a multifunctional negative regulator of pulmonary fibrosis.
Volume: 182
Issue: 5
Pages: 1572-84
Publication
First Author: Tavora B
Year: 2010
Journal: EMBO Mol Med
Title: Endothelial FAK is required for tumour angiogenesis.
Volume: 2
Issue: 12
Pages: 516-28
Publication
First Author: McLean GW
Year: 2001
Journal: Cancer Res
Title: Decreased focal adhesion kinase suppresses papilloma formation during experimental mouse skin carcinogenesis.
Volume: 61
Issue: 23
Pages: 8385-9
Publication
First Author: Vial D
Year: 2003
Journal: J Immunol
Title: Alterations in granule matrix and cell surface of focal adhesion kinase-deficient mast cells.
Volume: 171
Issue: 11
Pages: 6178-86
Publication
First Author: Luo M
Year: 2009
Journal: Cancer Res
Title: Mammary epithelial-specific ablation of the focal adhesion kinase suppresses mammary tumorigenesis by affecting mammary cancer stem/progenitor cells.
Volume: 69
Issue: 2
Pages: 466-74
Publication
First Author: Haemmerle M
Year: 2016
Journal: J Clin Invest
Title: FAK regulates platelet extravasation and tumor growth after antiangiogenic therapy withdrawal.
Volume: 126
Issue: 5
Pages: 1885-96
Publication
First Author: Cai EP
Year: 2012
Journal: Diabetes
Title: In vivo role of focal adhesion kinase in regulating pancreatic β-cell mass and function through insulin signaling, actin dynamics, and granule trafficking.
Volume: 61
Issue: 7
Pages: 1708-18
Publication
First Author: Vemula S
Year: 2010
Journal: Blood
Title: Essential role for focal adhesion kinase in regulating stress hematopoiesis.
Volume: 116
Issue: 20
Pages: 4103-15
Publication
First Author: McLean GW
Year: 2004
Journal: Genes Dev
Title: Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression.
Volume: 18
Issue: 24
Pages: 2998-3003
Publication
First Author: Alexopoulou AN
Year: 2017
Journal: J Pathol
Title: Focal Adhesion Kinase (FAK) tyrosine 397E mutation restores the vascular leakage defect in endothelium-specific FAK-kinase dead mice.
Volume: 242
Issue: 3
Pages: 358-370
Publication
First Author: Li XY
Year: 2011
Journal: J Cell Biol
Title: Snail1 controls epithelial-mesenchymal lineage commitment in focal adhesion kinase-null embryonic cells.
Volume: 195
Issue: 5
Pages: 729-38
Publication
First Author: Pylayeva Y
Year: 2009
Journal: J Clin Invest
Title: Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling.
Volume: 119
Issue: 2
Pages: 252-66
Publication
First Author: Provenzano PP
Year: 2008
Journal: Am J Pathol
Title: Mammary epithelial-specific disruption of focal adhesion kinase retards tumor formation and metastasis in a transgenic mouse model of human breast cancer.
Volume: 173
Issue: 5
Pages: 1551-65
Publication
First Author: Jean C
Year: 2014
Journal: J Cell Biol
Title: Inhibition of endothelial FAK activity prevents tumor metastasis by enhancing barrier function.
Volume: 204
Issue: 2
Pages: 247-63
Publication
First Author: Lechertier T
Year: 2020
Journal: Nat Commun
Title: Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth.
Volume: 11
Issue: 1
Pages: 2810
Publication
First Author: Wheaton AK
Year: 2017
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Lung epithelial cell focal adhesion kinase signaling inhibits lung injury and fibrosis.
Volume: 312
Issue: 5
Pages: L722-L730
Publication
First Author: Owen KA
Year: 2011
Journal: PLoS One
Title: FAK regulates intestinal epithelial cell survival and proliferation during mucosal wound healing.
Volume: 6
Issue: 8
Pages: e23123
Publication
First Author: Essayem S
Year: 2006
Journal: Oncogene
Title: Hair cycle and wound healing in mice with a keratinocyte-restricted deletion of FAK.
Volume: 25
Issue: 7
Pages: 1081-9
Publication
First Author: Shelef MA
Year: 2014
Journal: Arthritis Res Ther
Title: Focal adhesion kinase is required for synovial fibroblast invasion, but not murine inflammatory arthritis.
