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Search results 101 to 200 out of 294 for Rab7

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Type Details Score
Publication
30201994 | J:282504
First Author: Sato R
Year: 2018
Journal: Nat Immunol
Title: Combating herpesvirus encephalitis by potentiating a TLR3-mTORC2 axis.
Volume: 19
Issue: 10
Pages: 1071-1082
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Publication
30135482 | J:266255
First Author: Scavuzzo MA
Year: 2018
Journal: Nat Commun
Title: Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis.
Volume: 9
Issue: 1
Pages: 3356
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Publication
27390154 | J:240360
First Author: Tyrrell BJ
Year: 2016
Journal: Pigment Cell Melanoma Res
Title: Loss of strumpellin in the melanocytic lineage impairs the WASH Complex but does not affect coat colour.
Volume: 29
Issue: 5
Pages: 559-71
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Publication
22698281 | J:184591
First Author: Aoyama M
Year: 2012
Journal: Dev Cell
Title: Spatial restriction of bone morphogenetic protein signaling in mouse gastrula through the mVam2-dependent endocytic pathway.
Volume: 22
Issue: 6
Pages: 1163-75
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Publication
33340069 | J:305611
First Author: Castroflorio E
Year: 2021
Journal: Cell Mol Life Sci
Title: The Ncoa7 locus regulates V-ATPase formation and function, neurodevelopment and behaviour.
Volume: 78
Issue: 7
Pages: 3503-3524
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Publication
27294511 | J:238155
First Author: Safaiyan S
Year: 2016
Journal: Nat Neurosci
Title: Age-related myelin degradation burdens the clearance function of microglia during aging.
Volume: 19
Issue: 8
Pages: 995-8
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Publication
29158485 | J:256230
First Author: Shin SW
Year: 2017
Journal: Nat Commun
Title: Cytoplasmic cleavage of DPPA3 is required for intracellular trafficking and cleavage-stage development in mice.
Volume: 8
Issue: 1
Pages: 1643
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Publication
20943658 | J:167591
First Author: Mayer PR
Year: 2010
Journal: J Biol Chem
Title: Expression, localization, and biochemical characterization of nicotinamide mononucleotide adenylyltransferase 2.
Volume: 285
Issue: 51
Pages: 40387-96
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Publication
24760869 | J:210609
First Author: Yu T
Year: 2014
Journal: J Neurosci
Title: In vivo regulation of NGF-mediated functions by Nedd4-2 ubiquitination of TrkA.
Volume: 34
Issue: 17
Pages: 6098-106
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Publication
19368996 | J:150874
First Author: Tambe Y
Year: 2009
Journal: Cancer Lett
Title: The drs tumor suppressor is involved in the maturation process of autophagy induced by low serum.
Volume: 283
Issue: 1
Pages: 74-83
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Publication
24035762 | J:201826
First Author: Ouyang Q
Year: 2013
Journal: Neuron
Title: Christianson syndrome protein NHE6 modulates TrkB endosomal signaling required for neuronal circuit development.
Volume: 80
Issue: 1
Pages: 97-112
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
32279353 | J:345946
First Author: Sarkar C
Year: 2020
Journal: J Inherit Metab Dis
Title: Cln1-mutations suppress Rab7-RILP interaction and impair autophagy contributing to neuropathology in a mouse model of infantile neuronal ceroid lipofuscinosis.
Volume: 43
Issue: 5
Pages: 1082-1101
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Publication
19509052 | J:153178
First Author: Schaheen B
Year: 2009
Journal: J Cell Sci
Title: Derlin-dependent accumulation of integral membrane proteins at cell surfaces.
Volume: 122
Issue: Pt 13
Pages: 2228-39
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Publication
26582200 | J:230059
First Author: Urresti J
Year: 2016
Journal: J Biol Chem
Title: Lifeguard Inhibits Fas Ligand-mediated Endoplasmic Reticulum-Calcium Release Mandatory for Apoptosis in Type II Apoptotic Cells.
