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Search results 1 to 100 out of 115 for Tmc1

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Category: Publication
Type Details Score
Publication
First Author: Beurg M
Year: 2021
Journal: J Neurosci
Title: New Tmc1 Deafness Mutations Impact Mechanotransduction in Auditory Hair Cells.
Volume: 41
Issue: 20
Pages: 4378-4391
Publication
First Author: Maeda R
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Tip-link protein protocadherin 15 interacts with transmembrane channel-like proteins TMC1 and TMC2.
Volume: 111
Issue: 35
Pages: 12907-12
Publication    
First Author: Ballesteros A
Year: 2018
Journal: Elife
Title: Structural relationship between the putative hair cell mechanotransduction channel TMC1 and TMEM16 proteins.
Volume: 7
Publication
First Author: Pan B
Year: 2018
Journal: Neuron
Title: TMC1 Forms the Pore of Mechanosensory Transduction Channels in Vertebrate Inner Ear Hair Cells.
Volume: 99
Issue: 4
Pages: 736-753.e6
Publication
First Author: Kurima K
Year: 2015
Journal: Cell Rep
Title: TMC1 and TMC2 Localize at the Site of Mechanotransduction in Mammalian Inner Ear Hair Cell Stereocilia.
Volume: 12
Issue: 10
Pages: 1606-17
Publication
First Author: Akyuz N
Year: 2022
Journal: Sci Adv
Title: Mechanical gating of the auditory transduction channel TMC1 involves the fourth and sixth transmembrane helices.
Volume: 8
Issue: 28
Pages: eabo1126
Publication
First Author: Ballesteros A
Year: 2022
Journal: Sci Adv
Title: Regulation of membrane homeostasis by TMC1 mechanoelectrical transduction channels is essential for hearing.
Volume: 8
Issue: 31
Pages: eabm5550
Publication
First Author: Manji SS
Year: 2012
Journal: Am J Pathol
Title: Identification of three novel hearing loss mouse strains with mutations in the Tmc1 gene.
Volume: 180
Issue: 4
Pages: 1560-9
Publication  
First Author: Marcovich I
Year: 2022
Journal: Biomolecules
Title: Optimized AAV Vectors for TMC1 Gene Therapy in a Humanized Mouse Model of DFNB7/11.
Volume: 12
Issue: 7
Publication
First Author: Goldring AC
Year: 2019
Journal: J Physiol
Title: The contribution of TMC1 to adaptation of mechanoelectrical transduction channels in cochlear outer hair cells.
Volume: 597
Issue: 24
Pages: 5949-5961
Publication
First Author: Li X
Year: 2019
Journal: FASEB J
Title: Localization of TMC1 and LHFPL5 in auditory hair cells in neonatal and adult mice.
Volume: 33
Issue: 6
Pages: 6838-6851
Publication
First Author: Pan B
Year: 2013
Journal: Neuron
Title: TMC1 and TMC2 are components of the mechanotransduction channel in hair cells of the mammalian inner ear.
Volume: 79
Issue: 3
Pages: 504-15
Publication
First Author: Marcotti W
Year: 2006
Journal: J Physiol
Title: Tmc1 is necessary for normal functional maturation and survival of inner and outer hair cells in the mouse cochlea.
Volume: 574
Issue: Pt 3
Pages: 677-98
Publication
First Author: Soler DC
Year: 2019
Journal: Sci Rep
Title: An uncharacterized region within the N-terminus of mouse TMC1 precludes trafficking to plasma membrane in a heterologous cell line.
Volume: 9
Issue: 1
Pages: 15263
Publication    
First Author: Liu S
Year: 2019
Journal: Elife
Title: TMC1 is an essential component of a leak channel that modulates tonotopy and excitability of auditory hair cells in mice.
Volume: 8
Publication
First Author: Giese APJ
Year: 2017
Journal: Nat Commun
Title: CIB2 interacts with TMC1 and TMC2 and is essential for mechanotransduction in auditory hair cells.