Volume: 16
Issue: 5
Pages: 464
Publication  
First Author: Shang N
Year: 2016
Journal: Sci Rep
Title: FAK deletion accelerates liver regeneration after two-thirds partial hepatectomy.
Volume: 6
Pages: 34316
Publication  
First Author: Jia C
Year: 2024
Journal: Neurobiol Stress
Title: Astrocyte focal adhesion kinase reduces passive stress coping by inhibiting ciliary neurotrophic factor only in female mice.
Volume: 30
Pages: 100621
Publication
First Author: Dahiya S
Year: 2024
Journal: Nat Commun
Title: Acinar to β-like cell conversion through inhibition of focal adhesion kinase.
Volume: 15
Issue: 1
Pages: 3740
Publication
First Author: Qin Y
Year: 2011
Journal: Am J Pathol
Title: Focal adhesion kinase signaling mediates acute renal injury induced by ischemia/reperfusion.
Volume: 179
Issue: 6
Pages: 2766-78
Publication
First Author: Heim JB
Year: 2018
Journal: PLoS One
Title: FAK auto-phosphorylation site tyrosine 397 is required for development but dispensable for normal skin homeostasis.
Volume: 13
Issue: 7
Pages: e0200558
Publication
First Author: Tavora B
Year: 2014
Journal: Genesis
Title: Generation of point-mutant FAK knockin mice.
Volume: 52
Issue: 11
Pages: 907-15
Publication
First Author: Lahlou H
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Mammary epithelial-specific disruption of the focal adhesion kinase blocks mammary tumor progression.
Volume: 104
Issue: 51
Pages: 20302-7
Publication
First Author: Paul R
Year: 2020
Journal: Breast Cancer Res
Title: FAK activates AKT-mTOR signaling to promote the growth and progression of MMTV-Wnt1-driven basal-like mammary tumors.
Volume: 22
Issue: 1
Pages: 59
Publication
First Author: Luo M
Year: 2013
Journal: Cancer Res
Title: Distinct FAK activities determine progenitor and mammary stem cell characteristics.
Volume: 73
Issue: 17
Pages: 5591-602
Publication
First Author: Chen XL
Year: 2012
Journal: Dev Cell
Title: VEGF-induced vascular permeability is mediated by FAK.
Volume: 22
Issue: 1
Pages: 146-57
Publication
First Author: Castillo AB
Year: 2012
Journal: PLoS One
Title: Focal adhesion kinase plays a role in osteoblast mechanotransduction in vitro but does not affect load-induced bone formation in vivo.
Volume: 7
Issue: 9
Pages: e43291
Publication
First Author: Kim JB
Year: 2007
Journal: Bone
Title: Reconciling the roles of FAK in osteoblast differentiation, osteoclast remodeling, and bone regeneration.
Volume: 41
Issue: 1
Pages: 39-51
Publication
First Author: Lahlou H
Year: 2012
Journal: Breast Cancer Res
Title: Focal adhesion kinase contributes to proliferative potential of ErbB2 mammary tumour cells but is dispensable for ErbB2 mammary tumour induction in vivo.
Volume: 14
Issue: 1
Pages: R36
Publication
First Author: Kasorn A
Year: 2009
Journal: J Immunol
Title: Focal adhesion kinase regulates pathogen-killing capability and life span of neutrophils via mediating both adhesion-dependent and -independent cellular signals.
Volume: 183
Issue: 2
Pages: 1032-43
Publication
First Author: Owen KA
Year: 2007
Journal: J Cell Biol
Title: Regulation of lamellipodial persistence, adhesion turnover, and motility in macrophages by focal adhesion kinase.
Volume: 179
Issue: 6
Pages: 1275-87
Publication  
First Author: Serrels B
Year: 2017
Journal: Sci Signal
Title: IL-33 and ST2 mediate FAK-dependent antitumor immune evasion through transcriptional networks.
Volume: 10
Issue: 508
Publication  
First Author: Weng Y
Year: 2020
Journal: JCI Insight
Title: Liver epithelial focal adhesion kinase modulates fibrogenesis and hedgehog signaling.