Volume: 291
Issue: 3
Pages: 1221-34
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:72245
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
18656450 | J:139000
First Author: Yuasa K
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Trafficking of cGMP-dependent protein kinase II via interaction with Rab11.
Volume: 374
Issue: 3
Pages: 522-6
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Publication
22467241 | J:211452
First Author: Yang DQ
Year: 2012
Journal: J Bone Miner Res
Title: V-ATPase subunit ATP6AP1 (Ac45) regulates osteoclast differentiation, extracellular acidification, lysosomal trafficking, and protease exocytosis in osteoclast-mediated bone resorption.
Volume: 27
Issue: 8
Pages: 1695-707
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Publication
20004763 | J:158450
First Author: Mochida GH
Year: 2009
Journal: Am J Hum Genet
Title: A truncating mutation of TRAPPC9 is associated with autosomal-recessive intellectual disability and postnatal microcephaly.
Volume: 85
Issue: 6
Pages: 897-902
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Publication
9811942 | J:50869
First Author: Ko MS
Year: 1998
Journal: Hum Mol Genet
Title: Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome.
Volume: 7
Issue: 12
Pages: 1967-78
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Publication
15328023 | J:93154
First Author: Lü J
Year: 2004
Journal: Dev Biol
Title: Global analysis of genes differentially expressed in branching and non-branching regions of the mouse embryonic lung.
Volume: 273
Issue: 2
Pages: 418-35
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Publication
15745951 | J:98595
First Author: Kerns RT
Year: 2005
Journal: J Neurosci
Title: Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice.
Volume: 25
Issue: 9
Pages: 2255-66
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18692022 | J:139565
First Author: Saito F
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Inefficient phagosome maturation in infant macrophages.
Volume: 375
Issue: 1
Pages: 113-8
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
25127994 | J:216175
First Author: Cerqueira DM
Year: 2014
Journal: Dev Biol
Title: Sterol carrier protein 2 regulates proximal tubule size in the Xenopus pronephric kidney by modulating lipid rafts.
Volume: 394
Issue: 1
Pages: 54-64
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Publication
38103552 | J:344234
First Author: Zou W
Year: 2024
Journal: Dev Cell
Title: Lysosomal dynamics regulate mammalian cortical neurogenesis.
Volume: 59
Issue: 1
Pages: 64-78.e5
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Publication
38351062 | J:345844
First Author: Guo Y
Year: 2024
Journal: Signal Transduct Target Ther
Title: Docking protein 6 (DOK6) selectively docks the neurotrophic signaling transduction to restrain peripheral neuropathy.
Volume: 9
Issue: 1
Pages: 32
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GXD Expression
GXD Expression
   
Probe: MGI:7482729
Assay Type: RT-PCR
Annotation Date: 2023-05-22
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:7482764
Age: postnatal adult
Image: S5
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7482729
Assay Type: RT-PCR
Annotation Date: 2023-05-22
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:7482764
Age: postnatal adult
Image: S5
Specimen Label: KO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7482714
Assay Type: Western blot
Annotation Date: 2023-05-22
Strength: Present
Sex: Female
Emaps: EMAPS:3575528
Stage: TS28
Assay Id: MGI:7482783
Age: postnatal adult
Image: 4
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7482714
Assay Type: Western blot
Annotation Date: 2023-05-22
Strength: Present
Sex: Female
Emaps: EMAPS:3575528
Stage: TS28
Assay Id: MGI:7482783
Age: postnatal adult
Image: 4
Specimen Label: KO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6711714
Assay Type: Immunohistochemistry
Annotation Date: 2021-05-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160699
Pattern: Not Specified
Stage: TS09
Assay Id: MGI:6711861
Age: embryonic day 6.5
Image: 3A flox/-
Specimen Label: 3A flox/-
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6711714
Assay Type: Immunohistochemistry
Annotation Date: 2021-05-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160699
Pattern: Not Specified
Stage: TS09
Assay Id: MGI:6711861
Age: embryonic day 6.5
Image: S2A flox/-
Specimen Label: S2A flox/-
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6711714
Assay Type: Immunohistochemistry
Annotation Date: 2021-05-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:160699
Stage: TS09
Assay Id: MGI:6711861
Age: embryonic day 6.5
Image: S2A Sox2-cKO
Specimen Label: S2A Sox2-cKO
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:2465759
Assay Type: RNA in situ
Annotation Date: 2023-08-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7522947
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4844417
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3270519
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:4848379
Age: embryonic day 11.5
Note: Staining is present in the progress zone and middle limb.