Volume: 8
Issue: 1
Pages: 43
Publication
First Author: Corns LF
Year: 2016
Journal: J Neurosci
Title: Tmc1 Point Mutation Affects Ca2+ Sensitivity and Block by Dihydrostreptomycin of the Mechanoelectrical Transducer Current of Mouse Outer Hair Cells.
Volume: 36
Issue: 2
Pages: 336-49
Publication
First Author: Nakanishi H
Year: 2018
Journal: Sci Rep
Title: Tmc2 expression partially restores auditory function in a mouse model of DFNB7/B11 deafness caused by loss of Tmc1 function.
Volume: 8
Issue: 1
Pages: 12125
Publication
First Author: Beurg M
Year: 2015
Journal: J Gen Physiol
Title: The effects of Tmc1 Beethoven mutation on mechanotransducer channel function in cochlear hair cells.
Volume: 146
Issue: 3
Pages: 233-43
Publication
First Author: Noguchi Y
Year: 2006
Journal: Genetics
Title: Multiple quantitative trait loci modify cochlear hair cell degeneration in the Beethoven (Tmc1Bth) mouse model of progressive hearing loss DFNA36.
Volume: 173
Issue: 4
Pages: 2111-9
Publication
First Author: Beurg M
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: A Tmc1 mutation reduces calcium permeability and expression of mechanoelectrical transduction channels in cochlear hair cells.
Volume: 116
Issue: 41
Pages: 20743-20749
Publication
First Author: Vreugde S
Year: 2002
Journal: Nat Genet
Title: Beethoven, a mouse model for dominant, progressive hearing loss DFNA36.
Volume: 30
Issue: 3
Pages: 257-8
Publication    
First Author: Erickson T
Year: 2017
Journal: Elife
Title: Integration of Tmc1/2 into the mechanotransduction complex in zebrafish hair cells is regulated by Transmembrane O-methyltransferase (Tomt).
Volume: 6
Publication
First Author: Beurg M
Year: 2018
Journal: Nat Commun
Title: Variable number of TMC1-dependent mechanotransducer channels underlie tonotopic conductance gradients in the cochlea.
Volume: 9
Issue: 1
Pages: 2185
Publication
First Author: Shibata SB
Year: 2016
Journal: Am J Hum Genet
Title: RNA Interference Prevents Autosomal-Dominant Hearing Loss.
Volume: 98
Issue: 6
Pages: 1101-1113
Publication
First Author: Kurima K
Year: 2002
Journal: Nat Genet
Title: Dominant and recessive deafness caused by mutations of a novel gene, TMC1, required for cochlear hair-cell function.
Volume: 30
Issue: 3
Pages: 277-84
Publication
First Author: Mahendrasingam S
Year: 2019
Journal: Sci Rep
Title: Ultrastructural localization of the likely mechanoelectrical transduction channel protein, transmembrane-like channel 1 (TMC1) during development of cochlear hair cells.
Volume: 9
Issue: 1
Pages: 1274
Publication  
First Author: Yamaguchi S
Year: 2020
Journal: Int J Mol Sci
Title: A Mechanosensitive Channel, Mouse Transmembrane Channel-Like Protein 1 (Mtmc1) Is Translated from a Splice Variant mTmc1ex1 but Not from the Other Variant mTmc1ex2.
Volume: 21
Issue: 18
Publication
First Author: Cunningham CL
Year: 2020
Journal: Neuron
Title: TMIE Defines Pore and Gating Properties of the Mechanotransduction Channel of Mammalian Cochlear Hair Cells.
Volume: 107
Issue: 1
Pages: 126-143.e8
Publication    
First Author: Lee J
Year: 2021
Journal: Elife
Title: Sensory transduction is required for normal development and maturation of cochlear inner hair cell synapses.
