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Search results 101 to 121 out of 121 for Sgta

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0.017s
Type Details Score
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Interaction Experiment
Description: Binding of SGTA to Rpn13 selectively modulates protein quality control.
Publication
First Author: Leznicki P
Year: 2015
Journal: J Cell Sci
Title: Binding of SGTA to Rpn13 selectively modulates protein quality control.
Volume: 128
Issue: 17
Pages: 3187-96
GO Term
Publication
First Author: Kuwabara N
Year: 2015
Journal: J Biol Chem
Title: Structure of a BAG6 (Bcl-2-associated athanogene 6)-Ubl4a (ubiquitin-like protein 4a) complex reveals a novel binding interface that functions in tail-anchored protein biogenesis.
Volume: 290
Issue: 15
Pages: 9387-98
Protein Domain
Type: Domain
Description: This is the C-terminal domain of Ubiquitin-like protein 4A, an orthologue of yeast Get5. In budding yeasts, Get proteins directly mediate the insertion of newly synthesized TA proteins into endoplasmic reticulum membranes. Similarly, mammalian BAG6, Ubl4a, and SGTA make up a trimeric complex that binds TA proteins post-translationally and then loads them onto the cytosolic ATPase TRC40, which in turn targets them to the endoplasmic reticulum. Structural studies show that this C-terminal TUGS domain of Ubl4a is essential for BAG6 tethering. Given that BAG6 mediates oligomeric complex formation of Ubl4a, TRC35, and TRC40 (mammalian counterparts of Get5, Get4, and Get3, respectively), the C-terminal TUGS domain might be crucial for supporting BAG6-mediated Ubl4a-TRC35 complexformation in humans as an alternative to the direct Get5-Get4 interaction in yeast [, ].
Publication
First Author: Mock JY
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Bag6 complex contains a minimal tail-anchor-targeting module and a mock BAG domain.
Volume: 112
Issue: 1
Pages: 106-11
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 188  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 157  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 157  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 157  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 172  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 152  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 157  
Fragment?: false
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory