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Search results 101 to 170 out of 170 for Caml

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:971964
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823608
Age: embryonic day 14.5
Image: euxassay_001896_15
Specimen Label: euxassay_001896_15
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:971964
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823608
Age: embryonic day 14.5
Image: euxassay_001896_16
Specimen Label: euxassay_001896_16
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
 
Probe: MGI:971964
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823608
Age: embryonic day 14.5
Image: euxassay_001896_17
Specimen Label: euxassay_001896_17
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
 
Probe: MGI:971964
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823608
Age: embryonic day 14.5
Image: euxassay_001896_18
Specimen Label: euxassay_001896_18
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
 
Probe: MGI:971964
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823608
Age: embryonic day 14.5
Image: euxassay_001896_19
Specimen Label: euxassay_001896_19
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
 
Probe: MGI:4884273
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945748
Age: postnatal day 7
Image: g01425 P7
Specimen Label: g01425 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4884273
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945748
Age: postnatal day 42
Image: g01425 Adult
Specimen Label: g01425 Adult
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:4884273
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280923
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945748
Age: embryonic day 15.5
Image: g01425 E15.5
Specimen Label: g01425 E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:4884273
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945748
Age: postnatal day 7
Image: g01425 P7
Note: Expression was region specific and scattered.
Specimen Label: g01425 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4884273
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945748
Age: postnatal day 42
Image: g01425 Adult
Specimen Label: g01425 Adult
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:4884273
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266523
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945748
Age: embryonic day 15.5
Image: g01425 E15.5
Specimen Label: g01425 E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4884273
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945748
Age: embryonic day 15.5
Image: g01425 E15.5
Specimen Label: g01425 E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4884273
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945748
Age: postnatal day 7
Image: g01425 P7
Specimen Label: g01425 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4884273
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945748
Age: postnatal day 42
Image: g01425 Adult
Specimen Label: g01425 Adult
Detected: true
Specimen Num: 4
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:67690
   