Volume: 10
Publication
First Author: Kim KX
Year: 2013
Journal: J Gen Physiol
Title: The role of transmembrane channel-like proteins in the operation of hair cell mechanotransducer channels.
Volume: 142
Issue: 5
Pages: 493-505
Publication  
First Author: Beurg M
Year: 2021
Journal: J Gen Physiol
Title: The speed of the hair cell mechanotransducer channel revealed by fluctuation analysis.
Volume: 153
Issue: 10
Publication
First Author: Gao X
Year: 2018
Journal: Nature
Title: Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents.
Volume: 553
Issue: 7687
Pages: 217-221
Publication
First Author: Askew C
Year: 2015
Journal: Sci Transl Med
Title: Tmc gene therapy restores auditory function in deaf mice.
Volume: 7
Issue: 295
Pages: 295ra108
Publication
First Author: Kurima K
Year: 2003
Journal: Genomics
Title: Characterization of the transmembrane channel-like (TMC) gene family: functional clues from hearing loss and epidermodysplasia verruciformis.
Volume: 82
Issue: 3
Pages: 300-8
Publication
First Author: Wu Z
Year: 2017
Journal: Nat Neurosci
Title: Mechanosensory hair cells express two molecularly distinct mechanotransduction channels.
Volume: 20
Issue: 1
Pages: 24-33
Publication
First Author: Liang X
Year: 2021
Journal: Neuron
Title: CIB2 and CIB3 are auxiliary subunits of the mechanotransduction channel of hair cells.
Volume: 109
Issue: 13
Pages: 2131-2149.e15
Publication
First Author: Beurg M
Year: 2024
Journal: Proc Natl Acad Sci U S A
Title: LHFPL5 is a key element in force transmission from the tip link to the hair cell mechanotransducer channel.
Volume: 121
Issue: 3
Pages: e2318270121
Publication
First Author: Kim KX
Year: 2013
Journal: J Gen Physiol
Title: Developmental changes in the cochlear hair cell mechanotransducer channel and their regulation by transmembrane channel-like proteins.
Volume: 141
Issue: 1
Pages: 141-8
Publication
First Author: Fettiplace R
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: The conductance and organization of the TMC1-containing mechanotransducer channel complex in auditory hair cells.
Volume: 119
Issue: 41
Pages: e2210849119
Publication
First Author: Beurg M
Year: 2014
Journal: J Gen Physiol
Title: Conductance and block of hair-cell mechanotransducer channels in transmembrane channel-like protein mutants.
Volume: 144
Issue: 1
Pages: 55-69
Publication
First Author: Beurg M
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Subunit determination of the conductance of hair-cell mechanotransducer channels.
Volume: 112
Issue: 5
Pages: 1589-94
Publication
First Author: Kawashima Y
Year: 2011
Journal: J Clin Invest
Title: Mechanotransduction in mouse inner ear hair cells requires transmembrane channel-like genes.
Volume: 121
Issue: 12
Pages: 4796-809
Publication
First Author: Asai Y
Year: 2018
Journal: Sci Rep
Title: Transgenic Tmc2 expression preserves inner ear hair cells and vestibular function in mice lacking Tmc1.
Volume: 8
Issue: 1
Pages: 12124
Publication
First Author: Martínez-Cué C
Year: 2005
Journal: Behav Brain Res
Title: Behavioral, cognitive and biochemical responses to different environmental conditions in male Ts65Dn mice, a model of Down syndrome.
Volume: 163
Issue: 2
Pages: 174-85
Publication
First Author: Deol MS
Year: 1958
Journal: Heredity
Title: A new gene for deafness in the mouse.
Volume: 12
Issue: 4
Pages: 463-6
Publication
First Author: Pujol R
Year: 1983
Journal: Hear Res
Title: Early degeneration of sensory and ganglion cells in the inner ear of mice with uncomplicated genetic deafness (dn): preliminary observations.
