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Search results 2701 to 2800 out of 2826 for Rag1

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Type Details Score
Genotype
Genotype
Symbol: Ifngr1/Ifngr1 Rag1/Rag1 Tg(EIIa-cre)C5379Lmgd/?
Background: involves: 129S7/SvEvBrd * C57BL/6J * C57BL/6NTac * FVB/N * NOD/ShiLtJ
Zygosity: cn
Has Mutant Allele: true
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Publication
12817750 | J:111463
First Author: Mirosavljevic D
Year: 2003
Journal: J Bone Miner Res
Title: T-cells mediate an inhibitory effect of interleukin-4 on osteoclastogenesis.
Volume: 18
Issue: 6
Pages: 984-93
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Publication
31630621 | J:298452
First Author: Lu X
Year: 2019
Journal: Circ Res
Title: A20 in Myeloid Cells Protects Against Hypertension by Inhibiting Dendritic Cell-Mediated T-Cell Activation.
Volume: 125
Issue: 12
Pages: 1055-1066
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Publication
14687938 | J:87913
First Author: Shockett PE
Year: 2004
Journal: Mol Immunol
Title: Partial reconstitution of V(D)J rearrangement and lymphocyte development in RAG-deficient mice expressing inducible, tetracycline-regulated RAG transgenes.
Volume: 40
Issue: 11
Pages: 813-29
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Publication
17069800 | J:123183
First Author: Rohrer B
Year: 2007
Journal: Exp Eye Res
Title: Classical complement activation and acquired immune response pathways are not essential for retinal degeneration in the rd1 mouse.
Volume: 84
Issue: 1
Pages: 82-91
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Publication
29403497 | J:274165
 
First Author: Chyuan IT
Year: 2018
Journal: Front Immunol
Title: TRAIL-Mediated Suppression of T Cell Receptor Signaling Inhibits T Cell Activation and Inflammation in Experimental Autoimmune Encephalomyelitis.
Volume: 9
Pages: 15
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Publication
26818761 | J:318319
First Author: Monteleone I
Year: 2016
Journal: J Crohns Colitis
Title: Smad7 Knockdown Restores Aryl Hydrocarbon Receptor-mediated Protective Signals in the Gut.
Volume: 10
Issue: 6
Pages: 670-7
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Publication
38187389 | J:344460
 
First Author: Roland MM
Year: 2023
Journal: Front Immunol
Title: B-cell-specific MhcII regulates microbiota composition in a primarily IgA-independent manner.
Volume: 14
Pages: 1253674
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Publication
11961538 | -
First Author: Fugmann SD
Year: 2002
Journal: Nature
Title: DNA repair: breaking the seal.
Volume: 416
Issue: 6882
Pages: 691-4
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Protein Domain
IPR004321 | RAG2
Type: Family
Description: The variable portion of the genes encoding immunoglobulins and T cell receptors are assembled from component V, D, and J DNA segments by a site-specific recombination reaction termed V(D)J recombination. V(D)J recombination is targeted to specific sites on the chromosome by recombination signal sequences (RSSs) that flank antigen receptor gene segments. The RSS consists of a conserved heptamer (consensus, 5'-CACAGTG-3') and nonamer (consensus, 5'-ACAAAAACC-3') separated by a spacer of either 12 or 23 bp. Efficient recombination occurs between a 12-RSS and a 23-RSS, a restriction known as the 12/23 rule.V(D)J recombination can be divided into two phases, DNA cleavage and DNA joining. DNA cleavage requires two lymphocyte-specific factors, theproducts of the recombination activating genes, RAG1 and RAG2, which together recognise the RSSs and create double strand breaks at the RSS-coding segment junctions []. RAG-mediated DNA cleavage occurs in a synaptic complex termed the paired complex, which is constituted from two distinct RSS-RAG complexes, a 12-SC and a 23-SC (where SC stands for signal complex). The DNA cleavage reaction involves two distinct enzymatic steps, initial nicking that creates a 3'-OH between a coding segment and its RSS, followed by hairpin formation in which the newly created 3'-OH attacks a phosphodiester bond on the opposite DNA strand. This generates ablunt, 5' phosphorylated signal end containing all of the RSS elements, and a covalently sealed hairpin coding end. The