Specimen Label: Table S4 - E11.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:3070188
Assay Type: RNA in situ
Annotation Date: 2004-12-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286619
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:3511227
Age: embryonic day 11.5
Image: 2H
Note: Expression restricted to the distal mesenchyme.
Specimen Label: 2H
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6711714
Assay Type: Immunohistochemistry
Annotation Date: 2021-05-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160399
Pattern: Regionally restricted
Stage: TS09
Assay Id: MGI:6711861
Age: embryonic day 6.5
Image: 3A Ttr-cKO
Note: Expression was below detectable levels in the visceral endoderm.
Specimen Label: 3A Ttr-cKO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:2465759
Assay Type: RNA in situ
Annotation Date: 2023-08-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7522947
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6711714
Assay Type: Immunohistochemistry
Annotation Date: 2021-05-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:160519
Stage: TS09
Assay Id: MGI:6711861
Age: embryonic day 6.5
Image: 3A Ttr-cKO
Specimen Label: 3A Ttr-cKO
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7398450
Assay Type: Immunohistochemistry
Annotation Date: 2022-12-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:160519
Pattern: Widespread
Stage: TS09
Assay Id: MGI:7398485
Age: embryonic day 6.5
Image: 4a/c'/c'''
Note: Expression in lysosomal membrane. Faint expression throughout all cells.
Specimen Label: 4a/c'/c'''
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7398450
Assay Type: Immunohistochemistry
Annotation Date: 2022-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160519
Pattern: Regionally restricted
Stage: TS09
Assay Id: MGI:7398485
Age: embryonic day 6.5
Image: 4b/d'/d'''
Note: Expression in large, discrete vesicles primarily in visceral endoderm.
Specimen Label: 4b/d'/d'''
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7398450
Assay Type: Immunohistochemistry
Annotation Date: 2022-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160519
Pattern: Regionally restricted
Stage: TS09
Assay Id: MGI:7398485
Age: embryonic day 6.5
Image: 4e/e''/g
Note: Higher levels of expression in proximal half of visceral endoderm thatn in distal half.
Specimen Label: 4e/e''/g
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:7398450
Assay Type: Immunohistochemistry
Annotation Date: 2022-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160519
Pattern: Regionally restricted
Stage: TS09
Assay Id: MGI:7398485
Age: embryonic day 6.5
Image: 4f/f''/h
Note: Lysosomes disprersed evenly throughout visceral endoderm. No difference between proximal and distal parts. Large discrete patches non-overlapping with Lamp1 expression.
Specimen Label: 4f/f''/h
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:7464561
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160519
Pattern: Punctate
Stage: TS09
Assay Id: MGI:7464737
Age: embryonic day 6.5
Note: Punctate expression localized to apical vacuoles in visceral endoderm.
Specimen Label: 1C WT sagittal
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7464561
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160519
Pattern: Punctate
Stage: TS09
Assay Id: MGI:7464737
Age: embryonic day 6.5
Note: Punctate expression localized to apical vacuoles in visceral endoderm.
Specimen Label: 1C WT parasagittal
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7464561
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160519
Pattern: Regionally restricted
Stage: TS09
Assay Id: MGI:7464737
Age: embryonic day 6.5
Note: Expression frequently decorated entire boundary of spherical structures.
Specimen Label: 1C mVam2-/- sagittal
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:7464561
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160519
Pattern: Regionally restricted
Stage: TS09
Assay Id: MGI:7464737
Age: embryonic day 6.5
Note: Expression frequently decorated entire boundary of spherical structures.