Volume: 12
Issue: 1
Pages: 57-63
Publication
First Author: Webster DB
Year: 1992
Journal: Exp Neurol
Title: Degeneration followed by partial regeneration of the organ of Corti in deafness (dn/dn) mice.
Volume: 115
Issue: 1
Pages: 27-31
Publication
First Author: Kirsch JP
Year: 1993
Journal: Hear Res
Title: Mice heterozygous for the deafness gene have normal auditory thresholds.
Volume: 67
Issue: 1-2
Pages: 51-4
Publication
First Author: Oleskevich S
Year: 2004
Journal: J Physiol
Title: Presynaptic plasticity at two giant auditory synapses in normal and deaf mice.
Volume: 560
Issue: Pt 3
Pages: 709-19
Publication
First Author: Steel KP
Year: 1984
Journal: Hear Res
Title: Electrically-evoked responses in animals with progressive spiral ganglion degeneration.
Volume: 15
Issue: 1
Pages: 59-67
Publication
First Author: Leao RN
Year: 2004
Journal: J Physiol
Title: Reduced low-voltage activated K+ conductances and enhanced central excitability in a congenitally deaf (dn/dn) mouse.
Volume: 559
Issue: Pt 1
Pages: 25-33
Publication
First Author: Leão RN
Year: 2006
Journal: Eur J Neurosci
Title: Altered sodium currents in auditory neurons of congenitally deaf mice.
Volume: 24
Issue: 4
Pages: 1137-46
Publication
First Author: Leao RN
Year: 2005
Journal: Eur J Neurosci
Title: Hyperpolarization-activated (I) currents in auditory brainstem neurons of normal and congenitally deaf mice.
Volume: 22
Issue: 1
Pages: 147-57
Publication
First Author: Oleskevich S
Year: 2002
Journal: J Physiol
Title: Synaptic transmission in the auditory brainstem of normal and congenitally deaf mice.
Volume: 540
Issue: Pt 2
Pages: 447-55
Publication
First Author: Youssoufian M
Year: 2005
Journal: J Neurophysiol
Title: Development of a robust central auditory synapse in congenital deafness.
Volume: 94
Issue: 5
Pages: 3168-80
Publication
First Author: Keats BJ
Year: 1995
Journal: Mamm Genome
Title: The deafness locus (dn) maps to mouse chromosome 19.
Volume: 6
Issue: 1
Pages: 8-10
Publication
First Author: McKay SM
Year: 2007
Journal: Hear Res
Title: The role of spontaneous activity in development of the endbulb of Held synapse.
Volume: 230
Issue: 1-2
Pages: 53-63
Publication
First Author: Couchman K
Year: 2011
Journal: Hear Res
Title: Lateral superior olive function in congenital deafness.
Volume: 277
Issue: 1-2
Pages: 163-75
Publication
First Author: Steel KP
Year: 1980
Journal: Nature
Title: The nature of inherited deafness in deafness mice.
Volume: 288
Issue: 5787
Pages: 159-61
Publication
First Author: Bock GR
Year: 1982
Journal: Brain Res
Title: Preservation of central auditory function in the deafness mouse.
Volume: 239
Issue: 2
Pages: 608-12
Publication
First Author: Viñas AM
Year: 1998
Journal: Biochim Biophys Acta
Title: The mouse deafness locus (dn) is associated with an inversion on chromosome 19.
Volume: 1407
Issue: 3
Pages: 257-62
Publication
First Author: Scott DA
Year: 1998
Journal: Gene
Title: Identification and mutation analysis of a cochlear-expressed, zinc finger protein gene at the DFNB7/11 and dn hearing-loss loci on human chromosome 9q and mouse chromosome 19.
Volume: 215
Issue: 2
Pages: 461-9
Publication
First Author: Beurg M
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Development and localization of reverse-polarity mechanotransducer channels in cochlear hair cells.