second phase of V(D)J recombination, in which broken DNA fragments are processed and joined, is less well characterised. Signal ends are typically joinedprecisely to form a signal joint, whereas joining of the coding ends requires the hairpin structure to be opened and typically involves nucleotide addition and deletionbefore formation of the coding joint. The factors involved in these processes include ubiquitously expressed proteins involved in the repair of DNA double strandbreaks by nonhomologous end joining, terminal deoxynucleotidyl transferase, and Artemis protein.In addition to their critical roles in RSS recognition and DNA cleavage, the RAG proteins may perform two distinct types of functions in thepostcleavage phase of V(D)J. A structural function has been inferredfrom the finding that, after DNA cleavage in vitro, the DNA ends remain associated with the RAG proteins in a "four end"complex known as the cleaved signalcomplex. After release of the coding ends in vitro, and after coding joint formation in vivo, the RAG proteins remain in astable signal end complex (SEC) containing the two signal ends. These postcleavage complexes may serveas essential scaffolds for the second phase of the reaction, with the RAG proteins acting to organise the DNA processing and joining events. The second type of RAG protein-mediated postcleavage activity is the catalysis of phosphodiester bond hydrolysis and strand transfer reactions. The RAG proteins are capable of opening hairpin coding ends in vitro. The RAG proteinsalso show 3' flap endonuclease activity that may contribute to coding end processing/joining and can utilise the3' OH group on the signal ends to attack hairpin coding ends (forming hybrid or open/shut joints) or virtually any DNA duplex (forming a transposition product).
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Publication
33207189 | J:301684
First Author: Verheijen M
Year: 2020
Journal: Cell Rep
Title: Fate Mapping Quantifies the Dynamics of B Cell Development and Activation throughout Life.
Volume: 33
Issue: 7
Pages: 108376
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Strain
MGI:3623428 | NOD.Cg-Rag1<tm1Mom> H2-Ab1<b-tm1Gru> Tg(HLA-DQA1,HLA-DQB1)1Dv
Attribute String: transgenic, targeted mutation, mutant strain, congenic
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Strain
MGI:3759986 | NOD.Cg-Rag1<tm1Mom> H2-Ab1<b-tm1Gru> Tg(CD4,HLA-DQA1,HLA-DQB1)N8Ell/EllJ
Attribute String: congenic, mutant strain, targeted mutation, transgenic
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Strain
MGI:3687219 | NOD.Cg-Rag1<tm1Mom> H2-Ab1<b-tm1Gru> Tg(HLA-DQA1,HLA-DQB1)73Myl
Attribute String: congenic, mutant strain, targeted mutation, transgenic
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Publication
25482559 | J:222661
First Author: Korn LL
Year: 2014
Journal: Cell Rep
Title: Regulatory T cells occupy an isolated niche in the intestine that is antigen independent.
Volume: 9
Issue: 5
Pages: 1567-73
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Strain
MGI:5882091 | NOD.Cg-Rag1<tm1Mom> Kit<W-41J> Il2rg<tm1Wjl>/EavJ
Attribute String: congenic, mutant strain, spontaneous mutation, targeted mutation
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Strain
MGI:6199071 | B6.129S-Rag1<tm1Mom> Cd47<tm1Fpl> Il2rg<tm1Wjl>/SzJ
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:5902130 | NOD.Cg-Rag1<tm1Mom> Sgca<tm1Kcam> Il2rg<tm1Wjl>/McalJ
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:5566536 | NOD.Cg-Rag1<tm1Mom> Il2rg<tm1Wjl> Tg(CMV-IL3,CSF2,KITLG)1Eav/J
Attribute String: congenic, mutant strain, targeted mutation, transgenic
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Strain
MGI:5812278 | NOD.Cg-Rag1<tm1Mom> Dysf<prmd> Il2rg<tm1Wjl>/McalJ
Attribute String: congenic, mutant strain, spontaneous mutation, targeted mutation
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Strain
MGI:5576367 | B6.Cg-Rag1<tm1Mom> Thy1<a> Tg(CD2-Tcra,Cd4-Tcrb)4CKang/Mmucd
Attribute String: targeted mutation, transgenic, mutant strain, congenic
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Publication
17277104 | J:144001
First Author: Schwarz BA
Year: 2007
Journal: J Immunol
Title: Selective thymus settling regulated by cytokine and chemokine receptors.
