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Search results 1 to 100 out of 382 for Cacna1a

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Type Details Score
Publication
17146767 | J:117062
First Author: Todorov B
Year: 2006
Journal: Genesis
Title: Conditional inactivation of the Cacna1a gene in transgenic mice.
Volume: 44
Issue: 12
Pages: 589-94
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22952933 | J:191648
First Author: Li W
Year: 2012
Journal: PLoS One
Title: New ataxic tottering-6j mouse allele containing a Cacna1a gene mutation.
Volume: 7
Issue: 8
Pages: e44230
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Publication
15003170 | J:88693
First Author: van den Maagdenberg AM
Year: 2004
Journal: Neuron
Title: A Cacna1a knockin migraine mouse model with increased susceptibility to cortical spreading depression.
Volume: 41
Issue: 5
Pages: 701-10
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Publication
23827678 | J:199996
First Author: Du X
Year: 2013
Journal: Cell
Title: Second cistron in CACNA1A gene encodes a transcription factor mediating cerebellar development and SCA6.
Volume: 154
Issue: 1
Pages: 118-33
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Publication
30649209 | J:294560
First Author: Loonen ICM
Year: 2019
Journal: Brain
Title: Brainstem spreading depolarization and cortical dynamics during fatal seizures in Cacna1a S218L mice.
Volume: 142
Issue: 2
Pages: 412-425
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Publication
21411672 | J:170451
First Author: Mark MD
Year: 2011
Journal: J Neurosci
Title: Delayed postnatal loss of P/Q-type calcium channels recapitulates the absence epilepsy, dyskinesia, and ataxia phenotypes of genomic Cacna1a mutations.
Volume: 31
Issue: 11
Pages: 4311-26
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Publication
24583041 | J:210330
 
First Author: Hullugundi SK
Year: 2014
Journal: Neuroscience
Title: A hyperexcitability phenotype in mouse trigeminal sensory neurons expressing the R192Q Cacna1a missense mutation of familial hemiplegic migraine type-1.
Volume: 266
Pages: 244-54
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Publication
11344116 | J:76459
First Author: Fletcher CF
Year: 2001
Journal: FASEB J
Title: Dystonia and cerebellar atrophy in Cacna1a null mice lacking P/Q calcium channel activity.
Volume: 15
Issue: 7
Pages: 1288-90
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Publication
19854154 | J:155607
First Author: Saito H
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Knockdown of Cav2.1 calcium channels is sufficient to induce neurological disorders observed in natural occurring Cacna1a mutants in mice.
Volume: 390
Issue: 3
Pages: 1029-33
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Publication
31800012 | J:293639
First Author: Miao QL
Year: 2020
Journal: Brain
Title: Adult loss of Cacna1a in mice recapitulates childhood absence epilepsy by distinct thalamic bursting mechanisms.
Volume: 143
Issue: 1
Pages: 161-174
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Publication
22005682 | J:191542
First Author: Fioretti B
Year: 2011
Journal: J Physiol
Title: Trigeminal ganglion neuron subtype-specific alterations of Ca(V)2.1 calcium current and excitability in a Cacna1a mouse model of migraine.
Volume: 589
Issue: Pt 23
Pages: 5879-95
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Publication
14657414 | -
First Author: Catterall WA
Year: 2003
Journal: Pharmacol Rev
Title: International Union of Pharmacology. XL. Compendium of voltage-gated ion channels: calcium channels.
Volume: 55
Issue: 4
Pages: 579-81
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Publication
11031246 | -
 
