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Search results 1 to 100 out of 811 for Pik3r1

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Type Details Score
Gene
5295 | PIK3R1
Type: gene
Organism: human
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Gene
557176 | pik3r1
Type: gene
Organism: zebrafish
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Gene
698996 | PIK3R1
Type: gene
Organism: macaque, rhesus
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Gene
100486835 | pik3r1
Type: gene
Organism: frog, western clawed
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Gene
25513 | Pik3r1
Type: gene
Organism: rat
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Gene
461836 | PIK3R1
Type: gene
Organism: chimpanzee
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Gene
487235 | PIK3R1
Type: gene
Organism: dog, domestic
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Gene
282307 | PIK3R1
Type: gene
Organism: cattle
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Gene
427171 | PIK3R1
Type: gene
Organism: chicken
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Protein Coding Gene
MGI:97583 | Pik3r1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
36943234 | J:340835
 
First Author: Nguyen T
Year: 2023
Journal: J Exp Med
Title: Human PIK3R1 mutations disrupt lymphocyte differentiation to cause activated PI3Kδ syndrome 2.
Volume: 220
Issue: 6
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Publication
28292967 | J:246241
First Author: Kuo T
Year: 2017
Journal: Diabetes
Title: Pik3r1 Is Required for Glucocorticoid-Induced Perilipin 1 Phosphorylation in Lipid Droplet for Adipocyte Lipolysis.
Volume: 66
Issue: 6
Pages: 1601-1610
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Publication
22698915 | J:208529
First Author: McCurdy CE
Year: 2012
Journal: Diabetes
Title: Attenuated Pik3r1 expression prevents insulin resistance and adipose tissue macrophage accumulation in diet-induced obese mice.
Volume: 61
Issue: 10
Pages: 2495-505
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Publication
33567340 | J:305235
   
First Author: Chen TC
Year: 2021
Journal: J Biol Chem
Title: The role of striated muscle Pik3r1 in glucose and protein metabolism following chronic glucocorticoid exposure.
Pages: 100395
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Publication
27157990 | J:233829
First Author: Cohran V
Year: 2016
Journal: Am J Pathol
Title: Epithelial PIK3R1 (p85) and TP53 Regulate Survivin Expression during Adaptation to Ileocecal Resection.
Volume: 186
Issue: 7
Pages: 1837-46
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GXD Expression
GXD Expression
   
