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Search results 101 to 125 out of 125 for Rbbp5

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0.019s
Type Details Score
Publication
First Author: Jiang D
Year: 2011
Journal: PLoS Genet
Title: Arabidopsis COMPASS-like complexes mediate histone H3 lysine-4 trimethylation to control floral transition and plant development.
Volume: 7
Issue: 3
Pages: e1001330
Publication
First Author: Ardehali MB
Year: 2011
Journal: EMBO J
Title: Drosophila Set1 is the major histone H3 lysine 4 trimethyltransferase with role in transcription.
Volume: 30
Issue: 14
Pages: 2817-28
Publication
First Author: Mohan M
Year: 2011
Journal: Mol Cell Biol
Title: The COMPASS family of H3K4 methylases in Drosophila.
Volume: 31
Issue: 21
Pages: 4310-8
Protein Domain
Type: Family
Description: This entry includes RBBP5 from animals, RBL from plants and Swd1 from yeasts. Swd1 is a component of the SET1C/COMPASS complex, a complex that methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres [, ].Retinoblastoma-binding protein 5 (RBBP5) is important for development in embryonic stem cells, regulating gene induction and H3 'Lys-4' methylation at key developmental loci []. It is a component of the SET1 histone methyltransferase complex [], and methyltransferase-containing (COMPASS) complexes MLL1, MLL2/3 and MLL4 [, ].Arabidopsis RBL is also a component of a COMPASS-like complex that mediates histone H3 lysine-4 trimethylation to control floral transition and plant development [].
HT Experiment
Series Id: GSE43575
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Su X
Year: 2014
Journal: J Leukoc Biol
Title: Epigenetically modulated LRRC33 acts as a negative physiological regulator for multiple Toll-like receptors.
Volume: 96
Issue: 1
Pages: 17-26
Publication
First Author: Powell WT
Year: 2013
Journal: Hum Mol Genet
Title: A Prader-Willi locus lncRNA cloud modulates diurnal genes and energy expenditure.
Volume: 22
Issue: 21
Pages: 4318-28
Publication
First Author: Lee JH
Year: 2008
Journal: Mol Cell Biol
Title: Wdr82 is a C-terminal domain-binding protein that recruits the Setd1A Histone H3-Lys4 methyltransferase complex to transcription start sites of transcribed human genes.
Volume: 28
Issue: 2
Pages: 609-18
Publication
First Author: Shinsky SA
Year: 2015
Journal: J Biol Chem
Title: Biochemical reconstitution and phylogenetic comparison of human SET1 family core complexes involved in histone methylation.
Volume: 290
Issue: 10
Pages: 6361-75
Protein Domain
Type: Domain
Description: This entry represents the RNA recognition motif (RRM) of Setd1A (also known as Set1A), a ubiquitously expressed vertebrates histone methyltransferase that exhibits high homology to yeast Set1. Set1A is localized to euchromatic nuclear speckles and associates with a complex containing six human homologs of the yeast Set1/COMPASS complex, including CXXC finger protein 1 (CFP1; homologous to yeast Spp1), Rbbp5 (homologous to yeast Swd1), Ash2 (homologous to yeast Bre2), Wdr5 (homologous to yeast Swd3), and Wdr82 (homologous to yeast Swd2) []. Set1A contains an N-terminal RNA recognition motif (RRM), an N-SET domain, and a C-terminal catalytic SET domain followed by a post-SET domain. In contrast to Set1B, Set1A additionally contains an HCF-1 binding motif that interacts with HCF-1 in vivo.
Protein Domain
Type: Domain
Description: This entry represents the RNA recognition motif (RRM) of Setd1B (also known as Set1B), a ubiquitously expressed vertebrates histone methyltransferase that exhibits high homology to yeast Set1. Set1B is localised to euchromatic nuclear speckles and associates with a complex containing six human homologues of the yeast Set1/COMPASS complex, including CXXC finger protein 1 (CFP1; homologous to yeast Spp1), Rbbp5 (homologous to yeast Swd1), Ash2 (homologous to yeast Bre2), Wdr5 (homologous to yeast Swd3), and Wdr82 (homologous to yeast Swd2). Set1B complex is a histone methyltransferase that produces trimethylated histone H3 at Lys4 [, ]. Set1B contains an N-terminal RNA recognition motif (RRM), an N-SET domain, and a C-terminal catalytic SET domain followed by a post-SET domain.
Protein
Organism: Mus musculus/domesticus
Length: 538  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 149  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 537  
Fragment?: false
Publication
First Author: Krogan NJ
Year: 2002
Journal: J Biol Chem
Title: COMPASS, a histone H3 (Lysine 4) methyltransferase required for telomeric silencing of gene expression.
Volume: 277
Issue: 13
Pages: 10753-5
Publication
First Author: Roguev A
Year: 2001
Journal: EMBO J
Title: The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4.
Volume: 20
Issue: 24
Pages: 7137-48
Publication
First Author: Patel A
Year: 2009
Journal: J Biol Chem
Title: On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex.
Volume: 284
Issue: 36
Pages: 24242-56
Protein
Organism: Mus musculus/domesticus
Length: 410  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 107  
Fragment?: true
Publication
First Author: Lee JH
Year: 2007
Journal: J Biol Chem
Title: Identification and characterization of the human Set1B histone H3-Lys4 methyltransferase complex.
Volume: 282
Issue: 18
Pages: 13419-28
Protein
Organism: Mus musculus/domesticus
Length: 737  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 247  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 196  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1716  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1985  
Fragment?: false