First Author: Catterall WA
Year: 2000
Journal: Annu Rev Cell Dev Biol
Title: Structure and regulation of voltage-gated Ca2+ channels.
Volume: 16
Pages: 521-55
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Publication
10774722 | J:61466
First Author: Ertel EA
Year: 2000
Journal: Neuron
Title: Nomenclature of voltage-gated calcium channels.
Volume: 25
Issue: 3
Pages: 533-5
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Publication
8825650 | -
First Author: Diriong S
Year: 1995
Journal: Genomics
Title: Chromosomal localization of the human genes for alpha 1A, alpha 1B, and alpha 1E voltage-dependent Ca2+ channel subunits.
Volume: 30
Issue: 3
Pages: 605-9
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Publication
16111830 | J:104354
First Author: Kaja S
Year: 2005
Journal: Neuroscience
Title: Gene dosage-dependent transmitter release changes at neuromuscular synapses of CACNA1A R192Q knockin mice are non-progressive and do not lead to morphological changes or muscle weakness.
Volume: 135
Issue: 1
Pages: 81-95
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Publication
23516282 | J:196594
First Author: Maejima T
Year: 2013
Journal: J Neurosci
Title: Postnatal loss of P/Q-type channels confined to rhombic-lip-derived neurons alters synaptic transmission at the parallel fiber to purkinje cell synapse and replicates genomic Cacna1a mutation phenotype of ataxia and seizures in mice.
Volume: 33
Issue: 12
Pages: 5162-74
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Publication
31628185 | J:282371
First Author: Jansen NA
Year: 2019
Journal: J Neurosci
Title: Apnea Associated with Brainstem Seizures in Cacna1a S218L Mice Is Caused by Medullary Spreading Depolarization.
Volume: 39
Issue: 48
Pages: 9633-9644
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Publication
- | J:198844
     
First Author: Harris BS
Year: 2013
Journal: MGI Direct Data Submission
Title: Small roller: A new recessive neurological mutation that maps to Chromosome 8
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Publication
- | J:267668
     
First Author: Keef J
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for totter.
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Publication
19484318 | J:164112
First Author: Plomp JJ
Year: 2009
Journal: Cerebellum
Title: The ataxic Cacna1a-mutant mouse rolling nagoya: an overview of neuromorphological and electrophysiological findings.
Volume: 8
Issue: 3
Pages: 222-30
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Publication
30922876 | J:276254
First Author: Du X
Year: 2019
Journal: Neuron
Title: α1ACT Is Essential for Survival and Early Cerebellar Programming in a Critical Neonatal Window.
Volume: 102
Issue: 4
Pages: 770-785.e7
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Publication
18687887 | J:139488
First Author: Watase K
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Spinocerebellar ataxia type 6 knockin mice develop a progressive neuronal dysfunction with age-dependent accumulation of mutant CaV2.1 channels.
Volume: 105
Issue: 33
Pages: 11987-92
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16242631 | J:102801
First Author: Fureman BE
Year: 2005
Journal: Neurobiol Dis
Title: Noradrenergic blockade prevents attacks in a model of episodic dysfunction caused by a channelopathy.
Volume: 20
Issue: 2
Pages: 227-32
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Publication
24768804 | J:214010
 
First Author: Salvi J
Year: 2014
Journal: Neurobiol Dis
Title: RNAi silencing of P/Q-type calcium channels in Purkinje neurons of adult mouse leads to episodic ataxia type 2.
Volume: 68
Pages: 47-56
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Publication
25109669 | J:217557
 
First Author: Rose SJ
Year: 2014
Journal: Exp Neurol
Title: The first knockin mouse model of episodic ataxia type 2.
Volume: 261
Pages: 553-62
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36078147 | J:329002
 
First Author: Chang HHV
Year: 2022
Journal: Cells
Title: Loss of Flocculus Purkinje Cell Firing Precision Leads to Impaired Gaze Stabilization in a Mouse Model of Spinocerebellar Ataxia Type 6 (SCA6).
Volume: 11
Issue: 17
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31337678 | J:277450
First Author: Miyoshi C
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Methodology and theoretical basis of forward genetic screening for sleep/wakefulness in mice.
Volume: 116
Issue: 32
Pages: 16062-16067
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11160387 | J:71860
First Author: Zwingman TA
Year: 2001
Journal: J Neurosci
Title: Rocker is a new variant of the voltage-dependent calcium channel gene Cacna1a.
Volume: 21
Issue: 4
Pages: 1169-78
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14724264 | J:194956
First Author: Stahl JS
Year: 2004
Journal: J Neurophysiol
Title: Eye movements of the murine P/Q calcium channel mutant rocker, and the impact of aging.
Volume: 91
Issue: 5
Pages: 2066-78
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21490217 | J:170969
First Author: Eikermann-Haerter K
Year: 2011
Journal: J Neurosci
Title: Enhanced subcortical spreading depression in familial hemiplegic migraine type 1 mutant mice.
Volume: 31
Issue: 15
Pages: 5755-63
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35238776 | J:321889
   