Probe: MGI:6180639
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191081
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Pik3r1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6180639
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191081
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Pik3r1
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6180639
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191081
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Pik3r1
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6180639
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191081
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Pik3r1
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6180639
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191081
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Pik3r1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6180639
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191081
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Pik3r1
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6180639
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191081
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Pik3r1
Detected: true
Specimen Num: 7
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Protein
Q99LY6
Organism: Mus musculus/domesticus
Length: 25  
Fragment?: true
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Publication
14673165 | J:87598
First Author: Chen D
Year: 2004
Journal: Mol Cell Biol
Title: p50alpha/p55alpha phosphoinositide 3-kinase knockout mice exhibit enhanced insulin sensitivity.
Volume: 24
Issue: 1
Pages: 320-9
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Publication
28630349 | J:244500
First Author: Thorpe LM
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: PI3K-p110α mediates the oncogenic activity induced by loss of the novel tumor suppressor PI3K-p85α.
Volume: 114
Issue: 27
Pages: 7095-7100
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Publication
20530665 | J:161603
First Author: Taniguchi CM
Year: 2010
Journal: Cancer Res
Title: The phosphoinositide 3-kinase regulatory subunit p85alpha can exert tumor suppressor properties through negative regulation of growth factor signaling.
Volume: 70
Issue: 13
Pages: 5305-15
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Publication
11781359 | J:73714
First Author: Mauvais-Jarvis F
Year: 2002
Journal: J Clin Invest
Title: Reduced expression of the murine p85alpha subunit of phosphoinositide 3-kinase improves insulin signaling and ameliorates diabetes.
Volume: 109
Issue: 1
Pages: 141-9
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Publication
14976048 | J:90971
First Author: Kharas MG
Year: 2004
Journal: Blood
Title: Phosphoinositide 3-kinase signaling is essential for ABL oncogene-mediated transformation of B-lineage cells.
Volume: 103
Issue: 11
Pages: 4268-75
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Publication
16679292 | J:129647
First Author: Taniguchi CM
Year: 2006
Journal: Cell Metab
Title: Divergent regulation of hepatic glucose and lipid metabolism by phosphoinositide 3-kinase via Akt and PKClambda/zeta.
Volume: 3
Issue: 5
Pages: 343-53
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Publication
21109194 | J:168115
First Author: Kaneko K
Year: 2010
Journal: Cell Metab
Title: Class IA phosphatidylinositol 3-kinase in pancreatic β cells controls insulin secretion by multiple mechanisms.
Volume: 12
Issue: 6
Pages: 619-32
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Publication
11062485 | J:65523
First Author: Fruman DA
Year: 2000
Journal: Nat Genet
Title: Hypoglycaemia, liver necrosis and perinatal death in mice lacking all isoforms of phosphoinositide 3-kinase p85 alpha.
Volume: 26
Issue: 3
Pages: 379-82
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Publication
21730346 | J:181401
First Author: Ivanovic I
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Phosphoinositide 3-kinase signaling in retinal rod photoreceptors.
Volume: 52
Issue: 9
Pages: 6355-62
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Publication
26974159 | J:234657
First Author: Winnay JN
Year: 2016
Journal: J Clin Invest
Title: PI3-kinase mutation linked to insulin and growth factor resistance in vivo.
Volume: 126
Issue: 4
Pages: 1401-12
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Publication
11784871 | J:125968
First Author: Ueki K
Year: 2002
Journal: Mol Cell Biol
Title: Molecular balance between the regulatory and catalytic subunits of phosphoinositide 3-kinase regulates cell signaling and survival.
Volume: 22
Issue: 3
Pages: 965-77
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Publication
19705443 | J:152699
First Author: Mouta-Bellum C
Year: 2009
Journal: Dev Dyn
Title: Organ-specific lymphangiectasia, arrested lymphatic sprouting, and maturation defects resulting from gene-targeting of the PI3K regulatory isoforms p85alpha, p55alpha, and p50alpha.
Volume: 238
Issue: 10
Pages: 2670-9
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Publication
29724723 | J:263499
First Author: Solheim MH
Year: 2018
Journal: Diabetes
Title: Mice Carrying a Dominant-Negative Human PI3K Mutation Are Protected From Obesity and Hepatic Steatosis but Not Diabetes.
Volume: 67
Issue: 7
Pages: 1297-1309
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Publication
18704194 | J:140852
First Author: Kharas MG
Year: 2008
Journal: J Clin Invest
Title: Ablation of PI3K blocks BCR-ABL leukemogenesis in mice, and a dual PI3K/mTOR inhibitor prevents expansion of human BCR-ABL+ leukemia cells.
Volume: 118
Issue: 9
Pages: 3038-50
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Publication
27708159 | J:236520
First Author: Zhang Z
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Insulin resistance and diabetes caused by genetic or diet-induced KBTBD2 deficiency in mice.
Volume: 113
Issue: 42
Pages: E6418-E6426
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Protein Coding Gene
MGP_CAROLIEiJ_G0018852 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0020897 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0020848 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0020823 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0020848 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0020637 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_97583 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0021282 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0020156 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0020599 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0020723 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0020705 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0020797 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0020733 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0021321 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0019909 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0020214 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0015924 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0019731 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
1849460 | J:17845
First Author: Escobedo JA
Year: 1991
Journal: Cell
Title: cDNA cloning of a novel 85 kd protein that has SH2 domains and regulates binding of PI3-kinase to the PDGF beta-receptor.
Volume: 65
Issue: 1
Pages: 75-82
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Publication
8921377 | J:35800
First Author: Fruman DA
Year: 1996
Journal: Genomics
Title: Structural organization and alternative splicing of the murine phosphoinositide 3-kinase p85 alpha gene.
Volume: 37
Issue: 1
Pages: 113-21
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Publication
17475862 | J:146117
First Author: Verkoczy L
Year: 2007
Journal: J Immunol
Title: Basal B cell receptor-directed phosphatidylinositol 3-kinase signaling turns off RAGs and promotes B cell-positive selection.
Volume: 178
Issue: 10
Pages: 6332-41
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Publication
- | J:254890
     