First Author: Morales VM
Year: 1998
Journal: GenBank Submission
Title: Mus musculus calcium signal-modulating ligand (Camlg) gene, promoter region and partial cds; unknown genes
Pages: AF078112
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Protein
P49070
Organism: Mus musculus/domesticus
Length: 294  
Fragment?: false
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Protein
Q9ET35
Organism: Mus musculus/domesticus
Length: 249  
Fragment?: false
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Publication
10920230 | J:63698
First Author: von Bülow GU
Year: 2000
Journal: Mamm Genome
Title: Molecular cloning and functional characterization of murine transmembrane activator and CAML interactor (TACI) with chromosomal localization in human and mouse.
Volume: 11
Issue: 8
Pages: 628-32
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Allele
Caml<em1Smoc> | MGI:7288625
Name: calcium modulating ligand; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
24392163 | -
First Author: Vilardi F
Year: 2014
Journal: PLoS One
Title: WRB and CAML are necessary and sufficient to mediate tail-anchored protein targeting to the ER membrane.
Volume: 9
Issue: 1
Pages: e85033
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Gene
23495 | TNFRSF13B
Type: gene
Organism: human
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DO Term
DOID:0081145 | common variable immunodeficiency 2
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Publication
29133782 | J:257210
First Author: Sintes J
Year: 2017
Journal: Nat Commun
Title: mTOR intersects antibody-inducing signals from TACI in marginal zone B cells.
Volume: 8
Issue: 1
Pages: 1462
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Publication
21984806 | J:178849
First Author: Tsuji S
Year: 2011
Journal: Blood
Title: TACI deficiency impairs sustained Blimp-1 expression in B cells decreasing long-lived plasma cells in the bone marrow.
Volume: 118
Issue: 22
Pages: 5832-9
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Publication
17492055 | J:122090
First Author: Garibyan L
Year: 2007
Journal: J Clin Invest
Title: Dominant-negative effect of the heterozygous C104R TACI mutation in common variable immunodeficiency (CVID).
Volume: 117
Issue: 6
Pages: 1550-7
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Publication
27022196 | J:318410
First Author: Jacobs HM
Year: 2016
Journal: J Immunol
Title: Cutting Edge: BAFF Promotes Autoantibody Production via TACI-Dependent Activation of Transitional B Cells.
Volume: 196
Issue: 9
Pages: 3525-31
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Publication
7522304 | -
First Author: Bram RJ
Year: 1994
Journal: Nature
Title: Calcium signalling in T cells stimulated by a cyclophilin B-binding protein.
Volume: 371
Issue: 6495
Pages: 355-8
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Publication
23041287 | -
First Author: Yamamoto Y
Year: 2012
Journal: Mol Cell
Title: Molecular machinery for insertion of tail-anchored membrane proteins into the endoplasmic reticulum membrane in mammalian cells.
Volume: 48
Issue: 3
Pages: 387-97
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Publication
32187542 | -
First Author: Inglis AJ
Year: 2020
Journal: Cell Rep
Title: Differential Modes of Orphan Subunit Recognition for the WRB/CAML Complex.
Volume: 30
Issue: 11
Pages: 3691-3698.e5
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Publication
27226539 | -
First Author: Colombo SF
Year: 2016
Journal: J Biol Chem
Title: Tail-anchored Protein Insertion in Mammals: FUNCTION AND RECIPROCAL INTERACTIONS OF THE TWO SUBUNITS OF THE TRC40 RECEPTOR.
Volume: 291
Issue: 29
Pages: 15292-306
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Publication
25869254 | -
First Author: Yamamoto Y
Year: 2015
Journal: J Biochem
Title: The emerging role of calcium-modulating cyclophilin ligand in posttranslational insertion of tail-anchored proteins into the endoplasmic reticulum membrane.
Volume: 157
Issue: 6
Pages: 419-29
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Protein Domain
IPR016719 | CAMLG
Type: Family
Description: This entry represents the Guided entry of tail-anchored proteins factor CAMLG (also known as Calcium signal-modulating cyclophilin ligand CAML) which is required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum [, , ]. Together with GET1/WRB, acts as a membrane receptor for soluble GET3/TRC40, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol [, , ]. It is required for the stability of GET1 []. CAMLG also stimulates calcium signaling in T cells through its involvement in elevation of intracellular calcium [], and it is essential for the survival of peripheral follicular B cells. Although CAML shows no sequence similarity to yeast Get2, they share similar biochemical properties and topology [], thus resulting in the Get2 homologue in mammals, playing the same essential role in the membrane insertion as that of Get2. It also shows similarity with ER membrane protein complex subunit 6 (EMC6) [].
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Publication
34509440 | J:312953
     
First Author: Spinosa MD
Year: 2021
Journal: Am J Pathol
Title: B Cell-Activating Factor Antagonism Attenuates the Growth of Experimental Abdominal Aortic Aneurysm.
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Publication
17369193 | J:120118
First Author: Hondowicz BD
Year: 2007
Journal: Int Immunol
Title: The role of BLyS/BLyS receptors in anti-chromatin B cell regulation.
Volume: 19
Issue: 4
Pages: 465-75
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Publication
16791880 | J:115788
First Author: Ng LG
Year: 2006
Journal: Eur J Immunol
Title: BAFF costimulation of Toll-like receptor-activated B-1 cells.
Volume: 36
Issue: 7
Pages: 1837-46
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Publication
14768056 | J:87673
First Author: Tardivel A
Year: 2004
Journal: Eur J Immunol
Title: The anti-apoptotic factor Bcl-2 can functionally substitute for the B cell survival but not for the marginal zone B cell differentiation activity of BAFF.
Volume: 34
Issue: 2
Pages: 509-18
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Publication
28267197 | J:246255
First Author: Tran NL
Year: 2017
Journal: Eur J Immunol
Title: TACI-dependent APRIL signaling maintains autoreactive B cells in a mouse model of systemic lupus erythematosus.
Volume: 47
Issue: 4
Pages: 713-723
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Publication
17357108 | J:120803
First Author: Acosta-Rodríguez EV
Year: 2007
Journal: Eur J Immunol
Title: BAFF and LPS cooperate to induce B cells to become susceptible to CD95/Fas-mediated cell death.
Volume: 37
Issue: 4
Pages: 990-1000
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Publication
34111031 | J:313013
 