First Author: Terpollili NA
Year: 2022
Journal: Elife
Title: CaV2.1 channel mutations causing familial hemiplegic migraine type 1 increase the susceptibility for cortical spreading depolarizations and seizures and worsen outcome after experimental traumatic brain injury.
Volume: 11
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19104150 | J:144701
First Author: Eikermann-Haerter K
Year: 2009
Journal: J Clin Invest
Title: Genetic and hormonal factors modulate spreading depression and transient hemiparesis in mouse models of familial hemiplegic migraine type 1.
Volume: 119
Issue: 1
Pages: 99-109
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26208839 | J:226272
 
First Author: Kaja S
Year: 2015
Journal: Neuroscience
Title: Differential cerebellar GABAA receptor expression in mice with mutations in CaV2.1 (P/Q-type) calcium channels.
Volume: 304
Pages: 198-208
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22956801 | J:333615
First Author: Inchauspe CG
Year: 2012
Journal: J Neurophysiol
Title: Presynaptic CaV2.1 calcium channels carrying familial hemiplegic migraine mutation R192Q allow faster recovery from synaptic depression in mouse calyx of Held.
Volume: 108
Issue: 11
Pages: 2967-76
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20186955 | J:211767
First Author: van den Maagdenberg AM
Year: 2010
Journal: Ann Neurol
Title: High cortical spreading depression susceptibility and migraine-associated symptoms in Ca(v)2.1 S218L mice.
Volume: 67
Issue: 1
Pages: 85-98
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25716839 | J:219849
First Author: Dilekoz E
Year: 2015
Journal: J Neurosci
Title: Migraine mutations impair hippocampal learning despite enhanced long-term potentiation.
Volume: 35
Issue: 8
Pages: 3397-402
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34077522 | J:322324
First Author: Bohne P
Year: 2021
Journal: Hum Mol Genet
Title: Cognitive deficits in episodic ataxia type 2 mouse models.
Volume: 30
Issue: 19
Pages: 1811-1832
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21870131 | J:234599
First Author: Todorov B
Year: 2012
Journal: Cerebellum
Title: Purkinje cell-specific ablation of Cav2.1 channels is sufficient to cause cerebellar ataxia in mice.
Volume: 11
Issue: 1
Pages: 246-58
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26887908 | J:278031
First Author: Kim TY
Year: 2016
Journal: Exp Anim
Title: Protein expression pattern in cerebellum of Cav2.1 mutant, tottering-6j mice.
Volume: 65
Issue: 3
Pages: 207-14
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17513018 | J:140908
First Author: Alonso I
Year: 2008
Journal: Neurobiol Aging
Title: Motor and cognitive deficits in the heterozygous leaner mouse, a Cav2.1 voltage-gated Ca2+ channel mutant.
Volume: 29
Issue: 11
Pages: 1733-43
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18093175 | J:132196
First Author: Ovsepian SV
Year: 2008
Journal: Eur J Neurosci
Title: The leaner P/Q-type calcium channel mutation renders cerebellar Purkinje neurons hyper-excitable and eliminates Ca2+-Na+ spike bursts.
Volume: 27
Issue: 1
Pages: 93-103
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Publication
17161543 | J:121290
First Author: Kaja S
Year: 2007
Journal: Neuroscience
Title: Characterization of acetylcholine release and the compensatory contribution of non-Ca(v)2.1 channels at motor nerve terminals of leaner Ca(v)2.1-mutant mice.
Volume: 144
Issue: 4
Pages: 1278-87
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17439489 | J:125038
First Author: Kaja S
Year: 2007
Journal: Eur J Neurosci
Title: Severely impaired neuromuscular synaptic transmission causes muscle weakness in the Cacna1a-mutant mouse rolling Nagoya.
Volume: 25
Issue: 7
Pages: 2009-20
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Publication
19850086 | J:156904
First Author: Takahashi E
Year: 2010
Journal: Behav Brain Res
Title: Neonatal motor functions in Cacna1a-mutant rolling Nagoya mice.
Volume: 207
Issue: 2
Pages: 273-9
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24849341 | J:211350
First Author: Di Guilmi MN
Year: 2014
Journal: J Neurosci
Title: Synaptic gain-of-function effects of mutant Cav2.1 channels in a mouse model of familial hemiplegic migraine are due to increased basal [Ca2+]i.
Volume: 34
Issue: 21
Pages: 7047-58
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Publication
23115190 | J:192290
First Author: Gao Z
Year: 2012
Journal: J Neurosci
Title: Cerebellar ataxia by enhanced Ca(V)2.1 currents is alleviated by Ca2+-dependent K+-channel activators in Cacna1a(S218L) mutant mice.
Volume: 32
Issue: 44
Pages: 15533-46
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25855180 | J:221681
First Author: Cramer SW
Year: 2015
Journal: J Neurosci
Title: Abnormal excitability and episodic low-frequency oscillations in the cerebral cortex of the tottering mouse.
Volume: 35
Issue: 14
Pages: 5664-79
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17188510 | J:123243
First Author: Saegusa H
Year: 2007
Journal: Mol Cell Neurosci
Title: Properties of human Cav2.1 channel with a spinocerebellar ataxia type 6 mutation expressed in Purkinje cells.
Volume: 34
Issue: 2
Pages: 261-70
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17982453 | J:130784
First Author: Glasscock E
Year: 2007
Journal: Nat Neurosci
Title: Masking epilepsy by combining two epilepsy genes.
Volume: 10
Issue: 12
Pages: 1554-8
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23451282 | J:199328
First Author: Stahl JS
Year: 2013
Journal: PLoS One
Title: 4-aminopyridine does not enhance flocculus function in tottering, a mouse model of vestibulocerebellar dysfunction and ataxia.
Volume: 8
Issue: 2
Pages: e57895
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Publication
24355314 | J:211481
 