Volume: 5
Issue: 20
Publication
First Author: Fiedorek FT Jr
Year: 1995
Journal: Mamm Genome
Title: Mapping of the focal adhesion kinase (Fadk) gene to mouse chromosome 15 and human chromosome 8.
Volume: 6
Issue: 2
Pages: 123-6
Publication  
First Author: Jia C
Year: 2020
Journal: Exp Neurol
Title: Vitronectin mitigates stroke-increased neurogenesis only in female mice and through FAK-regulated IL-6.
Volume: 323
Pages: 113088
Publication
First Author: Jia C
Year: 2022
Journal: J Cereb Blood Flow Metab
Title: Female-specific neuroprotection after ischemic stroke by vitronectin-focal adhesion kinase inhibition.
Volume: 42
Issue: 10
Pages: 1961-1974
Publication
First Author: Kanazawa S
Year: 1996
Journal: Blood
Title: p59fyn-p125FAK cooperation in development of CD4+CD8+ thymocytes.
Volume: 87
Issue: 3
Pages: 865-70
Publication
First Author: Ilić D
Year: 2004
Journal: J Cell Sci
Title: FAK promotes organization of fibronectin matrix and fibrillar adhesions.
Volume: 117
Issue: Pt 2
Pages: 177-87
Publication      
First Author: Mui KL
Year: 2015
Journal: Cell Rep
Title: N-Cadherin Induction by ECM Stiffness and FAK Overrides the Spreading Requirement for Proliferation of Vascular Smooth Muscle Cells.
Publication  
First Author: He Y
Year: 2017
Journal: Genesis
Title: Male germline recombination of a conditional allele by the widely used Dermo1-cre (Twist2-cre) transgene.
Volume: 55
Issue: 9
Publication
First Author: Lim ST
Year: 2010
Journal: J Biol Chem
Title: Pyk2 inhibition of p53 as an adaptive and intrinsic mechanism facilitating cell proliferation and survival.
Volume: 285
Issue: 3
Pages: 1743-53
Publication
First Author: Ding LY
Year: 2024
Journal: Am J Pathol
Title: Stromal Rigidity Stress Accelerates Pancreatic Intraepithelial Neoplasia Progression and Chromosomal Instability via Nuclear Protein Tyrosine Kinase 2 Localization.
Volume: 194
Issue: 7
Pages: 1346-1373
Publication
First Author: Heim JB
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Myosin-1E interacts with FAK proline-rich region 1 to induce fibronectin-type matrix.
Volume: 114
Issue: 15
Pages: 3933-3938
Publication
First Author: Perricone AJ
Year: 2013
Journal: J Am Heart Assoc
Title: Conditional knockout of myocyte focal adhesion kinase abrogates ischemic preconditioning in adult murine hearts.
Volume: 2
Issue: 5
Pages: e000457
Publication
First Author: Chacón MR
Year: 2012
Journal: Development
Title: Focal adhesion kinase regulates actin nucleation and neuronal filopodia formation during axonal growth.
Volume: 139
Issue: 17
Pages: 3200-10
Publication
First Author: Pedrosa AR
Year: 2019
Journal: Cancer Res
Title: Tumor Angiogenesis Is Differentially Regulated by Phosphorylation of Endothelial Cell Focal Adhesion Kinase Tyrosines-397 and -861.
Volume: 79
Issue: 17
Pages: 4371-4386
Publication  
First Author: Jia C
Year: 2019
Journal: Exp Neurol
Title: Vitronectin from brain pericytes promotes adult forebrain neurogenesis by stimulating CNTF.
Volume: 312
Pages: 20-32
Publication
First Author: Hitchcock IS
Year: 2008
Journal: Blood
Title: Roles of focal adhesion kinase (FAK) in megakaryopoiesis and platelet function: studies using a megakaryocyte lineage specific FAK knockout.
Volume: 111
Issue: 2
Pages: 596-604
Publication
First Author: Lu J
Year: 2012
Journal: Exp Hematol
Title: Fak depletion in both hematopoietic and nonhematopoietic niche cells leads to hematopoietic stem cell expansion.
Volume: 40
Issue: 4
Pages: 307-17.e3
Publication
First Author: Shen CJ
Year: 2011
Journal: Exp Cell Res
Title: Decreased cell adhesion promotes angiogenesis in a Pyk2-dependent manner.