Volume: 178
Issue: 4
Pages: 2008-17
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Strain
MGI:3845212 | B6.Cg-Rag1<tm1Mom> Tg(Tcra,Tcrb)HRCAll
Attribute String: congenic, targeted mutation, transgenic
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Strain
MGI:3826840 | B6.Cg-Rag1<tm1Mom> Tyrp1<B-w> Tg(Tcra,Tcrb)9Rest/J
Attribute String: targeted mutation, transgenic, congenic, radiation induced mutation
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Publication
22988035 | J:190638
First Author: Romagnoli P
Year: 2012
Journal: J Immunol
Title: The thymic niche does not limit development of the naturally diverse population of mouse regulatory T lymphocytes.
Volume: 189
Issue: 8
Pages: 3831-7
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Strain
MGI:5496429 | B6.Cg-Rag1<tm1Mom> Thy1<a> Tg(Tcra2C,Tcrb2C)1Dlo/J
Attribute String: congenic, targeted mutation, transgenic
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Strain
MGI:2179472 | B6.Cg-Rag1<tm1Mom> Ins2<Akita>/J
Attribute String: congenic, mutant strain, targeted mutation, spontaneous mutation
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Strain
MGI:4948069 | B6.129S7-Mpz<tm1Msch> Rag1<tm1Mom>
Attribute String: targeted mutation, mutant strain, congenic
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Strain
MGI:3850674 | B6.129-Rag1<tm1Mom> Man2a1<tm1Jxm>
Attribute String: congenic, targeted mutation
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Strain
MGI:5298400 | B6.Cg-Rag1<tm1Mom> Fcgrt<tm1Dcr> Tg(CAG-FCGRT)276Dcr/DcrJ
Attribute String: targeted mutation, transgenic, mutant strain, congenic
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Publication
23409179 | J:197200
First Author: Dong J
Year: 2013
Journal: PLoS One
Title: Homeostatic properties and phenotypic maturation of murine CD4+ pre-thymic emigrants in the thymus.
Volume: 8
Issue: 2
Pages: e56378
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Publication
20929851 | J:171734
First Author: Rubtsov YP
Year: 2010
Journal: Science
Title: Stability of the regulatory T cell lineage in vivo.
Volume: 329
Issue: 5999
Pages: 1667-71
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Publication
26762709 | J:264846
First Author: Al-Chami E
Year: 2016
Journal: Aging Cell
Title: Interleukin-21 administration to aged mice rejuvenates their peripheral T-cell pool by triggering de novo thymopoiesis.
Volume: 15
Issue: 2
Pages: 349-60
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Publication
32905761 | J:316002
First Author: Baranek T
Year: 2020
Journal: Cell Rep
Title: High Dimensional Single-Cell Analysis Reveals iNKT Cell Developmental Trajectories and Effector Fate Decision.
Volume: 32
Issue: 10
Pages: 108116
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Genotype
Genotype
Symbol: Rag1/Rag1<+> Tg(LPV-TAg1135)11Tvd/?
Background: involves: 129/Sv * C57BL/6 * DBA/2
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rag1/Rag1 Tg(LPV-TAg1135)11Tvd/?
Background: involves: 129/Sv * C57BL/6 * DBA/2
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Foxp3/? Rag1/Rag1 Tg(TcraTcrb)425Cbn/?
Background: Not Specified
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Igh-J/Igh-J Igk-J/Igk-J Rag1/Rag1 Tg(DO11.10)10Dlo/?
Background: involves: 129S/Sv * BALB/c * C3H * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: H2-Ab1/H2-Ab1 Rag1/Rag1 Tg(HLA-DQA1,HLA-DQB1)73Myl/?