First Author: SoRelle J
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for anubis
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Publication
12623844 | J:106371
First Author: Huddleston H
Year: 2003
Journal: Blood
Title: Functional p85alpha gene is required for normal murine fetal erythropoiesis.
Volume: 102
Issue: 1
Pages: 142-5
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Publication
16166093 | J:102897
First Author: Barbour LA
Year: 2005
Journal: J Biol Chem
Title: Increased P85alpha is a potent negative regulator of skeletal muscle insulin signaling and induces in vivo insulin resistance associated with growth hormone excess.
Volume: 280
Issue: 45
Pages: 37489-94
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Publication
10681597 | J:60675
First Author: Lu-Kuo JM
Year: 2000
Journal: J Biol Chem
Title: Impaired kit- but not FcepsilonRI-initiated mast cell activation in the absence of phosphoinositide 3-kinase p85alpha gene products.
Volume: 275
Issue: 8
Pages: 6022-9
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Publication
26565021 | J:230936
First Author: Goretsky T
Year: 2016
Journal: J Biol Chem
Title: A Cytosolic Multiprotein Complex Containing p85α Is Required for β-Catenin Activation in Colitis and Colitis-associated Cancer.
Volume: 291
Issue: 8
Pages: 4166-77
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Publication
19541766 | J:157340
First Author: Acosta-Martínez M
Year: 2009
Journal: Endocrinology
Title: Male-biased effects of gonadotropin-releasing hormone neuron-specific deletion of the phosphoinositide 3-kinase regulatory subunit p85alpha on the reproductive axis.
Volume: 150
Issue: 9
Pages: 4203-12
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Publication
- | J:254892
     
First Author: Zhong X
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Rocket
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Publication
18809581 | J:142822
First Author: Munugalavadla V
Year: 2008
Journal: Mol Cell Biol
Title: The p85alpha subunit of class IA phosphatidylinositol 3-kinase regulates the expression of multiple genes involved in osteoclast maturation and migration.
Volume: 28
Issue: 23
Pages: 7182-98
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Publication
15769893 | J:107453
First Author: Munugalavadla V
Year: 2005
Journal: Blood
Title: p85alpha subunit of class IA PI-3 kinase is crucial for macrophage growth and migration.
Volume: 106
Issue: 1
Pages: 103-9
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Publication
17324588 | J:123234
First Author: Zhu W
Year: 2007
Journal: Mol Cell Neurosci
Title: Phosphoinositide-3-kinase and mitogen activated protein kinase signaling pathways mediate acute NGF sensitization of TRPV1.
Volume: 34
Issue: 4
Pages: 689-700
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Publication
11850627 | J:74995
First Author: Fukao T
Year: 2002
Journal: Nat Immunol
Title: Selective loss of gastrointestinal mast cells and impaired immunity in PI3K-deficient mice.
Volume: 3
Issue: 3
Pages: 295-304
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Publication
15331535 | J:92073
First Author: Terauchi Y
Year: 2004
Journal: Diabetes
Title: Increased serum leptin protects from adiposity despite the increased glucose uptake in white adipose tissue in mice lacking p85alpha phosphoinositide 3-kinase.
Volume: 53
Issue: 9
Pages: 2261-70
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Publication
19176357 | J:148128
First Author: Aoki K
Year: 2009
Journal: Am J Physiol Endocrinol Metab
Title: Role of the liver in glucose homeostasis in PI 3-kinase p85alpha-deficient mice.
Volume: 296
Issue: 4
Pages: E842-53
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Publication
28733636 | J:253698
First Author: Hayashi S
Year: 2017
Journal: Sci Rep
Title: PI3K p85α Subunit-deficient Macrophages Protect Mice from Acute Colitis due to the Enhancement of IL-10 Production.
Volume: 7
Issue: 1
Pages: 6187
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Publication
11756327 | J:107165
First Author: Eto K
Year: 2002
Journal: Diabetes
Title: Phosphatidylinositol 3-kinase suppresses glucose-stimulated insulin secretion by affecting post-cytosolic [Ca(2+)] elevation signals.
Volume: 51
Issue: 1
Pages: 87-97
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Publication
22297723 | J:190782
First Author: Ma P
Year: 2012
Journal: Leukemia
Title: Role of intracellular tyrosines in activating KIT-induced myeloproliferative disease.
Volume: 26
Issue: 7
Pages: 1499-1506
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Publication
18303010 | J:133522
First Author: Doi T
Year: 2008
Journal: Int Immunol
Title: PI3K is a negative regulator of IgE production.
Volume: 20
Issue: 4
Pages: 499-508
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Publication
12649157 | J:110764
First Author: Watanabe N
Year: 2003
Journal: Blood
Title: Functional phenotype of phosphoinositide 3-kinase p85alpha-null platelets characterized by an impaired response to GP VI stimulation.
Volume: 102
Issue: 2
Pages: 541-8
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Publication
22238586 | J:184151
First Author: Krishnan S
Year: 2012
Journal: PLoS One
Title: Class I(A) PI3Kinase regulatory subunit, p85α, mediates mast cell development through regulation of growth and survival related genes.
Volume: 7
Issue: 1
Pages: e28979
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Publication
38909849 | J:350428
First Author: Zhu K
Year: 2024
Journal: Biochim Biophys Acta Mol Basis Dis
Title: p85α deficiency alleviates ischemia-reperfusion injury by promoting cardiomyocyte survival.
Volume: 1870
Issue: 7
Pages: 167318
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Publication
16670329 | J:131759
First Author: Yu Y
Year: 2006
Journal: J Immunol
Title: TLR5-mediated phosphoinositide 3-kinase activation negatively regulates flagellin-induced proinflammatory gene expression.
Volume: 176
Issue: 10
Pages: 6194-201
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Publication
21324896 | J:171139
First Author: Wu X
Year: 2011
Journal: J Biol Chem
Title: p85alpha regulates osteoblast differentiation by cross-talking with the MAPK pathway.
Volume: 286
Issue: 15
Pages: 13512-21
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Publication
12429725 | J:124450
First Author: Yasui K
Year: 2002
Journal: J Leukoc Biol
Title: Granulocyte macrophage-colony stimulating factor delays neutrophil apoptosis and primes its function through Ia-type phosphoinositide 3-kinase.
Volume: 72
Issue: 5
Pages: 1020-6
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Publication
28632845 | J:257051
First Author: Solheim MH
Year: 2017
Journal: Invest Ophthalmol Vis Sci
Title: Iris Malformation and Anterior Segment Dysgenesis in Mice and Humans With a Mutation in PI 3-Kinase.
Volume: 58
Issue: 7
Pages: 3100-3106
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Publication
- | J:272853
     