Volume: 317
Issue: 13
Pages: 1860-71
Publication
First Author: Petzold T
Year: 2009
Journal: Am J Physiol Cell Physiol
Title: Focal adhesion kinase modulates activation of NF-kappaB by flow in endothelial cells.
Volume: 297
Issue: 4
Pages: C814-22
Publication
First Author: Weis SM
Year: 2008
Journal: J Cell Biol
Title: Compensatory role for Pyk2 during angiogenesis in adult mice lacking endothelial cell FAK.
Volume: 181
Issue: 1
Pages: 43-50
Publication
First Author: Cai GQ
Year: 2012
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Neuronal Wiskott-Aldrich syndrome protein (N-WASP) is critical for formation of α-smooth muscle actin filaments during myofibroblast differentiation.
Volume: 303
Issue: 8
Pages: L692-702
Publication
First Author: Furuta Y
Year: 1995
Journal: Oncogene
Title: Mesodermal defect in late phase of gastrulation by a targeted mutation of focal adhesion kinase, FAK.
Volume: 11
Issue: 10
Pages: 1989-95
Publication
First Author: O'Neill TJ 4th
Year: 2012
Journal: J Mol Cell Cardiol
Title: Germline deletion of FAK-related non-kinase delays post-natal cardiomyocyte mitotic arrest.
Volume: 53
Issue: 2
Pages: 156-64
Publication
First Author: Schmidt TT
Year: 2013
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Conditional deletion of FAK in mice endothelium disrupts lung vascular barrier function due to destabilization of RhoA and Rac1 activities.
Volume: 305
Issue: 4
Pages: L291-300
Publication
First Author: Ilic D
Year: 2003
Journal: Circ Res
Title: Focal adhesion kinase is required for blood vessel morphogenesis.
Volume: 92
Issue: 3
Pages: 300-7
Publication
First Author: Jia C
Year: 2018
Journal: Glia
Title: Inhibition of astrocyte FAK-JNK signaling promotes subventricular zone neurogenesis through CNTF.
Volume: 66
Issue: 11
Pages: 2456-2469
Publication
First Author: Bhavaraju K
Year: 2011
Journal: PLoS One
Title: G(12/13) signaling pathways substitute for integrin αIIbβ3-signaling for thromboxane generation in platelets.
Volume: 6
Issue: 2
Pages: e16586
Publication
First Author: Hiratsuka S
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Endothelial focal adhesion kinase mediates cancer cell homing to discrete regions of the lungs via E-selectin up-regulation.
Volume: 108
Issue: 9
Pages: 3725-30
Publication
First Author: Yurdagul A Jr
Year: 2016
Journal: J Cell Sci
Title: Oxidized LDL induces FAK-dependent RSK signaling to drive NF-κB activation and VCAM-1 expression.
Volume: 129
Issue: 8
Pages: 1580-91
Publication
First Author: Sun S
Year: 2018
Journal: Sci Rep
Title: Nuclear FAK and its kinase activity regulate VEGFR2 transcription in angiogenesis of adult mice.
Volume: 8
Issue: 1
Pages: 2550
Publication
First Author: Watanabe F
Year: 2008
Journal: Eur J Neurosci
Title: Effects of FAK ablation on cerebellar foliation, Bergmann glia positioning and climbing fiber territory on Purkinje cells.
Volume: 27
Issue: 4
Pages: 836-54
Publication
First Author: Wong VW
Year: 2011
Journal: Nat Med
Title: Focal adhesion kinase links mechanical force to skin fibrosis via inflammatory signaling.
Volume: 18
Issue: 1
Pages: 148-52
Publication
First Author: Fan H
Year: 2013
Journal: J Biol Chem
Title: Function of focal adhesion kinase scaffolding to mediate endophilin A2 phosphorylation promotes epithelial-mesenchymal transition and mammary cancer stem cell activities in vivo.
Volume: 288
Issue: 5
Pages: 3322-33
Publication
First Author: You D
Year: 2015
Journal: Cell Rep
Title: FAK mediates a compensatory survival signal parallel to PI3K-AKT in PTEN-null T-ALL cells.
Volume: 10
Issue: 12
Pages: 2055-68