Background: NOD.Cg-Rag1 H2-Ab1 Tg(HLA-DQA1,HLA-DQB1)73Myl
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rag1/Rag2/Rag1/Rag2
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rag1/Rag2/Rag1/Rag2
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rag1/Rag1 Trp53/Trp53 Xrcc5/Xrcc5
Background: involves: 129S7/SvEvBrd * C57BL
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rag1/Rag1 Tyrp1/Tyrp1 Tg(Tcra,Tcrb)9Rest/?
Background: involves: 101/Rl * 129S7/SvEvBrd * C3H/Rl * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rag1/Rag1 Tg(Tcra,Tcrb)HRCAll/?
Background: B6.Cg-Rag1 Tg(Tcra,Tcrb)HRCAll
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Man2a1/Man2a1 Rag1/Rag1
Background: B6.129-Rag1 Man2a1
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Itk/Itk Rag1/Rag1 Tg(Tcra5CC7,Tcrb5CC7)IWep/?
Background: involves: 129 * C57BL/10
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ctla4/Ctla4 Rag1/Rag1 Tg(TcrAND)53Hed/?
Background: involves: 129S/Sv * 129X1/SvJ * C57BL/6 * SJL
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ctla4/Ctla4 Rag1/Rag1 Tg(TcraTcrb)8Rest/?
Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mpz/Mpz<+> Rag1/Rag1
Background: B6.129S7-Mpz Rag1
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pdpn/Pdpn Rag1/Rag1 Tg(Pdgfrb-cre)9Rha/?
Background: involves: 129S7/SvEvBrd * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Col1a1/Col1a1<+> Rag1/Rag1 Tg(KRT5-rtTA)T2D6Sgkd/?
Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ndfip1/Ndfip1 Rag1/Rag1 Tg(TcraTcrb)425Cbn/?
Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * BALB/c * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Publication
30017086 | J:289697
 
First Author: Palmer VL
Year: 2018
Journal: Cell Immunol
Title: IL10 restrains autoreactive B cells in transgenic mice expressing inactive RAG1.
Volume: 331
Pages: 110-120
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Publication
32582171 | J:305352
 
First Author: Boberg E
Year: 2020
Journal: Front Immunol
Title: Interplay Between the IL-33/ST2 Axis and Bone Marrow ILC2s in Protease Allergen-Induced IL-5-Dependent Eosinophilia.
Volume: 11
Pages: 1058
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Protein
Q99NM2
Organism: Mus musculus/domesticus
Length: 148  
Fragment?: true
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Strain
MGI:3652522 | NOD.Cg-Rag1<tm1Mom> H2-Ab1<b-tm1Gru> Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell/EllJ
Attribute String: congenic, mutant strain, targeted mutation, transgenic
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Strain
MGI:3687224 | NOD.Cg-Rag1<tm1Mom> H2-Ab1<b-tm1Gru> Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell
Attribute String: coisogenic, congenic, mutant strain, targeted mutation, transgenic
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Strain
MGI:6194305 | NOD.Cg-Rag1<tm1Mom> Il2rg<tm1Wjl> Tg(SLC10A1)15Mvw/MvwJ
Attribute String: transgenic, mutant strain, congenic, targeted mutation
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Strain
MGI:4947255 | NOD.Cg-Rag1<tm1Mom> Ins2<Akita> Il2rg<tm1Wjl>/SzJ
Attribute String: targeted mutation, spontaneous mutation, mutant strain, congenic
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Strain
MGI:5432483 | NOD.Cg-Rag1<tm1Mom> Il2rg<tm1Wjl> Tg(HLA-DRA,HLA-DRB1*0401)39-2Kito/ScasJ
Attribute String: congenic, mutant strain, targeted mutation, transgenic
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Strain
MGI:6282997 | NOD.Cg-Rag1<tm1Mom> Flt3<tm1Irl> Mcph1<Tg(HLA-A2.1)1Enge> Il2rg<tm1Wjl>/J
Attribute String: congenic, mutant strain, targeted mutation, transgenic
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Strain
MGI:7330119 | NOD.Cg-Rag1<tm1Mom> Prkdc<scid> Il2rg<tm1Wjl> Tg(HLA-A/H2-D/B2M)1Dvs Tg(CMV-IL3,CSF2,KITLG)1Eav
Attribute String: congenic, mutant strain, spontaneous mutation, targeted mutation, transgenic
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Strain
MGI:4834205 | B6.129-Cd247<tm1Lov> Fcer1g<tm1Rav> Rag1<tm1Mom> Tyrobp<tm1.1Viv>/Orl
Attribute String: congenic, mutant strain, targeted mutation
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Publication
12566417 | J:124688
First Author: Guy-Grand D
Year: 2003
Journal: J Exp Med
Title: Extrathymic T cell lymphopoiesis: ontogeny and contribution to gut intraepithelial lymphocytes in athymic and euthymic mice.
