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Search results 101 to 200 out of 216 for Numa1

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Type Details Score
GXD Expression
GXD Expression
Probe: MGI:6864131
Assay Type: Immunohistochemistry
Annotation Date: 2022-02-03
Strength: Present
Sex: Female
Emaps: EMAPS:3575528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6864139
Age: postnatal adult
Image: 3e/f
Note: Expression much wider compared to that of RIC8 (Ric8a).
Specimen Label: 3e/f
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:6864131
Assay Type: Immunohistochemistry
Annotation Date: 2022-02-03
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6864139
Age: postnatal adult
Image: 5B/C
Note: When chromosomes segregate, expression translocated to spindle midzone.
Specimen Label: 5B/C
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:6864131
Assay Type: Immunohistochemistry
Annotation Date: 2022-02-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Pattern: Regionally restricted
Stage: TS02
Assay Id: MGI:6864139
Age: embryonic day 1.0
Image: 7K/L
Note: Expression in nucleus of blastomeres. No overlap with RIC8 (Ric8a) in cortex region.
Specimen Label: 7K/L
Detected: true
Specimen Num: 8
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Publication
26766442 | J:239972
First Author: Chiu CWN
Year: 2016
Journal: Dev Cell
Title: SAPCD2 Controls Spindle Orientation and Asymmetric Divisions by Negatively Regulating the Gαi-LGN-NuMA Ternary Complex.
Volume: 36
Issue: 1
Pages: 50-62
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Publication
31577227 | J:290859
   
First Author: Morrow A
Year: 2019
Journal: Elife
Title: Regulated spindle orientation buffers tissue growth in the epidermis.
Volume: 8
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Publication
28469279 | J:275317
First Author: Magescas J
Year: 2017
Journal: Sci Rep
Title: Spindle pole cohesion requires glycosylation-mediated localization of NuMA.
Volume: 7
Issue: 1
Pages: 1474
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Publication
25936915 | J:306588
First Author: Zhao B
Year: 2015
Journal: Cell Stem Cell
Title: Filia Is an ESC-Specific Regulator of DNA Damage Response and Safeguards Genomic Stability.
Volume: 16
Issue: 6
Pages: 684-98
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Publication
18408763 | J:138508
First Author: Sukhai MA
Year: 2008
Journal: Oncogene
Title: Evidence of functional interaction between NuMA-RARalpha and RXRalpha in an in vivo model of acute promyelocytic leukemia.
Volume: 27
Issue: 34
Pages: 4666-77
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Publication
18331714 | J:204810
First Author: Wang X
Year: 2008
Journal: Dev Cell
Title: sSgo1, a major splice variant of Sgo1, functions in centriole cohesion where it is regulated by Plk1.
Volume: 14
Issue: 3
Pages: 331-41
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Publication
25139855 | J:214812
First Author: Chaffee BR
Year: 2014
Journal: Development
Title: Nuclear removal during terminal lens fiber cell differentiation requires CDK1 activity: appropriating mitosis-related nuclear disassembly.
Volume: 141
Issue: 17
Pages: 3388-98
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Publication
21098114 | J:166997
First Author: Poulson ND
Year: 2010
Journal: J Cell Biol
Title: Robust control of mitotic spindle orientation in the developing epidermis.
Volume: 191
Issue: 5
Pages: 915-22
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Publication
34432485 | J:324129
First Author: Moreci RS
Year: 2021
Journal: Mol Biol Cell
Title: KIF18B is a cell type-specific regulator of spindle orientation in the epidermis.
Volume: 32
Issue: 21
Pages: ar29
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Publication
21385765 | J:171504
First Author: El-Hashash AH
Year: 2011
Journal: Development
Title: Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium.
Volume: 138
Issue: 7
Pages: 1395-407
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Publication
26062014 | J:237701
First Author: Saare M
Year: 2015
Journal: PLoS One
Title: Expression Pattern and Localization Dynamics of Guanine Nucleotide Exchange Factor RIC8 during Mouse Oogenesis.
Volume: 10
Issue: 6
Pages: e0129131
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Publication
28716713 | J:249114
First Author: Cavalheiro GR
Year: 2017
Journal: Dev Biol
Title: N-myc regulates growth and fiber cell differentiation in lens development.
Volume: 429
Issue: 1
Pages: 105-117
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Publication
21246661 | J:167828
First Author: El-Hashash AH
Year: 2011
Journal: Dev Dyn
Title: Cell polarity and spindle orientation in the distal epithelium of embryonic lung.
Volume: 240
Issue: 2
Pages: 441-5
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Publication
26765568 | J:229900
   