First Author: Park J
Year: 2014
Journal: Neurobiol Dis
Title: Differential trigeminovascular nociceptive responses in the thalamus in the familial hemiplegic migraine 1 knock-in mouse: a Fos protein study.
Volume: 64
Pages: 1-7
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Publication
25481823 | J:237437
 
First Author: Inchauspe CG
Year: 2015
Journal: Hear Res
Title: Familial hemiplegic migraine type-1 mutated cav2.1 calcium channels alter inhibitory and excitatory synaptic transmission in the lateral superior olive of mice.
Volume: 319
Pages: 56-68
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26758833 | J:228867
First Author: Bomben VC
Year: 2016
Journal: J Neurosci
Title: Isolated P/Q Calcium Channel Deletion in Layer VI Corticothalamic Neurons Generates Absence Epilepsy.
Volume: 36
Issue: 2
Pages: 405-18
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Publication
11756409 | J:75166
First Author: Tsunemi T
Year: 2002
Journal: J Biol Chem
Title: Novel Cav2.1 splice variants isolated from Purkinje cells do not generate P-type Ca2+ current.
Volume: 277
Issue: 9
Pages: 7214-21
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23426690 | J:195984
First Author: Koch H
Year: 2013
Journal: J Neurosci
Title: Stable respiratory activity requires both P/Q-type and N-type voltage-gated calcium channels.
Volume: 33
Issue: 8
Pages: 3633-45
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23577145 | J:200145
First Author: Hullugundi SK
Year: 2013
Journal: PLoS One
Title: The mechanism of functional up-regulation of P2X3 receptors of trigeminal sensory neurons in a genetic mouse model of familial hemiplegic migraine type 1 (FHM-1).
Volume: 8
Issue: 4
Pages: e60677
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17376154 | J:119639
First Author: Xie G
Year: 2007
Journal: Genes Brain Behav
Title: Forward genetic screen of mouse reveals dominant missense mutation in the P/Q-type voltage-dependent calcium channel, CACNA1A.
Volume: 6
Issue: 8
Pages: 717-27
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18597946 | J:137816
First Author: Miki T
Year: 2008
Journal: Neuroscience
Title: Two novel alleles of tottering with distinct Ca(v)2.1 calcium channel neuropathologies.
Volume: 155
Issue: 1
Pages: 31-44
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24205277 | J:209226
First Author: Mallmann RT
Year: 2013
Journal: PLoS One
Title: Ablation of Ca(V)2.1 voltage-gated Ca²⁺ channels in mouse forebrain generates multiple cognitive impairments.
Volume: 8
Issue: 10
Pages: e78598
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24758835 | J:303241
First Author: Yoshimoto T
Year: 2014
Journal: J Vet Med Sci
Title: Rolling Nagoya mouse strain (PROD-rol/rol) with classic piebald mutation.
Volume: 76
Issue: 8
Pages: 1093-8
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16381801 | J:135773
First Author: Kaja S
Year: 2006
Journal: J Neurophysiol
Title: Compensatory contribution of Cav2.3 channels to acetylcholine release at the neuromuscular junction of tottering mice.
Volume: 95
Issue: 4
Pages: 2698-704
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33305180 | J:306911