Volume: 197
Issue: 3
Pages: 333-41
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Publication
34626548 | J:318010
First Author: Wang Y
Year: 2021
Journal: Immunity
Title: Early developing B cells undergo negative selection by central nervous system-specific antigens in the meninges.
Volume: 54
Issue: 12
Pages: 2784-2794.e6
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Publication
28694386 | J:244426
First Author: White AJ
Year: 2017
Journal: J Exp Med
Title: A type 2 cytokine axis for thymus emigration.
Volume: 214
Issue: 8
Pages: 2205-2216
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Publication
21148799 | J:168782
First Author: Hale JS
Year: 2011
Journal: J Immunol
Title: Bcl-2-interacting mediator of cell death influences autoantigen-driven deletion and TCR revision.
Volume: 186
Issue: 2
Pages: 799-806
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Publication
30962294 | J:274901
First Author: de Pooter RF
Year: 2019
Journal: J Immunol
Title: Cutting Edge: Lymphomyeloid-Primed Progenitor Cell Fates Are Controlled by the Transcription Factor Tal1.
Volume: 202
Issue: 10
Pages: 2837-2842
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Publication
28978470 | J:254861
First Author: Hu Z
Year: 2017
Journal: Cell Rep
Title: CCR7 Modulates the Generation of Thymic Regulatory T Cells by Altering the Composition of the Thymic Dendritic Cell Compartment.
Volume: 21
Issue: 1
Pages: 168-180
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Strain
MGI:6438680 | B6.Cg-Rag1<tm1Mom> Tg(TcraTcrb)1100Mjb/Tac
Attribute String: mutant strain, congenic, targeted mutation, transgenic
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Publication
21873191 | J:176461
First Author: Egawa T
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Transcription factor AP4 modulates reversible and epigenetic silencing of the Cd4 gene.
Volume: 108
Issue: 36
Pages: 14873-8
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Strain
MGI:7572820 | NOD.Cg-Rag1<tm1Mom> Tg(Foxp3-EGFP/cre)1cJbs/J
Attribute String: congenic, mutant strain, targeted mutation, transgenic
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Strain
MGI:3052705 | NOD.Cg-Rag1<tm1Mom> Cd86<tm2Shr> Cd80<tm1Shr>/JbsJ
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:3818080 | NOD.Cg-Rag1<tm1Mom> Ins2<Akita> Prf1<tm1Sdz>
Attribute String: targeted mutation, spontaneous mutation, congenic
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Strain
MGI:3805959 | NOD.Cg-Rag1<tm1Mom> Ins2<Akita> Prf1<tm1Sdz>/SzJ
Attribute String: targeted mutation, spontaneous mutation, congenic
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Strain
MGI:6332510 | B10.Cg-H2<k> Fas<lpr> Rag1<tm1Mom> Tg(TcraKB5.C20,TcrbKB5.C20)10395Arnd/Apb
Attribute String: mutant strain, congenic, targeted mutation, transgenic, spontaneous mutation
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Publication
31792212 | J:286307
First Author: Cowan JE
Year: 2019
Journal: Nat Commun
Title: Myc controls a distinct transcriptional program in fetal thymic epithelial cells that determines thymus growth.
Volume: 10
Issue: 1
Pages: 5498
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Publication
23401586 | J:193683
First Author: Bhaumik S
Year: 2013
Journal: J Immunol
Title: Retinoic acid hypersensitivity promotes peripheral tolerance in recent thymic emigrants.