Volume: 113
Issue: 24
Pages: 6767-72
Publication  
First Author: Meng X
Year: 2021
Journal: Sci Adv
Title: Early peripheral activity alters nascent subplate circuits in the auditory cortex.
Volume: 7
Issue: 7
Publication
First Author: Zhao B
Year: 2014
Journal: Neuron
Title: TMIE is an essential component of the mechanotransduction machinery of cochlear hair cells.
Volume: 84
Issue: 5
Pages: 954-67
Publication
First Author: Scott DA
Year: 2000
Journal: Gene
Title: Refining the DFNB7-DFNB11 deafness locus using intragenic polymorphisms in a novel gene, TMEM2.
Volume: 246
Issue: 1-2
Pages: 265-74
Publication
First Author: Krey JF
Year: 2020
Journal: Curr Biol
Title: Mechanotransduction-Dependent Control of Stereocilia Dimensions and Row Identity in Inner Hair Cells.
Volume: 30
Issue: 3
Pages: 442-454.e7
Publication
First Author: Keresztes G
Year: 2003
Journal: BMC Genomics
Title: TMC and EVER genes belong to a larger novel family, the TMC gene family encoding transmembrane proteins.
Volume: 4
Issue: 1
Pages: 24
Publication
First Author: Horner KC
Year: 1985
Journal: J Acoust Soc Am
Title: Distortion product otoacoustic emissions in hearing-impaired mutant mice.
Volume: 78
Issue: 5
Pages: 1603-11
Publication    
First Author: Cunningham CL
Year: 2017
Journal: Elife
Title: The murine catecholamine methyltransferase mTOMT is essential for mechanotransduction by cochlear hair cells.
Volume: 6
Publication
First Author: Lewis MA
Year: 2009
Journal: Nat Genet
Title: An ENU-induced mutation of miR-96 associated with progressive hearing loss in mice.
Volume: 41
Issue: 5
Pages: 614-8
Publication  
First Author: Li J
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: PIEZO2 mediates ultrasonic hearing via cochlear outer hair cells in mice.
Volume: 118
Issue: 28
Publication  
First Author: KOCHER W
Year: 1960
Journal: Z Vererbungsl
Title: [Studies on the genetics and pathology of the development of 8 labyrinth mutants (deaf-waltzer-shaker mutants) in the mouse (Mus musculus)].
Volume: 91
Pages: 114-40
Publication
First Author: Du TT
Year: 2019
Journal: Nat Commun
Title: LMO7 deficiency reveals the significance of the cuticular plate for hearing function.
Volume: 10
Issue: 1
Pages: 1117
Publication
First Author: Keats BJ
Year: 1999
Journal: Genome Res
Title: Genomics and hearing impairment.
Volume: 9
Issue: 1
Pages: 7-16
Publication
First Author: Kaestner KH
Year: 1996
Journal: Mech Dev
Title: Expression of the winged helix genes fkh-4 and fkh-5 defines domains in the central nervous system.
Volume: 55
Issue: 2
Pages: 221-30
Publication
First Author: Karp NA
Year: 2010
Journal: Mamm Genome
Title: Optimising experimental design for high-throughput phenotyping in mice: a case study.
Volume: 21
Issue: 9-10
Pages: 467-76
Publication
First Author: Takayanagi S
Year: 2006
Journal: Blood
Title: Genetic marking of hematopoietic stem and endothelial cells: identification of the Tmtsp gene encoding a novel cell surface protein with the thrombospondin-1 domain.
Volume: 107
Issue: 11
Pages: 4317-25
Publication      
First Author: GSF Mutagenesis Facility
Year: 2003
Journal: MGI Direct Data Submission
Title: Heritable mouse mutants from The National Research Center for Environmental Health (GSF) ENU mutagenesis program
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication
First Author: Kenney-Hunt JP
Year: 2006
Journal: Mamm Genome
Title: Quantitative trait loci for body size components in mice.
Volume: 17
Issue: 6
Pages: 526-37
Publication
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.