Specimen Label: 1C mVam2-/- parasagittal
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:7464561
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:381337
Pattern: Not Specified
Stage: TS07
Assay Id: MGI:7541126
Age: embryonic day 5.5
Image: 4a/b/c
Note: Appeared as dots in both the apical and basolateral cytoplasm. Often decorated the apical vacuole membranes.
Specimen Label: 4a/b/c
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7464561
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:381337
Pattern: Not Specified
Stage: TS07
Assay Id: MGI:7541126
Age: embryonic day 5.5
Image: 4e/f/g
Note: Increased expression. Abnormal accumulation of positive vesicles was seen.
Specimen Label: 4e/f/g
Detected: true
Specimen Num: 2
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Protein
Q4FJQ0
Organism: Mus musculus/domesticus
Length: 207  
Fragment?: false
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Publication
26100023 | J:228236
First Author: Toyofuku T
Year: 2015
Journal: Mol Cell Biol
Title: Leucine-Rich Repeat Kinase 1 Regulates Autophagy through Turning On TBC1D2-Dependent Rab7 Inactivation.
Volume: 35
Issue: 17
Pages: 3044-58
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Publication
9126495 | J:40089
First Author: Davies JP
Year: 1997
Journal: Genomics
Title: Cloning and mapping of human Rab7 and Rab9 cDNA sequences and identification of a Rab9 pseudogene.
Volume: 41
Issue: 1
Pages: 131-4
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Gene
7879 | RAB7A
Type: gene
Organism: human
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Publication
30717974 | J:291206
First Author: Matsumoto N
Year: 2019
Journal: Biochem Biophys Res Commun
Title: Proton pumping V-ATPase inhibitor bafilomycin A1 affects Rab7 lysosomal localization and abolishes anterograde trafficking of osteoclast secretory lysosomes.
Volume: 510
Issue: 3
Pages: 421-426
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Protein
Q9CXF4
Organism: Mus musculus/domesticus
Length: 671  
Fragment?: false
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Publication
14668488 | J:90032
First Author: Wang T
Year: 2004
Journal: Mol Biol Cell
Title: A unique region of RILP distinguishes it from its related proteins in its regulation of lysosomal morphology and interaction with Rab7 and Rab34.
Volume: 15
Issue: 2
Pages: 815-26
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Publication
22115783 | -
First Author: Lin WJ
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Lysosomal targeting of phafin1 mediated by Rab7 induces autophagosome formation.
Volume: 417
Issue: 1
Pages: 35-42
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Interaction Experiment
Mizuno K (2003)
Description: Rabring7, a novel Rab7 target protein with a RING finger motif.
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DO Term
DOID:0110159 | Charcot-Marie-Tooth disease type 2B
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Publication
24413168 | -
First Author: Cabrera M
Year: 2014
Journal: J Cell Sci
Title: The Mon1-Ccz1 GEF activates the Rab7 GTPase Ypt7 via a longin-fold-Rab interface and association with PI3P-positive membranes.
Volume: 127
Issue: Pt 5
Pages: 1043-51
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Publication
33144569 | -
First Author: van den Boomen DJH
Year: 2020
Journal: Nat Commun
Title: A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export.
Volume: 11
Issue: 1
Pages: 5559
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Allele
Rab7<em1Smoc> | MGI:7291953
Name: RAB7, member RAS oncogene family; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
28325809 | -
First Author: Marwaha R
Year: 2017
Journal: J Cell Biol
Title: The Rab7 effector PLEKHM1 binds Arl8b to promote cargo traffic to lysosomes.
Volume: 216
Issue: 4
Pages: 1051-1070
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GXD Expression
GXD Expression
Probe: MGI:7398451
Assay Type: Immunohistochemistry
Annotation Date: 2022-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160519
Pattern: Regionally restricted
Stage: TS09
Assay Id: MGI:7398486
Age: embryonic day 6.5
Image: 4f/f'''/h
Note: Late endosomes dispersed evenly throughout visceral endoderm with no difference between proximal and distal parts. Large discrete patches non-overlapping with Rab7 expression.