First Author: Platt JL
Year: 2021
Journal: JCI Insight
Title: TNFRSF13B polymorphisms counter microbial adaptation to enteric IgA.
Volume: 6
Issue: 14
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Protein
B1ATI3
Organism: Mus musculus/domesticus
Length: 73  
Fragment?: true
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Protein
Q3U2P4
Organism: Mus musculus/domesticus
Length: 143  
Fragment?: true
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Publication
10801128 | J:61942
First Author: Gross JA
Year: 2000
Journal: Nature
Title: TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease.
Volume: 404
Issue: 6781
Pages: 995-9
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Publication
16007086 | -
First Author: Castigli E
Year: 2005
Journal: Nat Genet
Title: TACI is mutant in common variable immunodeficiency and IgA deficiency.
Volume: 37
Issue: 8
Pages: 829-34
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Protein Domain
IPR022317 | TNFR_13B
Type: Family
Description: The tumour necrosis factor (TNF) receptor (TNFR) superfamily comprises more than 20 type-I transmembrane proteins. Family members are defined based on similarity in their extracellular domain -a region that contains many cysteine residues arranged in a specific repetitive pattern []. The cysteines allow formation of an extended rod-like structure, responsible for ligand binding []. Upon receptor activation, different intracellular signalling complexes are assembled for different members of the TNFR superfamily, depending on their intracellular domains and sequences []. Activation of TNFRs can therefore induce a range of disparate effects, including cell proliferation, differentiation, survival, or apoptotic cell death, depending upon the receptor involved [, ]. TNFRs are widely distributed and play important roles in many crucial biological processes, such as lymphoid and neuronal development, innate and adaptive immunity, and maintenance of cellular homeostasis []. Drugs that manipulate their signalling have potential roles in the prevention and treatment of many diseases, such as viral infections, coronary heart disease, transplant rejection, and immune disease []. TNF receptor 13B (also known as transmembrane activator and CAML interactor (TACI)) functions as a receptor for B-cell activating factor (BAFF) []. Mutations in TNF receptor 13B cause common variable immunodeficiency (CVID) and IgA deficiency [].
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Publication
25698446 | J:259880
First Author: Woess C
Year: 2015
Journal: Cell Death Differ
Title: Combined loss of the BH3-only proteins Bim and Bmf restores B-cell development and function in TACI-Ig transgenic mice.
Volume: 22
Issue: 9
Pages: 1477-88
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Protein
A5D8Y6
Organism: Mus musculus/domesticus
Length: 249  
Fragment?: false
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Protein
B1ATI4
Organism: Mus musculus/domesticus
Length: 140  
Fragment?: true
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Protein
A5D8Y7
Organism: Mus musculus/domesticus
Length: 249  
Fragment?: false
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Publication
9826575 | -
First Author: Gravestein LA
Year: 1998
Journal: Semin Immunol
Title: Tumor necrosis factor receptor family members in the immune system.
Volume: 10
Issue: 6
Pages: 423-34
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Publication
7917108 | -
First Author: Armitage RJ
Year: 1994
Journal: Curr Opin Immunol
Title: Tumor necrosis factor receptor superfamily members and their ligands.
Volume: 6
Issue: 3
Pages: 407-13
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Publication
15500863 | -
 
First Author: Wu H
Year: 2004
Journal: Adv Protein Chem
Title: Assembly of post-receptor signaling complexes for the tumor necrosis factor receptor superfamily.
Volume: 68
Pages: 225-79
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Publication
11239407 | J:74923
First Author: Locksley RM
Year: 2001
Journal: Cell
Title: The TNF and TNF receptor superfamilies: integrating mammalian biology.
Volume: 104
Issue: 4
Pages: 487-501
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Publication
9826574 | -
First Author: Loenen WA
Year: 1998
Journal: Semin Immunol
Title: CD27 and (TNFR) relatives in the immune system: their role in health and disease.
Volume: 10
Issue: 6
Pages: 417-22
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Publication
8387891 | -
First Author: Banner DW
Year: 1993
Journal: Cell
Title: Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation.
Volume: 73
Issue: 3
Pages: 431-45
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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