Volume: 190
Issue: 6
Pages: 2603-13
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Publication
26254339 | J:335281
First Author: McCarthy NI
Year: 2015
Journal: J Immunol
Title: Osteoprotegerin-Mediated Homeostasis of Rank+ Thymic Epithelial Cells Does Not Limit Foxp3+ Regulatory T Cell Development.
Volume: 195
Issue: 6
Pages: 2675-82
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Publication
26832402 | J:269847
First Author: Cowan JE
Year: 2016
Journal: Cell Rep
Title: CCR7 Controls Thymus Recirculation, but Not Production and Emigration, of Foxp3(+) T Cells.
Volume: 14
Issue: 5
Pages: 1041-1048
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Publication
32687059 | J:313536
   
First Author: Peligero-Cruz C
Year: 2020
Journal: Elife
Title: IL18 signaling promotes homing of mature Tregs into the thymus.
Volume: 9
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Publication
29285761 | J:262956
First Author: Cowan JE
Year: 2018
Journal: Eur J Immunol
Title: Aire controls the recirculation of murine Foxp3+ regulatory T-cells back to the thymus.
Volume: 48
Issue: 5
Pages: 844-854
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Publication
23315077 | J:193323
First Author: Nobrega C
Year: 2013
Journal: J Immunol
Title: T cells home to the thymus and control infection.
Volume: 190
Issue: 4
Pages: 1646-58
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Publication
21098226 | J:168007
First Author: Chougnet CA
Year: 2011
Journal: J Immunol
Title: A major role for Bim in regulatory T cell homeostasis.
Volume: 186
Issue: 1
Pages: 156-63
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Publication
31841113 | J:284585
   
First Author: Jimeno R
Year: 2019
Journal: Elife
Title: Tissue-specific shaping of the TCR repertoire and antigen specificity of iNKT cells.
Volume: 8
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Genotype
Genotype
Symbol: Rag1/Rag1 Tg(LPV-TAg1135)11Tvd/? Tg(TcrLCMV)327Sdz/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * DBA/2
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rag1/Rag1<+> Tg(LPV-TAg1135)11Tvd/? Tg(TcrLCMV)327Sdz/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * DBA/2
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: H2-Ab1/H2-Ab1 Rag1/Rag1 Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell/Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell
Background: NOD.Cg-Rag1 H2-Ab1 Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rag1/Rag1 Slc46a2/Slc46a2<+> Tg(TcraB12,TcrbB12)1Rest/?
Background: involves: 129 * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ins2/Ins2<+> Prf1/Prf1 Rag1/Rag1
Background: NOD.Cg-Rag1 Ins2 Prf1
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ins2/Ins2 Prf1/Prf1 Rag1/Rag1
Background: NOD.Cg-Rag1 Ins2 Prf1
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Foxo1/Foxo1 Rag1/Rag1 Tg(Cd4-cre)1Cwi/? Tg(TcraTcrb)425Cbn/?
Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Foxo1/Foxo1 Rag1/Rag1 Tg(CD2-Il7r)1Asin/? Tg(Cd4-cre)1Cwi/? Tg(TcraTcrb)425Cbn/?
Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nlrp3/Nlrp3<+> Rag1/Rag1 Lyz2/Lyz2<+>
Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/? Il5/Il5<+> Rag1/Rag1
Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: H2/H2 Rag1/Rag1 Tg(HLA-DRA,HLA-DRB5*0101)hiKito/? Tg(TRATL3A6,TRBTL3A6)#Kito/?
Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: H2/H2 Rag1/Rag1 Tg(HLA-DRA,HLA-DRB5*0101)loKito/? Tg(TRATL3A6,TRBTL3A6)#Kito/?
Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cmtm7/Cmtm7<+> Rag1/Rag1
Background: chimera involves: C57BL/6 * C57BL/6N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rag1/Rag1 Tg(Foxp3-EGFP/cre)1cJbs/?
Background: NOD.Cg-Rag1 Tg(Foxp3-EGFP/cre)1cJbs/J
Zygosity: cx
Has Mutant Allele: true
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Protein
P21784
Organism: Mus musculus/domesticus
Length: 527  
Fragment?: false
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