First Author: Yamashiro K
Year: 2020
Journal: iScience
Title: AUTS2 Governs Cerebellar Development, Purkinje Cell Maturation, Motor Function and Social Communication.
Volume: 23
Issue: 12
Pages: 101820
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- | J:338850
     
First Author: Meyer KJ
Year: 2023
Journal: MGI Direct Data Submission
Title: Direct Data Submission of Multiple Allele.
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23595603 | J:317577
First Author: Rossignol E
Year: 2013
Journal: Ann Neurol
Title: CaV 2.1 ablation in cortical interneurons selectively impairs fast-spiking basket cells and causes generalized seizures.
Volume: 74
Issue: 2
Pages: 209-22
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10381343 | J:55900
First Author: Takahashi E
Year: 1999
Journal: Biochem Biophys Res Commun
Title: Isolation and functional characterization of the 5'-upstream region of mouse P/Q-type Ca2+ channel alpha1A subunit gene.
Volume: 260
Issue: 1
Pages: 54-9
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10611370 | J:59076
First Author: Jun K
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Ablation of P/Q-type Ca(2+) channel currents, altered synaptic transmission, and progressive ataxia in mice lacking the alpha(1A)-subunit.
Volume: 96
Issue: 26
Pages: 15245-50
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12065603 | J:76879
First Author: Aldea M
Year: 2002
Journal: J Neurochem
Title: A perforated patch-clamp study of calcium currents and exocytosis in chromaffin cells of wild-type and alpha(1A) knockout mice.
Volume: 81
Issue: 5
Pages: 911-21
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22279211 | J:180584
First Author: Lin KH
Year: 2012
Journal: J Neurosci
Title: Similar intracellular Ca2+ requirements for inactivation and facilitation of voltage-gated Ca2+ channels in a glutamatergic mammalian nerve terminal.
Volume: 32
Issue: 4
Pages: 1261-72
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14990796 | J:88887
First Author: Piedras-Rentería ES
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Presynaptic homeostasis at CNS nerve terminals compensates for lack of a key Ca2+ entry pathway.
Volume: 101
Issue: 10
Pages: 3609-14
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14667443 | J:91282
First Author: Pagani R
Year: 2004
Journal: Neuroscience
Title: Differential expression of alpha 1 and beta subunits of voltage dependent Ca2+ channel at the neuromuscular junction of normal and P/Q Ca2+ channel knockout mouse.
Volume: 123
Issue: 1
Pages: 75-85
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18982062 | J:143914
First Author: Katoh A
Year: 2008
Journal: PLoS One
Title: Disruption of learned timing in P/Q calcium channel mutants.
Volume: 3
Issue: 11
Pages: e3635
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12401561 | J:107960
First Author: Cavelier P
Year: 2002
Journal: Neurosci Lett
Title: Cerebellar slice cultures from mice lacking the P/Q calcium channel: electroresponsiveness of Purkinje cells.
Volume: 333
Issue: 1
Pages: 64-8
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24225482 | J:279624
 