First Author: Seldin L
Year: 2016
Journal: Elife
Title: NuMA-microtubule interactions are critical for spindle orientation and the morphogenesis of diverse epidermal structures.
Volume: 5
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Publication
21429982 | J:171221
First Author: Croyle MJ
Year: 2011
Journal: Development
Title: Role of epidermal primary cilia in the homeostasis of skin and hair follicles.
Volume: 138
Issue: 9
Pages: 1675-85
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Publication
37143315 | J:338401
     
First Author: Nutter CA
Year: 2023
Journal: Brain
Title: Choroid plexus mis-splicing and altered cerebrospinal fluid composition in myotonic dystrophy type 1.
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Publication
11092755 | J:106641
First Author: Hilditch-Maguire P
Year: 2000
Journal: Hum Mol Genet
Title: Huntingtin: an iron-regulated protein essential for normal nuclear and perinuclear organelles.
Volume: 9
Issue: 19
Pages: 2789-97
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Publication
24749073 | J:309675
First Author: Elias S
Year: 2014
Journal: Stem Cell Reports
Title: Huntingtin regulates mammary stem cell division and differentiation.
Volume: 2
Issue: 4
Pages: 491-506
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Publication
36973253 | J:334512
First Author: He S
Year: 2023
Journal: Nat Commun
Title: Distinct dynein complexes defined by DYNLRB1 and DYNLRB2 regulate mitotic and male meiotic spindle bipolarity.
Volume: 14
Issue: 1
Pages: 1715
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Publication
19332887 | J:147346
First Author: Lake BB
Year: 2009
Journal: J Cell Biol
Title: Strabismus regulates asymmetric cell divisions and cell fate determination in the mouse brain.
Volume: 185
Issue: 1
Pages: 59-66
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Publication
33013468 | J:297684
 
First Author: Hooper JE
Year: 2020
Journal: Front Physiol
Title: An Alternative Splicing Program for Mouse Craniofacial Development.
Volume: 11
Pages: 1099
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Publication
33899739 | J:308321
   
First Author: Lau EO
Year: 2021
Journal: Elife
Title: DIAPH3 deficiency links microtubules to mitotic errors, defective neurogenesis, and brain dysfunction.
Volume: 10
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Publication
26876178 | J:315122
First Author: Passer D
Year: 2016
Journal: Cell Rep
Title: Atypical Protein Kinase C-Dependent Polarized Cell Division Is Required for Myocardial Trabeculation.
Volume: 14
Issue: 7
Pages: 1662-1672
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Publication
30923192 | J:277726
 
First Author: Lecland N
Year: 2019
Journal: Life Sci Alliance
Title: Epidermal development requires ninein for spindle orientation and cortical microtubule organization.
Volume: 2
Issue: 2
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Publication
36685938 | J:332918
 
