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Search results 301 to 359 out of 359 for Gdf11

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0.021s
Type Details Score
Publication
First Author: Economides AN
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Conditionals by inversion provide a universal method for the generation of conditional alleles.
Volume: 110
Issue: 34
Pages: E3179-88
Publication
First Author: Mao CA
Year: 2008
Journal: Development
Title: Rewiring the retinal ganglion cell gene regulatory network: Neurod1 promotes retinal ganglion cell fate in the absence of Math5.
Volume: 135
Issue: 20
Pages: 3379-88
Publication
First Author: Jurberg AD
Year: 2014
Journal: Dev Biol
Title: Compartment-dependent activities of Wnt3a/β-catenin signaling during vertebrate axial extension.
Volume: 394
Issue: 2
Pages: 253-63
Publication
First Author: Wang W
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: The TGFβ type I receptor TGFβRI functions as an inhibitor of BMP signaling in cartilage.
Volume: 116
Issue: 31
Pages: 15570-15579
Publication
First Author: Pitera JE
Year: 2008
Journal: Hum Mol Genet
Title: Fras1, a basement membrane-associated protein mutated in Fraser syndrome, mediates both the initiation of the mammalian kidney and the integrity of renal glomeruli.
Volume: 17
Issue: 24
Pages: 3953-64
Publication
First Author: Oliver-Krasinski JM
Year: 2009
Journal: J Clin Invest
Title: The diabetes gene Pdx1 regulates the transcriptional network of pancreatic endocrine progenitor cells in mice.
Volume: 119
Issue: 7
Pages: 1888-98
Publication
First Author: Young T
Year: 2009
Journal: Dev Cell
Title: Cdx and Hox genes differentially regulate posterior axial growth in mammalian embryos.
Volume: 17
Issue: 4
Pages: 516-26
Publication    
First Author: Dias A
Year: 2020
Journal: Elife
Title: A Tgfbr1/Snai1-dependent developmental module at the core of vertebrate axial elongation.
Volume: 9
Publication
First Author: Yates LL
Year: 2010
Journal: Hum Mol Genet
Title: The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation.
Volume: 19
Issue: 23
Pages: 4663-76
Publication
First Author: Hu B
Year: 2012
Journal: Cell
Title: Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling.
Volume: 149
Issue: 6
Pages: 1207-20
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
Publication
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Camaschella C
Year: 2019
Journal: Blood
Title: GDF11 is not the target of luspatercept.
Volume: 134
Issue: 6
Pages: 500-501
Publication
First Author: Bajikar SS
Year: 2017
Journal: Dev Cell
Title: Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer.
Volume: 43
Issue: 4
Pages: 418-435.e13
Publication
First Author: Sinha M
Year: 2014
Journal: Science
Title: Restoring systemic GDF11 levels reverses age-related dysfunction in mouse skeletal muscle.
Volume: 344
Issue: 6184
Pages: 649-52
Publication  
First Author: Liu W
Year: 2016
Journal: Nat Commun
Title: GDF11 decreases bone mass by stimulating osteoclastogenesis and inhibiting osteoblast differentiation.
Volume: 7
Pages: 12794
Publication  
First Author: Saito S
Year: 2024
Journal: Front Cell Dev Biol
Title: Functional analysis of a first hindlimb positioning enhancer via Gdf11 expression.
Volume: 12
Pages: 1302141
DO Term
Publication
First Author: Ge G
Year: 2005
Journal: Mol Cell Biol
Title: GDF11 forms a bone morphogenetic protein 1-activated latent complex that can modulate nerve growth factor-induced differentiation of PC12 cells.
Volume: 25
Issue: 14
Pages: 5846-58
Allele  
Name: myostatin; endonuclease-mediated mutation 2, Richard T Lee
Allele Type: Endonuclease-mediated
Publication
First Author: Kondás K
Year: 2011
Journal: Biochem Soc Trans
Title: Biological functions of the WAP domain-containing multidomain proteins WFIKKN1 and WFIKKN2.
Volume: 39
Issue: 5
Pages: 1416-20
Publication
First Author: Trexler M
Year: 2002
Journal: Biol Chem
Title: Distinct expression pattern of two related human proteins containing multiple types of protease-inhibitory modules.
Volume: 383
Issue: 1
Pages: 223-8
Protein Domain
Type: Family
Description: WFIKKN proteins are secreted multidomain proteins containing a WAP (whey acidic protein)-, a follistatin/Kazal-, an immunoglobulin-, two Kunitz-type protease inhibitor-domains, and an NTR (netrin) domain. They have been reported to inhibit the activity of trypsin, and to bind GDF11 (growth and differentiation factor 11) and myostatin (GDF8) []. Due to the presence of multiple domains that frequently serve as protease inhibitors, WFIKKN proteins are presumed to control the action of diverse serine proteases as well as metalloproteinases [].In humans, WFIKKN1 expression is observed in pancreas, liver, thymus, kidney, testis and lung and WFIKKN2 (also known as WFIKKNRP) expression is observed in ovary, testis, pancreas, brain and lung [].
HT Experiment  
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Walker RG
Year: 2017
Journal: BMC Biol
Title: Structural basis for potency differences between GDF8 and GDF11.
Volume: 15
Issue: 1
Pages: 19
Publication
First Author: Nomura T
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Skeletal muscle-derived progenitors capable of differentiating into cardiomyocytes proliferate through myostatin-independent TGF-beta family signaling.
Volume: 365
Issue: 4
Pages: 863-9
Publication
First Author: Wang F
Year: 2015
Journal: Oncotarget
Title: Splenocytes derived from young WT mice prevent AD progression in APPswe/PSENldE9 transgenic mice.
Volume: 6
Issue: 25
Pages: 20851-62
Publication
First Author: Schneyer AL
Year: 2008
Journal: Endocrinology
Title: Differential antagonism of activin, myostatin and growth and differentiation factor 11 by wild-type and mutant follistatin.
Volume: 149
Issue: 9
Pages: 4589-95
Publication
First Author: Harper SC
Year: 2016
Journal: Circ Res
Title: Is Growth Differentiation Factor 11 a Realistic Therapeutic for Aging-Dependent Muscle Defects?
Volume: 118
Issue: 7
Pages: 1143-50; discussion 1150
Protein
Organism: Mus musculus/domesticus
Length: 272  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 552  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 571  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 518  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 571  
Fragment?: false