First Author: Zhong X
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for astro_boy.
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Publication
16043515 | J:114734
First Author: Luo J
Year: 2005
Journal: J Cell Biol
Title: The p85 regulatory subunit of phosphoinositide 3-kinase down-regulates IRS-1 signaling via the formation of a sequestration complex.
Volume: 170
Issue: 3
Pages: 455-64
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Publication
11038173 | J:292595
First Author: Jiménez C
Year: 2000
Journal: J Cell Biol
Title: Role of the PI3K regulatory subunit in the control of actin organization and cell migration.
Volume: 151
Issue: 2
Pages: 249-62
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Publication
7504175 | J:327402
First Author: Sun XJ
Year: 1993
Journal: Mol Cell Biol
Title: Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1.
Volume: 13
Issue: 12
Pages: 7418-28
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Publication
20598684 | J:200509
First Author: Dubielecka PM
Year: 2010
Journal: FEBS Lett
Title: Abi1/Hssh3bp1 pY213 links Abl kinase signaling to p85 regulatory subunit of PI-3 kinase in regulation of macropinocytosis in LNCaP cells.
Volume: 584
Issue: 15
Pages: 3279-86
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Publication
10783143 | J:61807
First Author: Borlado LR
Year: 2000
Journal: FASEB J
Title: Increased phosphoinositide 3-kinase activity induces a lymphoproliferative disorder and contributes to tumor generation in vivo.
Volume: 14
Issue: 7
Pages: 895-903
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Publication
8054357 | J:19783
First Author: Fry MJ
Year: 1994
Journal: Biochim Biophys Acta
Title: Structure, regulation and function of phosphoinositide 3-kinases.
Volume: 1226
Issue: 3
Pages: 237-68
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Publication
7698770 | J:21917
First Author: Hoyle J
Year: 1994
Journal: Genomics
Title: The gene that encodes the phosphatidylinositol-3 kinase regulatory subunit (p85 alpha) maps to chromosome 13 in the mouse.
Volume: 24
Issue: 2
Pages: 400-2
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Publication
8706703 | J:34363
First Author: Ricort JM
Year: 1996
Journal: Eur J Biochem
Title: Different effects of insulin and platelet-derived growth factor on phosphatidylinositol 3-kinase at the subcellular level in 3T3-L1 adipocytes. A possible explanation for their specific effects on glucose transport.
Volume: 239
Issue: 1
Pages: 17-22
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Publication
8754810 | J:34390
First Author: Klippel A
Year: 1996
Journal: Mol Cell Biol
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