First Author: Kawamura Y
Year: 2013
Journal: Nat Commun
Title: Spike timing-dependent selective strengthening of single climbing fibre inputs to Purkinje cells during cerebellar development.
Volume: 4
Pages: 2732
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14973254 | J:90116
First Author: Miyazaki T
Year: 2004
Journal: J Neurosci
Title: P/Q-type Ca2+ channel alpha1A regulates synaptic competition on developing cerebellar Purkinje cells.
Volume: 24
Issue: 7
Pages: 1734-43
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12624181 | J:82722
First Author: Urbano FJ
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Altered properties of quantal neurotransmitter release at endplates of mice lacking P/Q-type Ca2+ channels.
Volume: 100
Issue: 6
Pages: 3491-6
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Publication
20092572 | J:157629
First Author: Lonchamp E
Year: 2009
Journal: Eur J Neurosci
Title: Deletion of Cav2.1(alpha1(A)) subunit of Ca2+-channels impairs synaptic GABA and glutamate release in the mouse cerebellar cortex in cultured slices.
Volume: 30
Issue: 12
Pages: 2293-307
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15548652 | J:96814
First Author: Inchauspe CG
Year: 2004
Journal: J Neurosci
Title: Functional compensation of P/Q by N-type channels blocks short-term plasticity at the calyx of Held presynaptic terminal.
Volume: 24
Issue: 46
Pages: 10379-83
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17968008 | J:127152
First Author: Llinás RR
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Gamma-band deficiency and abnormal thalamocortical activity in P/Q-type channel mutant mice.
Volume: 104
Issue: 45
Pages: 17819-24
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Publication
21718757 | J:176694
 
First Author: Giugovaz-Tropper B
Year: 2011
Journal: Neuroscience
Title: P/Q-type calcium channel ablation in a mice glycinergic synapse mediated by multiple types of Ca²+ channels alters transmitter release and short term plasticity.
Volume: 192
Pages: 219-30
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Publication
17823210 | J:140823
First Author: Inchauspe CG
Year: 2007
Journal: J Physiol
Title: Changes in synaptic transmission properties due to the expression of N-type calcium channels at the calyx of Held synapse of mice lacking P/Q-type calcium channels.
Volume: 584
Issue: Pt 3
Pages: 835-51
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Publication
17005620 | J:135841
First Author: Katoh A
Year: 2007
Journal: J Neurophysiol
Title: Motor deficits in homozygous and heterozygous p/q-type calcium channel mutants.
Volume: 97
Issue: 2
Pages: 1280-7
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Publication
27381005 | J:271407
 
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Journal: Hum Mol Genet
Title: Alternative splicing in the C-terminal tail of Cav2.1 is essential for preventing a neurological disease in mice.
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Journal: Eur J Neurosci
Title: A CaV2.1 calcium channel mutation rocker reduces the number of postsynaptic AMPA receptors in parallel fiber-Purkinje cell synapses.
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Title: Enhanced Feedback Inhibition Due to Increased Recruitment of Somatostatin-Expressing Interneurons and Enhanced Cortical Recurrent Excitation in a Genetic Mouse Model of Migraine.
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Title: Enhanced Thalamocortical Synaptic Transmission and Dysregulation of the Excitatory-Inhibitory Balance at the Thalamocortical Feedforward Inhibitory Microcircuit in a Genetic Mouse Model of Migraine.
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Title: Hyperpolarization-activated current Ih in mouse trigeminal sensory neurons in a transgenic mouse model of familial hemiplegic migraine type-1.
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