Specimen Label: 4f/f'''/h
Detected: true
Specimen Num: 4
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Publication
12545426 | -
First Author: Verhoeven K
Year: 2003
Journal: Am J Hum Genet
Title: Mutations in the small GTP-ase late endosomal protein RAB7 cause Charcot-Marie-Tooth type 2B neuropathy.
Volume: 72
Issue: 3
Pages: 722-7
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Allele
Gt(ROSA)26Sor<tm1.1(CMV-Rab7)Zmx> | MGI:6448096
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1.1, Zhenming Xu
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence
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Publication
20363736 | -
First Author: Peralta ER
Year: 2010
Journal: J Biol Chem
Title: Differential effects of TBC1D15 and mammalian Vps39 on Rab7 activation state, lysosomal morphology, and growth factor dependence.
Volume: 285
Issue: 22
Pages: 16814-21
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Publication
25999476 | -
First Author: Numrich J
Year: 2015
Journal: J Cell Sci
Title: The I-BAR protein Ivy1 is an effector of the Rab7 GTPase Ypt7 involved in vacuole membrane homeostasis.
Volume: 128
Issue: 13
Pages: 2278-92
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Publication
20100911 | -
First Author: Pankiv S
Year: 2010
Journal: J Cell Biol
Title: FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport.
Volume: 188
Issue: 2
Pages: 253-69
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Strain
MGI:6448097 | B6(Cg)-Gt(ROSA)26Sor<tm1.1(CMV-Rab7)Zmx>/J
Attribute String: mutant strain, targeted mutation
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Protein
F6X2I0
Organism: Mus musculus/domesticus
Length: 141  
Fragment?: true
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Protein
F6RDF1
Organism: Mus musculus/domesticus
Length: 134  
Fragment?: true
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Protein Domain
IPR021563 | RILP_dimer
Type: Domain
Description: Rab interacting lysosomal protein (RILP) contains a domain which contains two coiled-coil regions and is found mainly in the cytosol. RILP is recruited onto late endosomal and lysosomal membranes by Rab7 and acts as a downstream effector of Rab7 []. This recruitment process is important for phagosome maturation and fusion with late endosomes and lysosomes.
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Protein Domain
IPR040371 | RMC1
Type: Family
Description: RMC1 is a componement of the the CCZ1-MON1 complex, which functions as a guanine exchange factor (GEF) for RAB7 during endocytic and autophagic flux to the lysosome. It positively regulates CCZ1-MON1 function that is necessary for endosomal/autophagic flux and efficient RAB7 localization on CD63-positive vesicle membranes [].
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Publication
25498145 | J:219629
First Author: McEwan DG
Year: 2015
Journal: Mol Cell
Title: PLEKHM1 regulates autophagosome-lysosome fusion through HOPS complex and LC3/GABARAP proteins.
Volume: 57
Issue: 1
Pages: 39-54
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Protein
A0A3Q4EGY8
Organism: Mus musculus/domesticus
Length: 121  
Fragment?: true
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Protein
A0A3Q4EBT5
Organism: Mus musculus/domesticus
Length: 131  
Fragment?: true
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Publication
29038162 | -
     
First Author: Pontano Vaites L
Year: 2017
Journal: Mol Cell Biol
Title: Systematic analysis of human cells lacking ATG8 proteins uncovers roles for GABARAPs and the CCZ1/MON1 regulator C18orf8/RMC1 in macro and selective autophagic flux.
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Publication
11856727 | J:83919
First Author: Fukuda M
Year: 2002
Journal: J Biol Chem
Title: Slac2-a/melanophilin, the missing link between Rab27 and myosin Va: implications of a tripartite protein complex for melanosome transport.
Volume: 277
Issue: 14
Pages: 12432-6
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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