First Author: Cai S
Year: 2022
Journal: Front Genet
Title: Transcriptomic analysis of the upper lip and primary palate development in mice.
Volume: 13
Pages: 1039850
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Publication
32492419 | J:306456
First Author: Farini D
Year: 2020
Journal: Cell Rep
Title: A Dynamic Splicing Program Ensures Proper Synaptic Connections in the Developing Cerebellum.
Volume: 31
Issue: 9
Pages: 107703
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Publication
33798452 | J:314103
First Author: Ulmke PA
Year: 2021
Journal: Stem Cell Reports
Title: Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex.
Volume: 16
Issue: 4
Pages: 968-984
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Publication
11180952 | J:67747
First Author: Thut CJ
Year: 2001
Journal: Dev Biol
Title: A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens.
Volume: 231
Issue: 1
Pages: 63-76
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein Domain
IPR021187 | Band_41_protein_chordates
Type: Family
Description: Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating physical properties of the membrane, such as mechanical stability and de-formability, by stabilising spectrin-actin interactions [, , ]. It is required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase [].The protein has been shown to associate with the nuclear mitotic apparatus, the contractile apparatus and tight junctions. Defects in this protein can cause elliptocytosis type 1 and hereditary pyropoikilocytosis.Note: Band 4.1 and Band 7 () proteins refer to human erythrocyte membrane proteins separated by SDS polyacrylamide gels and stained with coomassie blue [].
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Publication
11017195 | -
First Author: Han BG
Year: 2000
Journal: Nat Struct Biol
Title: Protein 4.1R core domain structure and insights into regulation of cytoskeletal organization.
Volume: 7
Issue: 10
Pages: 871-5
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Publication
1647028 | -
First Author: Subrahmanyam G
Year: 1991
Journal: Proc Natl Acad Sci U S A
Title: Phosphorylation of protein 4.1 on tyrosine-418 modulates its function in vitro.
Volume: 88
Issue: 12
Pages: 5222-6
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Publication
23870127 | -
First Author: Kiyomitsu T
Year: 2013
Journal: Cell
Title: Cortical dynein and asymmetric membrane elongation coordinately position the spindle in anaphase.
Volume: 154
Issue: 2
Pages: 391-402
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Protein
Q9EPM7
Organism: Mus musculus/domesticus
Length: 159  
Fragment?: true
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Protein
A0A1W2P8C0
Organism: Mus musculus/domesticus
Length: 204  
Fragment?: true
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Protein
Q9EPM8
Organism: Mus musculus/domesticus
Length: 204  
Fragment?: true
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Publication
9598318 | -
First Author: Parra M
Year: 1998
Journal: Genomics
Title: Cloning and characterization of 4.1G (EPB41L2), a new member of the skeletal protein 4.1 (EPB41) gene family.
Volume: 49
Issue: 2
Pages: 298-306
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Protein Domain
IPR030546 | E41L2
Type: Family
Description: This entry represents band 4.1-like protein 2 []. It shares protein sequence similarity with Band 4.1 protein. Its function is not clear.Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating physical properties of the membrane, such as mechanical stability and de-formability, by stabilising spectrin-actin interactions [, , ]. It is required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase [].The protein has been shown to associate with the nuclear mitotic apparatus, the contractile apparatus and tight junctions. Defects in this protein can cause elliptocytosis type 1 and hereditary pyropoikilocytosis.Note: Band 4.1 and Band 7 () proteins refer to human erythrocyte membrane proteins separated by SDS polyacrylamide gels and stained with coomassie blue [].
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Publication
11003675 | -
First Author: Hung LY
Year: 2000
Journal: Mol Cell Biol
Title: Protein 4.1 R-135 interacts with a novel centrosomal protein (CPAP) which is associated with the gamma-tubulin complex.
Volume: 20
Issue: 20
Pages: 7813-25
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Protein
A0A1W2P6H2
Organism: Mus musculus/domesticus
Length: 131  
Fragment?: true
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Protein
B6ZHC3
Organism: Mus musculus/domesticus
Length: 184  
Fragment?: true
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Protein
Q8BSR4
Organism: Mus musculus/domesticus
Length: 114  
Fragment?: true
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Protein
Q7TPN6
Organism: Mus musculus/domesticus
Length: 297  
Fragment?: false
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Protein
B6ZHC2
Organism: Mus musculus/domesticus
Length: 317  
Fragment?: true
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Publication
4326772 | -
First Author: Fairbanks G
Year: 1971
Journal: Biochemistry
Title: Electrophoretic analysis of the major polypeptides of the human erythrocyte membrane.
Volume: 10
Issue: 13
Pages: 2606-17
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Protein
Q3V048
Organism: Mus musculus/domesticus
Length: 172  
Fragment?: false
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Protein
F7BUB8
Organism: Mus musculus/domesticus
Length: 250  
Fragment?: true
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Protein
F6S4K9
Organism: Mus musculus/domesticus
Length: 375  
Fragment?: true
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Protein
A0A1W2P7I2
Organism: Mus musculus/domesticus
Length: 201  
Fragment?: false
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Protein
A0A1D5RLV1
Organism: Mus musculus/domesticus
Length: 476  
Fragment?: true
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Protein
A2A842
Organism: Mus musculus/domesticus
Length: 769  
Fragment?: false
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Protein
Q811C0
Organism: Mus musculus/domesticus
Length: 474  
Fragment?: true
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Protein
Q3UH12
Organism: Mus musculus/domesticus
Length: 476  
Fragment?: true
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Protein
P48193
Organism: Mus musculus/domesticus
Length: 858  
Fragment?: false
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Protein
O70318
Organism: Mus musculus/domesticus
Length: 988  
Fragment?: false
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Protein
Q80UE4
Organism: Mus musculus/domesticus
Length: 794  
Fragment?: false
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Protein
Q811B2
Organism: Mus musculus/domesticus
Length: 689  
Fragment?: false
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Protein
B6ZHD0
Organism: Mus musculus/domesticus
Length: 988  
Fragment?: false
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Protein
A2AD32
Organism: Mus musculus/domesticus
Length: 767  
Fragment?: false
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Protein
B6ZHC5
Organism: Mus musculus/domesticus
Length: 794  
Fragment?: false
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